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Nasya B Tomlekova, Philip J White, Jacqueline A Thompson, Emil A Penchev, Stephan Nielen
Vitamin and mineral deficiencies are prevalent in human populations throughout the world. Vitamin A deficiency affects hundreds of millions of pre-school age children in low income countries. Fruits of pepper (Capsicum annuum L.) can be a major dietary source of precursors to Vitamin A biosynthesis, such as β-carotene. Recently, pepper breeding programs have introduced the orange-fruited (of) trait of the mutant variety Oranzheva kapiya, which is associated with high fruit β-carotene concentrations, to the mutant variety Albena...
2017: PloS One
Nasya M Sturdivant, Sean G Smith, Syed F Ali, Jeffrey C Wolchok, Kartik Balachandran
Non-penetrating or mild traumatic brain injury (mTBI) is commonly experienced in accidents, the battlefield and in full-contact sports. Astrocyte cellular edema is one of the major factors that leads to high morbidity post-mTBI. Various studies have reported an upregulation of aquaporin-4 (AQP4), a water channel protein, following brain injury. AZA is an antiepileptic drug that has been shown to inhibit AQP4 expression and in this study we investigate the drug as a therapeutic to mitigate the extent of mTBI induced cellular edema...
September 14, 2016: Scientific Reports
Rajkala S Ramteke, Panchakshari D Patil, Anup B Thakar
For emergency conditions, Ayurveda has never been given importance in recent times. However, there are certain emergency conditions where biomedicine has limitations but, Ayurveda can provide solution. Classics have many references regarding management of acute conditions like syncope, coma, episodic conditions of bronchial asthma, epilepsy, etc., In the present study, a 61 year female patient had a two year history of hypertension and was suffering with coma. She was treated with an Ayurvedic treatment modality...
April 2016: Ancient Science of Life
Ishita Tandon, Atefeh Razavi, Prashanth Ravishankar, Addison Walker, Nasya M Sturdivant, Ngoc Thien Lam, Jeffrey C Wolchok, Kartik Balachandran
Valve interstitial cells are dispersed throughout the heart valve and play an important role in maintaining its integrity, function, and phenotype. While prior studies have detailed the role of external mechanical and biological factors in the function of the interstitial cell, the role of cell shape in regulating contractile function, in the context of normal and diseased phenotypes, is not well understood. Thus, the aim of this study was to elucidate the link between cell shape, phenotype, and acute functional contractile output...
October 3, 2016: Journal of Biomechanics
Karen J Coleman, Tani Hemmila, Mark D Valenti, Nasya Smith, Rachel Quarrell, Lynnice K Ruona, Emily Brandenfels, Barbara Hann, Todd Hinnenkamp, Margarita D Parra, Jeyn Monkman, Sue Vos, Rebecca C Rossom
OBJECTIVE: To understand how care managers implemented COMPASS and if this was related to patient health outcomes. METHODS: A total of 96 COMPASS care managers were approached to participate in the online survey and 93 (97%) provided responses. Correlations were generated between key survey responses and the average number of care management contacts, patient depression, blood pressure and glycosylated hemoglobin outcomes. RESULTS: Patients of care managers who reported spending more time on COMPASS-related tasks had higher rates of depression improvement (r=0...
January 2017: General Hospital Psychiatry
Manuel Joseph Vivera, Judith Streak Gomersall
BACKGROUND: Ardita (facial paralysis) is a medical condition that disfigures or distorts the facial appearance of the sufferer causing facial asymmetry and malfunction. Ardita patients may benefit from considering alternative treatments such as Ayurveda, including Taila Nasya (nasal instillation of medicated oil). OBJECTIVES: To synthesize the best available evidence on the effectiveness of different Nasya oils in the treatment of Ardita. INCLUSION CRITERIA TYPES OF PARTICIPANTS: Studies conducted on adult sufferers (18-70 years) of Ardita (chronic or acute) in any setting were considered...
April 2016: JBI Database of Systematic Reviews and Implementation Reports
Sarvesh Kumar Singh, Kshipra Rajoria
Ankylosing spondylitis (AS) is a rheumatic disease with various skeletal and extra skeletal manifestations. No satisfactory treatment is available in modern medicine for this disorder. Various Panchakarma procedures and Ayurvedic drugs have been proved useful for these manifestations. We present a case of AS, which was treated for two months with a combination of Panchakarma procedures and Ayurvedic drugs. Ayurvedic treatments, in this case, were directed toward alleviating symptoms and to reduce severe disability...
