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https://www.readbyqxmd.com/read/28910439/spectral-domain-optical-coherence-tomographic-angiography-in-children-with-amblyopia
#1
Marcela Lonngi, Federico G Velez, Irena Tsui, Juan Pablo Davila, Mansour Rahimi, Clarissa Chan, David Sarraf, Joseph L Demer, Stacy L Pineles
Importance: Amblyopia is the most common cause of visual impairment in childhood, with a prevalence of 1% to 4% in children in the United States. To date, no studies using noninvasive optical coherence tomographic angiography (OCTA) have measured blood flow in the retinal capillary layers in children with amblyopia. Objective: To evaluate the retinal and microvascular features using OCTA in children (<18 years) with amblyopia. Design, Setting, and Participants: This observational case-control study enrolled patients from September 1, 2016, through May 31, 2017, and was conducted from September 1, 2016, through June 30, 2017, at the Stein Eye Institute at UCLA (University of California, Los Angeles)...
September 14, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28910435/repeatability-and-reproducibility-of-superficial-macular-retinal-vessel-density-measurements-using-optical-coherence-tomography-angiography-en-face-images
#2
Jianqin Lei, Mary K Durbin, Yue Shi, Akihito Uji, Siva Balasubramanian, Elmira Baghdasaryan, Mayss Al-Sheikh, Srinivas R Sadda
Importance: The repeatability and reproducibility of quantitative metrics from optical coherence tomographic angiography (OCTA) must be assessed before these data can be confidently interpreted in clinical research and practice. Objective: To evaluate the repeatability and reproducibility of OCTA-derived retinal vascular quantitative metrics. Design, Setting and Participants: In this cross-sectional study, 21 healthy volunteers (42 eyes) and 22 patients with retinal disease (22 eyes), including 14 with age-related macular degeneration, 3 with epiretinal membrane, 2 with diabetic retinopathy, 2 with myopic macular degeneration, and 1 with retinal vein occlusion, were enrolled...
September 14, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28910424/the-arc-of-change-in-optical-coherence-tomographic-angiography-technology-progression-toward-greater-reliability
#3
Sean T Garrity, David Sarraf
No abstract text is available yet for this article.
September 14, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28903123/potential-effects-of-hormone-therapy-in-type-2-idiopathic-macular-telangiectasia
#4
Ute E K Wolf-Schnurrbusch, Irene Leung, Ferenc B Sallo, Traci E Clemons, Emily Y Chew, Alan C Bird, Tunde Peto
PURPOSE: To investigate the influence of hormone therapy with tamoxifen or estrogens on morphological changes in macular telangiectasia (MacTel) type 2 patients as revealed clinically in multiple imaging modalities. METHODS: Patients with a history of tamoxifen or estrogen use were selected from the cohort of the MacTel Study. A race-, age- and best-corrected visual acuity-matched group of MacTel participants not under hormone therapy served as the comparison group...
September 13, 2017: Ophthalmic Research
https://www.readbyqxmd.com/read/28902881/perioperative-factors-that-are-significantly-correlated-with-final-visual-acuity-in-eyes-after-successful-rhegmatogenous-retinal-detachment-surgery
#5
Misato Kobayashi, Takeshi Iwase, Kentaro Yamamoto, Eimei Ra, Kenta Murotani, Hiroko Terasaki
PURPOSE: To determine the perioperative factors that are significantly correlated with the final visual acuity following reattachment of a macula-off rhegmatogenous retinal detachment (RRD) by vitrectomy. METHODS: Twenty-nine eyes of 29 patients with a successfully reattached RRD by vitrectomy were retrospectively analyzed. Spectral-domain optical coherence tomographic images of the macular regions were used to measure the thicknesses of the retinal layers and the integrity of the microstructures of the photoreceptors at 2 weeks, 1, 2, 3, 6, 9, and 12 months following the vitrectomy...
