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https://www.readbyqxmd.com/read/28894422/does-heel-height-cause-imbalance-during-sit-to-stand-task-surface-emg-perspective
#1
Ganesh R Naik, Ahmed Al-Ani, Massimiliano Gobbo, Hung T Nguyen
The purpose of this study was to determine whether electromyography (EMG) muscle activities around the knee differ during sit-to-stand (STS) and returning task for females wearing shoes with different heel heights. Sixteen healthy young women (age = 25.2 ± 3.9 years, body mass index = 20.8 ± 2.7 kg/m(2)) participated in this study. Electromyography signals were recorded from the two muscles, vastus medialis (VM) and vastus lateralis (VL) that involve in the extension of knee. The participants wore shoes with five different heights, including 4, 6, 8, 10, and 12 cm...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28889091/mri-in-sarcoglycanopathies-a-large-international-cohort-study
#2
Giorgio Tasca, Mauro Monforte, Jordi Díaz-Manera, Giacomo Brisca, Claudio Semplicini, Adele D'Amico, Fabiana Fattori, Anna Pichiecchio, Angela Berardinelli, Lorenzo Maggi, Elio Maccagnano, Nicoline Løkken, Chiara Marini-Bettolo, Francina Munell, Angel Sanchez, Nahla Alshaikh, Nicol C Voermans, Jahannaz Dastgir, Dmitry Vlodavets, Jana Haberlová, Gianmichele Magnano, Maggie C Walter, Susana Quijano-Roy, Robert-Yves Carlier, Baziel G M van Engelen, John Vissing, Volker Straub, Carsten G Bönnemann, Eugenio Mercuri, Francesco Muntoni, Elena Pegoraro, Enrico Bertini, Bjarne Udd, Enzo Ricci, Claudio Bruno
OBJECTIVES: To characterise the pattern and spectrum of involvement on muscle MRI in a large cohort of patients with sarcoglycanopathies, which are limb-girdle muscular dystrophies (LGMD2C-2F) caused by mutations in one of the four genes coding for muscle sarcoglycans. METHODS: Lower limb MRI scans of patients with LGMD2C-2F, ranging from severe childhood variants to milder adult-onset forms, were collected in 17 neuromuscular referral centres in Europe and USA...
September 9, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28857115/muscle-function-and-coordination-of-stair-ascent
#3
Nicole Harper, Jason Wilken, Richard Neptune
Stair ascent is an activity of daily living and necessary for maintaining independence in community environments. One challenge to improving an individual's ability to ascend stairs is a limited understanding of how lower-limb muscles work in synergy to perform stair ascent. Through dynamic coupling muscles may perform multiple functions and require contributions from other muscles to perform a task successfully. The purpose of this study was to identify the functional roles of individual muscles during stair ascent and the mechanisms by which muscles work together to perform specific subtasks...
August 31, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28763714/muscle-contributions-to-knee-extension-in-the-early-stance-phase-in-patients-with-knee-osteoarthritis
#4
Shinya Ogaya, Ryo Kubota, Yuta Chujo, Eiko Hirooka, Kim Kwang-Ho, Kimitaka Hase
The aim of this study was to analyze individual muscle contributions to knee angular acceleration using a musculoskeletal simulation analysis and evaluate knee extension mechanics in the early stance phase in patients with knee osteoarthritis (OA). The subjects comprised 15 patients with medial knee OA and 14 healthy elderly individuals. All participants underwent gait performance test using 8 infrared cameras and two force plates to measure the kinetic and kinematic data. The simulation was driven by 92 Hill-type muscle-tendon units of the lower extremities and a trunk with 23° of freedom...
July 23, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28761699/high-intensity-flywheel-exercise-and-recovery-of-atrophy-after-90-days-bed-rest
#5
Daniel L Belavý, Hiroshi Ohshima, Jörn Rittweger, Dieter Felsenberg
AIMS: To investigate differential muscle atrophy during bed-rest, the impact of a high-intensity concentric-eccentric (flywheel) resistance exercise countermeasure and muscle recovery after bed-rest. METHODS: Twenty-five healthy male subjects underwent 90 dayshead-down tilt bed-rest. Volume of individual lower-limb muscles was measured via MRI before, twice during and four times up to 1 year after bed-rest. Subjects were either inactive (n=16) or performed flywheel exercise every third day of bed-rest (n=9)...