March 2016: Journal of Ayurveda and Integrative Medicine
Manjusha Rajagopala, G Gopinathan
The term Shotha ordinarily means a swelling which may be because of inflammatory process in any part of the body or may be general, due to causes other than inflammatory. A diagnosed case of papilledema (Kapha-Pittaja Drishti Nadi Shotha) was treated on the lines of Shotha Chikitsa. The patient was given Dashamoola and Punarnavashtaka Kwatha internally and locally Nasya and Takradhara for 3 months. At the end of 3 months, papilledema completely regressed. Follow-up of the patient for more than 3 years, no recurrence has been reported...
April 2015: Ayu
B S Prasad, Deepa Patil, L G Pardeep, Veerayya Hiremath, C R Shreelakshmi
INTRODUCTION: Nasya karma is prime treatment modality for ūrdhvajatrugata vikāra. Though classics clearly mention yogya (arha), ayogya (anarha) criteria for Nasya karma some complications were noticed while practicing. In KLEUS Shri BMK Ayurveda Hospital Belgaum, out of 2867 patients 58 (0.58%) cases reported various complications during and after Nasya karma in the year of 2011 even after taking utmost care in selection of patients as well as drugs. This gave rise to need to develop quick screening criteria to minimize errors...
October 2014: Ancient Science of Life
David J Rademacher, Nasya Mendoza-Elias, Gloria E Meredith
Context-drug learning produces structural and functional synaptic changes in the circuitry of the basolateral nucleus of the amygdala (BLA). However, how the synaptic changes translated to the neuronal targets was not established. Thus, in the present study, immunohistochemistry with a cell-specific marker and the stereological quantification of synapses was used to determine if context-drug learning increases the number of excitatory and inhibitory/modulatory synapses contacting the gamma-aminobutyric acid (GABA) interneurons and/or the pyramidal neurons in the BLA circuitry...
January 2015: European Journal of Neuroscience
Katharina Stoelzel, Gordana Bothe, Pee Win Chong, Minoo Lenarz
BACKGROUND: Nasya/Prevalin is a natural, drug-free nasal spray for treatment and prevention of allergic rhinitis. Because of its thixotropic property, it forms a barrier on the nasal mucosa, preventing allergen contact. This study assesses the clinical efficacy and safety of Nasya/Prevalin in a nasal provocation test with house dust mite allergens. METHODOLOGY/PRINCIPAL: In this randomised, double-blind, placebo-controlled trial, 20 subjects suffering from allergic rhinitis because of house dust mite allergens received a single dose of Nasya/Prevalin or saline spray before allergen challenge...
October 2014: Clinical Respiratory Journal
Krupa R Donga, Shilpa B Donga, Laxmi Priya Dei
Description of Vandhyatva is available in most of the Ayurvedic classics, including Nidana (diagnosis), Samprapti (etiopathogenesis), Lakshana (symptomatology), Bheda (types) and Chikitsa (treatment). In current study, efforts have been made to study the effect of Nasya and Matra Basti on anovulation (Beeja Dushti). Ovulation is under the control of Vata. Narayana Taila is attributed for its effect in Vandhyatva. 24 patients of female infertility having anovulatory factor, being diagnosed by Trans-Vaginal Sonography (TVS) for 2 consecutive cycles were divided in two groups...
January 2013: Ayu
Nikhil M Jirankalgikar, Pankaj B Nariya, Arun V Athavale, Subrata De
BACKGORUND: The three stages of Snehapaka formulations namely Mridu, Madhyama and Khara Paka have been characteristically advocated for different routes of administration-Nasya, Pana/Basti and Abhyanga, respectively. Guidelines or established method for post-formulation characterization for the same is hardly available. OBJECTIVE: The present communication is the comparative study of Mridu, Madhyama and Khara Paka of Panchagavya ghrita (PGG). MATERIALS AND METHODS: Laboratory prepared samples of PGG following classical method were analyzed for different physicochemical, spectroscopic, chromatographic parameters, and antioxidant activity...
