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https://www.readbyqxmd.com/read/27863763/guidelines-on-beta-thalassemia-major-regular-blood-transfusion-therapy-associa%C3%A3-%C3%A3-o-brasileira-de-hematologia-hemoterapia-e-terapia-celular-project-guidelines-associa%C3%A3-%C3%A3-o-m%C3%A3-dica-brasileira-2016
#1
Dante Langhi, Eugênia Maria Amorim Ubiali, José Francisco Comenalli Marques, Mônica de Almeida Verissimo, Sandra Regina Loggetto, Antonio Silvinato, Wanderley Marques Bernardo
No abstract text is available yet for this article.
October 2016: Revista Brasileira de Hematologia e Hemoterapia
https://www.readbyqxmd.com/read/27804209/national-registry-of-hemoglobinopathies-in-spain-rephem
#2
Elena Cela, José M Bellón, María de la Cruz, Cristina Beléndez, Rubén Berrueco, Anna Ruiz, Izaskun Elorza, Cristina Díaz de Heredia, Aurea Cervera, Griselda Vallés, J Antonio Salinas, M Teresa Coll, Mar Bermúdez, Marta Prudencio, Bienvenida Argilés, Cruz Vecilla
BACKGROUND: Although highly prevalent throughout the world, the accurate prevalence of hemoglobinopathies in Spain is unknown. PROCEDURE: This study presents data on the national registry of hemoglobinopathies of patients with thalassemia major (TM), thalassemia intermedia (TI), and sickle cell disease (SCD) in Spain created in 2014. Fifty centers reported cases retrospectively. Data were registered from neonatal screening or from the first contact at diagnosis until last follow-up or death...
November 2, 2016: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/27521858/distribution-of-serological-screening-markers-at-a-large-hematology-and-hemotherapy-center-in-minas-gerais-southeastern-brazil
#3
Sônia Mara Nunes da Silva, Milena Batista de Oliveira, Edson Zangiacomi Martinez
OBJECTIVE: To assess the distribution of serological markers in blood donors at the blood banks of the Fundação Centro de Hematologia e Hemoterapia de Minas Gerais (Hemominas), Brazil, between January 2006 and December 2012. METHODS: This is a descriptive, retrospective study on blood donors screened using serological tests for markers of transmitted diseases at the state blood-banking network. RESULTS: Approximately 78.9% of the donors were considered eligible for the study after clinical screening...
July 2016: Revista Brasileira de Hematologia e Hemoterapia
https://www.readbyqxmd.com/read/27521856/dangerous-universal-donors-the-reality-of-the-hemocentro-in-belo-horizonte-minas-gerais
#4
Mariana Martins Godin, Lucas de Oliveira Souza, Luciana Cayres Schmidt, Lauro Mello Vieira, Rejane Silva Diniz, Luci Maria SantAna Dusse
BACKGROUND: The term dangerous universal blood donor refers to potential agglutination of the erythrocytes of non-O recipients due to plasma of an O blood group donor, which contains high titers of anti-A and/or anti-B hemagglutinins. Thus, prior titration of anti-A and anti-B hemagglutinins is recommended to prevent transfusion reactions. OBJECTIVE: The aim of this study was to estimate the frequency of dangerous universal donors in the blood bank of Belo Horizonte (Fundação Central de Imuno-Hematologia - Fundação Hemominas - Minas Gerais) by determining the titers of anti-A and anti-B hemagglutinins in O blood group donors...
July 2016: Revista Brasileira de Hematologia e Hemoterapia
https://www.readbyqxmd.com/read/27374031/-mobilization-of-peripheral-blood-stem-cells-with-plerixafor-in-poor-mobilizer-patients
#5
Juan-Manuel Sancho, Rafael Duarte, Laura Medina, Sergi Querol, Pedro Marín, Anna Sureda
BACKGROUND AND OBJECTIVE: Poor mobilization of peripheral blood stem cells (CD34(+) cells) from bone marrow is a frequent reason for not reaching the autologous stem cell trasplantation (SCT) procedure in patients diagnosed with lymphoma or myeloma. Plerixafor, a reversible inhibitor of the binding of stromal cell-derived factor 1 to its cognate receptor CXCR4, has demonstrated a higher capacity for the mobilization of peripheral blood stem cells in combination with granulocyte colony stimulating factor (G-CSF) compared with G-CSF alone...
