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https://www.readbyqxmd.com/read/29786151/time-dependent-loss-of-trabecular-bone-in-human-tibial-plateau-fractures
#1
Lucian Bogdan Solomon, David Kitchen, Paul Hamill Anderson, Dongqing Yang, Yolandi Starczak, Masakazu Kogawa, Egon Perilli, Peter Jonathan Smitham, Mark Sean Rickman, Dominic Thewlis, Gerald James Atkins
We investigated if time between injury and surgery affects cancellous bone properties in patients suffering tibial plateau fractures (TPF), in terms of structural integrity and gene expression controlling bone loss. A cohort of 29 TPF, operated 1-17 days post-injury, had biopsies from the fracture and an equivalent contralateral limb site, at surgery. Samples were assessed using micro-computed tomography and real-time RT-PCR analysis for the expression of genes known to be involved in bone remodeling and fracture healing...
May 22, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29786044/prognostic-value-of-model-for-end-stage-liver-disease-incorporating-with-serum-sodium-score-for-development-of-acute-kidney-injury-after-liver-transplantation
#2
Yuan Cheng, Guo-Qing Wei, Qiu-Cheng Cai, Yi Jiang, Ai-Ping Wu
Background: Contribution of model for end-stage liver disease incorporating with serum sodium (MELD-Na) score in predicting acute kidney injury (AKI) after orthotopic liver transplantation (OLT) is yet to be identified. This study assessed the prognostic value of MELD-Na score for the development of AKI following OLT. Methods: Preoperative and surgery-related variables of 321 adult end-stage liver disease patients who underwent OLT in Fuzhou General Hospital were collected...
June 5, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29785991/all-india-ophthalmological-society-members-survey-results-cataract-surgery-antibiotic-prophylaxis-current-practice-pattern-2017
#3
Prafulla Kumar Maharana, Jay K Chhablani, Tara Prasad Das, Atul Kumar, Namrata Sharma
Purpose: The purpose of this article is to document the current practice pattern of Indian ophthalmologists for antibiotic prophylaxis in cataract surgery to prevent endophthalmitis. Methods: Fifteen structured questions were sent online to all ophthalmologists registered with the All India Ophthalmological Society. The questionnaire was divided into three main categories of prophylaxis - preoperative, intraoperative, and postoperative. A web-based anonymous survey was conducted, and a unique response link allowed completing the survey only once...
June 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29785720/mobility-scores-as-a-predictor-of-length-of-stay-in-general-surgery-a-prospective-cohort-study
#4
Georgia M Carroll, Jacob Hampton, Rosemary Carroll, Stephen R Smith
BACKGROUND: Post-operative length of stay (LOS) is an increasingly important clinical indicator in general surgery. Despite this, no tool has been validated to predict LOS or readiness for discharge in general surgical patients. The de Morton Mobility Index (DEMMI) is a functional mobility assessment tool that has been validated in rehabilitation patient populations. In this prospective cohort study, we aimed to identify if trends in DEMMI scores were associated with discharge within 1 week and overall LOS in general surgical patients...
May 22, 2018: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29785458/high-resolution-standardization-reduces-delay-due-to-workflow-disruptions-in-laparoscopic-cholecystectomy
#5
Marco von Strauss Und Torney, Sohelia Aghlmandi, Jasmin Zeindler, Debora Nowakowski, Christian A Nebiker, Christoph Kettelhack, Rachel Rosenthal, Raoul A Droeser, Savas D Soysal, Henry Hoffmann, Robert Mechera
BACKGROUND: Optimal resource utilization in high-cost environments like operating theatres is fundamental in today's cost constrained health care systems. Interruptions of the surgical workflow, i.e. microcomplications (MC), lead to prolonged procedure times and higher costs and can be indicative of surgical mistakes. Reducing MC can improve operating room efficiency and prevent intraoperative complications. We, therefore, aimed to evaluate the impact of a high-resolution standardized laparoscopic cholecystectomy protocol (HRSL) on operative time and intraoperative interruptions in a teaching hospital...
