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https://www.readbyqxmd.com/read/28230421/medicare-expenditure-correlates-of-atrophy-and-cerebrovascular-disease-in-older-adults
#1
Briana S Last, Maria-José García Rubio, Carolyn W Zhu, Stephanie Cosentino, Jennifer J Manly, Charles DeCarli, Yaakov Stern, Adam M Brickman
: Background/Study Context: Magnetic resonance imaging (MRI) markers of cerebrovascular disease and atrophy are common in older adults and are associated with cognitive and medical burden. However, the extent to which they are related to health care expenditures has not been examined. We studied whether increased Medicare expenditures were associated with brain markers of atrophy and cerebrovascular disease in older adults. METHODS: A subset of participants (n = 592; mean age = 80 years; 66% women) from the Washington Heights Inwood Columbia Aging Project (WHICAP), a community-based observational study of aging in upper Manhattan, received high-resolution MRI and had Medicare expenditure data on file...
March 2017: Experimental Aging Research
https://www.readbyqxmd.com/read/28229384/relationship-of-meteorological-factors-and-acute-stroke-events-in-kaunas-lithuania-in-2000-2010
#2
Laura Tamasauskiene, Daiva Rastenyte, Ricardas Radisauskas, Abdonas Tamosiunas, Domantas Tamasauskas, Vidmantas Vaiciulis, Daina Kranciukaite-Butylkiniene, Egle Milinaviciene
Some researchers have hypothesised that meteorological factors may have an impact on acute cerebrovascular diseases. The aim of this study was to determine an impact of some meteorological factors on occurrence of acute cerebrovascular events in the middle-aged Kaunas population. Kaunas stroke register data were used. Data on meteorological factors for the time period from 2000 to 2010 were obtained from the Lithuanian Hydrometeorological Service Kaunas Meteorological Station. We analysed 4038 cases with stroke...
February 23, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28229127/the-application-of-retinal-fundus-camera-imaging-in-dementia-a-systematic-review
#3
REVIEW
Sarah McGrory, James R Cameron, Enrico Pellegrini, Claire Warren, Fergus N Doubal, Ian J Deary, Baljean Dhillon, Joanna M Wardlaw, Emanuele Trucco, Thomas J MacGillivray
INTRODUCTION: The ease of imaging the retinal vasculature, and the evolving evidence suggesting this microvascular bed might reflect the cerebral microvasculature, presents an opportunity to investigate cerebrovascular disease and the contribution of microvascular disease to dementia with fundus camera imaging. METHODS: A systematic review and meta-analysis was carried out to assess the measurement of retinal properties in dementia using fundus imaging. RESULTS: Ten studies assessing retinal properties in dementia were included...
2017: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
https://www.readbyqxmd.com/read/28228887/transarterial-embolization-of-a-hyperfunctioning-aldosteronoma-in-a-patient-with-bilateral-adrenal-nodules
#4
Jason T Salsamendi, Francisco J Gortes, Alejandro R Ayala, Juan D Palacios, Sanjit Tewari, Govindarajan Narayanan
Primary hyperaldosteronism often results in resistant hypertension and hypokalemia, which may lead to cardiovascular and cerebrovascular complications. Although surgery is first line treatment for unilateral functioning aldosteronomas, minimally invasive therapies may be first line for certain patients such as those who cannot tolerate surgery. We present a case of transarterial embolization (TAE) of an aldosteronoma. The patient presented with a cerebrovascular accident, and subsequently developed uncontrolled hypertension, hypokalemia, and a myocardial infarction...
