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https://www.readbyqxmd.com/read/28213307/enhanced-toxicity-to-the-cyanobacterium-microcystis-aeruginosa-by-low-dosage-repeated-exposure-to-the-allelochemical-n-phenyl-1-naphthylamine
#1
Y N Gao, F J Ge, L P Zhang, Y He, Z Y Lu, Y Y Zhang, B Y Liu, Q H Zhou, Z B Wu
It has been puzzling whether and how a plant could exert a strong allelopathic inhibition to the target organisms by releasing low concentrations of allelochemicals. Plant allelochemicals have been proposed to be released continuously, however, direct evidence from specific allelochemicals is urgently required. In the present study, the toxicity of allelochemical N-phenyl-1-naphthylamine (NPN) towards the cyanobacterium Microcystis aeruginosa by two different exposure patterns was compared. One was low-dosage repeated exposure (LRE), in which 50  μg L(-1) NPN was repeatedly dosed to simulate the continual release of allelochemicals, and the other one was high-dosage single exposure (HSE) as per the routine toxicity assay...
January 21, 2017: Chemosphere
https://www.readbyqxmd.com/read/28208440/charge-segregation-in-weakly-ionized-microgels
#2
John S Hyatt, Alison M Douglas, Chris Stanley, Changwoo Do, Thomas H Barker, Alberto Fernández-Nieves
We investigate microgels synthesized from N-isopropylacrylamide (NIPAM) copolymerized with a large mol% of acrylic acid, finding that when the acid groups are partially ionized at high temperatures, competition between ion-induced swelling and hydrophobic deswelling of poly(NIPAM) chains results in microphase separation. In cross-linked microgels, this manifests as a dramatic decrease in the ratio between the radius of gyration and the hydrodynamic radius to ∼0.2, indicating that almost all the mass of the microgel is concentrated near the particle center...
January 2017: Physical Review. E
https://www.readbyqxmd.com/read/28207831/the-relationship-between-rassf1a-gene-promoter-methylation-and-the-susceptibility-and-prognosis-of-melanoma-a-meta-analysis-and-bioinformatics
#3
Chihao Shao, Wenzhu Dai, Haili Li, Wenru Tang, Shuting Jia, Xiaoming Wu, Ying Luo
BACKGROUND: The function of the tumor suppressor gene RASSF1A in cancer cells has been detailed in many studies. However, due to the methylation of its promoter, the expression of RASSF1A is missing in most cancers. In the literature, we found that the conclusion regarding the relationship between RASSF1A gene promoter methylation and the susceptibility and prognosis of melanoma was not unified. This study adopts the use of a meta-analysis and bioinformatics to explore the relationship between RASSF1A gene promoter methylation and the susceptibility and prognosis of melanoma...
2017: PloS One
https://www.readbyqxmd.com/read/28174444/does-the-q-h-index-show-a-stronger-relationship-than-the-h-q-ratio-in-regard-to-knee-pain-during-daily-activities-in-patients-with-knee-osteoarthritis
#4
Remi Fujita, Yasumoto Matsui, Atsushi Harada, Marie Takemura, Izumi Kondo, Tetsuya Nemoto, Tadahiro Sakai, Hideki Hiraiwa, Susumu Ota
[Purpose] The purpose of this study was to elucidate the relationship between knee muscle strength and knee pain in activities of daily living, based on consideration of the difference between extension and flexion strength (Q - H) and the hamstring:quadriceps (H:Q) ratio in patients with knee osteoarthritis. [Subjects and Methods] The participants were 78 females with knee osteoarthritis, and a total of 133 knees that had not been treated surgically were the targets of this research. The legs were divided according to dominance...
December 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28173653/-coenzyme-q-10-treatment-for-one-child-with-coq6-gene-mutation-induced-nephrotic-syndrome-and-literature-review
#5
Q Cao, G M Li, H Xu, Q Shen, L Sun, X Y Fang, H M Liu, W Guo, Y H Zhai, B B Wu
Objective: To summarize the clinical manifestation and molecular characteristics of COQ6 mutation induced nephrotic syndrome, and to evaluate efficacy of CoQ(10) therapy. Method: Clinical data of the case with infantile nephrotic syndrome was summarized, including clinical manifestations, laboratory findings and family investigation. The patient received CoQ(10) 30 mg/(kg·d) therapy. Urine protein/creatinine ratio, serum albumin and creatinine were detected to assess the efficacy of the therapy. Result: (1) The 10 months old boy was presented with nephrotic level proteinuria and hypoalbuminemia...
