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optical coherence tomograph

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https://www.readbyqxmd.com/read/28093287/diagnostic-accuracy-of-imaging-devices-in-glaucoma-a-meta-analysis
#1
REVIEW
Monica Fallon, Oliver Valero, Marta Pazos, Alfonso Antón
Imaging devices such as the Heidelberg Retinal Tomograph (HRT3), scanning laser polarimetry (GDx), and optical coherence tomography (OCT), play an important role in glaucoma diagnosis. A systematic search for evidence-based data was performed for prospective studies evaluating the diagnostic accuracy of HRT3, GDx and OCT. The diagnostic odds ratio (DOR) was calculated. To compare the accuracy among instruments and parameters, a meta-analysis considering the hierarchical summary receiver operating characteristic (H-SROC) model was performed...
January 13, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28079755/macular-pigment-distribution-responses-to-high-dose-zeaxanthin-supplementation-in-patients-with-macular-telangiectasia-type-2
#2
Rene Y Choi, Aruna Gorusupudi, Kimberley Wegner, Mohsen Sharifzadeh, Werner Gellermann, Paul S Bernstein
PURPOSE: To analyze macular pigment (MP) amount and distribution in patients with macular telangiectasia Type 2 receiving oral zeaxanthin supplementation in a randomized, open-label, interventional trial. METHODS: Eight macular telangiectasia Type 2 patients were randomized to 10 mg or 20 mg of zeaxanthin per day. At each visit, best-corrected visual acuity, contrast sensitivity, fundus biomicroscopy, color fundus photography, autofluorescence imaging, optical coherence tomography, and serum carotenoid levels were tested...
January 10, 2017: Retina
https://www.readbyqxmd.com/read/28079690/noncontact-evaluation-of-corneal-grafts-swept-source-fourier-domain-oct-versus-high-resolution-scheimpflug-imaging
#3
Eszter Szalai, Gábor Németh, Ziad Hassan, László Módis
PURPOSE: To study the reliability and repeatability of anterior segment measurements in patients who underwent penetrating keratoplasty with swept light source Fourier domain anterior segment optical coherence tomography (SS-OCT) in comparison with a high-resolution Scheimpflug camera. METHODS: Keratometry (K) and elevation data of the anterior and posterior corneal surfaces, central corneal thickness, and anterior chamber depth were determined in 56 postkeratoplasty eyes (mean age: 59...
January 11, 2017: Cornea
https://www.readbyqxmd.com/read/28079655/microarchitecture-of-schlemm-canal-before-and-after-selective-laser-trabeculoplasty-in-enhanced-depth-imaging-optical-coherence-tomography
#4
Alon Skaat, Michael S Rosman, Jason L Chien, Mark P Ghassibi, Jeffrey M Liebmann, Robert Ritch, Sung Chul Park
PURPOSE: To characterize the in vivo effect of selective laser trabeculoplasty (SLT) on the Schlemm canal (SC) in eyes with primary open-angle glaucoma (POAG). MATERIALS AND METHODS: Eighty-one serial horizontal enhanced depth imaging optical coherence tomograph B-scans (interval between B-scans, ∼35 μm) of the nasal corneoscleral limbus were obtained before and 4 weeks after SLT. Fifty B-scans in the overlapping regions before and after SLT were selected for analysis based on the structures of aqueous and blood vessels as landmarks...
January 10, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28027273/oxygen-tension-beneath-scleral-lenses-of-different-clearances
#5
Claude J Giasson, Jeanne Morency, Marc Melillo, Langis Michaud
PURPOSE: To evaluate the relative partial pressure in oxygen (pO2) at the corneal surface under Boston XO2 scleral lenses (SL) fitted with targeted clearances of 200 and 400 μm (SL200 and SL400). METHODS: During this prospective study, the right eyes of eight normal subjects were fitted with SL200 and SL400. Clearance, validated after 5 minutes of wear with an optical coherence tomograph, was used with lens thicknesses to calculate transmissibility and estimate pO2...
