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https://www.readbyqxmd.com/read/28979624/-central-neurocytomas-clinical-and-radiopathological-correlations-about-12-cases
#1
Fay├žal Abbad, Souad Sellami, Fe Hazmiri, Najat El Idriss Ganouni, Said Ait Benali, Mouna Khouchani, Hanane Rais
Central neurocytomas are defined as neoplasms composed of round, uniform cells, with neural immunophenotypic profile and low proliferation index. They account for 0.5% of intracranial tumors. They usually occur near the foramen of Monro and can cause obstructive hydrocephaly. We conducted a retrospective data collection from records of 12 patients with central neurocytomas in the Anatomopathological Laboratory at the Mohammed VI University Hospital, Marrakech, between January 2006 and June 2015. This study aimed to report and describe the radiopathological features of this rare histologic type...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28958923/clinical-features-treatment-and-long-term-outcomes-of-central-neurocytoma-a-20-year-experience-at-a-single-center
#2
Mengmeng Wang, Peizhi Zhou, Shizhen Zhang, Xueyou Liu, Liang Lv, Zeming Wang, Feng Ye, Xiang Wang, Shu Jiang
OBJECTIVE: Central neurocytoma (CN) is a rare central nervous system tumor whose optimal management strategy remains controversial due to their rarity. A thorough research of detail information of CN is very necessary to establish optimal management strategies. The purpose of this study was to demonstrate the clinical features, treatments and long-term clinical outcomes of CN. METHODS: A total of 63 cases with CN were surgically treated between 1995 and 2016 at West China Hospital...
September 25, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28900829/clinical-radiological-pathological-and-prognostic-aspects-of-intraventricular-oligodendroglioma-comparison-with-central-neurocytoma
#3
Xiang Xiao, Jun Zhou, Jun Wang, Lei Yang, Chunhong Wang, Yikai Xu, Yuankui Wu
Studies comparing intraventricular oligodendroglioma (IVO) and central neurocytoma (CN) in terms of their clinical, radiological and pathological features are scarce. We, therefore, investigated the similarities and differences between these types of tumors to get a better understanding of how they may be more properly diagnosed and treated. The clinical manifestations, CT/MRI findings, pathological characteristics and clinical outcomes of 8 cases of IVOs and 12 cases of CNs were analyzed retrospectively. Both IVO and CN occurred most commonly in young adults and manifested with symptoms of increased intracranial pressure secondary to obstructive hydrocephalus...
September 12, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28879895/perfusion-mr-imaging-of-enhancing-brain-tumors-comparison-of-arterial-spin-labeling-technique-with-dynamic-susceptibility-contrast-technique
#4
Neetu Soni, Devender Pal S Dhanota, Sunil Kumar, Awadhesh K Jaiswal, Arun K Srivastava
OBJECTIVE: Arterial spin labeling (ASL) magnetic resonance (MR) perfusion is a noninvasive and repeatable method for quantitatively measuring cerebral blood flow (CBF). This study aims to compare measurements of ASL-derived CBF with dynamic susceptibility contrast (DSC) MRI in the assessment of enhancing brain tumors (primary and metastatic), with an aim to use ASL as an alternative to DSC. MATERIALS AND METHODS: Thirty patients with newly diagnosed brain tumors (16 meningiomas, 6 gliomas, 3 metastases, 2 cerebellopontine angle schwannoma, 1 central neurocytoma, and 2 low-grade gliomas) were examined using a 3T MR scanner...
September 2017: Neurology India
https://www.readbyqxmd.com/read/28871071/teaching-neuroimages-central-neurocytoma
#5
Matthew Smith-Cohn, Paul A House, Yoshimi Anzai
No abstract text is available yet for this article.