February 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28165560/diagnostic-value-of-micrornas-in-breast-cancer-a-meta-analysis
#6
Z-C Xin, H-Q Yang, X-W Wang, Q Zhang
OBJECTIVE: To explore the value of diagnosis accuracy of aberrant microRNAs in breast cancer. MATERIALS AND METHODS: We searched PubMed, Embase, EBSCO and the Cochrane Library, accessing to the case of articles about microRNA expression in breast carcinoma patients after literature screening and quality assessment, extracting data from included studies and using Stata 14.0 analysis data for meta-analysis. RESULTS: 14 English studies met the inclusion criteria...
January 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28162156/-the-clinical-practice-of-improvement-the-volume-and-quality-of-functional-liver-in-autologous-liver-transplantation-for-the-patients-with-alveolar-echinococcosis
#7
Aji Tuerganaili, Y M Shao, J M Zhao, T Li, B Ran, T M Jiang, R Q Zhang, Tuxun Tuerhongjiang, L Wu, M Guo, H Wen
Objective: To investigate the clinical significance of accurate assessment of "volume and quality" of functional liver in Autologous liver transplantation (ALT) in the treatment of the advanced hepatic alveolar echinococcosis (HAE). Methods: The clinical data of 12 patients with advanced HAE who underwent ALT at the First Affiliated Hospital of Xinjiang Medical University from May 2015 to July 2016 were retrospectively analyzed. Results: The preoperative hepatic functions of 12 patients were 8 Child-Pugh Grade A, 1 Grade B, and 3 Grade C...
January 24, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28160183/effects-of-precursor-solution-composition-on-the-performance-and-i-v-hysteresis-of-perovskite-solar-cells-based-on-ch3nh3pbi3-xclx
#8
Z L Zhang, B Q Men, Y F Liu, H P Gao, Y L Mao
Precursor solution of CH3NH3PbI3-xClx for perovskite solar cells was conventionally prepared by mixing PbCl2 and CH3NH3I with a mole ratio of 1:3 (PbCl2:CH3NH3I). While in the present study, CH3NH3PbI3-xClx-based solar cells were fabricated using the precursor solutions containing PbCl2 and CH3NH3I with the mole ratios of 1:3, 1.05:3, 1.1:3, and 1.15:3, respectively. The results display that the solar cells with the mole ratio of 1.1:3 present higher power conversion efficiency and less I-V hysteresis than those with the mole ratio of 1:3...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28151895/association-between-il-1%C3%AE-polymorphisms-and-gastritis-risk-a-meta-analysis
#9
Xiaoming Sun, Hongxing Cai, Zhouru Li, Shanshan Li, Wenjiang Yin, Guokai Dong, Jinxia Kuai, Yihui He, Jing Jia
BACKGROUND: Helicobacter pylori (H. pylori) infection of the human stomach regularly leads to chronic gastric inflammation. The cytokine gene interleukin (IL)-1β has been implicated in influencing the pathology of inflammation induced by H. pylori infection. Currently, several studies have been carried out to investigate the association of IL-1β-511 (rs16944) and IL-1β-31 (rs1143627) polymorphisms with gastritis risk; however, the results are inconsistent and inconclusive. To assess the effect of IL-1β polymorphisms on gastritis susceptibility, we conducted a meta-analysis...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28128508/the-influence-of-age-at-menarche-menstrual-cycle-length-and-bleeding-duration-on-time-to-pregnancy-a-large-prospective-cohort-study-among-rural-chinese-women
#10
Q Zhang, Y Y Wang, Y Zhang, H G Zhang, Y Yang, Y He, J H Xu, J Zhao, Z Q Peng, X Ma
OBJECTIVE: To investigate the relations among age at menarche (AAM), menstrual cycle length, menstrual bleeding duration and time to pregnancy in a large cohort of rural Chinese women. DESIGN: A prospective cohort study. SETTING: Local family-planning service agencies and maternal/child care service centres. POPULATION: A total of 391 320 rural women of reproductive age who participated in the National Free Pre-pregnancy Checkups and were planning to conceive were enrolled...
