Emile Gogineni, Blake E Sells, Khaled Dibs, Sachin R Jhawar, Catherine T Haring, Abberly L Limbach, David J Konieczkowski, Sung J Ma, Simeng Zhu, Sujith Baliga, Darrion L Mitchell, John C Grecula, Marcelo Bonomi, Priyanka Bhateja, Matthew O Old, Nolan B Seim, Stephen Y Kang, James W Rocco, Arnab Chakravarti, Dukagjin M Blakaj, Mauricio E Gamez
BACKGROUND: Salivary duct carcinomas (SDC) are a rare and aggressive subtype of salivary gland neoplasm. They can present with distinct immunoprofiles, such as androgen receptor (AR) and HER-2/Neu-positivity. To date, no consensus exists on how to best manage this entity. METHODS: All patients diagnosed with nonmetastatic AR+ SDC of the parotid from 2013 to 2019 treated with curative intent were included. Immunologic tumor profiling was conducted using 24 distinct markers...
March 19, 2024: Cancers