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https://www.readbyqxmd.com/read/29238392/risk-for-depression-burnout-and-low-quality-of-life-among-personnel-of-a-university-hospital-in-italy-is-a-consequence-of-the-impact-one-economic-crisis-in-the-welfare-system
#1
M G Carta, A Preti, I Portoghese, E Pisanu, D Moro, M Pintus, E Pintus, A Perra, S D'Oca, M Atzeni, M Campagna, E Fabrici Pascolo, F Sancassiani, G Finco, E D'Aloja, L Grassi
Background: Research literature suggests that burnout, depression, and a low mental quality of life (QOL) are common among health care workers. Economic crisis might have increased the burden of burnout, depression and low QOL in health care workers. Objectives: To identify depression risk, burnout levels, and quality of life in a sample of workers of an Italian university hospital. Method: Cross sectional study with comparison with two community surveys database results (n = 2000 and 1500, respectively)...
2017: Clinical Practice and Epidemiology in Mental Health: CP & EMH
https://www.readbyqxmd.com/read/29237783/biographical-feature-richard-b-tom-thomson-jr-ph-d-d-abmm-f-aam
#2
Erik Munson
"The previous era was characterized by house staff laboratories in every ward, and house staff and attending physicians often spent long periods performing a diagnostic examination of the expectorated sputum specimen, which had been obtained with great care and plated for prompt incubation in incubators on the ward. Therapeutic decisions were generally based on these results. During the past 30 years, there has been a notable decline in the quality of this exercise. Some of this decline can be ascribed to the Clinical Laboratory Improvement Amendments of 1988, which required that staff have credentials to interpret Gram stains of any specimens, thus essentially eliminating the house staff laboratory...
December 13, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29211696/green-neutrophilic-inclusions-current-understanding-and-review-of-literature
#3
Jay Yang, Ali Gabali
PURPOSE OF REVIEW: Green cytoplasmic inclusions in neutrophils are an uncommon finding on the peripheral blood smear. A comprehensive review of the literature is presented here with the goal of summarizing knowledge to date and increasing awareness. RECENT FINDINGS: A total of 41 cases have been reported in the literature, indicating the rarity of these green neutrophilic inclusions. Clinically, the inclusions have most consistently been associated with elevated transaminases, hepatic failure, and a high early mortality rate...
January 2018: Current Opinion in Hematology
https://www.readbyqxmd.com/read/29200524/health-care-workers-occupational-exposures-to-body-fluids-in-21-countries-in-africa-systematic-review-and-meta-analysis
#4
REVIEW
Asa Auta, Emmanuel O Adewuyi, Amom Tor-Anyiin, David Aziz, Esther Ogbole, Brian O Ogbonna, Davies Adeloye
Objective: To estimate the lifetime and 12-month prevalence of occupational exposure to body fluids among health-care workers in Africa. Methods: Embase®, PubMed® and CINAHL databases were systematically searched for studies published between January 2000 and August 2017 that reported the prevalence of occupational exposure to blood or other body fluids among health-care workers in Africa. The continent-wide prevalence of exposure was estimated using random-effects meta-analysis...
December 1, 2017: Bulletin of the World Health Organization
https://www.readbyqxmd.com/read/29199043/evaluating-interest-in-an-influenza-a-h5n1-vaccine-among-laboratory-workers-who-work-with-highly-pathogenic-avian-influenza-viruses-in-the-united-states
#5
Kate E Russell, J S Bresee, J M Katz, S J Olsen
BACKGROUND: Highly pathogenic avian influenza A (HPAI) viruses found in poultry and wild birds occasionally infect humans and can cause serious disease. In 2014, the Advisory Committee on Immunization Practices (ACIP) reviewed data from one licensed ASO3-adjuvanted influenza A(H5N1) vaccine for consideration of use during inter-pandemic periods among persons with occupational exposure. To guide vaccine policy decisions, we conducted a survey of laboratory workers to assess demand for HPAI vaccination...