2017: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/28750972/lower-limb-muscular-activity-during-walking-at-different-speeds-over-ground-versus-treadmill-walking-a-voluntary-response-evaluation
#6
Khosro Khademi-Kalantari, Fatemeh Rahimi, Seyed Majid Hosseini, Alireza Akbarzade Baghban, Shapour Jaberzadeh
OBJECTIVE: To evaluate the overall lower limb muscular activity pattern during treadmill walking compared to over-ground walking. METHODOLOGY: The study was conducted on 25 healthy young females. Surface electromyography was recorded from gastrocnemius, hamstrings, vasti and gluteus medius muscles during walking over-ground and treadmill at 3 different speeds (comfortable, slow and fast). The pattern of muscle activity was compared between two walking conditions at different speeds by the voluntary response index method...
July 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/28725437/towards-evidence-based-strength-training-a-comparison-of-muscle-forces-during-deadlifts-goodmornings-and-split-squats
#7
Florian Schellenberg, William R Taylor, Silvio Lorenzetti
BACKGROUND: To ensure an efficient and targeted adaptation with low injury risk during strength exercises, knowledge of the participant specific internal loading conditions is essential. The goal of this study was to calculate the lower limb muscles forces during the strength exercises deadlifts, goodmornings and splits squats by means of musculoskeletal simulation. METHODS: 11 participants were assessed performing 10 different variations of split squats by varying the step length as well as the maximal frontal tibia angle, and 13 participants were measured performing deadlift and goodmorning exercises...
2017: BMC Sports Science, Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28710478/recombinant-fasciola-hepatica-fatty-acid-binding-protein-suppresses-toll-like-receptor-stimulation-in-response-to-multiple-bacterial-ligands
#8
Marcos J Ramos-Benítez, Caleb Ruiz-Jiménez, Vasti Aguayo, Ana M Espino
Recently, we reported that a native Fasciola hepatica fatty acid binding protein (FABP) termed Fh12 is a powerful anti-inflammatory protein capable of suppressing the LPS-induced expression of inflammatory markers in vivo and in vitro. Because the purification of a protein in native form is, in many situations not cost-beneficial and unsuitable for industrial grade scale-up, this study accomplished the task of optimizing the expression and purification of a recombinant form of FABP (Fh15). Additionally, we ascertained whether this molecule could exhibit a similar suppressive effect on TLR-stimulation and inflammatory cytokine expression from macrophages than those previously demonstrated for the native molecule...
July 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28702442/kinematics-and-neuromuscular-recruitment-during-vertical-treadmill-exercise
#9
Alastair R Jordan, Andrew Barnes, David Claxton, Alison Purvis, Mary Fysh
The vertical treadmill (VertiRun) is an unresearched, partial weight-bearing exercise mode for lower limb rehabilitation. The user undertakes a "running-like" action whilst body weight is supported by a bench and the limb is drawn downwards against overhanging resistance cables on a vertically hung nonmotorised treadmill. This study sought to describe the kinematics and neuromuscular recruitment during VertiRun exercise in the supine, 40°, and 70° postures. Twenty-one healthy male participants (age, 25±7 years; stature, 1...
June 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/28349768/effect-of-body-weight-support-variation-on-muscle-activities-during-robot-assisted-gait-a-dynamic-simulation-study
#10
Shahid Hussain, Prashant K Jamwal, Mergen H Ghayesh
BACKGROUND AND OBJECTIVES: While body weight support (BWS) intonation is vital during conventional gait training of neurologically challenged subjects, it is important to evaluate its effect during robot assisted gait training. In the present research we have studied the effect of BWS intonation on muscle activities during robotic gait training using dynamic simulations. METHODS: Two dimensional (2-D) musculoskeletal model of human gait was developed conjointly with another 2-D model of a robotic orthosis capable of actuating hip, knee and ankle joints simultaneously...
