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https://www.readbyqxmd.com/read/28337411/physiological-and-pathological-high-frequency-oscillations-have-distinct-sleep-homeostatic-properties
#1
Nicolás von Ellenrieder, François Dubeau, Jean Gotman, Birgit Frauscher
OBJECTIVE: The stage of sleep is a known modulator of high-frequency oscillations (HFOs). For instance, high amplitude slow waves during NREM sleep and the subtypes of REM sleep were shown to contribute to a better separation between physiological and pathological HFOs. This study investigated rates and spatial spread of the different HFO types (physiological and pathological ripples in the 80-250 Hz frequency band, and fast ripples above 250 Hz) depending on time spent in sleep across the different sleep cycles...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28334175/attenuated-fast-steady-state-visual-evoked-potentials-during-human-sleep
#2
Omer Sharon, Yuval Nir
During sleep, external sensory events rarely elicit a behavioral response or affect perception. However, how sensory processing differs between wakefulness and sleep remains unclear. A major difficulty in this field stems from using brief auditory stimuli that often trigger nonspecific high-amplitude "K-complex" responses and complicate interpretation. To overcome this challenge, here we delivered periodic visual flicker stimulation across sleep and wakefulness while recording high-density electroencephalography (EEG) in humans...
February 25, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28330957/neurodegeneration-in-rem-sleep-behavior-disorder-stratification-keeps-improving
#3
Ronald B Postuma, Claudia Trenkwalder
No abstract text is available yet for this article.
March 22, 2017: Neurology
https://www.readbyqxmd.com/read/28330956/predictive-markers-for-early-conversion-of-irbd-to-neurodegenerative-synucleinopathy-diseases
#4
Yuanyuan Li, Wenyan Kang, Qiong Yang, Lina Zhang, Linyuan Zhang, Fangyi Dong, Shengdi Chen, Jun Liu
OBJECTIVE: To determine the predictive value of clinical assessment and dopamine transporter (DAT) uptake for the early development of neurodegenerative synucleinopathy diseases from idiopathic REM sleep behavior disorder (iRBD) over 5 years in a Chinese population. METHODS: Forty-three patients with iRBD were administered clinical assessment tests, and 35 were examined by DAT-SPECT imaging during 2011. Cox proportional hazard and Kaplan-Meier analyses were used to evaluate the predictive value of the markers in a follow-up study over 5 years...
March 22, 2017: Neurology
https://www.readbyqxmd.com/read/28329386/eeg-changes-accompanying-successive-cycles-of-sleep-restriction-with-and-without-naps-in-adolescents
#5
Ju Lynn Ong, June C Lo, Joshua J Gooley, Michael W L Chee
Study Objectives: To investigate the temporal evolution of sleep EEG changes in adolescents across two cycles of sleep restriction and recovery simulating an intense school week and to examine the effect of an afternoon nap on nocturnal sleep. Methods: A parallel-group design, quasi-laboratory study was conducted in a student hostel. Fifty-seven adolescents (31 males, age=15-19y) were randomly assigned to nap or no nap groups. Participants underwent a 15-day protocol comprising two sleep restriction (5h time-in-bed) and recovery (9h time-in-bed) cycles...
March 3, 2017: Sleep
https://www.readbyqxmd.com/read/28329381/the-effects-of-an-afternoon-nap-on-episodic-memory-in-young-and-older-adults-napping-and-aging
#6
Michael K Scullin, Jacqueline Fairley, Michael J Decker, Donald L Bliwise
Study Objectives: In young adults, napping is hypothesized to benefit episodic memory retention (e.g., via consolidation). Whether this relationship is present in older adults has not been adequately tested, but is an important question because older adults display marked changes in sleep and memory. Design: Between-subjects design. Setting: Sleep laboratory at Emory University School of Medicine. Participants: 50 healthy young adults (18-29) and 45 community dwelling older adults (58-83)...
March 1, 2017: Sleep
https://www.readbyqxmd.com/read/28329332/excessive-daytime-sleepiness-predicts-neurodegeneration-in-idiopathic-rem-sleep-behavior-disorder
#7
Junying Zhou, Jihui Zhang, Siu Ping Lam, Joey Wy Chan, Vincent Mok, Anne Chan, Shirley Xin Li, Yaping Liu, Xiangdong Tang, Wing Ho Yung, Yun Kwok Wing
Study Objectives: To determine the association of excessive daytime sleepiness (EDS) with the conversion of neurodegenerative diseases in patients with idiopathic REM sleep behavior disorder (iRBD). Methods: A total of 179 patients with iRBD (79.1% males, mean age = 66.3 ± 9.8 years) were consecutively recruited. Forty-five patients with Epworth Sleepiness Scale score ≥ 14 were defined as having EDS. Demographic, clinical and polysomnographic data were compared between iRBD patients with and without EDS...