2017: PloS One
https://www.readbyqxmd.com/read/28893795/serial-3-vessel-optical-coherence-tomography-and-intravascular-ultrasound-analysis-of-changing-morphologies-associated-with-lesion-progression-in-patients-with-stable-angina-pectoris
#6
Myong Hwa Yamamoto, Kennosuke Yamashita, Mitsuaki Matsumura, Akiko Fujino, Masaru Ishida, Seitarou Ebara, Toshitaka Okabe, Shigeo Saito, Koichi Hoshimoto, Kisaki Amemiya, Tadayuki Yakushiji, Naoei Isomura, Hiroshi Araki, Chiaki Obara, Thomas McAndrew, Masahiko Ochiai, Gary S Mintz, Akiko Maehara
BACKGROUND: Optical coherence tomographic (OCT) morphologies associated with lesion progression are not well studied. The aim of this study was to determine the morphological change for untreated lesion progression using both OCT and intravascular ultrasound (IVUS). METHODS AND RESULTS: We used baseline and 8-month follow-up 3-vessel OCT and IVUS to assess 127 nonculprit lesions (IVUS plaque burden ≥40%) in 45 patients with stable angina after target lesion treatment...
September 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28893770/serial-5-year-evaluation-of-side-branches-jailed-by-bioresorbable-vascular-scaffolds-using-3-dimensional-optical-coherence-tomography-insights-from-the-absorb-cohort-b-trial-a-clinical-evaluation-of-the-bioabsorbable-everolimus-eluting-coronary-stent-system
#7
Yoshinobu Onuma, Maik J Grundeken, Shimpei Nakatani, Taku Asano, Yohei Sotomi, Nicolas Foin, Jaryl Ng, Takayuki Okamura, Joanna J Wykrzykowska, Robbert J de Winter, Robert-Jan van Geuns, Jacques Koolen, Evald Christiansen, Robert Whitbourn, Dougal McClean, Pieter Smits, Stephan Windecker, John A Ormiston, Patrick W Serruys
BACKGROUND: The long-term fate of Absorb bioresorbable vascular scaffold (Abbott Vascular, Santa Clara, CA) struts jailing side branch ostia has not been clarified. We therefore evaluate serially (post-procedure and at 6 months, 1, 2, 3, and 5 years) the appearance and fate of jailed Absorb bioresorbable vascular scaffold struts. METHODS AND RESULTS: We performed 3-dimensional optical coherence tomographic analysis of the ABSORB Cohort B trial (A Clinical Evaluation of the Bioabsorbable Everolimus Eluting Coronary Stent System in the Treatment of Patients With De Novo Native Coronary Artery Lesions) up to 5 years using a novel, validated cut-plane analysis method...
September 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28878581/optical-coherence-tomographic-evaluation-of-hyperacute-bivalirudin-induced-coronary-stent-thrombosis
#8
Jorge L Peñalver, Wassim Shatila, Emerson Perin
Thrombus formation after stent deployment has been linked to the use of heparin and of antithrombotic agents, such as bivalirudin, during percutaneous coronary intervention. Fluoroscopy has been used to identify stent thrombosis, typically after patients become symptomatic. We describe our use of optical coherence tomography to diagnose and evaluate intraprocedural stent thrombosis in a 68-year-old man who was given bivalirudin just before a percutaneous coronary procedure. This imaging method enabled immediate therapeutic intervention...
August 2017: Texas Heart Institute Journal
https://www.readbyqxmd.com/read/28863408/polarization-sensitive-optical-coherence-tomographic-documentation-of-choroidal-melanin-loss-in-chronic-vogt-koyanagi-harada-disease
#9
Masahiro Miura, Shuichi Makita, Yoshiaki Yasuno, Rintaro Tsukahara, Yoshihiko Usui, Narsing A Rao, Yasushi Ikuno, Sato Uematsu, Tetsuya Agawa, Takuya Iwasaki, Hiroshi Goto
Purpose: Vogt-Koyanagi-Harada (VKH) disease is a systemic autoimmune disorder that affects organs with melanocytes. The sunset glow fundus (SGF) in VKH disease was evaluated with polarization-sensitive optical coherence tomography (PS-OCT). Methods: The study involved 28 eyes from 14 patients with chronic VKH disease, 21 eyes from 21 age-matched controls, and 22 eyes from 22 high-myopic patients with a tessellated fundus. VKH eyes were grouped into sunset or non-sunset groups on the basis of color fundus images...
September 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28851930/reproducibility-and-differences-in-area-of-foveal-avascular-zone-measured-by-three-different-optical-coherence-tomographic-angiography-instruments
#10
Hideki Shiihara, Taiji Sakamoto, Takehiro Yamashita, Naoko Kakiuchi, Hiroki Otsuka, Hiroto Terasaki, Shozo Sonoda
This study was performed to compare the area of the foveal avascular zone (FAZ-area) obtained by three optical coherence tomography angiography (OCTA) instruments. This was a cross-sectional, non-interventional study of twenty-seven healthy right eyes. The superficial and deep FAZ-area was measured manually with three OCTA instruments: Triton (Topcon), RS3000 (Nidek), and CIRRUS (Zeiss). The intra-rater, inter-rater, and inter-instrument correlation coefficients (CC) were assessed. The intra-rater and inter-rater CC were significantly high for the superficial and deep FAZ-areas (P < 0...