January 27, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28128397/meta-analysis-of-tp73-polymorphism-and-cervical-cancer
#11
H Feng, L Sui, M Du, Q Wang
The aim of this study was to investigate the tumor protein p73 (TP73) G4C14-A4T14 polymorphism and to perform a meta-analysis to assess TP73 expression in cervical cancer and precancerous tissue. Articles containing data regarding TP73 status in cervical cancer patients and healthy controls were retrieved from PubMed, EMBASE, Cochrane, Chinese Biomedical Literature, and China National Knowledge Infrastructure databases. Then, the quality of the studies was evaluated according to inclusion and exclusion criteria...
January 23, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28112770/depressive-symptoms-increase-the-risk-of-mild-neurocognitive-disorders-among-elderly-chinese
#12
L Feng, W-S Lim, M-S Chong, T-S Lee, Q Gao, M S Z Nyunt, L Feng, E-H Kua, T-P Ng
BACKGROUND: Depression is prevalent among patients with late life neurocognitive disorders but its role as an independent risk factor is not established. We aimed to examine the longitudinal relationship between depression and the incidence of mild neurocognitive disorders (NCD) in a Chinese population. METHODS: We analyzed data from 889 community-living Chinese elderly in the Singapore Longitudinal Aging Study (SLAS) cohort. All subjects were cognitively normal at baseline based on their performance on the Mini-Mental State Examination (MMSE)...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28111775/effects-of-synbiotic-supplementation-on-growth-performance-carcass-characteristics-meat-quality-and-muscular-antioxidant-capacity-and-mineral-contents-in-broilers
#13
Y F Cheng, Y P Chen, X H Li, W L Yang, C Wen, Y R Kang, A Q Wang, Y M Zhou
BACKGROUD: The present study was conducted to investigate the effects of dietary synbiotic supplementation on growth performance, carcass composition, meat quality and muscular antioxidant capacity and mineral contents in broilers. 96 day-old male broiler chicks (Arbor Acres Plus) were randomly allocated to 2 groups, and each group consisted of 6 replicates with 8 chicks each. Birds were fed a corn-soybean meal basal diet supplemented with either 0 or 1.5 g · kg(-1) synbiotic consisted of probiotics (Bacillus subtilis, Bacillus licheniformis, and Clostridium butyricum) and prebiotics (yeast cell wall and xylooligosaccharide) from 1 to 42 days of age...
January 23, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28101814/arbutus-andrachne-l-reverses-sleep-deprivation-induced-memory-impairments-in-rats
#14
Karem H Alzoubi, Bayan S Malkawi, Omar F Khabour, Tamam El-Elimat, Feras Q Alali
Sleep deprivation (SD) is associated with cognitive deficits. It was found to affect the hippocampus region of the brain by impairing memory formation. This impairment is suggested to be caused by elevation in oxidative stress in the body, including the brain during SD. It was hypothesized that the methanolic extract of the fruits of Arbutus andrachne L. (Ericaceae) will prevent chronic SD-induced impairment of hippocampal memory via its antioxidative properties. The methanolic extract of the fruits of A. andrachne was evaluated for its beneficial properties to reverse SD-induced cognitive impairment in rats...
January 18, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28101624/the-safety-and-efficacy-of-cardiac-contractility-modulation-in-heart-failure-a%C3%A2-meta-analysis-of-clinical-trials
#15
X Liu, H J Yang, H Q Ping, S Qiu, S Shi, B Yang
BACKGROUND: Cardiac contractility modulation (CCM) has developed as a promising treatment device for heart failure (HF). This meta-analysis aimed at systematically reviewing the latest available published trials to provide evidence on the safety and efficacy of CCM in patients with HF. METHODS: We searched the Cochrane Central Resister of Controlled Trials, PubMed, and EMBASE in May 2016 to identify eligible clinical trials comparing CCM with sham treatment or with usual care...
