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optical coherence tomograph

V A Shaimova, T B Shaimov, R B Shaimov, A Yu Galin, Zh A Goloshchapova, P K Ryzhkov, A V Fomin
PURPOSE: To develop methods for evaluating effectiveness of YAG-laser vitreolysis of vitreous floaters. MATERIAL AND METHODS: The study included 144 patients (173 eyes) who had underwent YAG-laser vitreolysis and were under observation from 01.09.16 to 31.01.18. The patients were 34 to 86 years old (mean age 62.7±10.2 years), 28 (19.4%) patients were male, 116 (80.6%) - female. All patients underwent standard and additional examination: ultrasonography (Accutome B-scan plus, U...
2018: Vestnik Oftalmologii
Ivan Bozic, Xiaoyue Li, Yuankai Tao
The zebrafish is a robust model for studying human ophthalmic function and disease because of its fecundity, life-cycle, and similarities between its retinal structure and the human retina. Here, we demonstrate longitudinal in vivo imaging of retinal structure using optical coherence tomography (OCT) and noninvasive retinal vascular perfusion imaging using OCT angiography (OCT-A) in zebrafish. In addition, we present methods for retinal vascular segmentation and biometry to quantify vessel branch length, curvature, and angle...
March 1, 2018: Biomedical Optics Express
Elizabeth A F Schaefer, Rebecca E H Whiting, Jacqueline W Pearce, Bruce H Grahn, Charles W Hamm, Cecil P Moore, Kristina L Narfström
A 11-year-old neutered male Labrador retriever-cross dog was presented to the University of Missouri-Columbia Veterinary Ophthalmology Service for subtle visual deficits. Indirect ophthalmoscopy revealed a smooth, bullous elevation in the superior-temporal retina OU. Optical coherence tomography (OCT) performed OU showed inner retinal separation consistent with retinoschisis. Electroretinography (ERG) revealed markedly reduced b-wave amplitudes in the more severely affected eye (OD) compared with the less severely affected eye (OS)...
March 8, 2018: Veterinary Ophthalmology
A Boyde
Laser ablation machining or microtomy (LAM) is a relatively new approach to producing slide mounted sections of translucent materials. We evaluated the method with a variety of problems from the bone, joint and dental tissues fields where we require thin undecalcified and undistorted sections for correlative light microscopy (LM) and backscattered electron scanning electron microscopy (BSE SEM). All samples were embedded in poly-methylmethacrlate (PMMA) and flat block surfaces had been previously studied by BSE-SEM and confocal scanning light microscopy (CSLM)...
February 27, 2018: Journal of Microscopy
Simon Schröder, Stephanie Mäurer, Timo Eppig, Berthold Seitz, Kathrin Rubly, Achim Langenbucher
PURPOSE: To compare corneal tomography and its statistical uncertainty for measurements obtained by three clinically used corneal tomographers: A Scheimpflug camera (Pentacam HR), a swept source optical coherence tomography system (CASIA SS-1000), and Placido ring imaging (TMS-5). MATERIAL AND METHODS: Repeated measurements with all three devices on 34 normal eyes were used to estimate the repeatability, precision, and mean values of corneal elevation and pachymetry within 8 mm diameter...
February 26, 2018: Current Eye Research
Giorgia Capocasale, Vera Panzarella, Vito Rodolico, Olga Di Fede, Giuseppina Campisi
There is currently a growing interest in new diagnostic tools of the oral cavity and mucosa which are non-invasive, repeatable and reliable. A diagnosis of a suspected, autoimmune pathology was made regarding a 57-year-old patient with desquamative gingivitis. However, a negative Nikolsky's sign did not seem to indicate a diagnosis of mucous membrane pemphigoid neither was there any indication as to the optimum location for an incisional biopsy. As an imaging method, the use of optical coherence tomography (OCT) has enabled the obtaining of tomographic (cross-sectional) scans of tissue...
