keyword
MENU ▼
Read by QxMD icon Read
search

Salivary gland tumors

keyword
https://www.readbyqxmd.com/read/27898192/reappraising-hyalinizing-clear-cell-carcinoma-a-population-based-study-with-molecular-confirmation
#1
Juan C Hernandez-Prera, Ricky Kwan, Joseph Tripodi, Simion Chiosea, Carlos Cordon-Cardo, Vesna Najfeld, Elizabeth G Demicco
BACKGROUND: Hyalinizing clear cell carcinoma (HCCC) is a rare malignancy, characterized by EWSR1-ATF1 gene fusion, whose behavior is poorly understood, as it was for many years considered a diagnosis of exclusion. METHODS: All available salivary gland carcinomas (n = 594) from our institution were reviewed. Diagnosis of HCCC was confirmed by fluorescence in situ hybridization (FISH) for EWSR1. Literature review was performed. RESULTS: We found 15 patients with HCCCs (10 women, 5 men), 13 with EWSR1 rearrangement...
November 29, 2016: Head & Neck
https://www.readbyqxmd.com/read/27891483/cystadenoma-in-retromolar-region-a-case-report
#2
Sheetal, V Ramesh, P D Balamurali, B Premalatha, Monika Chaudhary
Cystadenoma is a rare benign salivary gland epithelial tumor that is characterized by intraluminal papillary projection. Majority of the tumors are located in minor salivary glands and usually occur in palatal and buccal mucosa, but rarely found in retromolar area. Clinically it is difficult to differentiate it from other minor salivary gland tumors, and diagnosis is chiefly based on characteristic clinical features and immunohistochemistry. We present a case of Cystadenoma arising from the minor salivary gland in retromolar area of a 44 year old female patient with a special emphasis on the immunohistochemistry to rule out the metastatic follicular carcinoma of thyroid...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27891304/metastasis-to-the-oral-soft-tissues-a-review-of-412-cases
#3
REVIEW
Soussan Irani
The present review article analyzes the characteristics of metastases to the oral soft tissues from 1937 to 2015. An extensive literature search was performed. All variables such as age, gender, and primary and secondary tumor sites were analyzed. Metastases to the major salivary glands were not included in this review. In general, there were 412 metastatic lesions developed in the oral soft tissues. The male-to-female ratio was approximately 1.8:1. The mean age of the patients at diagnosis was 58. The lung was the most common primary site and the gingiva was the most common metastatic site...
September 2016: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/27888671/sclerosing-polycystic-adenosis-of-the-parotid-gland-a-systematic-review-and-report-of-2-new-cases
#4
Carlos A Espinosa, Laura Rua, Héctor E Torres, Álvaro Fernández Del Valle, Rui P Fernandes, Juan C Devicente
PURPOSE: We sought to evaluate clinical-epidemiologic aspects, pathologic characteristics, and treatment of sclerosing polycystic adenosis (SPA) of the parotid gland and to report 2 new cases. MATERIALS AND METHODS: We conducted a systematic review following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines for studies published in or before June 2016. The inclusion criteria were as follows: final diagnosis of SPA affecting the parotid gland and articles published in Spanish or English...
November 2, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27888340/prognostic-value-of-comorbidities-in-patients-with-carcinoma-of-the-major-salivary-glands
#5
Christoph Becker, Kilian Konrad Kenjiro Dahlem, Jens Pfeiffer
This study aimed at evaluating the influence of comorbidities on outcome and survival in patients with carcinoma of the major salivary glands. Medical records of 109 patients with carcinoma of the major salivary glands treated at a single quaternary medical care and cancer center between 2003 and 2015 were reviewed. Comorbidities were classified according to the Age-Adjusted Charlson Comorbidity Index (ACCI) scoring system. 59 patients were males, 50 were females. Median age was 69 years and the median interval between tumor diagnosis and date of study inclusion was 71 months...