March 16, 2017: Sleep
https://www.readbyqxmd.com/read/28329204/new-neuroscience-tools-that-are-identifying-the-sleep-wake-circuit
#8
Priyattam J Shiromani, John H Peever
The complexity of the brain is yielding to technology. In the area of sleep neurobiology, conventional neuroscience tools such as lesions, cell recordings, c-Fos, and axon-tracing methodologies have been instrumental in identifying the complex and intermingled populations of sleep- and arousal-promoting neurons that orchestrate and generate wakefulness, NREM, and REM sleep. In the last decade, new technologies such as optogenetics, chemogenetics and the CRISPR-Cas system have begun to transform how biologists understand the finer details associated with sleep-wake regulation...
March 1, 2017: Sleep
https://www.readbyqxmd.com/read/28329117/muscle-activity-during-sleep-in-human-subjects-rats-and-mice-towards-translational-models-of-rem-sleep-without-atonia
#9
Alessandro Silvani, Raffaele Ferri, Viviana Lo Martire, Stefano Bastianini, Chiara Berteotti, Agnese Salvadè, Giuseppe Plazzi, Marco Zucconi, Luigi Ferini-Strambi, Claudio L Bassetti, Mauro Manconi, Giovanna Zoccoli
Study Objectives: rapid-eye-movement (REM) sleep without atonia (RSWA) is a marker of REM sleep behavior disorder (RBD) and is common in narcolepsy. Available techniques for electromyogram (EMG) analysis are species-specific, limiting translational research on RSWA. We developed an automated technique based on distributions of normalized EMG values (DNE) to overcome this limitation. With DNE, we tested whether the control of neck and tibialis anterior (TA) muscles during sleep in wild-type rats and mice validly models the control of submentalis (chin) and TA muscles in healthy humans...
February 22, 2017: Sleep
https://www.readbyqxmd.com/read/28328536/neurotransmission-systems-in-parkinson-s-disease
#10
Hossein Sanjari Moghaddam, Ameneh Zare-Shahabadi, Farzaneh Rahmani, Nima Rezaei
Parkinson's disease (PD) is histologically characterized by the accumulation of α-synuclein particles, known as Lewy bodies. The second most common neurodegenerative disorder, PD is widely known because of the typical motor manifestations of active tremor, rigidity, and postural instability, while several prodromal non-motor symptoms including REM sleep behavior disorders, depression, autonomic disturbances, and cognitive decline are being more extensively recognized. Motor symptoms most commonly arise from synucleinopathy of nigrostriatal pathway...
March 22, 2017: Reviews in the Neurosciences
https://www.readbyqxmd.com/read/28326309/space-allowance-of-the-littered-area-affects-lying-behavior-in-group-housed-horses
#11
Joan-Bryce Burla, Christina Rufener, Iris Bachmann, Lorenz Gygax, Antonia Patt, Edna Hillmann
Horses can sleep while standing; however, recumbency is required for rapid eye movement (REM) sleep and therefore essential. Previous research indicated a minimal duration of recumbency of 30 min per 24 h to perform a minimal duration of REM sleep. For group-housed horses, suitable lying area represents a potentially limited resource. In Switzerland, minimal dimensions for the space allowance of the littered area are therefore legally required. To assess the effect of different space allowances of the littered area on lying behavior, 38 horses in 8 groups were exposed to 4 treatments for 11 days each; T0: no litter provided, T0...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28326118/spectral-analysis-of-polysomnography-in-narcolepsy
#12
Seok Ho Yun, Ho Dong Choi, Wan Seok Seo
OBJECTIVE: This study was conducted to identify differences between people with narcolepsy and the normal control of delta and theta activity using electroencephalogram (EEG) spectrum analysis of nocturnal polysomnography (PSG). METHODS: Seven narcolepsy patients and seven age-sex matched normal controls underwent PSG and multiple sleep latency tests. Participants' non-rapid eye movement (NREM) sleep EEGs in PSG was analyzed using a Fast Fourier Transform technique...