February 26, 2018: Journal of Dermatology
Yuta Goto, Atsushi Okamoto, Atsushi Shibukawa, Kazuhisa Ogawa, Akihisa Tomita
We propose a virtual phase conjugation (VPC) based optical tomography (VPC-OT) for realizing single-shot optical tomographic imaging systems. Using a computer-based numerical beam propagation, the VPC combines pre-modulation and post-demodulation of the probe beam's wavefront, which provides an optical sectioning capability for resolving the depth coordinates. In VPC-OT, the physical optical microscope system and VPC are coupled using digital holography. Therefore, in contrast to conventional optical tomographic imaging (OTI) systems, this method does not require additional elements such as low-coherence light sources or confocal pinholes...
February 19, 2018: Optics Express
Chandrakumar Balaratnasingam, Dong An, Yoichi Sakurada, Cecilia S Lee, Aaron Y Lee, Ian L McAllister, K Bailey Freund, Marinko Sarunic, Dao-Yi Yu
PURPOSE: To use the capillary-free zone along retinal arteries, a physiologic area of superficial avascularization, as an anatomic paradigm to investigate the reliability of optical coherence tomographic angiography (OCTA) for visualizing the deep retinal circulation. DESIGN: Validity analysis and laboratory investigation. METHODS: Five normal human donor eyes (mean age 69.8 years) were perfusion-labelled with endothelial antibodies and the capillary networks of the perifovea were visualized using confocal scanning laser microscopy...
February 19, 2018: American Journal of Ophthalmology
Takehito Iwase, Hirotaka Yokouchi, Sonoko Misawa, Toshiyuki Oshitari, Takayuki Baba, Satoshi Kuwabara, Shuichi Yamamoto
The authors present findings in a 39-year-old man with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome with bilateral optic disc oedema. He was successfully treated with bortezomib and dexamethasone followed by autologous peripheral blood stem cell transplantation. The peripapillary retinal thickness was reduced in the optical coherence tomographic (OCT) images along with a decrease of the serum vascular endothelial growth factor (VEGF) levels. The authors recommend OCT to monitor the changes in the signs of POEMS syndrome after treatments...
February 2018: Neuro-ophthalmology
Peng Li, Andrew Maiden
Ptychography is a form of Coherent Diffractive Imaging, where diffraction patterns are processed by iterative algorithms to recover an image of a specimen. Although mostly applied in two dimensions, ptychography can be extended to produce three dimensional images in two ways: via multi-slice ptychography or ptychographic tomography. Ptychographic tomography relies on 2D ptychography to supply projections to conventional tomographic algorithms, whilst multi-slice ptychography uses the redundancy in ptychographic data to split the reconstruction into a series of axial slices...
February 1, 2018: Scientific Reports
Z J Liu, B Shi, C C Deng, G X Xu, R Z Zhao, C Y Shen, Z L Wang, H L Liu
Objective: To explore the imaging characteristics and related influencing factors of in-stent neoatherosclerosis (ISNA) in patients with restenosis after drug-eluting stent(DES) implantation with optical coherence tomography(OCT). Methods: A total of 25 cases of coronary heart disease patients(DES placement time ≥8 months) with coronary artery angiography showing DES in-stent restenosis (ISR) in Zunyi medical college affiliated hospital from July 2013 to December 2015 were included in this study and patient's data were retrospectively analyzed...
January 24, 2018: Zhonghua Xin Xue Guan Bing za Zhi
Michael Yapp, George Rennie, Michael P Hennessy, Michael Kalloniatis, Barbara Zangerl
PURPOSE: Optic nerve head (ONH) assessment and its interpretation in healthy patients and those with glaucoma remains a pivotal topic specifically considering rapid advancements in imaging technologies. We undertook a large-scale, mixed cohort, comparative study to assess the correlation of optic disc measurements between different imaging modalities and investigated the impact of patient and disc associated parameters. METHODS: ONH sizes were obtained from one randomly selected eye of each of 209 patients using stereophotography, confocal scanning laser ophthalmoscopy and two different optical coherence tomographers (OCT)...
2018: PloS One
Maged Alnawaiseh, Larissa Lahme, Viktoria Müller, André Rosentreter, Nicole Eter
PURPOSE: To evaluate the correlation between flow density, as measured by optical coherence tomography angiography (OCTA), and structural and functional parameters in patients with open-angle glaucoma. METHODS: Thirty-four eyes of 34 patients with open-angle glaucoma and 35 eyes of 35 healthy subjects were prospectively included in this study. OCTA was performed using RTVue XR Avanti with AngioVue. The macula was imaged with a 3 × 3 mm scan and the optic nerve head (ONH) with a 4...
