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https://www.readbyqxmd.com/read/29157128/twenty-four-months-follow-up-of-intravitreal-bevacizumab-injection-versus-intravitreal-triamcinolone-acetonide-injection-for-the-management-of-persistent-non-infectious-uveitic-cystoid-macular-edema
#1
Andrés F Lasave, Ariel Schlaen, David G Zeballos, Manuel Díaz-Llopis, Cristóbal Couto, Wael M El-Haig, J Fernando Arevalo
PURPOSE: To report the efficacy of intravitreal bevacizumab (IVB) injection versus intravitreal triamcinolone acetonide (IVT) for persistent non-infectious uveitic cystoid macular edema (CME). METHODS: Interventional retrospective comparative case series evaluated 37 consecutive patients (44 eyes) with completely controlled uveitis and recalcitrant CME. Patients received repeated injections of 1.25 mg of IVB or 4 mg of IVT. RESULTS: Best-corrected visual acuity (BCVA) at baseline and 24 months was logMAR 1 and 0...
November 20, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29154513/propensity-score-matched-comparison-between-complete-mesocolic-excision-and-classic-right-hemicolectomy-for-colon-cancer-an-italian-and-egyptian-experience
#2
Eva Lieto, Mohamed Abdelkhalek, Michele Orditura, Adel Denewer, Paolo Castellano, Tamer F Youssef, Annamaria Auricchio, Ahmed Setit, Gennaro Galizia
BACKGROUND: The prognosis of right colon cancer remains disappointing. Complete mesocolic excision (CME) with central vascular ligation (CVL), based on the same oncological principles of total mesorectal excision, has been speculated to result in a better outcome. To evaluate the oncological adequacy of CME with CVL, we carried out a comparative study with propensity score-matched analysis between two different surgical procedures performed at Italian and Egyptian University cancer centers...
November 20, 2017: Minerva Chirurgica
https://www.readbyqxmd.com/read/29134948/effect-of-scaffold-morphology-and-cell-co-culture-on-tenogenic-differentiation-of-hadmsc-on-centrifugal-melt-electrospun-poly-l%C3%A2-lactic-acid-fibrous-meshes
#3
Shaohua Wu, Hao Peng, Xiuhong Li, Philipp N Streubel, Yong Liu, Bin Duan
Engineered tendon grafts offer a promising alternative for grafting during the reconstruction of complex tendon tears. The tissue-engineered tendon substitutes have the advantage of increased biosafety and the option to customize their biochemical and biophysical properties to promote tendon regeneration. In this study, we developed a novel centrifugal melt electrospinning (CME) technique, with the goal of optimizing the fabrication parameters to generate fibrous scaffolds for tendon tissue engineering. The effects of CME processing parameters, including rotational speed, voltage, and temperature, on fiber properties (i...
November 14, 2017: Biofabrication
https://www.readbyqxmd.com/read/29134182/high-dose-2-5-mg-intravitreal-bevacizumab-as-rescue-therapy-for-persistent-postradiation-cystoid-macular-edema
#4
Mohammed Ali Khan, Arman Mashayekhi, Kyle Ferguson, Jerry A Shields, Carol L Shields
Background/Aims: To investigate the efficacy of intravitreal high-dose (2.5 mg/0.1 mL) bevacizumab as rescue therapy for postradiation cystoid macular edema (CME) resistant to standard-dose (1.25 mg/0.05 mL) bevacizumab. Methods: Retrospective, interventional case series. Results: Fifteen eyes of 15 patients were included. Eyes were treated with a mean of 10 standard-dose (1.25 mg) bevacizumab injections but failed to show CME resolution. Following 3 monthly treatments of high-dose (2...
September 2017: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29132624/the-value-of-ehr-based-assessment-of-physician-competency-an-investigative-effort-with-internal-medicine-physicians
#5
Kimberly Venta, Erin Baker, Cali Fidopiastis, Kay Stanney
OBJECTIVE: The purpose of this study was to investigate the potential of developing an EHR-based model of physician competency, named the Skill Deficiency Evaluation Toolkit for Eliminating Competency-loss Trends (Skill-DETECT), which presents the opportunity to use EHR-based models to inform selection of Continued Medical Education (CME) opportunities specifically targeted at maintaining proficiency. METHODS: The IBM Explorys platform provided outpatient Electronic Health Records (EHRs) representing 76 physicians with over 5000 patients combined...
December 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29126516/soard-category-1-cme-credit-featured-articles-volume-13-november-2017
#6
(no author information available yet)
No abstract text is available yet for this article.
November 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29120717/cataract-surgery-after-proton-beam-irradiation-for-uveal-tumors
#7
Zeba A Syed, Roberto Pineda
PURPOSE: To study the risks associated with cataract surgery in patients with previous proton-beam irradiation (PBI), focusing on preoperative risk factors, intraoperative findings, and postoperative complications. SETTING: Massachusetts Eye & Ear Infirmary, Boston, Massachusetts, USA. DESIGN: Retrospective case series. METHODS: Electronic medical records of patients who had PBI and cataract surgery between January 1, 2006, and October 1, 2016, were reviewed...