April 2013: Journal of Ayurveda and Integrative Medicine
Yiyue Zhang, Gloria E Meredith, Nasya Mendoza-Elias, David J Rademacher, Kuei Y Tseng, Kathy Steece-Collier
We examined the structural plasticity of excitatory synapses from corticostriatal and thalamostriatal pathways and their postsynaptic targets in adult Sprague-Dawley rats to understand how these striatal circuits change in l-DOPA-induced dyskinesias (LIDs). We present here detailed electron and light microscopic analyses that provide new insight into the nature of the structural and synaptic remodeling of medium spiny neurons in response to LIDs. Numerous studies have implicated enhanced glutamate signaling and persistent long-term potentiation as central to the behavioral sensitization phenomenon of LIDs...
July 10, 2013: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
David H Rosmarin, Joseph S Bigda-Peyton, Sarah J Kertz, Nasya Smith, Scott L Rauch, Thröstur Björgvinsson
BACKGROUND: Belief in God is very common and tied to mental health/illness in the general population, yet its relevance to psychiatric patients has not been adequately studied. We examined relationships between belief in God and treatment outcomes, and identified mediating mechanisms. METHODS: We conducted a prospective study with n=159 patients in a day-treatment program at an academic psychiatric hospital. Belief in God, treatment credibility/expectancy, emotion regulation and congregational support were assessed prior to treatment...
April 25, 2013: Journal of Affective Disorders
C Radhika, G Vinod Kumar, K Mihirjan
This work was designed to assess the efficacy of Nasya in reducing the signs and symptoms of cervical spondylosis. The patients attending the O. P. D of Department of Kaya Chikitsa and Panchakarma, Government Ayurveda College Hospital, Thiruvananthapuram were enrolled and subjected to the treatment schedule. Total duration of treatment was 21days. The schedule for the first 14 days was similar in both the groups. It included Rooksha Sveda for 7days followed by Patra Pottali Sveda for 7days. During this period, 90 ml Gandharvahastadi Kashaya twice and Guggulu Tiktaka Kashaya once were given internally...
January 2012: Ayu
Hemanta Kumar Panigrahi
Thirty patients suffering from uncomplicated chronic Sinusitis were enrolled in a clinical study to asses the efficacy of Ayurvedic medicine comprising of Tribhvan kirti rasa (Tablet) along with inhalation of steam of Dasamulakwath (Decoction) followed by nasya (intranasal instillation) with Anu tailam. The Tribhuvan kirti rasa was administered at a dose of 250mg b.d with Adrak swaras (Juice of Ginger).Steam inhalation of Dasmula kwath was given two times a day followed by nasya of Anu tail at a dose of 4 drops in both nostrils...
July 2006: Ancient Science of Life
Varsha Chaudhari, Manjusha Rajagopala, Sejal Mistry, D B Vaghela
Dushta Pratishyaya is the chronic stage of Pratishyaya, which occurs due to neglect or improper management of the disease Pratishyaya. In modern science, chronic sinusitis can be correlated with Dushta Pratishyaya on the basis of the signs, symptoms, complications, and prognosis. Changing lifestyles, rapid urbanization, and the increase in cases of antibiotic resistance are responsible for the rise in the prevalence of sinusitis. In the present clinical study, 37 patients were registered and were randomly divided into three groups: A, B, and C; of the 37 patients, 31 completed the full course of treatment...
July 2010: Ayu
Banamali Das, Ravi M Ganesh, P K Mishra, Gurucharan Bhuyan
Apabahuka is a disease that usually affects the Amsa sandhi (shoulder joint).It is produced by the Vata dosha. Even though the term Apabahuka is not mentioned in the nanatmaja Vata vyadhi, Acharya Sushruta and others have considered Apabahuka as a Vataja vikara. Amsa shosha (wasting of the shoulder) can be considered as the preliminary stage of the disease, where loss or dryness of sleshaka kapha from amsa sandhi occurs. For the present study, Marsha nasya with Laghumasa Taila was administered to 15 patients for seven days, and the following results were obtained...
October 2010: Ayu
Durgesh Prasad Gupta, Manjusha Rajagopala, Kartar Singh Dhiman
Myopia, commonly referred to as shortsightedness, is the most common eye disease in the world with substantial social, educational, and economic impact. Some of the clinical features of Timira can be correlated with myopia. An open randomized clinical trial was conducted to evaluate the role of Tarpana with and without Nasya in patients suffering from myopia. In total, 41 patients were registered in two groups, out of which 30 patients completed the treatment. In Group A, Tarpana with Mahatriphaladya Ghrita and in Group B, Nasya with Abhijita taila followed by Tarpana with Mahatriphaladya Ghrita was administered...
October 2010: Ayu
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