March 2017: Radiology case reports
https://www.readbyqxmd.com/read/28226789/detection-of-intention-of-pedaling-start-cycle-through-eeg-signals
#5
Marisol Rodriguez-Ugarte, Enrique Hortal, Alvaro Costa, Eduardo Ianez, Andres Ubeda, Jose M Azorin, Marisol Rodriguez-Ugarte, Enrique Hortal, Alvaro Costa, Eduardo Ianez, Andres Ubeda, Jose M Azorin, Eduardo Ianez, Enrique Hortal, Alvaro Costa, Andres Ubeda, Marisol Rodriguez-Ugarte, Jose M Azorin
Recovery from cerebrovascular accident (CVA) is a growing research topic. Exoskeletons are being used for this purpose in combination with a volitional control algorithm. This work studied the intention of pedaling initiation movement, based on previous work, with different types of electrode configuration and different processing time windows. The main characteristic is to find alterations in the mu and beta frequency bands where ERD/ERS is produced. The results show that for the majority of the subjects this event is well detected with 8 or 9 electrodes and using time before and after the movement onset...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226702/estimation-of-voxel-wise-dynamic-cerebrovascular-reactivity-curves-from-resting-state-fmri-data
#6
Prokopis C Prokopiou, Kevin Murphy, Richard G Wise, Georgios D Mitsis, Prokopis C Prokopiou, Kevin Murphy, Richard G Wise, Georgios D Mitsis, Prokopis C Prokopiou, Georgios D Mitsis, Richard G Wise, Kevin Murphy
In this work, we investigate the linear dynamic interactions between fluctuations in arterial CO2 that occur during normal breathing, and the BOLD fMRI signal. We cast this problem within a systems-theoretic framework, where we employ functional expansions for the estimation of the impulse responses in large regions of interest, as well as in individual voxels. We also implement classification schemes in order to identify different brain regions with similar cerebrovascular reactivity characteristics. Our results reveal that it is feasible to obtain reliable estimates of cerebrovascular reactivity curves from resting-state data and that these curves exhibit considerable variability across different brain regions that may be related to the underlying anatomy...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226691/structural-changes-of-cingulate-cortex-in-post-stroke-depression
#7
Chenfei Ye, Jun Wu, Xuhui Chen, Changle Zhang, Hengtong Li, Shuai Mao, Heather T Ma, Chenfei Ye, Jun Wu, Xuhui Chen, Changle Zhang, Hengtong Li, Shuai Mao, Heather T Ma, Shuai Mao, Heather T Ma, Jun Wu, Hengtong Li, Changle Zhang, Chenfei Ye, Xuhui Chen
Disruption of neural connections among regions regulating mood and cognition rather than cerebrovascular lesions may contribute to post-stroke depression (PSD). In this paper, we hypothesized that structural abnormalities in white matter structure like cingulate cortex induced by focal infarcts would play a role in mood regulation or depression after stroke onset. Various DTI coefficients including FA, RD and ADC with multiple signal distribution measurements were collected and statistically analyzed. The results identify significant differences in volume and multiple diffusion indices of DTI intensity distribution in cingulate cortex between PSD patients and the normal control...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226032/risk-of-vertebral-fracture-in-patients-diagnosed-with-a-depressive-disorder-a-nationwide-population-based-cohort-study
#8
Shyh-Chyang Lee, Li-Yu Hu, Min-Wei Huang, Cheng-Che Shen, Wei-Lun Huang, Ti Lu, Chiao-Lin Hsu, Chih-Chuan Pan
OBJECTIVE: Previous studies have reported that depression may play a crucial role in the occurrence of vertebral fractures. However, a clear correlation between depressive disorders and osteoporotic fractures has not been established. We explored the association between depressive disorders and subsequent new-onset vertebral fractures. Additionally, we aimed to identify the potential risk factors for vertebral fracture in patients with a depressive disorder. METHODS: We studied patients listed in the Taiwan National Health Insurance Research Database who were diagnosed with a depressive disorder by a psychiatrist...