September 5, 2017: Neurology
https://www.readbyqxmd.com/read/28516073/systematic-analysis-of-clinical-outcomes-following-stereotactic-radiosurgery-for-central-neurocytoma
#6
REVIEW
Timothy T Bui, Carlito Lagman, Lawrance K Chung, Stephen Tenn, Percy Lee, Robert K Chin, Tania Kaprealian, Isaac Yang
Central neurocytoma (CN) typically presents as an intraventricular mass causing obstructive hydrocephalus. The first line of treatment is surgical resection with adjuvant conventional radiotherapy. Stereotactic radiosurgery (SRS) was proposed as an alternative therapy for CN because of its lower risk profile. The objective of this systematic analysis is to assess the efficacy of SRS for CN. A systematic analysis for CN treated with SRS was conducted in PubMed. Baseline patient characteristics and outcomes data were extracted...
April 2017: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/28408259/pediatric-basal-ganglia-region-tumors-clinical-and-radiologic-features-correlated-with-histopathologic-findings
#7
Wei Fu, Yan Ju, Si Zhang, Chao You
PURPOSE: To summarize the clinical and radiologic features of pediatric basal ganglia region tumors (PBGRT) in correlation with their histopathologic findings to reduce inappropriate surgery and identify tumors that can benefit from maximal safe resection. METHODS: The records of 35 children with PBGRT treated in our hospital from December 2011 to December 2015 were analyzed retrospectively. The clinical and radiologic features of these tumors were summarized and correlated with their histopathologic diagnosis...
July 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28236180/supraorbital-subfrontal-trans-laminar-endoscope-assisted-approach-for-tumors-of-the-posterior-third-ventricle
#8
Maurizio Iacoangeli, Roberto Colasanti, Domenic Esposito, Alessandro Di Rienzo, Lucia di Somma, Mauro Dobran, Maurizio Gladi, Massimo Scerrati
BACKGROUND: Different surgical approaches have been developed for dealing with third ventricle lesions, all aimed at obtaining a safe removal minimizing brain manipulation. The supraorbital subfrontal trans-lamina terminalis route, commonly employed only for the anterior third ventricle, could represent, in selected cases with endoscopic assistance, an alternative approach to posterior third ventricular lesions. METHODS: Seven patients underwent a supraorbital subfrontal trans-laminar endoscope-assisted approach to posterior third ventricle tumors (two craniopharyngiomas, one papillary tumor of the pineal region, one pineocytoma, two neurocytomas, one glioblastoma)...
April 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28230467/ultrastructural-comparison-of-extraventricular-and-central-neurocytomas
#9
Sergei I Bannykh, Miriam Nuno
No abstract text is available yet for this article.
January 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28217163/pediatric-central-neurocytoma-case-report-and-review-of-literature
#10
Basanta Kumar Baishya, Rishi Kant Singh, Deep Dutta, Zakir Hussain
Central neurocytomas are slow-growing primary brain tumors of neuronal origin having a predilection to arise mostly in the lateral ventricles. We report a case of a 9-year-old girl who presented with headache and vomiting of 1-month duration. Her magnetic resonance imaging was suggestive of central neurocytoma of the third ventricle and was surgically managed, and tumor tissue was sent for histopathology and immunohistochemistry which confirmed the diagnosis.
October 2016: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/28120072/ventricular-central-neurocytoma-rate-of-shunting-and-outcome-2-years-after-total-and-subtotal-excision
#11
Wessam Samir Soliman
BACKGROUND: Central neurocytoma is an intraventricular tumor that affects young adults. It has a favorable prognosis after adequate surgical intervention; however, an aggressive course may take place in some cases. OBJECTIVE: The objective of the study was to evaluate the rate of shunting and the outcome of control measures in patients with central neurocytoma submitted to total and subtotal excision. METHODS: Twelve patients were included in this study, with a follow-up of 24 months...