December 23, 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28005581/retinal-deep-capillary-plexus-ischemia-in-a-case-with-antiphospholipid-syndrome
#6
Serra Arf, Isil Sayman Muslubas, Mumin Hocaoglu, Murat Karacorlu
PURPOSE: To report visualization of a case of retinal deep capillary plexus ischemia with antiphospholipid syndrome. METHODS: A 53-year-old woman was referred with a 1-week history of sudden onset of decreased vision in the right eye. Her symptoms were evaluated by clinical examination, infrared reflectance, fundus autofluorescence, fluorescein angiography, spectral-domain optical coherence tomography, microperimetry, and multifocal electroretinography. RESULTS: The patient's visual acuity on presentation was 0...
September 30, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27997513/semiautomated-quantitative-approach-to-characterize-treatment-response-in-neovascular-age-related-macular-degeneration-a-real-world-study
#7
Philipp K Roberts, Peter L Nesper, Manjot K Gill, Amani A Fawzi
PURPOSE: To perform a quantitative study of the vascular microstructure in actively treated choroidal neovascularization by optical coherence tomographic angiography. METHODS: Patients undergoing individualized anti-vascular endothelial growth factor therapy of minimum 12 months duration were included in this cross-sectional observational study and imaged using optical coherence tomographic angiography. En face optical coherence tomographic angiography images were analyzed for quantitative features, such as junction density, vessel length, and lacunarity using validated software (Angiotool)...
December 16, 2016: Retina
https://www.readbyqxmd.com/read/27992524/optical-coherence-tomographic-features-and-prognosis-of-pneumatic-displacement-for-submacular-hemorrhage
#8
Kunho Bae, Ga Eun Cho, Je Moon Yoon, Se Woong Kang
PURPOSE: To identify prognostic factors, including optical coherence tomographic features, of visual outcome in exudative age-related macular degeneration with submacular hemorrhage treated with pneumatic displacement. METHODS: This retrospective interventional case series included 37 eyes with exudative age-related macular degeneration and submacular hemorrhage, all of which underwent pneumatic displacement. The best-corrected visual acuity (BCVA) was measured at diagnosis and at 3 and 6 months after treatment...
2016: PloS One
https://www.readbyqxmd.com/read/27974321/changes-of-choroidal-structure-after-intravitreal-aflibercept-therapy-for-polypoidal-choroidal-vasculopathy
#9
Erina Daizumoto, Yoshinori Mitamura, Hiroki Sano, Kei Akaiwa, Masanori Niki, Chihiro Yamanaka, Takamasa Kinoshita, Mariko Egawa, Shozo Sonoda, Taiji Sakamoto
AIMS: To quantify the changes of the choroidal structure in the enhanced depth imaging optical coherence tomographic (EDI-OCT) images after intravitreal aflibercept (IVA) injections for polypoidal choroidal vasculopathy (PCV). METHODS: Retrospective, observational case series. Forty eyes of 40 treatment-naive patients who underwent IVA for PCV were examined by EDI-OCT before, and 3 months and 12 months after IVA. The EDI-OCT images were binarised by ImageJ software...
January 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27973598/effects-of-exercise-on-the-structure-and-circulation-of-choroid-in-normal-eyes
#10
Takamasa Kinoshita, Junya Mori, Natsuki Okuda, Hiroko Imaizumi, Masanori Iwasaki, Miho Shimizu, Hirotomo Miyamoto, Kei Akaiwa, Kentaro Semba, Shozo Sonoda, Taiji Sakamoto, Yoshinori Mitamura
AIMS: To determine the effects of dynamic exercise on the circulation and the luminal and stromal areas of the choroid in normal eyes. METHODS: This was a prospective interventional study of 38 eyes of 38 normal subjects enrolled by invitation. The systolic and diastolic blood pressures, heart rate, intraocularpressure, mean ocular perfusion pressure (MOPP), choroidal blood velocity, and enhanced depth imaging optical coherence tomographic (EDI-OCT) images were recorded before, and immediately after mild dynamic exercise...