May 21, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29785292/thoracoscopic-stapler-based-bidirectional-segmentectomy-for-posterior-basal-segment-s10-and-its-variants
#6
Masaaki Sato, Tomonori Murayama, Jun Nakajima
Thoracoscopic segmentectomy for the posterior basal segment (S10) and its variant (e.g., S9+10 and S10b+c combined subsegmentectomy) is one of the most challenging anatomical segmentectomies. Stapler-based segmentectomy is attractive to simplify the operation and to prevent post-operative air leakage. However, this approach makes thoracoscopic S10 segmentectomy even more tricky. The challenges are caused mostly from the following three reasons: first, similar to other basal segments, "three-dimensional" stapling is needed to fold a cuboidal segment; second, the belonging pulmonary artery is not directly facing the interlobar fissure or the hilum, making identification of target artery difficult; third, the anatomy of S10 and adjacent segments such as superior (S6) and medial basal (S7) is variable...
April 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29785227/alterations-in-the-three-components-of-selfhood-in-persons-with-post-traumatic-stress-disorder-symptoms-a-pilot-qeeg-neuroimaging-study
#7
Andrew A Fingelkurts, Alexander A Fingelkurts
Background and Objective: Understanding how trauma impacts the self-structure of individuals suffering from the Post-Traumatic Stress Disorder (PTSD) symptoms is a complex matter and despite several attempts to explain the relationship between trauma and the "Self", this issue still lacks clarity. Therefore, adopting a new theoretical perspective may help understand PTSD deeper and to shed light on the underlying psychophysiological mechanisms. Methods: In this study, we employed the "three-dimensional construct model of the experiential selfhood" where three major components of selfhood (phenomenal first-person agency, embodiment, and reflection/narration) are related to three Operational Modules (OMs) of the self-referential brain network...
2018: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/29785163/management-of-intrinsic-discoloration-using-walking-bleach-technique-in-maxillary-central-incisors
#8
Sanket Hans Pandey, Pallav Mahesh Patni, Pradeep Jain, Arpita Chaturvedi
Introduction: Non-vital bleaching is a non-invasive technique to treat the intrinsic discoloration of teeth of several etiologies. Hydrogen peroxide and sodium perborate are commonly used bleaching agents. Aim: The aim of this case report is to demonstrate the non-vital bleaching technique in maxillary anterior teeth. Method: Maxillary central incisors were isolated with rubber dam and root canal treatment was performed. Barrier space preparation was done using a heated instrument...
2018: Clujul Medical (1957)
https://www.readbyqxmd.com/read/29785158/obtaining-adequate-surgical-margin-status-in-breast-conservation-therapy-intraoperative-ultrasound-guided-resection-versus-specimen-mammography
#9
Maria Mihaela Pop, Silviu Cristian, Orsolya Hanko-Bauer, Dana Valentina Ghiga, Rares Georgescu
Background and aim: The purpose of breast-conserving surgery (BCS) for women with cancer is to perform an oncological radical procedure with disease-free margins at the final histological assessment and with the best aesthetic result possible. Intraoperative resected specimen ultrasound and intraoperative resected specimen mammography may reduce the rates of positive margins and reexcision among patients undergoing conserving therapy. Our objective is to compare the two methods with the histopathological results for a preset cut off and asses which parameters can influence the positive margin status...
2018: Clujul Medical (1957)
https://www.readbyqxmd.com/read/29784455/incidence-and-risk-factors-associated-with-30-day-post-operative-venous-thromboembolism-a-nsqip-pediatric-analysis
#10
Jennifer J Ahn, Paul A Merguerian, Margarett Shnorhavorian
INTRO: Venous thromboembolism (VTE) is a rare event in children, but can cause significant morbidity and mortality. The majority of research on pediatric VTE has been in the trauma and critical care populations. The incidence of VTE after surgery in children is not well-established. OBJECTIVE: The objective was to evaluate the incidence of VTE in the 30 days after surgery, as well as associated risk factors. STUDY DESIGN: All cases in the National Surgical Quality Improvement Program Pediatric (NSQIPP) database from 2012 to 2015 were assessed for presence of post-operative VTE...