November 30, 2017: Vaccine
https://www.readbyqxmd.com/read/29192599/medical-laboratory-technician-professional-pathologies-a-2006-2016-literature-review
#6
Richard Pougnet, Brice Loddé, Marie Uguen, Bénédicte Sawicki, Laurence Pougnet
The trade of laboratory technician (TL) exposes to many risks to health, because of biological or chemical or physical exposures. But the TL occupation is constantly evolving, the techniques are constantly changing. The purpose of this article is to take stock of the occupational TL pathologies which were recently described in the literature. This is a literature review, based on Medline® and Scopus® medical databases, on publications between 01/01/2006 and 31/12/2016. The research was conducted in French and English...
December 1, 2017: Annales de Biologie Clinique
https://www.readbyqxmd.com/read/29190713/operational-evaluation-of-rapid-diagnostic-testing-for-ebola-virus-disease-in-guinean-laboratories
#7
Amanda VanSteelandt, Josephine Aho, Kristyn Franklin, Jacques Likofata, Jean Baptiste Kamgang, Sakoba Keita, Lamine Koivogui, N'Faly Magassouba, Lise D Martel, Anicet George Dahourou
BACKGROUND: Rapid Diagnostic Tests (RDTs) for Ebola Virus Disease (EVD) at the point of care have the potential to increase access and acceptability of EVD testing and the speed of patient isolation and secure burials for suspect cases. A pilot program for EVD RDTs in high risk areas of Guinea was introduced in October 2015. This paper presents concordance data between EVD RDTs and PCR testing in the field as well as an assessment of the acceptability, feasibility, and quality assurance of the RDT program...
2017: PloS One
https://www.readbyqxmd.com/read/29171252/multichannel-dynamic-interfacial-printing-an-alternative-multicomponent-droplet-generation-technique-for-lab-in-a-drop
#8
Shenglong Liao, Xinglei Tao, Yingjiao Ju, Jie Feng, Wenbin Du, Yapei Wang
Generation of uniform emulsion droplets mixed with multiple components is one of the key issues in the field of lab in a drop. Traditionally, droplet microfluidic chips are often served as the prime choice while designing and fabricating microfluidic chips always rely on skilled technician and specialized equipment, severely restricting its wide accessibility. In this work, an alternative technique, called multichannel dynamic interfacial printing (MC-DIP), was proposed for multicomponent droplet generation...
December 6, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29158151/a-novel-liquid-media-mycobacteria-extraction-method-for-maldi-tof-ms-identification-using-vitek%C3%A2-ms
#9
Erik Moreno, Eric Miller, Elizabeth Miller, Heather Totty, Parampal Deol
A low-cost identification method that can be performed directly from a positive liquid medium culture is needed for the diagnosis of mycobacterial infections. Here, we describe a novel, cost-effective, and validated method that allows for direct and rapid identification of mycobacteria from a positive liquid culture using VITEK® MS with a total process duration under 45min. From a liquid mycobacteria culture a 3.0mL aliquot is removed 24-72h post positivity and centrifuged to create a pellet. After decanting, the tube is blotted dry, the pellet is re-suspended in 0...
November 17, 2017: Journal of Microbiological Methods
https://www.readbyqxmd.com/read/29149314/how-the-introduction-of-a-human-resources-information-system-helped-the-democratic-republic-of-congo-to-mobilise-domestic-resources-for-an-improved-health-workforce
#10
Jean-Robert Likofata Esanga, Claire Viadro, Leah McManus, Jennifer Wesson, Nicaise Matoko, Epiphane Ngumbu, Kate E Gilroy, Daren Trudeau
The Democratic Republic of Congo has flagged health workforce management and compensation as issues requiring attention, including the problem of ghost workers (individuals on payroll who do not exist and/or show up at work). Recognising the need for reliable health workforce information, the government has worked to implement iHRIS, an open source human resources information system that facilitates health workforce management. In Kasaï Central and Kasaï Provinces, health workers brought relevant documentation to data collection points, where trained teams interviewed them and entered contact information, identification, photo, current job, and employment and education history into iHRIS on laptops...
