keyword
MENU ▼
Read by QxMD icon Read
search

Vitreoretinal lymphoma

keyword
https://www.readbyqxmd.com/read/28451463/macular-edema-is-a-rare-finding-in-untreated-vitreoretinal-lymphoma-small-case-series-and-review-of-the-literature
#1
REVIEW
Elisa Carreras, Diva R Salomão, Jeroni Nadal, Sejal R Amin, Harish Raja, Thomas J Grube, Ryan L Geraets, Patrick B Johnston, Brian P O'Neill, Jose S Pulido
BACKGROUND: To determine the occurrence of macular edema (ME) in vitreoretinal lymphoma (VRL). METHODS: Retrospective analysis of 17 patients (31 eyes) with VRL. A review of the literature was done as well. RESULTS: Nine patients (15 eyes) had fluorescein angiography and/or optical coherence tomography at presentation. In the ME group (six eyes of four patients), three patients (five eyes) had prior chemotherapy and radiation. Excluding eyes with radiation retinopathy (three eyes), rate of ME was 25% (3/12)...
2017: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/28419996/polydimethyl-siloxane-as-an-internal-tamponade-for-vitreoretinal-surgery
#2
Rumana N Hussain, Jayavani Myneni, Theodor Stappler, David Wong
PURPOSE: To report the efficacy and safety of polydimethyl siloxane (Siluron Xtra®) as an internal tamponade. DESIGN: Audit and adverse event screening of procedures (March 2014-2015). METHODS: Patients who had undergone vitreoretinal procedures with Siluron Xtra® tamponade were retrospectively analysed with respect to anatomical outcome, visual outcomes, and perioperative complications, in particular intraocular pressure. INCLUSION CRITERIA: all patients who had undergone Siluron Xtra® tamponade...
April 19, 2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/28359629/-multimodal-imaging-in-primary-intraocular-lymphoma
#3
S Santos, M L Le Lez, S Arsène, P J Pisella
INTRODUCTION: Vitreoretinal lymphoma is a serious disease with highly varied clinical presentations. The goal of this work is to identify the various presentations (clinical, imaging) in order to improve screening for this disease. MATERIALS AND METHOD: We collected data of patients followed on our service for vitreoretinal lymphoma. The fundus exam, autofluorescence and angiography data were classified in order to identify signs, which might lead to earlier diagnosis of lymphoma...
April 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28273192/-primary-central-nervous-system-lymphoma-pathogenesis-and-histomorphology
#4
Gábor Méhes
Lymphoproliferative diseases of the central nervous system are rare, diagnostics and treatment are accordingly challenging. Since the introduction of the 2008 WHO lymphoma classification, primary CNS DLBCL - also covering the associated primary ocular (vitreoretinal) lymphoma - is a separate entity. The special localization is related with a series of newly recognized genetic, genomic and immunologic features directing to the strong interaction between transformed lymphoma cells, neural tissue components and the local immune response...
March 8, 2017: Magyar Onkologia
https://www.readbyqxmd.com/read/28128370/an-ocular-protein-triad-can-classify-four-complex-retinal-diseases
#5
J J W Kuiper, L Beretta, S Nierkens, R van Leeuwen, N H Ten Dam-van Loon, J Ossewaarde-van Norel, M C Bartels, J D F de Groot-Mijnes, P Schellekens, J H de Boer, T R D J Radstake
Retinal diseases generally are vision-threatening conditions that warrant appropriate clinical decision-making which currently solely dependents upon extensive clinical screening by specialized ophthalmologists. In the era where molecular assessment has improved dramatically, we aimed at the identification of biomarkers in 175 ocular fluids to classify four archetypical ocular conditions affecting the retina (age-related macular degeneration, idiopathic non-infectious uveitis, primary vitreoretinal lymphoma, and rhegmatogenous retinal detachment) with one single test...
