Read by QxMD icon Read


Harun Ilhan, Anna Goritschan, Philipp Paprottka, Tobias F Jakobs, Wolfgang P Fendler, Andrei Todica, Peter Bartenstein, Marcus Hacker, Alexander R Haug
UNLABELLED: This study analyzed the predictive value of (99m)Tc-labeled macroaggregated albumin ((99m)Tc-MAA) SPECT for (90)Y-labeled resin microsphere therapy (radioembolization) by comparing uptake on pretherapeutic (99m)Tc-MAA SPECT with uptake on posttherapeutic (90)Y-bremsstrahlung SPECT. METHODS: We included 502 patients (55% male; mean age ± SD, 62 ± 11 y) who underwent radioembolization between 2005 and 2013 because of primary or secondary liver malignancies (colorectal cancer [n = 195, 38...
November 2015: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
Yehuda Ringel, Nitsan Maharshak, Tamar Ringel-Kulka, Elizabeth Ashley Wolber, R Balfour Sartor, Ian M Carroll
BACKGROUND: The intestinal microbiota is associated with human health and diseases. The luminal microbiota (LM) and the mucosal-associated microbiota (MAM) are 2 distinct ecosystems with different metabolic and immunological functions. AIM: To characterize the intestinal LM and MAM in humans using high throughput sequencing of the 16S rRNA gene. METHODS: Fresh fecal samples and distal colonic mucosal biopsies collected from 24 healthy subjects before (fecal) and during (mucosa) a flexible sigmoidoscopy of an un-prepared bowel...
2015: Gut Microbes
Harun Ilhan, Anna Goritschan, Phillip Paprottka, Tobias F Jakobs, Wolfgang P Fendler, Peter Bartenstein, Marcus Hacker, Alexander R Haug
UNLABELLED: The aim of this study was to evaluate the (99m)Tc-macroaggregated albumin ((99m)Tc-MAA) uptake of primary and secondary liver tumors in a large patient cohort before (90)Y radioembolization. METHODS: We included 502 patients during the years 2005-2013 (55% male; mean age, 62 ± 11 y), who were examined with (99m)Tc-MAA SPECT or SPECT/CT before planned radioembolization. The patients had colorectal cancer (CRC; n = 195, 38.8%), neuroendocrine tumors (NET; n = 77, 15...
March 2015: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
A Awaiz, F Rahman, M B Hossain, R M Yunus, S Khan, B Memon, M A Memon
CONTEXT: The utility of laparoscopic repair in the treatment of incisional hernia repair is still contentious. OBJECTIVES: The aim was to conduct a meta-analysis of RCTs investigating the surgical and postsurgical outcomes of elective incisional hernia by open versus laparoscopic method. DATA SOURCES: A search of PubMed, Medline, Embase, Science Citation Index, Current Contents, and the Cochrane Central Register of Controlled Trials published between January 1993 and September 2013 was performed using medical subject headings (MESH) "hernia," "incisional," "abdominal," "randomized/randomised controlled trial," "abdominal wall hernia," "laparoscopic repair," "open repair", "human" and "English"...
June 2015: Hernia: the Journal of Hernias and Abdominal Wall Surgery
Tae-Yong Ha, Shin Hwang, Chul-Soo Ahn, Ki-Hun Kim, Young-Joo Lee, Deok-Bog Moon, Gi-Won Song, Dong-Hwan Jung, Gil-Chun Park, Sung-Gyu Lee
BACKGROUND: This study analyzed the patient survival outcomes following the resection of hepatocellular carcinoma (HCC) metachronous adrenal metastasis (MAM) in patients who had undergone liver resection or liver transplantation (LT). METHODS: Clinical results were analyzed retrospectively in 26 patients with MAM-HCC who underwent adrenalectomy. RESULTS: The mean interval between initial surgery and adrenalectomy was significantly shorter in the resection group than in the LT group (18...
2014: Digestive Surgery
J Keerthiwansa, S Gajealan, S Sivaraja, K Y Subashini
We conducted a cross sectional descriptive study to describe the factors associated with the degree of malnutrition among hospitalised malnourished children in General Hospital, Vavuniya. All hospitalised children from January to June 2012 (n=1210) were screened and the nutritional status assessed using WHO growth standards for weight for height/length. A total of 179 children with moderate acute malnutrition (MAM) (14.8%) and 105 children with severe acute malnutrition (SAM) (8.7%) were detected during this period...