September 2, 2016: Medicina Clínica
https://www.readbyqxmd.com/read/27269220/-not-available
#6
María Ballesteros-Pomar, Rocío Villar-Taibo, Alicia Calleja-Fernández, Begoña Pintor-de-la-Maza, Cecilia Álvarez-Del-Campo, Alfonso Vidal-Casariego, Isidoro Cano-Rodríguez
Los datos del estudio PREDYCES® nos revelaron que en España la desnutrición relacionada con la enfermedad (DRE) afecta a uno de cada cuatro pacientes hospitalizados. Esta cifra aumenta hasta el 36,8% en los pacientes hematológicos. Se calcula que un 20% de los pacientes oncológicos muere por complicaciones relacionadas con la DRE. Nuestro grupo se planteó en 2011 comenzar la implantación de un cribado nutricional en los servicios con mayor riesgo de DRE. La presente revisión trata de describir todo el proceso que hemos seguido para mejorar la situación nutricional en los pacientes ingresados en el Servicio de Hematología del Complejo Asistencial Universitario de León (CAULE), mayoritariamente con diagnóstico de neoplasias hematológicas...
2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/27208574/guidelines-on-neonatal-screening-and-painful-vaso-occlusive-crisis-in-sickle-cell-disease-associa%C3%A3-%C3%A3-o-brasileira-de-hematologia-hemoterapia-e-terapia-celular-project-guidelines-associa%C3%A3-%C3%A3-o-m%C3%A3-dica-brasileira-2016
#7
Josefina Aparecida Pellegrini Braga, Mônica Pinheiro de Almeida Veríssimo, Sara Teresinha Olalla Saad, Rodolfo Delfini Cançado, Sandra Regina Loggetto
No abstract text is available yet for this article.
April 2016: Revista Brasileira de Hematologia e Hemoterapia
https://www.readbyqxmd.com/read/27118319/a-prognostic-model-for-survival-after-salvage-treatment-with-flag-ida-gemtuzumab-ozogamicine-in-adult-patients-with-refractory-relapsed-acute-myeloid-leukaemia
#8
Juan M Bergua, Pau Montesinos, David Martinez-Cuadrón, Pascual Fernández-Abellán, Josefina Serrano, María J Sayas, Julio Prieto-Fernandez, Raimundo García, Ana J García-Huerta, Manuel Barrios, Celina Benavente, Manuel Pérez-Encinas, Adriana Simiele, Gabriela Rodríguez-Macias, Pilar Herrera-Puente, Rebeca Rodríguez-Veiga, María P Martínez-Sánchez, María L Amador-Barciela, Rosalía Riaza-Grau, Miguel A Sanz
The combination of fludarabine, cytarabine, idarubicin, and granulocyte colony-stimulating factor (FLAG-Ida) is widely used in relapsed/refractory acute myeloid leukaemia (AML). We retrospectively analysed the results of 259 adult AML patients treated as first salvage with FLAG-Ida or FLAG-Ida plus Gentuzumab-Ozogamicin (FLAGO-Ida) of the Programa Español de Tratamientos en Hematología (PETHEMA) database, developing a prognostic score system of survival in this setting (SALFLAGE score). Overall, 221 patients received FLAG-Ida and 38 FLAGO-Ida; 92 were older than 60 years...
September 2016: British Journal of Haematology
https://www.readbyqxmd.com/read/27079395/thrombosis-in-newborn-infants
#9
REVIEW
Viviana Bacciedoni, Myriam Attie, Hugo Donato
The incidence of thrombosis is higher among newborn infants than in any other stage of pediatric development. This fact is the consequence of labile characteristics of the neonatal hemostatic system, in addition to exposure to multiple risk factors and the wide use of vascular catheters. Venous thromboses, which mainly affect the limbs, the right atrium and renal veins, are more frequently seen than arterial thromboses. A stroke may be caused by the occlusion of the arterial flow entering the brain or by occlusion of its venous drainage system...
April 2016: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/27019251/-in-process-citation
#10
María D Ballesteros Pomar, Alfonso Suárez Gutiérrez, Alicia Calleja Fernández, Begoña Pintor de la Maza, Ana Urioste Fondo, Alfonso Vidal Casariego, Rocío Villar Taibo, Concepción Otero Redondo, Manuel Herrero Moratiel, Isidoro Cano Rodríguez, Juan Luis Burón Llamazares
Introducción: la desnutrición relacionada con la enfermedad (DRE) afecta al menos a una cuarta parte de los pacientes hospitalizados, aumentando la morbimortalidad del paciente durante su hospitalización y al alta. Sin embargo, su repercusión en la actividad hospitalaria no está bien cuantificada.Objetivo: determinar el impacto de una adecuada codificación de la DRE y los procedimientos empleados para revertirla en el peso medio del hospital y otros índices hospitalarios.Material y métodos: estudio comparativo realizado en todos los pacientes subsidiarios de soporte nutricional artificial seguidos por la Unidad de Nutrición Clínica y Dietética de la Sección de Endocrinología y Nutrición (UNCyD-SEyN) del Complejo Asistencial Universitario de León durante los años 2008 y 2013...