November 1, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/29143620/optimising-diagnosis-of-viraemic-hepatitis-c-infection-the-development-of-a-target-product-profile
#11
Elena Ivanova Reipold, Philippa Easterbrook, Alessandra Trianni, Nivedha Panneer, Douglas Krakower, Stefano Ongarello, Teri Roberts, Veronica Miller, Claudia Denkinger
BACKGROUND: The current low access to virological testing to confirm chronic viraemic HCV infection in low- and middle-income countries (LMIC) is limiting the rollout of hepatitis C (HCV) care. Existing tests are complex, costly and require sophisticated laboratory infrastructure. Diagnostic manufacturers need guidance on the optimal characteristics a virological test needs to have to ensure the greatest impact on HCV diagnosis and treatment in LMIC. Our objective was to develop a target product profile (TPP) for diagnosis of HCV viraemia using a global stakeholder consensus-based approach...
November 1, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29140384/two-bilateral-zygomatic-implants-placed-and-immediately-loaded-a-retrospective-chart-review-with-up-to-54-month-follow-up
#12
Jay Neugarten, Frank J Tuminelli, Leora Walter
PURPOSE: To report on the outcome of placement of two bilateral zygomatic implants with an immediately loaded prosthesis. MATERIALS AND METHODS: A retrospective chart review was conducted of all patients treated with zygomatic implants between August 1, 2011 and June 6, 2016. All patients had at least two zygomatic implants placed bilaterally and immediately loaded with a provisional prosthesis the same day of implant placement. The implants were Nobel Biocare TiUnite or machined surface with lengths of 30 to 52...
November 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29131539/molecular-testing-on-endobronchial-ultrasound-ebus-fine-needle-aspirates-fna-impact-of-triage
#13
Simon Sung, John P Crapanzano, David DiBardino, David Swinarski, William A Bulman, Anjali Saqi
BACKGROUND: Endobronchial ultrasound (EBUS)-guided fine needle aspiration (FNA) is performed to diagnose and stage lung cancer. Multiple studies have described the value of Rapid On-Site Evaluation (ROSE), but often the emphasis is upon diagnosis than adequacy for molecular testing (MT). The aim was to identify variable(s), especially cytology-related, that can improve MT. METHODS: A search for EBUS-FNAs with ROSE was conducted for lung adenocarcinomas or when this diagnosis could not be excluded...
November 12, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29121871/predictive-abilities-of-cardiovascular-biomarkers-to-rapid-decline-of-renal-function-in-chinese-community-dwelling-population-a-5-year-prospective-analysis
#14
Shihui Fu, Chunling Liu, Leiming Luo, Ping Ye
BACKGROUND: Predictive abilities of cardiovascular biomarkers to renal function decline are more significant in Chinese community-dwelling population without glomerular filtration rate (GFR) below 60 ml/min/1.73m(2), and long-term prospective study is an optimal choice to explore this problem. Aim of this analysis was to observe this problem during the follow-up of 5 years. METHODS: In a large medical check-up program in Beijing, there were 948 participants with renal function evaluated at baseline and follow-up of 5 years...
November 9, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/29114435/hepatitis-c-virus-genie-a-web-2-0-interpretation-and-analytics-platform-for-the-versant-hepatitis-c-virus-genotype-line-probe-assay-version-2-0
#15
Alex M Dussaq, Abha Soni, Christopher Willey, Seung L Park, Shuko Harada
Context: Hepatitis C virus (HCV) genotyping at our institution is performed using the Versant HCV genotype 2.0 Line Probe Assay (LiPA). The last steps of this procedure are manual, laborious, and error-prone process that involves the comparison of the banding pattern on a test strip to a physical reference table. Aim: We developed a web-based HCV genotype interpretation platform that utilizes a scanned image to generate the genotypes, thus minimizing interpretation time and reducing error...