May 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28063859/assessing-palliative-care-content-in-dementia-care-guidelines-a-systematic-review
#11
REVIEW
Pamela Durepos, Abigail Wickson-Griffiths, Afeez Abiola Hazzan, Sharon Kaasalainen, Vasilia Vastis, Lisa Battistella, Alexandra Papaioannou
CONTEXT: Families of persons with dementia continue to report unmet needs during end of life (EOL). Strategies to improve care and quality of life for persons with dementia include development of clinical practice guidelines (CPGs) and an integrative palliative approach. OBJECTIVES: We aimed to assess palliative care content in dementia CPGs to identify the presence or limitations of recommendations and discussion pertaining to common issues or domains affected by illness as described by the Canadian Hospice Palliative Care Association "Square of Care...
April 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28027463/quantifying-knee-mechanics-during-balance-training-exercises
#12
Lauren C Benson, Thomas G Almonroeder, Kristian M O'Connor
Patellofemoral pain (PFP) is common among runners and those recovering from anterior cruciate ligament reconstruction. Training programs designed to prevent or treat injuries often include balance training, although balance interventions have been reported to coincide with more knee injuries. Knowledge of the effect of balance exercises on knee mechanics may be useful when designing training programs. High knee abduction moment has been implicated in the development of PFP, and imbalance between vastus lateralis (VL) and vastus medialis oblique (VMO) may contribute to patellofemoral stress...
January 2017: Human Movement Science
https://www.readbyqxmd.com/read/27924948/foxa1-gata3-and-ppar%C3%A9-cooperate-to-drive-luminal-subtype-in-bladder-cancer-a-molecular-analysis-of-established-human-cell-lines
#13
Joshua I Warrick, Vonn Walter, Hironobu Yamashita, Eunah Chung, Lauren Shuman, Vasty Osei Amponsa, Zongyu Zheng, Wilson Chan, Tiffany L Whitcomb, Feng Yue, Tejaswi Iyyanki, Yuka I Kawasawa, Matthew Kaag, Wansong Guo, Jay D Raman, Joo-Seop Park, David J DeGraff
Discrete bladder cancer molecular subtypes exhibit differential clinical aggressiveness and therapeutic response, which may have significant implications for identifying novel treatments for this common malignancy. However, research is hindered by the lack of suitable models to study each subtype. To address this limitation, we classified bladder cancer cell lines into molecular subtypes using publically available data in the Cancer Cell Line Encyclopedia (CCLE), guided by genomic characterization of bladder cancer by The Cancer Genome Atlas (TCGA)...
December 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27918690/the-advantages-of-normalizing-electromyography-to-ballistic-rather-than-isometric%C3%A2-or-isokinetic-tasks
#14
Stephen M Suydam, Kurt Manal, Thomas S Buchanan
Isometric tasks have been a standard for electromyography (EMG) normalization stemming from anatomic and physiologic stability observed during contraction. Ballistic dynamic tasks have the benefit of eliciting maximum EMG signals for normalization, despite having the potential for greater signal variability. It is the purpose of this study to compare maximum voluntary isometric contraction (MVIC) to nonisometric tasks with increasing degrees of extrinsic variability, ie, joint range of motion, velocity, rate of contraction, etc...
June 26, 2017: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/27898096/on-a-fox-hunt-functions-of-fox-transcriptional-regulators-in-bladder-cancer
#15
REVIEW
Hironobu Yamashita, Vasty Osei Amponsa, Joshua I Warrick, Zongyu Zheng, Peter E Clark, Jay D Raman, Xue-Ru Wu, Cathy Mendelsohn, David J DeGraff
Genomic and transcriptional studies have identified discrete molecular subtypes of bladder cancer. These observations could be the starting point to identify new treatments. Several members of the forkhead box (FOX) superfamily of transcription factors have been found to be differentially expressed in the different bladder cancer subtypes. In addition, the FOXA protein family are key regulators of embryonic bladder development and patterning. Both experimental and clinical data support a role for FOXA1 and FOXA2 in urothelial carcinoma...