2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/26969776/guidelines-on-the-treatment-of-acute-myeloid-leukemia-associa%C3%A3-%C3%A3-o-brasileira-de-hematologia-hemoterapia-e-terapia-celular-project-guidelines-associa%C3%A3-%C3%A3-o-m%C3%A3-dica-brasileira-2015
#11
Rosane Bittencourt, Teresa Cristina Bortolheiro, Maria de Lourdes Lopes Ferrari Chauffaille, Evandro Maranhão Fagundes, Katia Borgia Barbosa Pagnano, Eduardo Magalhães Rego, Wanderley Marques Bernardo
No abstract text is available yet for this article.
January 2016: Revista Brasileira de Hematologia e Hemoterapia
https://www.readbyqxmd.com/read/26546167/-comparability-study-of-analytical-results-between-a-group-of-clinical-laboratories
#12
A Alsius-Serra, M Ballbé-Anglada, M L López-Yeste, M Buxeda-Figuerola, E Guillén-Campuzano, L Juan-Pereira, C Colomé-Mallolas, I Caballé-Martín
OBJECTIVE: To describe the study of the comparability of the measurements levels of biological tests processed in biochemistry in Catlab's 4 laboratories. MATERIAL AND METHODS: Quality requirements, coefficients of variation and total error (CV% and TE %) were established. Controls were verified with the precision requirements (CV%) in each test and each individual laboratory analyser. Fresh serum samples were used for the comparability study. The differences were analysed using a Microsoft Access® application that produces modified Bland-Altman plots...
November 2015: Revista de Calidad Asistencial: Organo de la Sociedad Española de Calidad Asistencial
https://www.readbyqxmd.com/read/25938844/health-related-quality-of-life-in-leukemia-survivors-of-allogeneic-hematopoietic-stem-cell-transplantation-employing-the-mexican-reduced-intensity-conditioning
#13
Mónica P González-Ramírez, Karla Miravete-Lagunes, Andrés Gómez-de-León, Sergio Ponce-de-León, Andrea P Tenorio-Rojo, Nora A Martagón-Herrera, Jesús A Hernández-Reyes, Arturo García-Villasenor, Esteban Burguette, María Fernanda Vallejo-Villalobos, Guillermo J Ruiz-Delgado, David Gómez-Almaguer, Guillermo J Ruiz-Argüelles
BACKGROUND: Quality of life (QOL) is an important consideration in the counseling, implementation, and post-treatment management of arduous treatments for life-threatening conditions such as allogeneic hematopoietic cell transplantation (allo-HCT). OBJECTIVE: To analyze the QOL of leukemia patients allografted with the Mexican reduced-intensity conditioning regimen in two Mexican academic medical centers. MATERIAL AND METHODS: By means of the quality metric short form 36 version 2 to measure generic health concepts, relevant QOL was analyzed in leukemia patients who underwent allo-HCT using reduced-intensity conditioning on an outpatient basis at either the Centro de Hematología y Medicina Interna de Puebla of the Clínica Ruiz or the Hematology Service of the Internal Medicine Department of the Hospital "Dr...
March 2015: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/25925695/outcome-of-recipients-of-hematopoietic-stem-cell-transplants-who-require-intensive-care-unit-support-a-single-institution-experience
#14
Samantha Galindo-Becerra, Nancy Labastida-Mercado, Jaime Rosales-Padrón, Jessica García-Chavez, Elena Soto-Vega, Liliana Rivadeneyra-Espinoza, Andres A León-Peña, Danitza Fernández-Lara, Monica Dominguez-Cid, Javier Anthon-Méndez, Daniel Arizpe-Bravo, Guillermo J Ruiz-Delgado, Guillermo J Ruiz-Argüelles
Admission to the intensive care unit (ICU) of a patient who has been grafted with hematopoietic stem cells is a serious event, but the role of the ICU in this setting remains controversial. Data were analyzed from patients who underwent autologous or allogeneic bone marrow transplantation at the Centro de Hematología y Medicina Interna de Puebla, México, between May 1993 and October 2014. In total, 339 patients were grafted: 150 autografts and 189 allografts; 68 of the grafted patients (20%) were admitted to the ICU after transplantation: 27% of the allografted and 11% of the autografted patients (p = 0...
2015: Acta Haematologica
https://www.readbyqxmd.com/read/25727830/-hereditary-spherocytosis-review-part-ii-symptomatology-outcome-complications-and-treatment
#15
Hugo Donato, Renée Leonor Crisp, María Cristina Rapetti, Eliana García, Myriam Attie
Hereditary spherocytosis must always be suspected in children with anemia, hyperbilirubinemia, splenomegaly or cholelithiasis, in the asymptomatic individual with an affected relative, and in the neonate with hyperbilirubinemia with no blood group incompatibility; its early detection is key to avoid kernicterus. Follow-up of these patients is based on periodical control and supply of information on the adequate management of hemolytic or aplastic crisis, and early detection of cholelithiasis. The decision to perform splenectomy is usually associated with quality of life rather than life-threatening risk, and it should result from a consensus between patient, parents and physicians...