August 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28837721/visual-function-in-asymptomatic-patients-with-homozygous-sickle-cell-disease-and-temporal-macular-atrophy
#11
Gilles C Martin, Charlotte Dénier, Olivia Zambrowski, David Grévent, Lenaïc Bruère, Valentine Brousse, Mariane de Montalembert, Dominique Brémond-Gignac, Matthieu P Robert
Importance: Temporal macular involvement in sickle cell disease can now easily be detected by optical coherence tomography (OCT). However, while recent studies have demonstrated its high prevalence, little is known about its potential consequences on visual function. Objective: To assess the visual function of patients with sickle cell disease with no visual symptoms despite temporal macular atrophy. Design, Setting, and Participants: This retrospective case series included data collection and explorations made in a single referral center for sickle cell disease in 2016...
August 24, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28834919/a-case-of-neurofibromatosis-type-2-with-unusual-clinical-features
#12
Mohamma Zarei, Parisa Hamzeloui, Ramak Rooipoor, Masoud Aghsaei Fard
PURPOSE: To report a case of a neurofibromatosis Type 2 with unusual clinical features. METHODS: Observational clinical case report. RESULTS: A 22-year-old woman was referred with bilateral blurred vision and macular "scars." Ocular examination revealed bilateral posterior subcapsular and cortical cataract, optic disk swelling, hyperpigmented macular lesions, epiretinal membrane, and macular temporal dragging. Spectral-domain optical coherence tomographic imaging showed bilateral epiretinal membranes, peripapillary nerve fiber layer thickening, and vitreoretinal tractional bands...
August 21, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28831995/intravascular-imaging-in-coronary-artery-disease
#13
REVIEW
Gary S Mintz, Giulio Guagliumi
Although it is the method used by most interventional cardiologists to assess the severity of coronary artery disease and guide treatment, coronary angiography has many known limitations, particularly the fact that it is a lumenogram depicting foreshortened, shadowgraph, planar projections of the contrast-filled lumen rather than imaging the diseased vessel itself. Intravascular imaging-intravascular ultrasound and more recently optical coherence tomography-provide a tomographical or cross-sectional image of the coronary arteries...
August 19, 2017: Lancet
https://www.readbyqxmd.com/read/28816727/effect-of-time-on-scleral-lens-settling-and-change-in-corneal-clearance
#14
Heinz Otchere, Lyndon W Jones, Luigina Sorbara
SIGNIFICANCE: With the increase in the use of scleral contact lenses among practitioners, questions regarding lens settling are gradually gaining attention. This is because current studies support the notion that scleral lenses settle back over time. More research is needed to understand the exact cause and the factors that underpin such phenomenon. PURPOSE: The present study aims to assess the effect of time on topographic corneal clearance of three scleral contact lenses of varying sagittal depths...
September 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28745656/-effect-of-medicinal-treatment-on-epithelial-wound-healing-after-phacoemulsification
#15
E V Tomilova, M N Nemsitsveridze, I E Panova
AIM: to compare the dynamics of epithelial wound healing under two different post-op treatments in patients after uncomplicated phacoemulsification. MATERIAL AND METHODS: This prospective randomized clinical trial included 40 eyes of 40 patients aged 66.4±8.2 years who underwent uncomplicated phacoemulsification with flexible intraocular lens implantation through a 2.2-mm corneal incision. Patients were randomized to receive either dexamethasone 0.1% and diclofenac 0...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28738419/posterior-staphylomas-in-pathologic-myopia-imaged-by-widefield-optical-coherence-tomography
#16
Kosei Shinohara, Noriaki Shimada, Muka Moriyama, Takeshi Yoshida, Jost B Jonas, Nagahisa Yoshimura, Kyoko Ohno-Matsui
Purpose: To examine posterior staphylomas by widefield optical coherence tomography (WF-OCT) and three-dimensional magnetic resonance imaging (3D-MRI). Methods: Highly myopic patients (myopic refractive error >8.0 diopters or axial length >26.5 mm) who had previously undergone orbital 3D-MRI were examined by WF-OCT. Results: The study included 100 eyes of 57 patients with a mean age of 67.9 ± 10.7 years (range, 44-85 years) and mean axial length of 30...
