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Transposition of great

Manavi Tyagi, Theodora Fteropoulli, Catherine S Hurt, Shashivadan P Hirani, Lorna Rixon, Anna Davies, Nathalie Picaut, Fiona Kennedy, John Deanfield, Shay Cullen, Stanton P Newman
OBJECTIVE: We carried out a cross-sectional study to assess cognitive function in a sample of adult CHD patients, within the Functioning in Adult Congenital Heart Disease study London. The association between cognitive functioning and disease complexity was examined. METHODS: A total of 310 patients participated in this study. Patients were classified into four structural complexity groups - tetralogy of Fallot, transposition of the great arteries, single ventricle, and simple conditions...
October 18, 2016: Cardiology in the Young
Rodrigo Rios, Susan R Foerster, Todd M Gudausky
The Melody® transcatheter pulmonary valve system was developed for placement within right ventricle-to-pulmonary artery conduits in patients with CHD for treatment of stenosis or regurgitation, providing an alternative to open-heart surgery. Abnormal systemic venous connections altering the catheter course to the right ventricle-to-pulmonary artery conduit may present a challenge to Melody® valve implantation. We present two such cases, in which the Melody® valve was successfully implanted in teenage patients with congenitally corrected transposition of the great arteries after Senning atrial switch operation...
October 17, 2016: Cardiology in the Young
Matt S Hicks, Reginald S Sauve, Charlene M T Robertson, Ari R Joffe, Gwen Alton, Dianne Creighton, David B Ross, Ivan M Rebeyka
BACKGROUND: Developmental and language outcomes at 2 years of age of children who had arterial switch operation (ASO) for transposition of the great arteries 2004-2010 are described. METHODS: In this prospective cohort study, 91/98 (93 %) children who underwent ASO were assessed at 2 years of age with the Bayley Scales of Infant & Toddler Development-3rd Edition. Outcomes were compared by patient and perioperative variables using bivariate and multivariate regression analyses to identify predictors of language delay...
2016: SpringerPlus
Carla Frescura, Gaetano Thiene
Transposition of the great arteries (TGA) is a cardiac condition in which the arterial trunks arise from the inappropriate ventricle: the aorta from the right ventricle and the pulmonary trunk from the left ventricle [discordant ventriculo-arterial (VA) connection]. In complete TGA, the discordant VA connection is associated with situs solitus or inversus and concordant atrioventricular (AV) connection. The hemodynamic consequence of these combined connections is that systemic and pulmonary circulations function in "parallel" rather than in "series"...
2016: Frontiers in Pediatrics
Tomomi Hasegawa, Munetaka Masuda, Meinoshin Okumura, Hirokuni Arai, Junjiro Kobayashi, Yoshikatsu Saiki, Kazuo Tanemoto, Hiroshi Nishida, Noboru Motomura
OBJECTIVES: Clinical outcomes for neonatal cardiac surgery have improved dramatically over the last decade in Japan; however, few nationwide surveys have been reported in this field. The aim of this study was to investigate the current trends and outcomes of neonatal cardiac surgery in Japan over a period of 15 years. METHODS: All data were derived from the official annual reports by the Japanese Association for Thoracic Surgery (JATS) between 1996 and 2010. Data collected included patient age (neonates, 0-30 days), cardiac diagnosis, operative procedure with or without cardiopulmonary bypass (CPB or non-CPB) and hospital death...
October 2, 2016: European Journal of Cardio-thoracic Surgery
Maulin U Vora, Megan J Christensen, Nicholas W Markin
No abstract text is available yet for this article.
July 12, 2016: Journal of Cardiothoracic and Vascular Anesthesia
Dai Asada, Kazuyuki Ikeda, Masaaki Yamagishi
There are a few reports of successful replacement of the left-sided systemic tricuspid valve with a mechanical valve in small infants with congenitally corrected transposition of the great arteries having Ebstein's anomaly. Tricuspid valve replacement is the preferred option when pulmonary artery banding, performed as a prelude to performing the double-switch operation, is not feasible because of severe heart failure caused by tricuspid regurgitation.