January 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28039672/two-cases-of-primary-vitreoretinal-lymphoma-a-diagnostic-challenge-the-supporting-role-of-multimodal-imaging-in-the-diagnosis-of-primary-vitreoretinal-lymphoma
#6
Mariachiara Morara, Federico Foschi, Chiara Veronese, Carlo Torrazza, Francesco Bacci, Vittorio Stefoni, P Antonio Ciardella
PURPOSE: To report two cases of primary vitreoretinal lymphoma (PVRL), which presented as intermediate and posterior uveitis. METHODS: Combined clinical assessment, multimodal imaging with spectral-domain optical coherence tomography, fundus autofluorescence, fluorescein angiography, indocyanine green angiography, brain magnetic resonance imaging and vitreous and retinal biopsy. Case 1 was a 48-year-old woman who complained of visual loss in her right eye secondary to a diffuse vitreous opacification and multiple chorioretinal lesions...
December 30, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/28002793/next-generation-sequencing-of-vitreoretinal-lymphomas-from-small-volume-intraocular-liquid-biopsies-new-routes-to-targeted-therapies
#7
Andi K Cani, Daniel H Hovelson, Hakan Demirci, Mark W Johnson, Scott A Tomlins, Rajesh C Rao
BACKGROUND: Vitreoretinal lymphoma (VRL), the most common lymphoma of the eye, is a rare form of primary CNS lymphoma (PCNSL). Most frequently a high-grade diffuse large B cell lymphoma, VRL can cause vision loss and its prognosis remains dismal: the overall survival time is 3 years after diagnosis. Radiotherapy and chemotherapy are used but remain frequently ineffective, and no standardized treatment regimen exists. Furthermore, no biologically targeted treatments, based on the genetic profile of the tumor, are available, as VRL has hitherto not comprehensively been profiled...
January 31, 2017: Oncotarget
https://www.readbyqxmd.com/read/27843904/histopathologic-diagnosis-of-atypical-primary-vitreoretinal-lymphoma-following-enucleation
#8
Arjun B Sood, Steven Yeh, Pia Mendoza, Hans E Grossniklaus
INTRODUCTION: Primary vitreoretinal lymphoma (PVRL) is a rare but potentially fatal malignancy. The diagnosis of PVRL remains challenging. Here, we present a case of PVRL with a diagnostic enucleation required to establish the diagnosis. METHODS/CASE DESCRIPTION: A 58-year-old otherwise healthy woman was referred for evaluation of panuveitis with persistent blurred vision in the left eye. Extensive laboratory work-up was negative. On initial evaluation, the patient had visual acuity of no light perception in the left eye...
October 2016: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/27627063/multimodal-imaging-of-vitreoretinal-lymphoma
#9
Chiara Mapelli, Alessandro Invernizzi, Giulio Barteselli, Marco Pellegrini, Elena Tabacchi, Giovanni Staurenghi, Francesco Viola
PURPOSE: To assess the characteristics and prevalence of fundus abnormalities in vitreoretinal lymphoma (VRL) using multimodal imaging. METHODS: We retrospectively reviewed chart and imaging studies of patients diagnosed with VRL. RESULTS: All 10 VRL patients (14 eyes) included in the study showed vitreitis, hyperreflective lesions on near-infrared reflectance imaging, and hypoautofluorescent lesions on fundus autofluorescence. Other findings included hypofluorescent lesions on fluorescein angiography (79%), hypocyanescent lesions on indocyanine green angiography (77%), small retinal pigment epithelium detachments (PEDs) (71%) and large PEDs (36%) on optical coherence tomography (OCT)...
2016: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/27408377/primary-intraocular-diffuse-large-b-cell-lymphoma-diagnostic-difficulties-in-deep-retinal-infiltrations-with-vitritis
#10
Katarzyna Kapelko-Slowik, Donata Urbaniak-Kujda, Anna Turno-Krecicka, Stanislaw Potoczek, Jaroslaw Dybko, Monika Biernat, Miroslaw Slowik
PURPOSE: Primary intraocular lymphoma (PIOL) is a rare malignancy with an aggressive clinical course. It is usually considered as a subset of primary central nervous system lymphoma. Differential diagnosis should include infectious and non-infectious aetiologies, particularly the common masqueraders sarcoidosis, tuberculosis, viral retinitis and syphilis. PATIENT: The article presents a case of bilateral vitreoretinal lymphoma manifesting as uveitis and vitritis resistant to corticosteroid therapy...