2016: PloS One
https://www.readbyqxmd.com/read/27965297/clinical-impact-of-suboptimal-stenting-and-residual-intrastent-plaque-thrombus-protrusion-in-patients-with-acute-coronary-syndrome-the-cli-opci-acs-substudy-centro-per-la-lotta-contro-l-infarto-optimization-of-percutaneous-coronary-intervention-in-acute-coronary
#11
Francesco Prati, Enrico Romagnoli, Laura Gatto, Alessio La Manna, Francesco Burzotta, Ugo Limbruno, Francesco Versaci, Franco Fabbiocchi, Alessandro Di Giorgio, Valeria Marco, Vito Ramazzotti, Luca Di Vito, Carlo Trani, Italo Porto, Alberto Boi, Luigi Tavazzi, Gary S Mintz
BACKGROUND: Clinical consequences of optical coherence tomographic (OCT) high-definition visualization of plaque/stent structures in acute patients remain undefined. In this retrospective substudy, we assessed the prognostic impact of postprocedural culprit lesion OCT findings in patients with acute coronary syndrome undergoing percutaneous coronary intervention. METHODS AND RESULTS: In the CLI-OPCI (Centro per la Lotta Contro L'Infarto-Optimization of Percutaneous Coronary Intervention) database collecting cases from 5 independent OCT-experienced centers, we retrospectively analyzed postprocedural OCT findings in acute coronary syndrome patients and explored its possible impact (specifically that of residual intrastent plaque/thrombus protrusion) on outcome...
December 2016: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27942202/the-measurement-repeatability-using-different-partition-methods-of-intraretinal-tomographic-thickness-maps-in-healthy-human-subjects
#12
Jia Tan, Ye Yang, Hong Jiang, Che Liu, Zhihong Deng, Byron L Lam, Liang Hu, Jonathan Oakley, Jianhua Wang
PURPOSE: To determine the repeatability and profiles with different partition methods in intraretinal thickness layers in healthy human subjects, using optical coherence tomography (OCT). METHODS: A custom-built ultrahigh-resolution OCT was used to acquire three-dimensional volume of the macula in 20 healthy subjects. The dataset was acquired twice using the macular cube 512×128 protocol in an area of 6×6 mm(2) centered on the fovea. Commercially available segmentation software (Orion™) was used to segment the dataset into thickness maps of six intraretinal layers...
2016: Clinical Ophthalmology
https://www.readbyqxmd.com/read/27936241/correction-intrasession-and-between-visit-variability-of-sector-peripapillary-angioflow-vessel-density-values-measured-with-the-angiovue-optical-coherence-tomograph-in-different-retinal-layers-in-ocular-hypertension-and-glaucoma
#13
https://www.readbyqxmd.com/read/27935604/ocular-characteristics-associated-with-the-location-of-focal-lamina-cribrosa-defects-in-open-angle-glaucoma-patients
#14
H-Yl Park, Y S Hwang, C K Park
PurposeTo investigate the clinical characteristics according to the location of focal lamina cribrosa (LC) defects and its associated ocular features.Patients and methodsA total of 139 open-angle glaucoma patients underwent Spectralis optical coherence tomography (OCT) with enhanced depth imaging. Alterations in the contour of the LC were investigated to find focal LC defects. The location of the visible LC defect from the neural canal wall (far-peripheral and mid-peripheral) and clock-hour position (superotemporal, temporal and inferotemporal) were classified...
December 9, 2016: Eye
https://www.readbyqxmd.com/read/27928393/the-optical-coherence-tomographic-profile-of-leber-hereditary-optic-neuropathy
#15
Thomas R Hedges, Marisa Gobuty, Richard A Manfready, Natalie Erlich-Malona, Caitlin Monaco, Carlos E Mendoza-Santiesteban
The objective of this study was to describe the changes in the retinal ganglion cell complex (GCC) relative to the retinal nerve fibre layer (RNFL) over time in Leber hereditary optic neuropathy (LHON) patients. Average RNFL and GCC thickness was measured in seven patients in the early acute (123, 68.4 μm), late acute (113.5, 57.4 μm), and chronic (72.7, 50.8 μm) phases. Patients showed thinning of the GCC with RNFL swelling in the early acute phase. GCC thinning became severe within weeks and persisted...