April 2015: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/25680074/acute-myeloid-leukemia-with-inv-3-q21q26-2-or-t-3-3-q21-q26-2-clinical-and-biological-features-and-comparison-with-other-acute-myeloid-leukemias-with-cytogenetic-aberrations-involving-long-arm-of-chromosome-3
#16
Jose Maria Raya, Taida Martín-Santos, Elisa Luño, Carmen Sanzo, Maria Luz Perez-Sirvent, Esperanza Such, José Tomás Navarro, Fuensanta Millá, Esther Alonso, Alicia Domingo, María Rozman, Marina Díaz-Beva, Ana Batlle, Sonia González-de-Villambrosia, Esperanza Tuset, Teresa Vallespí, Margarita Ortega, Alfredo Bermejo, Marisa Martín-Ramos, Valeria Peri, Francesc Solé, Lourdes Florensa
Objectives To compare, from a biological and clinical perspective, a significant group of patients with AML with inv(3)(q21q26.2) or t(3;3)(q21;q26.2) with another group of AML carrying different abnormalities of 3q at q21 or q26, the latter named as the AML abn(3q) group. Methods We developed a national survey with the participation of 13 Spanish hospitals, and retrospectively reviewed (from 1990 to 2010) these subtypes of AML. Fifty-five patients were collected: 35 with AML inv(3)/t(3;3) and 20 with AML abn(3q)...
February 13, 2015: Hematology (Amsterdam, Netherlands)
https://www.readbyqxmd.com/read/25638757/many-thanks-to-our-eternal-editor-of-the-revista-brasileira-de-hematologia-e-hemoterapia-professor-milton-artur-ruiz
#17
Cármino Antonio de Souza
No abstract text is available yet for this article.
January 2015: Revista Brasileira de Hematologia e Hemoterapia
https://www.readbyqxmd.com/read/25627885/is-sickle-cell-anemia-a-risk-factor-for-severe-dental-malocclusion
#18
Cyrene Piazera Silva Costa, Halinna Larissa Cruz Correa Carvalho, Soraia de Fátima Carvalho Souza, Erika Bárbara Abreu Fonseca Thomaz
The aim of this study was to investigate possible associations between sickle cell anemia (SCA) and the severity of dental malocclusion (MO). This was a retrospective cohort study of 93 individuals with SCA (G1) and 186 individuals without the disease (G2). SCA patients were randomly selected by a simple draw from patients treated in the Centro de Hematologia e Hemoterapia do Maranhão (HEMOMAR) in northeastern Brazil. Patients aged between 16 and 60 were included after being tested for the hemoglobin S gene...
2015: Brazilian Oral Research
https://www.readbyqxmd.com/read/25622164/-hereditary-spherocytosis-review-part-i-history-demographics-pathogenesis-and-diagnosis
#19
Hugo Donato, Renée Leonor Crisp, María Cristina Rapetti, Eliana García, Myriam Attie
Hereditary spherocytosis is the most frequent hereditary anemia excluding beta thalassemia in Argentina. Historical, demographic, genetic and pathogenic aspects of the disease are reviewed, and confirmatory laboratory tests are described. Special characteristics on the outcome of the disease in our population and prevalent protein deficiencies in our country are described. Emphasis is given on new available laboratory tests, which allow an earlier diagnosis using volume of blood samples significantly smaller than required for conventional tests...
January 2015: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/25568763/late-differentiation-syndrome-in-acute-promyelocytic-leukemia-a-challenging-diagnosis
#20
Renata Cabral, Juan Carlos Caballero, Sara Alonso, Julio Dávila, Monica Cabrero, Dolores Caballero, Lourdes Vázquez, Fermin Sánchez-Guijo, Lucia López, Maria C Cañizo, Maria V Mateos, Marcos González
Detailed knowledge about differentiation syndrome (DS) has remained limited. There are 2 large studies conducted by the Spanish workgroup PETHEMA (Programa Español de Tratamientos en Hematología; Spanish Program on Hematology Treatments) and the European group trial (LPA 96-99 and APL 93) in which the incidence, characteristics, prognostic factors and outcome of patients developing DS are evaluated. Both have described the median time of DS development between 10 and 12 days. The severity of the DS has been evaluated in the study conducted by PETHEMA, and severe DS usually occurs at the beginning of the treatment (median of 6 days), as compared with moderate DS (median of 15 days)...
November 19, 2014: Hematology Reports
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