September 29, 2016: Cardiology in the Young
Veysel Tosun, Necmettin Korucuk, Mustafa Mustafa Karakaş, Ünal Güntekin
Congenitally corrected transposition of the great arteries is a rare abnormality accounting for approximately 1% of clinically apparent congenital heart disease. Age at time of diagnosis and survival rate vary and depend on associated anomalies, including pulmonary stenosis, ventricular septal defect, atrial septal defect, atrioventricular block, and atrioventricular valve regurgitation. Reported cases of corrected transposition of the great arteries with single coronary ostium anomaly and atrial septal defect are very rare...
September 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
Claudia Delgado-Corcoran, Katherine H Wolpert, Kathryn Lucas, Stephanie Bodily, Angela P Presson, Susan L Bratton
OBJECTIVE: To determine whether judicious blood testing impacts timing or amount of packed RBC transfusions in infants after heart surgery. DESIGN: A retrospective study comparing before and after initiation of a quality improvement process. SETTING: A university-affiliated cardiac ICU at a tertiary care children's hospital. PATIENTS: Infants less than 1 year old with Risk Adjustment for Congenital Heart Surgery category 4, 5, 6, or d-transposition of great arteries (Risk Adjustment for Congenital Heart Surgery 3) consecutively treated during 2010 through 2013...
September 22, 2016: Pediatric Critical Care Medicine
Kelly Jarvis, Marleen Vonder, Alex J Barker, Susanne Schnell, Michael Rose, James Carr, Joshua D Robinson, Michael Markl, Cynthia K Rigsby
BACKGROUND: Peak velocity measurements are used to evaluate the significance of stenosis in patients with transposition of the great arteries after the arterial switch operation (TGA after ASO). 4D flow cardiovascular magnetic resonance (CMR) provides 3-directional velocity encoding and full volumetric coverage of the great arteries and may thus improve the hemodynamic evaluation in these patients. The aim of this study was to compare peak velocities measured by 4D flow CMR with 2D phase contrast (PC) CMR and the gold standard Doppler echocardiography (echo) in patients with TGA after ASO...
2016: Journal of Cardiovascular Magnetic Resonance
Qing-Yu Wu, Dong-Hai Li, Hui Xue, Zhong-Hua Xu, Hong-Yin Li, Ming-Kui Zhang
No abstract text is available yet for this article.
2016: Chinese Medical Journal
Yoshie Ochiai, Kunihiko Joo, Tatsushi Onzuka, Atsuhiro Nakashima, Yusaku Nagatomo, Mamie Watanabe, Jun Muneuchi
We present a very rare case of bilateral ductus arteriosus in transposition of the great arteries with right aortic arch and aberrant retroesophageal left subclavian artery (SCA). Around 1 month after the successful arterial switch operation, the baby showed wheezing and retractive breathing. The computed tomography revealed that trachea and esophagus were sandwiched between the posterior displaced ascending aorta and the origin of the retroesophageal aberrant left SCA, the so-called Kommerell diverticulum (KD)...
October 2016: Annals of Thoracic Surgery
Richard Van Praagh
The situs, or pattern of anatomic organization, of the subarterial infundibulum and of the great arteries and the degree of development of the subarterial infundibulum largely determine whether the great arteries are normally or abnormally related. There are 2 types of situs: solitus (normal) and inversus (a mirror image of solitus). Situs ambiguus means that the pattern of anatomic organization is uncertain or unknown. Infundibular development varies from absent, to atretic, to severely stenotic, to mildly or moderately stenotic; great arteries are solitus normally related or inversus normally related, respectively...
August 12, 2016: American Journal of Cardiology
Jeremy P Moore, Blandine Mondésert, Michael S Lloyd, Stephen C Cook, Ali N Zaidi, Robert H Pass, Anitha S John, Frank A Fish, Kevin M Shannon, Jamil A Aboulhosn, Paul Khairy
BACKGROUND: Sudden cardiac death is a major contributor to mortality for adults with congenital heart disease. The subcutaneous implantable cardioverter-defibrillator (ICD) has emerged as a novel tool for prevention of sudden cardiac death, but clinical performance data for adults with congenital heart disease are limited. METHODS AND RESULTS: A retrospective study involving 7 centers over a 5-year period beginning in 2011 was performed. Twenty-one patients (median 33...
