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Jyoti R Misra, Kenneth D Irvine
The protocadherins Dachsous and Fat initiate a signaling pathway that controls growth and planar cell polarity by regulating the membrane localization of the atypical myosin Dachs. How Dachs is regulated by Fat signaling has remained unclear. Here we identify the vamana gene as playing a crucial role in regulating membrane localization of Dachs and in linking Fat and Dachsous to Dachs regulation. Vamana, an SH3-domain-containing protein, physically associates with and co-localizes with Dachs and promotes its membrane localization...
October 7, 2016: Developmental Cell
Nirupam Bhattacharyya, Muralidhar P Pujar, Ashutosh Chaturvedi, M Ashvini Kumar, B A Lohith, K N Sunil Kumar
OBJECTIVES: Wrightia antidysenterica Linn. (WA) is male variety Kutaja stated to be potent therapeutic emetic agent in skin disorders. Expulsion of doshas through oral route is termed as Vamana Karma (VK) (therapeutic emesis). However, so far, its utility for Vamana is not explored in detail, therefore there is a need to revalidate the utility of WA for Vamana. Hence, the above study was conducted to ascertain the efficacy as a therapeutic emetic agent (vamaka yoga) in the management of psoriasis along with quality control and standardization of this herb...
March 2016: Pharmacognosy Research
Eliška Záveská, Tomáš Fér, Otakar Šída, Karol Marhold, Jana Leong-Škorničková
Discerning relationships among species evolved by reticulate and/or polyploid evolution is not an easy task, although it is widely discussed. The economically important genus Curcuma (ca. 120 spp.; Zingiberaceae), broadly distributed in tropical SE Asia, is a particularly interesting example of a group of palaeopolyploid origin whose evolution is driven mainly by hybridization and polyploidization. Although a phylogeny and a new infrageneric classification of Curcuma, based on commonly used molecular markers (ITS and cpDNA), have recently been proposed, significant evolutionary questions remain unresolved...
July 2016: Molecular Phylogenetics and Evolution
Sreelakshmi Chaganti, B S Prasad
Virechana (therapeutic purgation) is a common procedure that is widely practiced among the panchakarma treatments (pentad treatments). Various Virechaka dravyas (purgative drugs) have been described for Virechana. Even after critical analysis of Virechaka dravyas in the literature, still there is difficulty in the fixation of dose. Hence, the retrospective analysis of varied outcomes of Virechana with Danti (Baliospermum montanum) avaleha (linctus) is discussed in this paper. The study included twenty-seven case reports of patients who were administered Virechana with Danti avaleha...
October 2015: Journal of Ayurveda and Integrative Medicine
Priyadarshani Arvind Kadus, Surendra M Vedpathak
Oral administration of medicated fats (oil or ghee) is termed as Snehapana. It is an essential step before Vamana (therapeutic emesis) and Virechana (therapeutic purgation). Ayurveda physicians often experience a poor compliance in 10-15% patients for oral administration of medicated fats especially in escalating doses. Incomplete Snehapana sometimes creates a problem for a physician to prepare the patient for these processes. These inconveniences made us think about effective alternatives to counter drawbacks and improve acceptance of Snehapana...
October 2014: Journal of Ayurveda and Integrative Medicine
Tukaram S Dudhamal, Madhav Singh Baghel, Chaturbhuja Bhuyan, Sanjay Kumar Gupta
BACKGROUND: Parikartika resembles fissure-in-ano which is very common among all ano-rectal disorders. In Ayurvedic texts, Parikartika is described as a complication of Vamana and Virechana as well as complication of Atisara. Ksharasutra was proved successful in the management of fistula-in-ano, piles, and there is a need to try its efficacy in fissure-in-ano. AIM: To evaluate the role of Ksharasutra suturing (KSS) in fissure bed in chronic fissure-in-ano. MATERIALS AND METHODS: Total 100 patients of chronic fissure-in-ano were selected and randomly divided into two groups (50 in each group)...