October 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29118565/is-complete-mesocolic-excision-oncologically-superior-to-conventional-surgery-for-colon-cancer-a-retrospective-comparative-study
#8
Christos Agalianos, Nikolaos Gouvas, Christos Dervenis, John Tsiaoussis, George Theodoropoulos, Demetrios Theodorou, George Zografos, Evaghelos Xynos
Background: During the last decade, many efforts have been made in order to improve the oncologic outcomes following colonic resection. Complete mesocolic excision (CME) has proved to provide high rates of disease-free and overall survival rates in patients undergoing resection for colonic malignancies. The aim of our study was to further investigate the role of CME in colonic surgery through comparison with a series of conventional resections. Methods: All data regarding resections for colonic cancer since 2006 were obtained prospectively from two surgical departments...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/29111001/the-professional-practice-and-training-of-neurology-in-the-asian-and-oceanian-region-a-cross-sectional-survey-by-the-asian-and-oceanian-association-of-neurology-aoan
#9
Artemio Roxas, Man Mohan Mehndiratta, Natan Bornstein, Richard Macdonell, Kheng Seang Lim, Ping-Wing Ng, Shuren Dashzeveg, Hidehiro Mizusawa, Hamed Esmatullah, Shey Lin Wu, Christopher Chen, Mohammad Kurniawan, Joung-Ho Rha, Mohammad Wasay, Niphon Poungvarin, Saman Gunatilake, Nguyen Huy Thang
OBJECTIVE: To survey AOAN member countries regarding their organizational structure, postgraduate neurology training program, and resources for neurological care provision. METHODOLOGY: A cross-sectional survey using a 36-item questionnaire was conducted among country representatives to AOAN from August 2015 to August 2016. RESULTS: A total of 18/20 AOAN member countries participated in the survey. All the countries have organized association with regular meetings, election of officers and neurology training program...
November 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29101572/laparoscopic-modified-mesocolic-excision-with-central-vascular-ligation-in-right-sided-colon-cancer-shows-better-short-and-long-term-outcomes-compared-with-the-open-approach-in-propensity-score-analysis
#10
Jung Kyong Shin, Hee Cheol Kim, Woo Yong Lee, Seong Hyeon Yun, Yong Beom Cho, Jung Wook Huh, Yoon Ah Park, Ho-Kyung Chun
BACKGROUND: The introduction of complete mesocolic excision (CME) with central vessel ligation (CVL) for right-sided colon cancer has improved oncologic outcomes. However, there is controversy over the oncologic safety of laparoscopic CME with CVL. This study compared short-term and long-term oncologic outcomes between laparoscopic and open modified CME (mCME) with CVL in patients with right-sided colon cancer. METHODS: We enrolled 1239 patients who underwent open mCME with CVL and 1010 patients treated by a laparoscopic approach for right-side colon cancer between 2000 and 2013 and used 1:1 propensity score matching to adjust for potential baseline confounders between two groups...
November 3, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29098989/an-application-of-the-krylov-fsp-ssa-method-to-parameter-fitting-with-maximum-likelihood
#11
Khanh N Dinh, Roger B Sidje
Monte Carlo methods such as the stochastic simulation algorithm (SSA) have traditionally been employed in gene regulation problems. However, there has been increasing interest to directly obtain the probability distribution of the molecules involved by solving the chemical master equation (CME). This requires addressing the curse of dimensionality that is inherent in most gene regulation problems. The finite state projection (FSP) seeks to address the challenge and there have been variants that further reduce the size of the projection or that accelerate the resulting matrix exponential...
November 3, 2017: Physical Biology
https://www.readbyqxmd.com/read/29095774/cme-review-article
#12
(no author information available yet)
No abstract text is available yet for this article.
November 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29093596/-continuing-medical-education-in-gastroenterology-and-recertification-in-peru
#13
Ofelia Castillo Contreras, César Soriano Álvarez
The field of action of gastroenterology has been expanded due to technological development and the advent of new sub-specialties, such as gastroenterology oncology. Currently, there is no standardization of medical training programs in gastroenterology in our country. The health system and education are changing, so medical practice and competency assessment for medical certification and recertification should reflect these changes. On the other hand, the quality of a specialized unit, service or medical department is directly related to the quality of human resources...
July 2017: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/29092098/differentiated-and-anaplastic-thyroid-carcinoma-major-changes-in-the-american-joint-committee-on-cancer-eighth-edition-cancer-staging-manual
#14
REVIEW
Nancy D Perrier, James D Brierley, R Michael Tuttle
Answer questions and earn CME/CNE This is a review of the major changes in the American Joint Committee on Cancer staging manual, eighth edition, for differentiated and anaplastic thyroid carcinoma. All patients younger than 55 years have stage I disease unless they have distant metastases, in which case, their disease is stage II. In patients aged 55 years or older, the presence of distant metastases confers stage IVB, while cases without distant metastases are further categorized based on the presence/absence of gross extrathyroidal extension, tumor size, and lymph node status...