June 2016: Neuro-ophthalmology
https://www.readbyqxmd.com/read/27913440/optical-coherence-tomographic-angiography-of-choroidal-neovascularization-ill-defined-with-fluorescein-angiography
#16
Mehrdad Malihi, Yali Jia, Simon S Gao, Christina Flaxel, Andreas K Lauer, Thomas Hwang, David J Wilson, David Huang, Steven T Bailey
PURPOSE: To evaluate the morphological structure of ill-defined choroidal neovascularisation (CNV) with traditional fluorescein angiography (FA) compared with optical coherence tomographic angiography (OCTA). METHODS: A retrospective case series study of 11 eyes with ill-defined CNV on FA was performed. Eyes were scanned with commercially available spectral-domain optical coherence tomography (OCT) (70 000 A-scans/s). The split-spectrum amplitude-decorrelation angiography (SSADA) algorithm was used to distinguish blood flow from static tissue...
January 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27911421/-analysis-of-changes-in-central-macular-thickness-based-on-optical-coherence-tomography-angiography-findings-in-retinal-vein-occlusion
#17
M V Budzinskaya, A V Shelankova, M A Mikhailova, A A Plyukhova, N M Nurieva, A V Fomin
AIM: To investigate the relationship between OCT angiography measurements and central fundus changes in patients with retinal vein occlusion (RVO). MATERIAL AND METHODS: The study enrolled 21 RVO patients aged from 55 to 86 years (69.9±2.28 years), including 8 patients with ischemic central RVO (I-CRVO; 73.6±3.4 years on average) and 13 patients with branch RVO (BRVO; 67.6±3.0 years on average). Of the latter, 8 cases were ischemic (I-BRVO) and 5 non-ischemic (NI-BRVO)...
2016: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/27910470/stokes-doppler-coherence-imaging-for-iter-boundary-tomography
#18
J Howard, M Kocan, S Lisgo, R Reichle
An optical coherence imaging system is presently being designed for impurity transport studies and other applications on ITER. The wide variation in magnetic field strength and pitch angle (assumed known) across the field of view generates additional Zeeman-polarization-weighting information that can improve the reliability of tomographic reconstructions. Because background reflected light will be somewhat depolarized analysis of only the polarized fraction may be enough to provide a level of background suppression...
November 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27896899/characterization-of-a-novel-form-of-progressive-retinal-atrophy-in-whippet-dogs-a-clinical-electroretinographic-and-breeding-study
#19
André Tavares Somma, Juan Carlos Duque Moreno, Mario Teruo Sato, Blanche Dreher Rodrigues, Marianna Bacellar-Galdino, Laurence Mireille Occelli, Simon Michael Petersen-Jones, Fabiano Montiani-Ferreira
OBJECTIVE: To describe a form of progressive retinal atrophy (PRA) in Whippets including clinical, electroretinographic, optical coherence tomographic changes and pedigree analysis. ANIMALS STUDIED: Client-owned Whippet dogs (n = 51) living in Brazil. PROCEDURES: All animals were submitted for routine ophthalmic screening for presumed inherited ocular disease, which included the following: visual tests, such as obstacle course tests, in scotopic and photopic conditions, cotton ball test, dazzle reflex, ocular fundus evaluation by indirect ophthalmoscopy followed by fundus photography...
November 29, 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/27889345/histopathological-differential-diagnosis-of%C3%A2-optical-coherence-tomographic-image%C3%A2-interpretation-after-stenting
#20
Christoph Lutter, Hiroyoshi Mori, Kazuyuki Yahagi, Elena Ladich, Michael Joner, Robert Kutys, David Fowler, Maria Romero, Jagat Narula, Renu Virmani, Aloke V Finn
OBJECTIVES: The aim of this study was to identify histological features that correlate with terms commonly used to describe optical coherence tomographic (OCT) and optical frequency-domain imaging (OFDI) images of stented vessels, by means of a histopathological validation study using stented human coronary arteries. BACKGROUND: OCT imaging and OFDI are used to evaluate vascular responses to stent implantation. Descriptive terms such as "peristrut low attenuation" and "heterogeneous" have been used to describe neointimal characteristics that may have clinical relevance...
December 26, 2016: JACC. Cardiovascular Interventions
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