2017: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/28077908/magnetic-resonance-imaging-of-a-case-of-central-neurocytoma
#12
Kreshnike Dedushi, Serbeze Kabashi, Mehmet Sahin Ugurel, Naser Ramadani, Sefedin Mucaj, Kamber Zeqiraj
BACKGROUND: The purpose of this study is to investigate the MRI features of central neurocytoma. CASE REPORT: A 45 year old man with 3 months of worsening daily headaches. These headaches were diffuse, lasted for several hours, and mostly occurred in the morning. She was initially diagnosed and treated for migraines but later he had epileptic attack and diplopia and neurolog recomaded MRI. METHODS: precontrast MRI; TSE/T2Wsequence in axial/coronal planes; 3D-Hi-resolution T1W sagittal; FLAIR/T2W axial; FLAIR/T2W and Flash/T2W oblique coronal plane (perpendicular to temporal lobes) GRE/T2W axial plane for detection of heme products...
December 2016: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/27941295/mr-spectroscopy-to-distinguish-between-supratentorial-intraventricular-subependymoma-and-central-neurocytoma
#13
Fumiaki Ueda, Hiroyuki Aburano, Yasuji Ryu, Yuichi Yoshie, Mitsutoshi Nakada, Yutaka Hayashi, Osamu Matsui, Toshifumi Gabata
PURPOSE: The purpose of this study was to discriminate supratentorial intraventricular subependymoma (SIS) from central neurocytoma (CNC) using magnetic resonance spectroscopy (MRS). METHODS: Single-voxel proton MRS using a 1.5T or 3T MR scanner from five SISs, five CNCs, and normal controls were evaluated. They were examined using a point-resolved spectroscopy. Automatically calculated ratios comparing choline (Cho), N-acetylaspartate (NAA), myoinositol (MI), and/or glycine (Gly) to creatine (Cr) were determined...
December 12, 2016: Magnetic Resonance in Medical Sciences: MRMS
https://www.readbyqxmd.com/read/27910945/thyroid-transcription-factor-1-distinguishes-subependymal-giant-cell-astrocytoma-from-its-mimics-and-supports-its-cell-origin-from-the-progenitor-cells-in-the-medial-ganglionic-eminence
#14
Jen-Fan Hang, Chih-Yi Hsu, Shih-Chieh Lin, Chih-Chun Wu, Han-Jui Lee, Donald Ming-Tak Ho
Subependymal giant cell astrocytoma is a benign brain tumor mostly associated with tuberous sclerosis complex. However, it may be misinterpreted as other high-grade brain tumors due to the presence of large tumor cells with conspicuous pleomorphism and occasional atypical features, such as tumor necrosis and endothelial proliferation. In this study, we first investigated thyroid transcription factor-1 (TTF-1) expression in a large series of subependymal giant cell astrocytomas and other histologic and locational mimics to validate the diagnostic utility of this marker...
December 2, 2016: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/27867912/central-neurocytoma-a-review-of-clinical-management-and-histopathologic-features
#15
REVIEW
Seung J Lee, Timothy T Bui, Cheng Hao Jacky Chen, Carlito Lagman, Lawrance K Chung, Sabrin Sidhu, David J Seo, William H Yong, Todd L Siegal, Minsu Kim, Isaac Yang
Central neurocytoma (CN) is a rare, benign brain tumor often located in the lateral ventricles. CN may cause obstructive hydrocephalus and manifest as signs of increased intracranial pressure. The goal of treatment for CN is a gross total resection (GTR), which often yields excellent prognosis with a very high rate of tumor control and survival. Adjuvant radiosurgery and radiotherapy may be considered to improve tumor control when GTR cannot be achieved. Chemotherapy is also not considered a primary treatment, but has been used as a salvage therapy...