January 13, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
Nimesh Patel, Anastas Pass, Sara Mason, Charles R Gibson, Christian Otto
Importance: After long-duration spaceflight, morphological changes in the optic nerve head (ONH) and surrounding tissues have been reported. Objective: To develop methods to quantify ONH and surrounding tissue changes using preflight and postflight optical coherence tomographic scans of the ONH region. Design, Setting, and Participants: Two separate analyses were done on retrospective data, with the first comparing a preflight group with a control group, followed by preflight to postflight analysis...
January 11, 2018: JAMA Ophthalmology
Andrew G Lee
No abstract text is available yet for this article.
January 11, 2018: JAMA Ophthalmology
Neeru Singla, Vishal Srivastava, Dalip Singh Mehta
Malaria is a life-threatening infectious blood disease affecting humans and other animals caused by parasitic protozoans belonging to the Plasmodium type especially in developing countries. The gold standard method for the detection of malaria is through the microscopic method of chemically treated blood smears. We developed an automated optical spatial coherence tomographic system using a machine learning approach for a fast identification of malaria cells. In this study, 28 samples (15 healthy, 13 malaria infected stages of red blood cells) were imaged by the developed system and 13 features were extracted...
January 3, 2018: Journal of Biophotonics
Chaoliang Chen, Victor X D Yang
Recently, parallel high A-line speed and wide field imaging for optical coherence tomography angiography (OCTA) has become more prevalent, resulting in a dramatic increase of data quantity which poses a challenge for real time imaging even for GPU in data processing. In this manuscript, we propose a new OCTA processing technique, Gabor optical coherence tomographic angiography (GOCTA), for label-free human retinal angiography imaging. In spectral domain optical coherence tomography (SDOCT), k-space resampling and Fourier transform (FFT) are required for the entire data set of interference fringes to calculate blood flow information in previous OCTA algorithms, which are computationally intensive...
December 1, 2017: Biomedical Optics Express
Santiago Jesús Camacho Freire, Antonio Enrique Gómez Menchero, Jessica Roa Garrido, Javier León Jiménez, Rosa Cardenal Piris, José Francisco Díaz Fernández
Spontaneous coronary artery dissection is a rare condition, and diagnosis and treatment are challenging among patients who present with acute coronary syndrome. Typically, the condition affects young females who have no underlying atherosclerotic disease. To date, few cases of bioresorbable scaffold implantation for the treatment of spontaneous coronary artery dissection have been reported. Therefore, we describe the cases of 4 patients whom we treated with scaffolds. We evaluated the long-term results by using intravascular ultrasound and optical coherence tomographic scanning...
December 2017: Texas Heart Institute Journal
Tomoka Ishida, Kei Morohoshi, Yayoi Takeuchi, Ryoko Soma, Minami Uchida, Kyoko Ohno-Matsui
Purpose: To report the swept-source optical coherence tomographic (OCT) findings in two eyes with choroidal metastases. Observations: Two patients with choroidal metastasis were studied. The metastasis was from a breast cancer in Case 1 and from a lung cancer in Case 2. In Case 1, swept-source OCT showed a highly reflective solid tumor with low optical reflective tissues that had replaced the choroidal tissue. Swept-source OCT was able to image the choroidal mass where other fundus imaging methods such as fluorescein angiography did not show the mass...
December 2017: American Journal of Ophthalmology Case Reports
Boya Lei, Ruiping Gu, Chen Jiang, Gezhi Xu
PURPOSE: To describe the characteristics of retinal telangiectasia in eyes with pathologic myopia. METHODS: The study included 10 patients (18 eyes) who were diagnosed with pathologic myopia combined with retinal telangiectasia. The patients visited our retinal clinic every 3 months. Nine eyes underwent vitrectomy for vision-threatening complications after diagnosis. All eyes underwent comprehensive ophthalmologic examinations including multimodal retinal imaging at presentation and at each follow-up...
December 8, 2017: Retina
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