April 2014: Ayu
Iyyappan Rajan, Remitha Rabindran, P R Jayasree, P R M Kumar
Free radical scavenging activity, ferrous ion chelating capacity, reducing power and genoprotective effect of the aqueous leaf extracts of four unexplored endemic Curcuma spp. (C. vamana, C. neilgherrensis, C. mutabilis, C. haritha) were found to be dose-dependent and were highest in C. vamana. DNA protection property of the extracts was evaluated against H202/UV-induced oxidative damage. DNA-methyl green displacement assay showed that these extracts were free of DNA intercalating compounds. Further, hemolysis assay also showed that the extracts were non-toxic to human erythrocytes...
February 2014: Indian Journal of Experimental Biology
Nitin Jindal, Nayan P Joshi
Diabetes mellitus (DM) with its devastating consequences is a global health problem of this era. Presently India is having the largest diabetic population of 50.8 million. The characteristic features of DM have close resemblance with Prameha (obstinate urinary disorders including diabetes) in Ayurveda. Madhumeha is a Vatika subtype of Prameha that is most close to DM. One variety of this Madhumeha (DM) is Aavaranjanya (due to occlusion) in which Vayu aggravates due to occlusion by Pitta or Kapha. This type of Madhumeha (DM) can be managed if Samshodhana (bio-cleansing) is used in early stages of disease followed by palliative treatment...
July 2013: Ayu
Sora Yasri, Viroj Wiwanitkit
No abstract text is available yet for this article.
January 2013: Ancient Science of Life
Narra Vijayalakshmi
Sadyo Vamana is a type of purificatory measure mentioned in Ayurveda, which to expel the pus and morbid factors present in a dental abscess without opening it. However, Sadyo Vamana's role in fever and pus filled dental abscess has not been reported so far. I report a case of dental abscess with fever. A 24-year-old male patient with a pus filled dental abscess. His fever and dental abscess didn't respond to antibiotic and analgesic treatment for 10 days. The patient was given Sadyo Vamana (instant therapeutic emesis) to expel the accumulated pus in dental abscess without opening it...
October 2012: Ancient Science of Life
Ranjip Kumar Dass, Nilesh N Bhatt, Anup B Thakar, Vagish Dutt Shukla
Vamana Karma (process of emesis) is considered as Pradhana Karma (prime procedure) meant for inducing therapeutic vomiting, indicated for the purification of Urdhwa Bhaga (upper part) of the body. It is the process by which contents of stomach, including Kapha and Pitta are expelled out of the body through oral route. Acharya Charak and Sushruta have advocated various procedures for Vamana Karma known as classical methods, whereas some traditional methods are also being followed. As very little works has been carried out in the direction of Vamana Karma and as not a single work has been carried out on standardization of Vamana Vidhi comparing to both classical and traditional methods, the present study had been selected...
October 2012: Ayu
Bharti Gupta, Sushil C Mahapatra, Renu Makhija, Adarsh Kumar, Nikhil M Jirankalgikar, Madan M Padhi, Ramesh Babu Devalla
Vamana Karma (therapeutic emesis) primarily a Samshodhana Karma (purification procedure) is one of the five Pradhana Karmas (chief procedures) of Panchakarma. It is mentioned in Ayurvedic texts that a person after Samyak Vamana (proper Vamana) experiences lightness of the body, Hrit (precordium), Kantha (throat/voice), and Shirah (head) and weakness. This procedure is effectively used in healthy and ailing persons for purification of body and extraction of Doshas (especially Kapha) in Ayurvedic system. It has been found worth to observe the physiological and biochemical changes during Vamana and after the procedure to understand the effect/safety margins of the procedure in healthy volunteers...
July 2012: Ayu
Gunjan Mangal, Gopesh Mangal, Radhey Shyam Sharma
In India an estimated 0.8% of the population is suffering from Psoriasis. It is a papulo-squamous disorder of the skin, characterized by sharply defined erythemato-squamous lesions. It is chronic and is well known for its course of remissions and exacerbations. The exact etiology is still unknown. This condition is comparable with Mandala Kushtha in Ayurvedic system of medicine. Shodhana procedures are reliable to control the disease. Forty patients, fulfilling the inclusion criteria, were selected and randomly divided into four groups with 10 patients in each group...