November 25, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27885457/-psma-targeted-radioligand-therapy-in-prostate-cancer
#6
M M Heck, M Retz, R Tauber, K Knorr, C Kratochwil, M Eiber
Radioligand therapy (RLT) directed against prostate-specific membrane antigen (PSMA) enables tumor-specific treatment directed against PSMA-overexpressing prostate cancer cells. Several PSMA ligands such as PSMA-617 or PSMA-I&T have been developed that can be labeled with β‑radiating lutetium-177. These are currently applied in compassionate use programs to treat metastatic castration-resistant prostate cancer (mCRPC). PSMA-directed RLT is currently being offered in several nuclear medicine departments throughout Germany...
November 24, 2016: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/27882233/high-dose-rate-brachytherapy-for-local-recurrent-adenoid-cystic-carcinoma-of-the-tongue-base-following-postoperative-external-beam-radiotherapy
#7
Sun Young Lee, Jung Soo Kim, Hyoung Cheol Kwon
Adenoid cystic carcinoma is a rare neoplasm commonly originating from the minor salivary glands. The clinical findings typical of this tumor include slow growth, perineural invasion and high frequency of local recurrence. In this study, a patient presented with a tongue base lesion that was treated with surgical excision and additional postoperative external beam radiotherapy. However, local recurrence occurred 8 months after radiotherapy. If recurrence occurs after radiation therapy, total glossectomy should be considered...
November 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27881474/cancer-secretome-may-influence-bsp-and-dsp-expression-in-human-salivary-gland-cells
#8
Samantha Lynn Hamilton, Blake Ferando, Asha Sarah Eapen, Jennifer Chian Yu, Anita Rose Joy
One of the biggest challenges in managing head and neck cancers, especially salivary gland cancers, is the identification of secreted biomarkers of the disease that can be evaluated noninvasively. A relevant source of enriched tumor markers could potentially be found in the tumor secretome. Although numerous studies have evaluated secretomes from various cancers, the influence of the cancer secretome derived from salivary gland cancers on the behavior of normal cells has not yet been elucidated. Our data indicate that secretome derived from salivary gland cancer cells can influence the expression of two potential biomarkers of oral cancer-namely, bone sialoprotein (BSP) and dentin sialoprotein (DSP)-in normal salivary gland cells...
November 23, 2016: Journal of Histochemistry and Cytochemistry: Official Journal of the Histochemistry Society
https://www.readbyqxmd.com/read/27872416/initial-experience-with-ultrasound-elastography-for-diagnosis-of-major-salivary-gland-lesions
#9
Hang Zhou, Xian-Li Zhou, Hui-Xiong Xu, Ya-Ping He, Xiao-Wan Bo, Xiao-Long Li, Bo-Ji Liu, Dan-Dan Li, Dan Wang
OBJECTIVES: The aim of this study was to evaluate the usefulness of ultrasound elastography, including conventional strain elastography, acoustic radiation force impulse (ARFI)-induced strain elastography, and point shear wave elastography (SWE) for diagnosis of major salivary gland lesions. METHODS: Forty major salivary gland lesions underwent conventional sonography, conventional strain elastography, ARFI strain elastography, and point SWE before surgery or biopsy...
December 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/27864182/pleuromediastinal-epithelial-myoepithelial-carcinomas-a-clinicopathologic-and-immunohistochemical-study-of-two-cases
#10
Annikka Weissferdt, Neda Kalhor, Cesar A Moran
OBJECTIVES: Two cases of epithelial-myoepithelial carcinoma are presented, one arising in the pleura and the other in the anterior mediastinum. The cases represent a unique distribution of these tumors within the thoracic cavity. METHODS: Both patients were men aged 25 and 68 years, respectively, who had chest pain and dyspnea. Imaging revealed an anterior mediastinal mass in one patient and a pleural-based tumor in the other. Neither patient had any history of malignancy, and physical examination did not disclose any tumor elsewhere...