December 2014: Ceylon Medical Journal
Hui-Chi Hung, Ya-Hsin Hsiao, Po-Wu Gean
BACKGROUND: It is known that neurogenesis occurs throughout the life mostly in the subgranular zone of the hippocampus and the subventricular zone of the lateral ventricle. We investigated whether neurogenesis occurred in the amygdala and its function in fear memory formation. METHODS: For detection of newborn neurons, mice were injected intraperitoneally with 5-bromo-2'-deoxyuridine (BrdU) 2h before receiving 15 tone-footshock pairings, and newborn neurons were analyzed 14 and 42 days after training...
December 13, 2014: International Journal of Neuropsychopharmacology
Venkataswarup Tiriveedhi, Natalia Tucker, John Herndon, Lijin Li, Mark Sturmoski, Matthew Ellis, Cynthia Ma, Michael Naughton, A Craig Lockhart, Feng Gao, Timothy Fleming, Peter Goedegebuure, Thalachallour Mohanakumar, William E Gillanders
PURPOSE: Mammaglobin-A (MAM-A) is overexpressed in 40% to 80% of primary breast cancers. We initiated a phase I clinical trial of a MAM-A DNA vaccine to evaluate its safety and biologic efficacy. EXPERIMENTAL DESIGN: Patients with breast cancer with stable metastatic disease were eligible for enrollment. Safety was monitored with clinical and laboratory assessments. The CD8 T-cell response was measured by ELISPOT, flow cytometry, and cytotoxicity assays. Progression-free survival (PFS) was described using the Kaplan-Meier product limit estimator...
December 1, 2014: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
Sebastian Kolinko, Michael Richter, Frank-Oliver Glöckner, Andreas Brachmann, Dirk Schüler
For magnetic orientation, magnetotactic bacteria biosynthesize magnetosomes, which consist of membrane-enveloped magnetic nanocrystals of either magnetite (Fe3 O4 ) or greigite (Fe3 S4 ). While magnetite formation is increasingly well understood, much less is known about the genetic control of greigite biomineralization. Recently, two related yet distinct sets of magnetosome genes were discovered in a cultivated magnetotactic deltaproteobacterium capable of synthesizing either magnetite or greigite, or both minerals...
October 2014: Environmental Microbiology Reports
Laetitia Nikièma, Lieven Huybregts, Patrick Kolsteren, Hermann Lanou, Simon Tiendrebeogo, Kimberley Bouckaert, Séni Kouanda, Blaise Sondo, Dominique Roberfroid
BACKGROUND: Management of moderate acute malnutrition (MAM) is, currently, focused on food supplementation approaches. However, the sustainability of these strategies remains weak in low- and middle-income countries. In food-secure settings, an educational/behavioral intervention could be an alternative for improving MAM management. OBJECTIVE: This study compared the effectiveness of weekly context-appropriate child-centered counseling (CCC), with an improved corn-soy blend [corn-soy blend with added micronutrients (CSB++)] or a locally produced ready-to-use supplementary food (RUSF), in treating MAM through first-line rural health services...
July 2014: American Journal of Clinical Nutrition
Min Kang, Ying Zhao, Yuan Huang, Jiayuan Li, Lianhua Liu, Hui Li
OBJECTIVE: To evaluate the accuracy and direct medical cost of different screening modalities of physical examination (PE), mammography (MAM), and high-frequency ultrasonography (US) for breast cancer among Chinese women. METHODS: This study was designed as a blindly carried outcom parative parallel screening trial for breast cancer among Chinese women aged 35 years or older. Physical examination was conducted with the subjects in the first round of breast cancer screening...
March 2014: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
Anne Marie Chomat, Noel W Solomons, Gabriela Montenegro, Caitlin Crowley, Odilia I Bermudez
OBJECTIVE: To obtain background information about maternal health and health-seeking behaviors among indigenous mothers living in rural Mam-Mayan communities of Quetzaltenango, Guatemala. METHODS: A cross-sectional analysis of 100 pregnant and breastfeeding women in four communities was performed to determine prevalence and determinants of service utilization. RESULTS: Extreme poverty, poor education, and poor access to basic resources were prevalent...
February 2014: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
A Gottås, F Boix, E L Øiestad, V Vindenes, J Mørland
After injection, heroin is rapidly metabolized to 6-monoacetylmorphine (6-MAM) and further to morphine. As morphine has been shown to increase striatal dopamine, whereas 6-MAM has not been studied in this respect, we gave i.v. injections of 3 μmol 6-MAM, morphine or heroin to rats. Opioids were measured in blood, and dopamine and opioids in microdialysate from brain striatal extracellular fluid (ECF), by UPLC-MS/MS. After 6-MAM injection, 6-MAM ECF concentrations increased rapidly, and reached Cmax of 4.4 μM after 8 min...