May 8, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29784055/usefulness-of-c-reactive-protein-and-serum-amyloid-a-in-early-detection-of-postoperative-infectious-complications-to-tibial-plateau-leveling-osteotomy-in-dogs
#11
Karin Löfqvist, Mads Kjelgaard-Hansen, Michelle Brønniche Møller Nielsen
BACKGROUND: Cranial cruciate ligament rupture is a prevalent injury in dogs, and tibial plateau leveling osteotomy (TPLO) is one of the preferred surgical techniques. Surgical site infection is a possible complication following TPLO and measurement of serum acute phase proteins is suggested to be a way to early recognize and distinguish postoperative infectious complications from normal postoperative inflammatory conditions. In this study we investigate the changes in concentrations of the systemic inflammatory markers C-reactive protein (CRP) and serum amyloid A (SAA) following tibial plateau leveling osteotomy (TPLO) in dogs and evaluate if deviations from the changes expectedly induced by the surgical procedure are useful in early detection of post-surgical infections...
May 21, 2018: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/29783184/postoperative-outcomes-in-patients-with-a-do-not-resuscitate-dnr-order-undergoing-elective-procedures
#12
Ethan Y Brovman, Elisa C Walsh, Brittany N Burton, Christine E Kuo, Charlotta Lindvall, Rodney A Gabriel, Richard D Urman
STUDY OBJECTIVE: Do-not-resuscitate (DNR) status has been shown to be an independent risk factor for mortality in the post-operative period. Patients with DNR orders often undergo elective surgeries to alleviate symptoms and improve quality of life, but there are limited data on outcomes for informed decision making. DESIGN: Retrospective cohort study. SETTING: A multi-institutional setting including operating room, postoperative recovery area, inpatient wards, and the intensive care unit...
May 18, 2018: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/29783010/translaminar-approach-for-treatment-of-hidden-zone-foraminal-lumbar-disc-herniations-considerations-on-the-surgical-technique-and-pre-operative-selection-of-patients-with-a-long-term-follow-up
#13
Christian Cossandi, Andrea Fanti, Andrea Gerosa, Andrea Bianco, Riccardo Fornaro, Emanuela Crobeddu, Sara Forgnone, Gabriele Panzarasa, Andrea Di Cristofori
BACKGROUND: Lumbar disc herniation (LDH) is a common degenerative disease of the lumbar spine with a prevalence of 1-3% in population studies according to some authors. In 10% of patients there is a fragment migrated cranially in the Macnab's "hidden zone". In selected cases, this fragment can be removed with a translaminar approach that has been described in 1998. Aim of our work is to provide a detailed description of the technical advantages and pitfalls of such approach reviewing a consecutive series of patients...
May 18, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29782887/endoscopic-injection-of-low-dose-triamcinolone-a-simple-minimally-invasive-and-effective-therapy-for-interstitial-cystitis-with-hunner-lesions
#14
Michael G Funaro, Alexandra N King, Joel N H Stern, Robert M Moldwin, Sonia Bahlani
OBJECTIVES: To investigate the efficacy of low dose triamcinolone injection for effectiveness and durability in interstitial cystitis/bladder pain syndrome (IC/BPS) patients with Hunner Lesions (HL). MATERIALS & METHODS: Clinical data from patients with HL who underwent endoscopic submucosal injection of triamcinolone were reviewed: Demographics, pre/post operative pain and nocturia scores, and long-term clinical outcomes were assessed. Duration of response was estimated by time to repeat procedure...
May 18, 2018: Urology
https://www.readbyqxmd.com/read/29782862/evaluation-of-cardiac-arrhythmic-risks-using-a-rabbit-model-of-left-ventricular-systolic-dysfunction
#15
Bianca Hemmeryckx, Yuanbo Feng, Liesbeth Frederix, Marleen Lox, Sander Trenson, Rob Vreeken, Hua Rong Lu, David Gallacher, Yicheng Ni, H Roger Lijnen
Patients with heart disease have a higher risk to develop cardiac arrhythmias, either spontaneously or drug-induced. In this study, we have used a rabbit model of myocardial infarction (MI) with severe left ventricular systolic dysfunction (LVSD) to study potential drug-induced cardiac risks with N-(piperidin-2-ylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (flecainide). Upon ligation of the left circumflex arteries, male New Zealand White rabbits developed a large MI and moderate or severe LVSD 7 weeks after surgery, in comparison to SHAM-operated animals...