June 2016: Indian Journal of Hematology & Blood Transfusion
https://www.readbyqxmd.com/read/27391815/recurrent-pseudohypopyon-in-association-with-primary-vitreoretinal-lymphoma-a-case-report
#11
Masahiro Kitao, Noriyasu Hashida, Kohji Nishida
BACKGROUND: Primary vitreoretinal lymphoma (PVRL) is a rare and fatal ocular malignancy that is mostly classified as diffuse large B cell lymphoma (DLBCL). PVRL is often fatal because of its association with the central nervous system (CNS). PVRL frequently masquerades as uveitis and sometimes recurs in clinical findings as keratic precipitates (KPs) and subretinal lesions. Pseudohypopyon is one of the clinical findings of the local recurrence of PVRL and is treated with radiotherapy; however, the effectiveness of local control with an intravitreal injection of methotrexate (MTX) has not yet been determined...
July 8, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27380976/vitreoretinal-lymphomas-misdiagnosed-as-uveitis-lessons-learned-from-a-case-series
#12
Luca Cimino, Marco Coassin, Chi-Chao Chan, Sylvia Marchi, Matteo Belpoliti, Andrea Fanti, Alfonso Iovieno, Luigi Fontana
PURPOSE: To present challenging cases of vitreoretinal lymphoma (VRL) that was misdiagnosed as uveitis because of the apparent intraocular inflammation. At the light of the new classification of intraocular lymphomas, we detail the characteristics that masqueraded the tumors and the clinical aspects that guided us to the correct diagnosis. MATERIALS AND METHODS: We retrospectively reviewed the patients referred to our uveitis service between January 2006 and December 2014...
May 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27251192/optical-coherence-tomography-manifestations-of-primary-vitreoretinal-lymphoma
#13
Teiko Saito, Nobuyuki Ohguro, Chiharu Iwahashi, Noriyasu Hashida
BACKGROUND: Primary vitreoretinal lymphoma (PVRL), a subset of primary central nervous system lymphoma (PCNSL), is a high-grade malignant tumor that shows various chorioretinal findings. Optical coherence tomography (OCT) is useful for detecting these lesions, and various abnormalities on OCT images have been reported. The purpose of this report was to investigate retrospectively the OCT manifestations of various disease stages and compare the manifestations of pretreatment, recurrent, and chronic cases...
December 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27218787/primary-vitreoretinal-lymphoma-management-of-isolated-ocular-disease
#14
REVIEW
Matthew T Witmer
BACKGROUND: The prognosis for patients with primary vitreoretinal is dismal. The close association of primary vitreoretinal lymphoma with primary central nervous system lymphoma is responsible for high rates of mortality. Traditional treatments consist of systemic chemotherapy and whole-brain radiotherapy. The optimal approach for the treatment of isolated primary vitreoretinal lymphoma is unclear. METHODS: A review of the relevant medical and scientific literature was performed, focusing on the clinical features of primary vitreoretinal lymphoma and the progress made in the management of isolated ocular disease...
April 2016: Cancer Control: Journal of the Moffitt Cancer Center
https://www.readbyqxmd.com/read/27172327/multimodal-imaging-of-spontaneously-shifting-primary-vitreoretinal-lymphoma
#15
Dimosthenis Mantopoulos, Colleen M Cebulla
PURPOSE: To correlate spectral domain optical coherence tomography (SD-OCT) and photographic imaging before and after spontaneous regression of primary vitreoretinal lymphoma (PVRL) lesions. PROCEDURES: We report the case of a 60-year-old female. RESULTS: The patient presented with bilateral creamy deposits under the retina and retinal pigment epithelium (RPE), and lesions were visible along Bruch's membrane with SD-OCT and suspicious for PVRL...