January 18, 2017: Herz
https://www.readbyqxmd.com/read/28100382/-epidemiological-pattern-of-abnormal-urinary-fluoride-rates-in-population-with-occupational-fluoride-exposure-in-shanghai
#16
M H Gu, J Su, C H Liu, Y Q Zhu, H Shen, Y H Huang, L Zhong, M H Zhang, Y H Li
Objective: To investigate the epidemiological features of abnormal urinary fluoride rates in population with occupational exposure, and its relationships with age, work years and gender in Shanghai. Methods: A questionnaire survey was conducted respectively in 4 999 exposed workers and 283 non-exposed people during 2012-2015. Their urine samples were collected in plastic bottles and the fluoride ion selective electrode method was used for urinary fluoride level analysis. Logistic regression model was used to estimate associations between the abnormal rates and demographic/socioeconomic status of the study subjects...
January 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28091429/chronic-kidney-disease-in-chinese-postmenopausal-women-a-cross-sectional-survey
#17
F Pei, Z Zhou, Y Li, Y Ren, X Yang, G Liu, Q Xia, Z Hu, L Zhang, M Zhao, H Wang
INTRODUCTION: Despite advances in the management of chronic kidney disease (CKD), there is ongoing uncertainty regarding the prevalence of CKD in postmenopausal women. This study was designed to investigate both CKD prevalence and related risk factors in a cohort of postmenopausal Chinese women. MATERIALS AND METHODS: A cross-sectional survey was administered to a nationally representative sample of female Chinese participants, including a total of 47,204 subjects, among whom were 8573 self-reported postmenopausal women...
February 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28089376/chemotherapy-completion-in-elderly-women-with-ovarian-primary-peritoneal-or-fallopian-tube-cancer-an-nrg-oncology-gynecologic-oncology-group-study
#18
Vivian E von Gruenigen, Helen Q Huang, Jan H Beumer, Heather A Lankes, William Tew, Thomas Herzog, Arti Hurria, Robert S Mannel, Tina Rizack, Lisa M Landrum, Peter G Rose, Ritu Salani, William H Bradley, Thomas J Rutherford, Robert V Higgins, Angeles Alvarez Secord, Gini Fleming
PURPOSE: A simple measure to predict chemotherapy tolerance in elderly patients would be useful. We prospectively tested the association of baseline Instrumental Activities of Daily Living (IADL) score with ability to complete 4 cycles of first line chemotherapy without dose reductions or >7days delay in elderly ovarian cancer patients. PATIENTS AND METHODS: Patients' age ≥70 along with their physicians chose between two regimens: CP (Carboplatin AUC 5, Paclitaxel 135mg/m(2)) or C (Carboplatin AUC 5), both given every 3weeks either after primary surgery or as neoadjuvant chemotherapy (NACT) with IADL and quality of life assessments performed at baseline, pre-cycle 3, and post-cycle 4...
January 12, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28088140/ring-polymer-molecular-dynamics-studies-on-the-rate-coefficient-of-the-abstraction-channel-of-hydrogen-plus-ethane-propane-and-dimethyl-ether
#19
Qingyong Meng, Jun Chen
To accurately compute the rates of the abstraction channels of hydrogen plus ethane (Et), propane (Pr), and dimethyl ether (DME), ring-polymer molecular dynamics (RPMD) method is used in conjunction with the recently constructed local permutation invariant polynomial neural-networks potential energy surface of the parent H + CH4 system [Q. Meng et al., J. Chem. Phys. 144, 154312 (2016)]. For H + Et, one of the H atoms in CH4 of the parent system is replaced by a methyl group, while for the H + DME reaction, it is replaced by the methoxyl group...
January 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28075131/classical-galactosemia-insight-into-molecular-pathomechanisms-by-differential-membrane-proteomics-of-fibroblasts-under-galactose-stress
#20
Simon Staubach, Stefan Müller, Murat Pekmez, Franz-Georg Hanisch
Classical galactosemia, a hereditary metabolic disease caused by the deficiency of galactose-1-phosphate uridyltransferase (GALT; EC 2.7.712), results in an impaired galactose metabolism and serious long-term developmental affection of the CNS and ovaries, potentially related in part to endogenous galactose-induced protein dysglycosylation. In search for galactose-induced changes in membrane raft proteomes of GALT-deficient cells, we performed differential analyses of lipid rafts from patient-derived (Q) and sex- and age-matched control fibroblasts (H) in the presence or absence of the stressor...
January 24, 2017: Journal of Proteome Research
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