January 1, 2017: Clinics
https://www.readbyqxmd.com/read/28224671/outcomes-after-diagnosis-of-mild-cognitive-impairment-in-a-large-autopsy-series
#9
Erin L Abner, Richard J Kryscio, Frederick A Schmitt, David W Fardo, Daniela C Moga, Eseosa T Ighodaro, Gregory A Jicha, Lei Yu, Hiroko H Dodge, Chengjie Xiong, Randall L Woltjer, Julie A Schneider, Nigel J Cairns, David A Bennett, Peter T Nelson
OBJECTIVE: Determine clinical and neuropathological outcomes following a clinical diagnosis of mild cognitive impairment (MCI). METHODS: Data were drawn from a large autopsy series (N=1,337) of individuals followed longitudinally from normal or MCI status to death, derived from four Alzheimer's Disease (AD) Centers in the United States. RESULTS: Mean follow-up was 7.9 years. Of the 874 individuals ever diagnosed with MCI, final clinical diagnoses were varied: 39...
February 22, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/28224248/vis-nir-spectroscopy-with-moving-window-pls-method-applied-to-rapid-analysis-of-whole-blood-viscosity
#10
Jiemei Chen, Zhiwei Yin, Yi Tang, Tao Pan
A rapid analytical method of human whole blood viscosity with low, medium, and high shear rates [WBV(L), WBV(M), and WBV(H), respectively] was developed using visible and near-infrared (Vis-NIR) spectroscopy combined with a moving-window partial least squares (MW-PLS) method. Two groups of peripheral blood samples were collected for modeling and validation. Separate analytical models were established for male and female groups to avoid interference in different gender groups and improve the homogeneity and prediction accuracy...
February 21, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28224216/vascular-surgery-the-main-risk-factor-for-mortality-in-146-takayasu-arteritis-patients
#11
Nilton Salles Rosa Neto, Samuel Katsuyuki Shinjo, Maurício Levy-Neto, Rosa Maria Rodrigues Pereira
Takayasu arteritis (TA) is an idiopathic chronic inflammatory disease that affects the aorta and its main branches. According to disease involvement, patients may require surgical treatment mainly due ischemic lesions in association with medical therapy. We evaluated the impact of vascular interventions in a cohort of TA patients. Medical records from 146 TA patients were reviewed. Clinical features, medical, and surgical treatment were revised and disease activity was determined by clinical, laboratorial, and imaging parameters...
February 21, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28223486/serum-borne-bioactivity-caused-by-pulmonary-multiwalled-carbon-nanotubes-induces-neuroinflammation-via-blood-brain-barrier-impairment
#12
Mario J Aragon, Lauren Topper, Christina R Tyler, Bethany Sanchez, Katherine Zychowski, Tamara Young, Guy Herbert, Pamela Hall, Aaron Erdely, Tracy Eye, Lindsey Bishop, Samantha A Saunders, Pretal P Muldoon, Andrew K Ottens, Matthew J Campen
Pulmonary exposure to multiwalled carbon nanotubes (MWCNTs) causes indirect systemic inflammation through unknown pathways. MWCNTs translocate only minimally from the lungs into the systemic circulation, suggesting that extrapulmonary toxicity may be caused indirectly by lung-derived factors entering the circulation. To assess a role for MWCNT-induced circulating factors in driving neuroinflammatory outcomes, mice were acutely exposed to MWCNTs (10 or 40 µg/mouse) via oropharyngeal aspiration. At 4 h after MWCNT exposure, broad disruption of the blood-brain barrier (BBB) was observed across the capillary bed with the small molecule fluorescein, concomitant with reactive astrocytosis...
February 21, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28223049/outcomes-of-coronary-artery-bypass-and-stents-for-unprotected-left-main-coronary-stenosis
#13
Yin-Shu Chang, Jia-Xiang Wang, Da-Wei Chang
BACKGROUND: This study assessed the short-, medium-, and long-term outcomes of coronary artery bypass grafting vs stenting for patients with unprotected left main coronary artery disease through a meta-analysis of randomized controlled trials. METHODS: PubMed, Embase, Scopus, Web of Science, Cochrane Library, and major conference proceedings databases were systematically searched for randomized controlled trials of coronary artery bypass grafting compared with stents in unprotected left main coronary artery disease...