February 2017: Nature Reviews. Urology
https://www.readbyqxmd.com/read/27893474/hypertrophy-and-explosive-reactive-functioning-in-sedentary-men-following-10-weeks-of-whole-body-vibration
#16
Jens Ebing, Ulf Gast, Christoph Hauptmann, Dieter Felsenberg, Daniel L Belavý
The objective of this study was to determine the impact of vertical (Power-plate; POW) and side-alternating (Galileo; GAL) whole-body vibration exercise on muscle mass and lower-limb neuromuscular function. Forty-three sedentary male subjects (18-30yr) randomized into three groups underwent two upper-body exercise sessions per week for 10 weeks. Two groups of subjects underwent additional squat exercises on the GAL (N=15) or POW (N=14) devices. The third group was control. On magnetic resonance imaging, volume of the thigh muscles was measured...
November 16, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27814851/does-leg-predomination-affect-the-measurement-of-vasti-muscle-activity-during-single-leg-squatting-a-reliability-study
#17
Javid Mostamand, Dan L Bader, Zoë Hudson
INTRODUCTION: Although measuring vasti muscle activity may reveal whether pain relief is associated with altering this parameter during functional activities in subjects with patellofemoral pain syndrome (PFPS), it may be necessary to determine whether the inherent properties of the dominant leg influences the reliability of measuring VMO/VL amplitude. The aim of the present study was to examine the effect of leg predomination on reliability testing of the VMO/VL amplitude measurement during single leg squatting in healthy subjects...
October 2016: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/27592299/prophylactic-knee-bracing-alters-lower-limb-muscle-forces-during-a-double-leg-drop-landing
#18
Katie A Ewing, Justin W Fernandez, Rezaul K Begg, Mary P Galea, Peter V S Lee
Anterior cruciate ligament (ACL) injury can be a painful, debilitating and costly consequence of participating in sporting activities. Prophylactic knee bracing aims to reduce the number and severity of ACL injury, which commonly occurs during landing maneuvers and is more prevalent in female athletes, but a consensus on the effectiveness of prophylactic knee braces has not been established. The lower-limb muscles are believed to play an important role in stabilizing the knee joint. The purpose of this study was to investigate the changes in lower-limb muscle function with prophylactic knee bracing in male and female athletes during landing...
October 3, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27553849/the-functional-roles-of-muscles-during-sloped-walking
#19
Nathaniel T Pickle, Alena M Grabowski, Arick G Auyang, Anne K Silverman
Sloped walking is biomechanically different from level-ground walking, as evidenced by changes in joint kinematics and kinetics. However, the changes in muscle functional roles underlying these altered movement patterns have not been established. In this study, we developed a total of 273 muscle-actuated simulations to assess muscle functional roles, quantified by induced body center-of-mass accelerations and trunk and leg power, during walking on slopes of 0°, ±3°, ±6°, and ±9° at 1.25m/s. The soleus and gastrocnemius both provided greater forward acceleration of the body parallel to the slope at +9° compared to level ground (+126% and +66%, respectively)...
October 3, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27522538/muscle-contributions-to-frontal-plane-angular-momentum-during-walking
#20
Richard R Neptune, Craig P McGowan
The regulation of whole-body angular momentum is important for maintaining dynamic balance during human walking, which is particularly challenging in the frontal plane. Whole-body angular momentum is actively regulated by individual muscle forces. Thus, understanding which muscles contribute to frontal plane angular momentum will further our understanding of mediolateral balance control and has the potential to help diagnose and treat balance disorders. The purpose of this study was to identify how individual muscles and gravity contribute to whole-body angular momentum in the frontal plane using a muscle-actuated forward dynamics simulation analysis...
September 6, 2016: Journal of Biomechanics
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