2017: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/29091945/laboratory-evaluation-of-immunochromatographic-rapid-diagnostic-tests-for-cholera-in-haiti
#16
Wilfredo R Matias, Fabrice E Julceus, Cademil Abelard, Leslie M Mayo-Smith, Molly F Franke, Jason B Harris, Louise C Ivers
BACKGROUND: Rapid diagnostic tests (RDT) for cholera are promising tools for detecting cholera in areas with limited laboratory infrastructure. However, evidence on the characteristics of the many available RDTs is scarce, and their use has been limited by suboptimal performance. We evaluated the performance characteristics of three cholera RDTs from Span Diagnostics, Artron Laboratories, and Standard Diagnostics in a regional laboratory in Haiti. METHODOLOGY/PRINCIPAL FINDINGS: We retrospectively reviewed records from May 2014 to October 2015 of a laboratory-based surveillance program for Vibrio cholerae at Hôpital Saint-Nicolas in Saint-Marc, Haiti...
2017: PloS One
https://www.readbyqxmd.com/read/29089863/relationships-of-drinking-and-smoking-with-peripheral-arterial-stiffness-in-chinese-community-dwelling-population-without-symptomatic-peripheral-arterial-disease
#17
Shihui Fu, Qixian Wu, Leiming Luo, Ping Ye
BACKGROUND: Peripheral arterial stiffness gives rise to the high prevalence of peripheral arterial disease (PAD). It is necessary to conduct a large-scale study in Chinese community-dwelling population to clarify the relationships of alcohol and tobacco consumption with peripheral arterial stiffness. Most studies had a small sample size, and were not performed in Chinese community-dwelling population without symptomatic PAD. This analysis was designed to examine the relationships of alcohol and tobacco consumption with peripheral arterial stiffness in Chinese community-dwelling population without symptomatic PAD...
2017: Tobacco Induced Diseases
https://www.readbyqxmd.com/read/29083134/clinical-endocrinology-and-hormones-quantitation-the-increasing-role-of-mass-spectrometry
#18
Federica D'Aurizio, Marco Cantù
Clinical endocrinology has always had a close relationship with laboratory medicine. In fact, the quantification of hormones is of great importance for diagnosis, treatment, recurrence and patient's prognosis of endocrine disorders. This review dealt with the role of the laboratory in diagnosing endocrine pathologies related to adrenal gland, pituitary, gonads and thyroid. The measurements of the main hormones (17- hydroxyprogesterone, androstenedione, dehydroepiandrosterone sulphate, testosterone, estradiol, cortisol, aldosterone, metanephrines, thyroglobulin and insulin-like-growth factor-1) were described considering analytical characteristics but also some aspects of pre-analytical and post- analytical steps...
October 27, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/29081654/association-between-serum-%C3%AE-2-microglobulin-levels-and-frailty-in-an-elderly-chinese-population-results-from-rulas
#19
Zu-Yun Liu, Yan-Yu Shen, Li-Juan Ji, Xiao-Yan Jiang, Xiao-Feng Wang, Yan Shi
OBJECTIVE: To examine the association between serum β2-microglobulin (B2M) levels and frailty in an elderly Chinese population. DESIGN: A population-based cohort study. SETTING AND PARTICIPANTS: We used data on 1,663 elderly participants (aged 70-84 years) from the aging arm of the Rugao Longevity and Ageing study, a population-based observational two-arm cohort study conducted in Rugao, China. MEASUREMENTS: The serum B2M was measured with chemiluminescence immunoassay by a technician in the biochemistry laboratory of the Rugao People's Hospital...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29078791/lessons-from-the-field-the-conduct-of-randomized-controlled-trials-in-botswana
#20
Janice M Bonsu, Rosemary Frasso, Allison E Curry
BACKGROUND: The conduct of randomized controlled trials (RCTs) in low-resource settings may present unique financial, logistic, and process-related challenges. Middle-income countries that have comparable disease burdens to low-income countries, but greater availability of resources, may be conducive settings for RCTs. Indeed, the country of Botswana is experiencing a rapid increase in the conduct of RCTs. Our objective was to explore the experiences of individuals conducting RCTs in Botswana to gain an understanding of the challenges and adaptive strategies to their work...
October 27, 2017: Trials
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