November 17, 2016: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/27859477/primary-cutaneous-adenoid-cystic-carcinoma-with-myb-aberrations-report-of-three-cases-and-comprehensive-review-of-the-literature
#11
Carlos N Prieto-Granada, Lei Zhang, Cristina R Antonescu, Jean M Henneberry, Jane L Messina
Adenoid cystic carcinoma (ACC) is a relatively rare slow-growing and often-aggressive epithelial-myoepithelial neoplasm that arises in multiple organs including the skin. The t(6;9) (q22-23;p23-24) translocation, resulting in a MYB-NFIB gene fusion has been found in ACCs from the salivary glands and other organs. Recently, MYB aberrations occurring in a subset (40%) of primary cutaneous ACC (PCACC) examples was described. Herein, we report three additional cases of PCACC harboring MYB aberrations. The tumors presented in three males aged 43, 81 and 55 years old and affected the extremities in the first two patients and the scalp in the third one...
November 8, 2016: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/27847831/relapsed-acinic-cell-carcinoma-of-the-parotid-gland-with-diffuse-distant-metastasis-case-report-with-literature-review
#12
Yousef Khelfa, Munthir Mansour, Yousef Abdel-Aziz, Ali Raufi, Krista Denning, Yehuda Lebowicz
Acinic cell carcinoma (ACC) is an uncommon salivary gland neoplasm that generally displays an indolent growth pattern. Most cases arise in the major glands, particularly the parotid. However, it can arise from minor salivary glands in the oral cavity and aero-digestive tract. Although ACC is generally a low-grade malignant tumor, poorly differentiated and high-grade transformed variants exhibit a propensity for late recurrence and metastasis. There are no adequate clinical trials that define the optimal approach to patients with metastatic salivary gland tumors due to its rarity...
October 2016: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/27846763/outcomes-after-primary-or-adjuvant-radiotherapy-for-salivary-gland-carcinoma
#13
Adam Holtzman, Christopher G Morris, Robert J Amdur, Peter T Dziegielewski, Brian Boyce, William M Mendenhall
BACKGROUND: We report long-term outcomes of patients treated with primary radiotherapy (RT) or surgery and adjuvant RT for salivary gland malignancies. MATERIALS AND METHODS: From 1964 to 2012, 291 patients received primary RT (n = 67) or RT combined with surgery (n = 224). RESULTS: The 5-, 10-, and 15-year local control, local-regional control, distant metastasis-free survival, cause-specific survival and overall survival rates were 82%, 77% and 73%; 77%, 72% and 67%; 74%, 70% and 70%; 70%, 59% and 54%; and 63%, 47% and 38%, respectively...
November 16, 2016: Acta Oncologica
https://www.readbyqxmd.com/read/27843342/the-danish-head-and-neck-cancer-database
#14
REVIEW
Jens Overgaard, Aleksandar Jovanovic, Christian Godballe, Jesper Grau Eriksen
AIM OF THE DATABASE: The Danish Head and Neck Cancer database is a nationwide clinical quality database that contains prospective data collected since the early 1960s. The overall aim of this study was to describe the outcome of the national strategy for multidisciplinary treatment of head and neck cancer in Denmark and to create a basis for clinical trials. STUDY POPULATION: The study population consisted of all Danish patients referred for treatment of squamous cell carcinoma of the larynx, pharynx, oral cavity, or neck nodes from unknown primary or any histopathological type (except lymphoma) of cancer in the nasal sinuses, salivary glands, or thyroid gland (corresponding to the International Classification of Diseases, tenth revision, classifications C...
2016: Clinical Epidemiology
https://www.readbyqxmd.com/read/27822608/expression-of-anoctamins-in-retinal-pigment-epithelium-rpe
#15
Rainer Schreiber, Karl Kunzelmann
The anoctamin (ANO, TMEM16) family of Ca(2+)-activated Cl(-) channels consists of ten members with different cellular functions (ANO1-10). ANO1 is a Ca(2+)-activated Cl(-) channel in secretory epithelial cells of exocrine pancreas, salivary glands, or enterocytes. Expression of ANO1 also promotes cell proliferation and migration of tumor cells. ANO6 is essential for Ca(2+)-dependent scrambling of membrane phospholipids in platelets, red blood cells, and lymphocytes. ANO10 modulates Ca(2+) signals in macrophages and has a role in cerebellar ataxia and other neurological disorders...