October 2016: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/27864704/a-clinicopathologic-study-of-extraventricular-neurocytoma
#16
Li Xu, Zhaolian Ouyang, Junmei Wang, Zhaoxia Liu, Jingyi Fang, Jiang Du, Yanjiao He, Guilin Li
In 2007, extraventricular neurocytoma was classified as a separate entity among glioneuronal tumors. However, extraventricular neurocytoma is not fully understood and may be misdiagnosed. Here, we describe the clinical and pathological features, prognoses, and treatments of 13 extraventricular neurocytoma cases, and compare their immunophenotypes with those of oligodendroglioma, diffuse astrocytoma, and ependymoma. Six typical and 7 atypical cases comprised the 13 extraventricular neurocytoma cases. Histological features included oligodendroglioma-like perinuclear halo, neuropil-like matrix, ganglion or ganglioid cells, perivascular pseudorosettes, vessel hyalinization, calcifications, and myxoid degeneration...
March 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/27777164/upfront-gamma-knife-surgery-for-giant-central-neurocytoma
#17
REVIEW
Kuan-Pin Chen, Cheng-Chia Lee, Chia-Lin Liao, Tao-Chieh Yang, Tsung-Lang Chiu, Chain-Fa Su
BACKGROUND: In this report, we present the results of using upfront Gamma Knife surgery (GKS) in the management of giant central neurocytoma (CNC) (volume >50 mL) without the initial removal of the tumor mass. CASE DESCRIPTIONS: Two patients underwent GKS for histologically proven CNC. Clinical and imaging studies were performed to evaluate the response to treatment. GKS involved delivery doses of 12 or 13 Gy to the tumor margin at the isodose line of 50%. Tumor response to GKS appeared as early as 4-6 months after GKS, at which point a dramatic reduction in volume was observed...
January 2017: World Neurosurgery
https://www.readbyqxmd.com/read/27753657/a-comparative-immunohistochemical-study-of-epithelial-membrane-antigen-and-nherf1-ebp50-in-the-diagnosis-of-ependymomas
#18
Aruna Nambirajan, Mehar C Sharma, Madhu Rajeshwari, Aanchal Kakkar, Vaishali Suri, Chitra Sarkar
Ependymomas are gliomas that recapitulate normal ependymal cells. The epithelial membrane antigen (EMA) shows "dot-like" and "ring-like" staining patterns, highlighting "microlumens" or intracytoplasmic rosettes, a pathognomonic ultrastructural feature. NHERF1/EBP50, an adaptor protein localized at the apical plasma membrane of human epithelia, has been found to localize to these microlumens. We aimed to analyze the staining patterns of EMA and EBP50 in ependymomas and other tumors, and thereby compare their diagnostic utility...
October 7, 2016: Applied Immunohistochemistry & Molecular Morphology: AIMM
https://www.readbyqxmd.com/read/27664193/pediatric-central-neurocytoma
#19
Madhivanan Karthigeyan, Kirti Gupta, Pravin Salunke
Central neurocytomas are well-differentiated tumors of neuronal origin. These are relatively uncommon in the pediatric population. Anaplastic features reflected by brisk mitotic activity, microvascular proliferation, necrosis, and MIB-1 labeling index >2% or 3% have been proposed to indicate aggressive behavior. Because of its rarity, there is paucity of data regarding the histologic spectrum and outcome of central neurocytomas in children. With this short series, we describe our observations of the clinicopathologic characteristics and outcome of this tumor in children over a 5-year period...
January 2017: Journal of Child Neurology
https://www.readbyqxmd.com/read/27659827/glioneuronal-tumors-of-cerebral-hemisphere-in-children-correlation-of-surgical-resection-with-seizure-outcomes-and-tumor-recurrences
#20
Tadanori Tomita, Jerome M Volk, Wenjun Shen, Tatiana Pundy
OBJECT: Glioneuronal tumors are common neoplasms among the cerebral hemisphere during childhood. They consist of several histological types, of which gangliogliomas (GGs) and dysembryoplastic neuroepithelial tumors (DNTs) are most common and often present with seizures. A great majority of glioneuronal tumors are benign. However, there are conflict reports regarding postoperative tumor recurrence rates and seizure control. The authors analyzed and compared these tumors for their locations and histology and the tumor and seizure control following resection...
October 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
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