September 2014: International Journal of Neuropsychopharmacology
Lindsey M Lenters, Kerri Wazny, Patrick Webb, Tahmeed Ahmed, Zulfiqar A Bhutta
BACKGROUND: Globally, moderate acute malnutrition (MAM) and severe acute malnutrition (SAM) affect approximately 52 million children under five. This systematic review evaluates the effectiveness of interventions for SAM including the World Health Organization (WHO) protocol for inpatient management and community-based management with ready-to-use-therapeutic food (RUTF), as well as interventions for MAM in children under five years in low- and middle-income countries. METHODS: We systematically searched the literature and included 14 studies in the meta-analysis...
2013: BMC Public Health
Mei-chen Feng, Lu-jie Xiao, Mei-jun Zhang, Wu-de Yang, Guang-wei Ding
In this study, relationships between normalized difference vegetation index (NDVI) and plant (winter wheat) nitrogen content (PNC) and between PNC and grain protein content (GPC) were investigated using multi-temporal moderate-resolution imaging spectroradiometer (MODIS) data at the different stages of winter wheat in Linfen (Shanxi, P. R. China). The anticipating model for GPC of winter wheat was also established by the approach of NDVI at the different stages of winter wheat. The results showed that the spectrum models of PNC passed F test...
2014: PloS One
Danilo Barral Araujo, Elisângela de Jesus Campos, Marcos André Matos Oliveira, Max José Pimenta Lima, Gabriela Botelho Martins, Roberto Paulo Correia Araujo
AIM: Realize the surgery of sinus lifting floor to allow the installation of osseointegrated implants for oral rehabilitation, with the combination of different biomaterials, autogenous bone and lyophilized bovine bone. BACKGROUND: Oral rehabilitation using the installation of osseointegrated implants is an alternative surgical approach that results in the satisfactory form, function and esthetics of the dental units. CASE REPORT: After clinical, dental and laboratory assessment, a 47-year-old female patient underwent full maxillary oral rehabilitation involving the installation of osseointegrated implants to allow her to meet the physiological demands of occlusion and mastication...
May 2013: Journal of Contemporary Dental Practice
Waheeba A Al-Amrani, P E Lim, C E Seng, W S Wan Ngah
Bioregeneration of mono-amine modified silica gel (MAMS) adsorbent loaded with Acid Orange 7 (AO7), Acid Yellow 9 (AY9) and Acid Red 14 (AR14), respectively, was investigated under two different operational conditions, namely absence/presence of sucrose/bacto-peptone as the co-substrate and different biomass acclimation concentrations. The results revealed that the AY9- and AR14-loaded MAMS adsorbents could almost be completely bioregenerated but only in the presence of co-substrate whereas the bioregeneration of AO7-loaded MAMS could achieve up to 71% in the absence of the co-substrate...
September 2013: Bioresource Technology
Marzia Lazzerini, Laura Rubert, Paola Pani
BACKGROUND: Moderate acute malnutrition, also called moderate wasting, affects around 10% of children under five years of age in low- and middle-income countries. There are different approaches to addressing malnutrition with prepared foods in these settings; for example, providing lipid-based nutrient supplements or blended foods, either a full daily dose or in a low dose as a complement to the usual diet. There is no definitive consensus on the most effective way to treat children with moderate acute malnutrition...
2013: Cochrane Database of Systematic Reviews
Ida Annunziata, Annette Patterson, Alessandra d'Azzo
Intracellular organelles are highly dynamic structures with varying shape and composition, which are subjected to cell-specific intrinsic and extrinsic cues. Their membranes are often juxtaposed at defined contact sites, which become hubs for the exchange of signaling molecules and membrane components(1,2,3,4). The inter-organellar membrane microdomains that are formed between the endoplasmic reticulum (ER) and the mitochondria at the opening of the IP3-sensitive Ca(2+) channel are known as the mitochondria associated-ER membranes or MAMs(4,5,6)...
2013: Journal of Visualized Experiments: JoVE
M J van Det, W J H J Meijerink, C Hoff, B Middel, J P E N Pierie
BACKGROUND: INtraoperative Video Enhanced Surgical procedure Training (INVEST) is a new training method designed to improve the transition from basic skills training in a skills lab to procedural training in the operating theater. Traditionally, the master-apprentice model (MAM) is used for procedural training in the operating theater, but this model lacks uniformity and efficiency at the beginning of the learning curve. This study was designed to investigate the effectiveness and efficiency of INVEST compared to MAM...
August 2013: Surgical Endoscopy
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"