March 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/28326036/associations-between-early-markers-of-parkinson-s-disease-and-sarcopenia
#13
Michael Drey, Sandra E Hasmann, Jan-Peter Krenovsky, Markus A Hobert, Stefanie Straub, Morad Elshehabi, Anna-Katharina von Thaler, Andreas J Fallgatter, Gerhard W Eschweiler, Ulrike Suenkel, Daniela Berg, Walter Maetzler
Introduction: Sarcopenia and Parkinson's disease (PD) are both common age-related syndromes, and there is preliminary evidence that the probability of the co-occurrence of these syndromes within one individual is higher than expected. However, it is unclear to date whether one of the syndromes induces the other, or whether there may be common underlying causes. This pilot study thus aimed at investigating the association of the features of increased risk for PD with early stage sarcopenia (ESS). Method: Two hundred and fifty-five community-dwelling individuals were recruited from the Tübinger evaluation of Risk factors for Early detection of NeuroDegeneration (TREND) study...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28325016/sleep-stage-classification-by-non-contact-vital-signs-indices-using-doppler-radar-sensors
#14
Masayuki Kagawa, Kazuki Suzumura, Takemi Matsui
Disturbed sleep has become more common in recent years. To improve the quality of sleep, undergoing sleep observation has gained interest as a means to resolve possible problems. In this paper, we evaluate a non-restrictive and non-contact method for classifying real-time sleep stages and report on its potential applications. The proposed system measures heart rate (HR), heart rate variability (HRV), body movements, and respiratory signals of a sleeping person using two 24-GHz microwave radars placed beneath the mattress...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324987/sleep-architecture-measurement-based-on-cardiorespiratory-parameters
#15
Alexander Tataraidze, Lyudmila Korostovtseva, Lesya Anishchenko, Mikhail Bochkarev, Yurii Sviryaev
This paper presents a method for the detection of wakeful state, rapid eye movement sleep (REM), light sleep (N1&N2) and deep sleep (N3&N4) based on cardiorespiratory parameters. Experiments were conducted with data of 625 subjects without sleep-disordered breathing selected from the SHHS dataset. Compared to previous studies, our method considers results of neighboring epochs classification and epoch position over record time. The method demonstrates Cohen's kappa of 0.57 ± 0.13 and the accuracy of 71.4 ± 8...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28323455/the-sleep-of-the-ring-comparison-of-the-%C3%A5-ura-sleep-tracker-against-polysomnography
#16
Massimiliano de Zambotti, Leonardo Rosas, Ian M Colrain, Fiona C Baker
OBJECTIVE/BACKGROUND: To evaluate the performance of a multisensor sleep-tracker (ŌURA ring) against polysomnography (PSG) in measuring sleep and sleep stages. PARTICIPANTS: Forty-one healthy adolescents and young adults (13 females; Age: 17.2 ± 2.4 years). METHODS: Sleep data were recorded using the ŌURA ring and standard PSG on a single laboratory overnight. Metrics were compared using Bland-Altman plots and epoch-by-epoch (EBE) analysis...
March 21, 2017: Behavioral Sleep Medicine
https://www.readbyqxmd.com/read/28322726/rem-sleep-behavior-disorder-a-review-of-the-literature-and-update-on-current-concepts
#17
REVIEW
Carlos L Rodriguez, Nattapong Jaimchariyatam, Kumar Budur
No abstract text is available yet for this article.
March 16, 2017: Chest
https://www.readbyqxmd.com/read/28316568/towards-a-functional-understanding-of-pgo-waves
#18
REVIEW
Jarrod A Gott, David T J Liley, J Allan Hobson
Ponto-Geniculo-Occipital (PGO) waves are biphasic field potentials identified in a range of mammalian species that are ubiquitous with sleep, but can also be identified in waking perception and eye movement. Their role in REM sleep and visual perception more broadly may constitute a promising avenue for further research, however what was once an active field of study has recently fallen into stasis. With the reality that invasive recordings performed on animals cannot be replicated in humans; while animals themselves cannot convey experience to the extent required to elucidate how PGO waves factor into awareness and behavior, innovative solutions are required if significant research outcomes are to ever be realized...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28315846/risk-factors-for-early-psychosis-in-pd-insights-from-the-parkinson-s-progression-markers-initiative
#19
Dominic H Ffytche, Joana B Pereira, Clive Ballard, K Ray Chaudhuri, Daniel Weintraub, Dag Aarsland
BACKGROUND: Parkinson's Disease (PD) psychosis refers to the spectrum of illusions, formed hallucinations and delusions that occur in PD. Visual hallucinations and illusions are thought to be caused by specific cognitive and higher visual function deficits and patients who develop such symptoms early in the disease course have greater rates of cognitive decline and progression to dementia. To date, no studies have investigated whether such deficits are found prior to the onset of PD psychosis...
April 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28315757/chronic-social-stress-leads-to-altered-sleep-homeostasis-in-mice
#20
Nadja Olini, Iru Rothfuchs, Damiano Azzinnari, Christopher R Pryce, Salome Kurth, Reto Huber
Disturbed sleep and altered sleep homeostasis are core features of many psychiatric disorders such as depression. Chronic uncontrollable stress is considered an important factor in the development of depression, but little is known on how chronic stress affects sleep regulation and sleep homeostasis. We therefore examined the effects of chronic social stress (CSS) on sleep regulation in mice. Adult male C57BL/6 mice were implanted for electrocortical recordings (ECoG) and underwent either a 10-day CSS protocol or control handling (CON)...
March 15, 2017: Behavioural Brain Research
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