February 18, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28222969/patient-tumour-and-treatment-factors-affect-complication-rates-in-soft-tissue-sarcoma-flap-reconstruction-in-a-synergistic-manner
#14
J Slump, P C Ferguson, J S Wunder, A M Griffin, H J Hoekstra, X Liu, S O P Hofer, A C O'Neill
INTRODUCTION: Flap reconstruction plays an essential role in the management of soft tissue sarcoma, facilitating wide resection while maximizing preservation of function. The addition of reconstruction increases the complexity of the surgery and identification of patients who are at high risk for post-operative complications is an important part of the preoperative assessment. This study examines predictors of complications in these patients. METHODS: 294 patients undergoing flap reconstruction following sarcoma resection were evaluated...
February 8, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28222615/clinical-associations-biological-risk-factors-and-outcomes-of-cerebral-venous-sinus-thrombosis
#15
Hafize Nalan Gunes, Burcu Gokce Cokal, Selda Keskin Guler, Tahir Kurtulus Yoldas, Umit Yavuz Malkan, Cemile Sencer Demircan, Mehmet Ilker Yon, Zeynep Yoldas, Gursel Gunes, Ibrahim Celalettin Haznedaroglu
Objective Cerebral venous sinus thrombosis (CVST) is a rare cerebrovascular disease affecting young adults. The majority of the patients are female. The aim of this study is to assess the clinical associations, risk factors and outcomes of the patients with CVST. Methods The data of 75 patients with CVST admitted to our hospital between 2006 and 2016 were reviewed. Demographic and clinical features and the thrombophilic risk factors of the patients were recorded. The localizations of the thrombi were determined and modified Rankin score at the time of onset and discharge were calculated...
December 2016: Journal of International Medical Research
https://www.readbyqxmd.com/read/28222542/ecologically-relevant-outcome-measure-for-post-inpatient-rehabilitation
#16
Carlos Marquez de la Plata, Devin Qualls, Patrick Plenger, James F Malec, Mary Ellen Hayden
BACKGROUND: Transfer of skills learned within the clinic environment to patients' home or community is important in post-inpatient brain injury rehabilitation (PBIR). Outcome measures used in PBIR assess level of independence during functional tasks; however, available functional instruments do not quantitate the environment in which the behaviors occur. OBJECTIVE: To examine the reliability and validity of an instrument used to assess patients' functional abilities while quantifying the amount of structure and distractions in the environment...
January 31, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28221268/moyamoya-syndrome-associated-with-hereditary-spherocytosis-an-emerging-clinical-entity
#17
Eleanor Gait-Carr, Daniel J A Connolly, David King
Moyamoya syndrome is an unusual cerebrovascular disorder, which has rarely been reported in association with hereditary spherocytosis. We present the case of a 6-year-old boy with hereditary spherocytosis who was diagnosed with Moyamoya syndrome following a stroke. We discuss why these conditions may coexist and briefly outline the management of such children.
February 17, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28220015/author-response-calcium-supplementation-and-risk-of-dementia-in-women-with-cerebrovascular-disease
#18
Silke Kern, Jürgen Kern, Kaj Blennow, Henrik Zetterberg, Margda Waern, Xinxin Guo, Anne Börjesson-Hanson, Ingmar Skoog, Svante Östling
No abstract text is available yet for this article.
February 21, 2017: Neurology
https://www.readbyqxmd.com/read/28220014/letter-re-calcium-supplementation-and-risk-of-dementia-in-women-with-cerebrovascular-disease
#19
David J Beale
No abstract text is available yet for this article.
February 21, 2017: Neurology
https://www.readbyqxmd.com/read/28220013/letter-re-calcium-supplementation-and-risk-of-dementia-in-women-with-cerebrovascular-disease
#20
Gilad Rosenberg
No abstract text is available yet for this article.
February 21, 2017: Neurology
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