July 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28727836/the-disc-damage-likelihood-scale-diagnostic-accuracy-and-correlations-with-cup-to-disc-ratio-structural-tests-and-standard-automated-perimetry
#17
Andrea C Kara-José, Luiz Alberto S Melo, Bruno L B Esporcatte, Angelica T N H Endo, Mauro Toledo Leite, Ivan Maynart Tavares
Our objective was to compare the diagnostic accuracies of and to determine the correlations between the disc damage likelihood scale (DDLS) and anatomical and functional tests used for glaucoma detection. A total of 54 healthy subjects (54 eyes) and 47 primary open-angle glaucoma patients (47 eyes) were included in this cross-sectional observational study. DDLS scores and cup-to-disc (C/D) ratios were evaluated. Subjects underwent standard automated perimetry (SAP), optic disc and retinal nerve fiber layer (RNFL) imaging with time and spectral-domain optical coherence tomography (TD and SD-OCT), Heidelberg Retina Tomograph (HRT II), and scanning laser polarimetry (GDx-VCC)...
2017: PloS One
https://www.readbyqxmd.com/read/28723848/progression-of-macular-atrophy-in-eyes-with-type-1-neovascularization-and-age-related-macular-degeneration-receiving-long-term-intravitreal-anti-vascular-endothelial-growth-factor-therapy-an-optical-coherence-tomographic-angiography-analysis
#18
Joseph G Christenbury, Nopasak Phasukkijwatana, Fatimah Gilani, K Baily Freund, SriniVas Sadda, David Sarraf
PURPOSE: To evaluate the size and location of macular atrophy in eyes with Type-1 neovascularization (NV) and age-related macular degeneration receiving chronic intravitreal anti-vascular endothelial growth factor therapy. METHODS: A retrospective review of a case series of 27 eyes with Type-1 NV and retinal pigment epithelial detachment (PED) having a minimum of 12 months follow-up was performed. Demographic information and visual acuity at baseline and the final follow-up were collected...
July 18, 2017: Retina
https://www.readbyqxmd.com/read/28707379/three-and-6-month-optical-coherence-tomographic-surveillance-following-percutaneous-coronary-intervention-with-the-angiolite%C3%A2-drug-eluting-stent-the-anchor-study
#19
Rishi Puri, Imanol Otaegui, Manel Sabaté, Antonio Serra-Peñaranda, Marti Puigfel, Armando Perez de Prado, Luis Nombela-Franco, Jose M de la Torre Hernandez, Rosario Ortas Nadal, Andres Iniguez-Romo, Gustavo Jiménez, Felipe Fernandez-Vazquez, Carlos Cuellas-Ramon, Nieves Gonzalo, Victor Alfonso Jiménez Diaz, Lluis Duocastella, Maria Molina, Marc Amoros, Isabel Perez, Alberto Barria Perez, Emilie Pelletier Beaumont, Stephen J Nicholls, Bruno Garcia Del Blanco, Josep Rodés-Cabau
BACKGROUND: Pre-clinical results of a novel open-cell, thin strut, durable polymer, laser cut cobalt chromium sirolimus-eluting stent (Angiolite) were promising. Using quantitative optical coherence tomographic (OCT) analyses, we explored the healing characteristics of the Angiolite DES system at 3- and 6-months post implantation. METHODS: A total of 103 patients with de novo coronary lesions underwent percutaneous coronary intervention with the Angiolite DES and were randomized 1:3 into two cohorts for angiographic and OCT follow-up, with 28 and 70 patients returning for 3- or 6-month post-PCI surveillance, respectively...
July 14, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28687852/optical-coherence-tomographic-imaging-of-posterior-episclera-and-tenon-s-capsule
#20
Kyoko Ohno-Matsui, Yuxin Fang, Kei Morohoshi, Jost B Jonas
Purpose: To investigate structural features of the posterior episclera and Tenon's capsule in patients with high myopia. Methods: This hospital-based observational study included highly myopic eyes (myopic refractive error > -8 diopters or axial length ≥26.5 mm) in which the posterior sclera in its full thickness could be visualized on swept-source optical coherence tomography (OCT) images in all 12 radial scans centered on the fovea. We assessed the posterior episclera and Tenon's capsule...
July 1, 2017: Investigative Ophthalmology & Visual Science
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