September 2016: Circulation. Arrhythmia and Electrophysiology
Deana Mikhalkova, Eric Novak, Ari Cedars
In the adult congenital heart disease (ACHD) population, pulmonary valve replacement (PVR) is a common intervention, its benefit, however, has been incompletely investigated. This study investigates short- and intermediate-term outcomes after PVR in ACHD. Using State Inpatient Databases from the Healthcare Cost and Utilization Project, we investigated both hospitalization rate and financial burden accrued over the 12-month period after PVR compared with the 12 months before. Among 202 patients who underwent PVR, per patient-year hospitalization rates doubled in the year after PVR compared with the year before (0...
August 22, 2016: American Journal of Cardiology
L M Silva, I M Kuipers, F van den Heuvel, R Mendes, R M F Berger, I M van Beynum, L Rozendaal, L A J Rammeloo, G G van Iperen, M Schokking, S Frerich, N A Blom, J M P J Breur, W A Helbing
OBJECTIVE: Studies in children with heart disease have been hampered by a lack of easily identifiable patient groups. Currently, there are few prospective population-based registries covering the entire spectrum of heart disease in children. KinCor is a Dutch national registry for children with heart diseases. This paper presents the aims, design and interim results of the KinCor project. METHODS: All children presenting at a Dutch university medical centre with a diagnosis of heart disease from 2012 onwards were eligible for registration in the KinCor database...
November 2016: Netherlands Heart Journal
Vivek Kumar, Sejal Shah
We present a diagnosis of isolated anatomically corrected malposed great arteries on fetal echocardiography at 31 weeks of gestation period. The patient was referred to our institute with a diagnosis of suspected transposition of great arteries.
September 2016: Annals of Pediatric Cardiology
Anita Saxena, Anurag Mehta, Mamta Sharma, Sudha Salhan, Mani Kalaivani, Sivasubramanian Ramakrishnan, Rajnish Juneja
OBJECTIVE: To assess the birth prevalence and pattern of congenital heart disease (CHD) using echocardiography in babies born in a community hospital of North India. METHODS: A cross-sectional observational study conducted over a period of 3 years. Newborns born over a specific 8-h period of the day were recruited in the study. They underwent routine clinical examination and pulse oximetry, followed by screening echocardiography for diagnosing a CHD. RESULTS: A total of 20,307 newborns were screened, among which 874 had abnormal echocardiograms; 687 had insignificant CHDs, 164 had significant CHDs, and 24 had other abnormal cardiac findings...
September 2016: Annals of Pediatric Cardiology
Daniel Forsha, Niels Risum, P Brian Smith, Ronald J Kanter, Zainab Samad, Piers Barker, Joseph Kisslo
BACKGROUND: Patients with systemic right ventricles frequently experience progressive heart failure and conduction abnormalities leading to abnormal ventricular activation. Activation delay-induced mechanical dyssynchrony can contribute to ventricular failure and is identified by a classic strain pattern of paradoxical opposing wall motion that is an excellent predictor of response to cardiac resynchronization therapy in adults with left bundle branch block. The specific aims of this study were to compare right ventricular (RV) mechanics in an adult systemic right ventricle population versus control subjects, evaluate the feasibility of this RV strain pattern analysis, and determine the frequency of the classic pattern...
September 10, 2016: Journal of the American Society of Echocardiography
Sifa Turan, Joshua I Rosenbloom, Mostafa Hussein, Christoph Berg, Ulrich Gembruch, Ahmet A Baschat, Ozhan M Turan
PURPOSE: Fetal head and somatic growth dynamics differs in fetuses with congenital heart defects (CHD). We longitudinally characterized fetal head and somatic growth in relation to the type of CHD. METHODS: Four hundred eleven exams from isolated CHD were compared with 1,219 controls. Head and somatic growth was assessed using head circumference (HC), brain volume (BrV = 1/6 × π × (HC/π)3)/2), fetal cephalization index (FCI = BrV/[estimated fetal weight]), and growth percentile...
September 13, 2016: Journal of Clinical Ultrasound: JCU
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