November 7, 2016: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/27822066/inhibitory-effects-of-silibinin-on-proliferation-and-lung-metastasis-of-human-high-metastasis-cell-line-of-salivary-gland-adenoid-cystic-carcinoma-via-autophagy-induction
#16
Canhua Jiang, Shufang Jin, Zhisheng Jiang, Jie Wang
OBJECTIVE: To investigate the possible mechanisms and effects of silibinin (SIL) on the proliferation and lung metastasis of human lung high metastasis cell line of salivary gland adenoid cystic carcinoma (ACC-M). METHODS: A methyl thiazolyl tetrazolium assay was performed to detect the inhibitory effects of SIL on the proliferation of ACC-M cells in vitro. Fluorescence microscopy and transmission electron microscopy were used to observe the autophagic process. Western blot was performed to detect the expression of microtube-related protein 1 light-chain 3 (LC3)...
2016: OncoTargets and Therapy
https://www.readbyqxmd.com/read/27822061/clinicopathological-characteristics-treatment-and-survival-outcomes-of-cystadenocarcinoma-of-the-salivary-gland-a-population-based-study
#17
Cheng-Fu Cai, Jia-Yuan Sun, Zhen-Yu He, Huan-Xin Lin, Fa-Rong Liu, Yan Wang
BACKGROUND: The aim of this study was to investigate the clinicopathological characteristics, treatment, and survival of cystadenocarcinoma of the salivary gland. PATIENTS AND METHODS: Cases in the Surveillance, Epidemiology, and End Results database from 1991 to 2012 were identified. Factors significantly associated with survival were identified using Kaplan-Meier survival analysis and Cox proportional hazard regression. RESULTS: A total of 65 patients were identified; of these patients, 64 received surgical treatment, 25 underwent lymphadenectomy, and four (16...
2016: OncoTargets and Therapy
https://www.readbyqxmd.com/read/27806841/diagnostic-pitfalls-of-infarcted-warthin-tumor-in-frozen-section-evaluation
#18
Yaohong Tan, Oleksandr N Kryvenko, Darcy A Kerr, Jennifer R Chapman, Christina Kovacs, David J Arnold, Andrew E Rosenberg, Carmen R Gomez-Fernandez
Warthin tumor (WT) is the second most common benign salivary gland neoplasm and has characteristic cytologic and histologic findings. Fine-needle aspiration is a common and useful preoperative diagnostic technique, which sometimes leads to ischemic injury resulting in the infarction of these lesions. Infarcted WT may demonstrate variable gross and histologic alterations that may render the diagnosis challenging, particularly during intraoperative frozen section evaluation. In this study, we collected 11 resection specimens from 9 patients with infarcted WT...
December 2016: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/27804946/-parosteal-osseous-lipoma-of-the-temporal-bone-concurrent-with-involvement-of-the-parotid-salivary-gland
#19
O V Dolzhansky, E M Pal'tseva, D V Bulanov, D N Fedorov
The paper describes a case of parosteal lipoma of the temporal bone, by simultaneously involving the parotid salivary gland. Computed tomography performed in a 48-year-old man showed that in the area of the posterior edge of the glenoid fossa of the right temporal bone there was a massive (1.5×1.7×0.9-cm) exostosis extending down from the skull base. The exostosis was surrounded by a 3.5×3.6×5.3 soft tissue mass that was located in the projection of the right parotid salivary gland with a capsule and minor calcifications...
2016: Arkhiv Patologii
https://www.readbyqxmd.com/read/27799973/the-oral-pathology-related-articles-published-in-iranian-journal-of-pathology-from-2006-to-2015
#20
Thorakkal Shamim
BACKGROUND: There is a paucity of information about the oral pathology related articles published in a pathology journal. This study aimed to audit the oral pathology related articles published in Iranian Journal of Pathology (Iran J Pathol) from 2006 to 2015. METHODS: Bibliometric analysis of issues of Iran J Pathol from 2006 to 2015 was performed using web-based search. The articles published were analyzed for type of article and individual topic of oral pathology...
2016: Iranian Journal of Pathology
keyword
keyword
37947
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"