June 2015: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/27152831/delineation-of-choroidal-and-retinal-lesions-in-posterior-uveitis-by-multispectral-wide-field-scanning-laser-ophthalmoscopy
#16
Jared E Knickelbein, Jesia Hasan, Robert B Nussenblatt, H Nida Sen
PURPOSE: To investigate whether wide-field multispectral scanning laser ophthalmoscopy could assist in determining depth of chorioretinal pathology in posterior uveitis. METHODS: Cross-sectional retrospective review of patients with birdshot chorioretinopathy (BCR; 42 eyes of 21 patients) or active primary vitreoretinal lymphoma (PVRL; 18 eyes of 10 patients) who had multispectral wide-field scanning laser ophthalmoscopy (Optos) images. Images acquired with 532 nm and 635 nm lasers were analyzed separately using Optos V Vantage Pro Review software...
November 2016: Retina
https://www.readbyqxmd.com/read/27133587/how-we-diagnose-and-treat-vitreoretinal-lymphoma
#17
REVIEW
Falko Fend, Andrés J M Ferreri, Sarah E Coupland
The eye is a rare site for the development of malignant lymphoma. Based on cell type and involved intraocular structures, which as a whole represent an immune-privileged site, several subtypes of primary intraocular lymphoma need to be discerned. Primary vitreoretinal lymphoma (PVRL), the most common form, is an aggressive B-cell malignancy and considered a subtype of primary central nervous system (CNS) lymphoma. Ocular symptoms are non-specific and often mimic uveitis, frequently resulting in delayed diagnosis...
June 2016: British Journal of Haematology
https://www.readbyqxmd.com/read/27070953/clinical-features-of-systemic-metastatic-retinal-lymphoma-in-japanese-patients
#18
Rumiko Taki, Atsunobu Takeda, Hiroshi Yoshikawa, Takako Fukuhara, Ryoichi Arita, Yoko Suehiro, Ilseung Choi, Yuji Kumano, Takao Nakamura, Tatsuro Ishibashi
PURPOSE: Systemic metastatic retinal lymphoma (SMRL) originates in systemic organs. It has been reported to exhibit clinical features similar to those of primary vitreoretinal lymphoma (PVRL). We report six cases of SMRL in a single-center survey in Japan. METHODS: The clinical and pathologic features in SMRL at the Kyushu University Hospital were retrospectively studied. RESULTS: The mean patient age at the onset of ocular involvement was 75...
April 12, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27003620/clinical-characteristics-of-primary-vitreoretinal-lymphoma-in-an-indian-population
#19
Sarakshi Mahajan, Raje Nijhawan, Aravind Rajwanshi, Samendra Karkhur, Samyak Mulkutar, Mohit Dogra, Vivek Lal, Vishali Gupta, Amod Gupta
PURPOSE: Primary vitreoretinal lymphomas (PVRL) pose a major diagnostic challenge, especially in the countries with a high prevalence of infectious variety of uveitis. The present study aims to report the clinical characteristics and diagnostic difficulties in patients with PVRL in an Indian Population. METHODS: Retrospective chart reviews of 12 patients with a diagnosis of PVRL. RESULTS: The study included 6 men and 6 women, with a mean age of 55...
March 22, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27002464/intraocular-t-cell-lymphoma-clinical-presentation-diagnosis-treatment-and-outcome
#20
Florence Chaput, Radgonde Amer, Edoardo Baglivo, Valerie Touitou, Alexandra Kozyreff, Dominique Bron, Bahram Bodaghi, Phuc LeHoang, Chris Bergstrom, Hans E Grossniklaus, Chi-Chao Chan, Jacob Pe'er, Laure E Caspers
PURPOSE: To report on the clinical data of seven patients with T-cell intraocular lymphoma (IOL). METHODS: Retrospective case series. RESULTS: Seven immunocompetent patients, 12 eyes, 6 women, with T-cell-IOL were included from five countries. Mean age was 53.5 years (range: 25-82). Four patients had systemic-ocular lymphoma, two had CNS-ocular lymphoma, and one had systemic-CNS- ocular lymphoma. Vitritis was the most frequent clinical sign, followed by anterior uveitis and serous retinal detachment...
March 22, 2016: Ocular Immunology and Inflammation
keyword
keyword
38036
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"