April 2012: Ayu
I Rajan, R Remitha, P R Jayasree, P R Manish Kumar
Leaf extracts of C. vamana, endemic to Kerala state in India, were found to inhibit cell cycle progression in synchronous cultures of P. polycephalum in a concentration and phase-specific manner. Crude alkaloid extract (CAE) elicited maximum cell cycle delays in comparison to soxhletted chloroform, acetone and aqueous extracts. Total alkaloid content of CAE was found to be 64.9 mg/g. CAE showed lowest DPPH radical scavenging activity. Other extracts with higher free radical scavenging activity exhibited lesser cell cycle inhibiting potential...
January 2013: Indian Journal of Experimental Biology
Rajeev Kumar Pandey, N N Bhatt, T M Singhala, V D Shukla
In the present study, Vamana and Virechana along with palliative treatment was given to patients of Sthula Prameha (Diabetes mellitus or DM). An attempt was made to compare and evaluate the role of Shodhana therapy (Vamana and Virechana). Total 47 patients of Sthula Pramehi were registered in this study, out of which 38 completed the treatment. The patients were divided into two groups, viz. Vamana with Shamana (Group A) and Virechana with Shamana (Group B). Eighteen patients completed the treatment in Group A and 20 in Group B...
October 2011: Ayu
Rajkala Ramteke, G Vinodkumar, T Meharjan
An open clinical trial was conducted in Govt. Ayurveda College Hospital, Thiruvananthapuram, Department of Kayachikitsa and Panchakarma. As there is no work done on the Samyak Snigdha Lakshana (SSL), this study was undertaken to work on the different aspects of Samyak Snigdha Lakshana. To minimize variables, subjects suffering with psoriasis and same Ghritam were selected on the basis of strict inclusion and exclusion criteria. Shodhananga Abhyantara Snehapana was advised before Vamana and Virechana. Samyak Snigdha Lakshanas which are described in all texts are different in milieu...
October 2011: Ayu
Jaimin R Patel, Santoshkumar Bhatted
Vamana Karma (therapeutic emesis) is the best therapy for the elimination of vitiated Kapha Dosha. In the present clinical practice Madanaphala (Randia dumetorum) is mainly used for Vamana Karma. Apart from Madanaphala, five other drugs, and in total 355 formulations are described in Charaka Samhita; one of them is Krutavedhana (Luffa acutangula) kalpa (formulations). Krutavedhana is specially indicated in Gadha (compact) Dosha condition like Kushtha (skin diseases), Garavisha (slow poison), and so on, for Vamana Karma...
October 2011: Ayu
Bharti, K Mohan, S K Tewari
A total of 36 patients of Amlapitta were selected for the clinical study. Vasa was given to 20 of them having hyperacidity and hyperchlorhydria. The patients were mainly of Urdhvaga Amlapitta. A symptomatic improvement was observed in the patients. Udgara and Vamana were considered as the presenting features of Amlapitta. A 60 ml syrup of dry leaves of Vasa (30 gm crude drug) was given to each patient in 4 divided doses for a duration of 6 weeks. Effect was assessed in terms of clinical symptomatology, free acid and total acid, in gastric juice...
January 1995: Ancient Science of Life
Somsri Wiwanitkit, Viroj Wiwanitkit
No abstract text is available yet for this article.
July 2011: Ayu
Santoshkumar Bhatted, V D Shukla, Anup Thakar, N N Bhatt
Panchakarma is the most essential part of Ayurveda treatments. It is preventive, preservative, promotive, curative and rehabilitative therapy. Ayurveda believes in strong relationship between macrocosm and microcosm and states that the seasonal changes will influence the biological systems resulting into the accumulation and aggravation of particular Dosha in a particular season like accumulation and aggravation of Kapha in Hemant Rutu (winter season) and Vasant Rutu (spring season) respectively, accumulation and aggravation of Pitta in Varsha Rutu (rainy season) and Sharad Rutu (autumn season) respectively...
April 2011: Ayu
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