May 18, 2018: European Journal of Pharmacology
https://www.readbyqxmd.com/read/29782820/onchocerciasis-prevalence-human-migration-and-risks-for-onchocerciasis-elimination-in-the-upper-mouhoun-nakamb%C3%A3-and-nazinon-river-basins-in-burkina-faso
#16
Achille S Nikièma, Lassane Koala, Rory J Post, Alain B Paré, Claude Montant Kafando, François Drabo, Adrien M G Belem, Roch K Dabiré, Soungalo Traoré
Historically, the whole of Burkina Faso was considered to be endemic for onchocerciasis (except a small area in the far north of the country) with prevalence rates 60-80%, but all endemic areas were included in the World Health Organisation Onchocerciasis Control Programme, which operated a system of vector control by larviciding beginning in 1974. In Burkina Faso larviciding had been phased out by 1989 when it was considered that onchocerciasis had been reduced to levels below the transmission breakpoint (and any residual infections would disappear without further intervention)...
May 18, 2018: Acta Tropica
https://www.readbyqxmd.com/read/29782655/cross-scale-occupancy-dynamics-of-a-post-fire-specialist-in-response-to-variation-across-a-fire-regime
#17
Morgan W Tingley, Andrew N Stillman, Robert L Wilkerson, Christine A Howell, Sarah C Sawyer, Rodney B Siegel
1.Fire creates challenges and opportunities for wildlife through rapid destruction, modification, and creation of habitat. Fire has spatially variable effects on landscapes, however, and for species that benefit from the ephemeral resource patches created by fire, it is critical to understand characteristics of fires that promote post-fire colonization and persistence, and the spatial scales on which they operate. 2.Using a model post-fire specialist, the black-backed woodpecker (Picoides arcticus), we examined how colonization and persistence varied across two spatial scales as a function of four characteristics of fire regimes - fire severity, fire size, fire ignition date, and number of years since fire...
May 21, 2018: Journal of Animal Ecology
https://www.readbyqxmd.com/read/29782566/post-operative-radiation-therapy-in-locally-advanced-non-small-cell-lung-cancer-and-the-impact-of-sequential-versus-concurrent-chemotherapy
#18
EDITORIAL
Mark R Waddle, Stephen Ko, Margaret M Johnson, Yanyan Lou, Robert C Miller, Anna C Harrell, Daniel M Trifiletti
No abstract text is available yet for this article.
April 2018: Translational Lung Cancer Research
https://www.readbyqxmd.com/read/29782500/the-human-snail-transmission-environment-shapes-long-term-schistosomiasis-control-outcomes-implications-for-improving-the-accuracy-of-predictive-modeling
#19
David Gurarie, Nathan C Lo, Martial L Ndeffo-Mbah, David P Durham, Charles H King
INTRODUCTION: Schistosomiasis is a chronic parasitic trematode disease that affects over 240 million people worldwide. The Schistosoma lifecycle is complex, involving transmission via specific intermediate-host freshwater snails. Predictive mathematical models of Schistosoma transmission have often chosen to simplify or ignore the details of environmental human-snail interaction in their analyses. Schistosome transmission models now aim to provide better precision for policy planning of elimination of transmission...
May 21, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29782440/management-for-simultaneous-patella-tendon-and-anterior-cruciate-ligament-ruptures-a-systematic-review-of-available-literature
#20
Alexander Handel Matthews, Ethan James Fraser, Benjamin Parkinson
BACKGROUND: Combined rupture of the anterior cruciate ligament (ACL) and patella tendon (PT) is a rare injury pattern. Currently little evidence exists to help guide management decisions for these patients. METHODS: A systematic literature search was conducted using PubMed (MEDLINE) and Scopus (EMBASE, MEDLINE) for all articles reporting on combined rupture of the anterior cruciate ligament (ACL) and patella tendon (PT). The characteristic injury mechanisms, common presentation findings and outcomes of simultaneous and staged treatment strategies were determined to provide guidance for the management of this uncommon injury pattern...
May 15, 2018: Journal of Orthopaedic Trauma
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