November 1, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29091337/complete-mesocolic-excision-cme-in-right-sided-colon-cancer-does-not-increase-severe-short-term-postoperative-adverse-events
#15
Richard Bernhoff, Annika Sjövall, Christian Buchli, Fredrik Granath, Torbjörn Hol, Anna Martling
OBJECTIVE: To assess whether Complete Mesocolic Excision (CME) in patients with right sided colon cancer is related to short term mortality or postoperative adverse events requiring reoperation. BACKGROUND: The complete mobilization of an integral mesocolon and central ligation of blood vessels are essential steps in CME-surgery. The resultant specimen, with an intact mesocolic fascia and a high number of harvested lymph nodes is believed to be oncologically favourable...
November 1, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29089928/antimicrobial-and-antibiofilm-effects-of-human-amniotic-chorionic-membrane-extract-on-streptococcus-pneumoniae
#16
Mukesh K Yadav, Yoon Y Go, Shin Hye Kim, Sung-Won Chae, Jae-Jun Song
Background:Streptococcus pneumoniae colonize the human nasopharynx in the form of biofilms. The biofilms act as bacterial reservoirs and planktonic bacteria from these biofilms can migrate to other sterile anatomical sites to cause pneumonia, otitis media (OM), bacteremia and meningitis. Human amniotic membrane contains numerous growth factors and antimicrobial activity; however, these have not been studied in detail. In this study, we prepared amniotic membrane extract and chorionic membrane extract (AME/CME) and evaluated their antibacterial and antibiofilm activities against S...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29089779/online-continuing-medical-education-as-a-key-link-for-successful-noncommunicable-disease-self-management-the-casalud%C3%A2-model
#17
Héctor Gallardo-Rincón, Rodrigo Saucedo-Martínez, Ricardo Mujica-Rosales, Evan M Lee, Amy Israel, Braulio Torres-Beltran, Úrsula Quijano-González, Elena Rose Atkinson, Pablo Kuri-Morales, Roberto Tapia-Conyer
PURPOSE: The purpose of this study is to evaluate how the benefits of online continuing medical education (CME) provided to health care professionals traveled along a patient "educational chain". In this study, the educational chain begins with the influence that CME can have on the quality of health care, with subsequent influence on patient knowledge, disease self-management, and disease biomarkers. METHODS: A total of 422 patients with at least one noncommunicable disease (NCD) treated in eight different Mexican public health clinics were followed over 3 years...
2017: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
https://www.readbyqxmd.com/read/29080485/suppression-of-the-release-of-arsenic-from-arsenopyrite-by-carrier-microencapsulation-using-ti-catechol-complex
#18
Ilhwan Park, Carlito Baltazar Tabelin, Kagehiro Magaribuchi, Kensuke Seno, Mayumi Ito, Naoki Hiroyoshi
Arsenopyrite is the most common arsenic-bearing sulfide mineral in nature, and its weathering contributes to acid mine drainage (AMD) formation and the release of toxic arsenic (As). To mitigate this problem, carrier-microencapsulation (CME) using titanium (Ti)-catechol complex (i.e., Ti-based CME) was investigated to passivate arsenopyrite by forming a protective coating. Ti(4+) ion dissolved in sulfuric acid and catechol were used to successfully synthesize Ti(IV) tris-catecholate complex, [Ti(Cat)3](2-), which was stable in the pH range of 5-12...
October 14, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29078591/laparoscopy-assisted-complete-mesocolic-excision-for-right-hemi-colon-cancer
#19
Chen Su, Xuehui Hong, Xingfeng Qiu
There aren't any standardized ways of controlling operating, although laparoscopic-assisted right-hemi colon cancer complete mesocolic excision (LR-CME), has been widely applied used in China and abroad. Hohenberger gave a new concept that treating complete mesocolic excision (CME) as a colon cancer standard operation for the first time in 2009. And the LR-CME that based on the anatomy of the vascular and level coincide with the concept. One case, male, 69 years old. LR-CME was performed in our department. Following we will introduce correlation experiences and skills of LR-CME...
2017: J Vis Surg
https://www.readbyqxmd.com/read/29075204/human-cardiomyocyte-progenitor-cells-in-co-culture-with-rat-cardiomyocytes-form-a-pro-arrhythmic-substrate-evidence-for-two-different-arrhythmogenic-mechanisms
#20
Nicoline W Smit, Lucia Cócera Ortega, Anna M D Végh, Veronique M F Meijborg, Anke M Smits, Mischa Klerk, Anke J M Tijsen, Hanno L Tan, Marie-José H T Goumans, Gerard J J Boink, Ruben Coronel
Background: Cardiomyocyte progenitor cells (CMPCs) are a promising cell source for regenerative cell therapy to improve cardiac function after myocardial infarction. However, it is unknown whether undifferentiated CMPCs have arrhythmogenic risks. We investigate whether undifferentiated, regionally applied, human fetal CMPCs form a pro-arrhythmic substrate in co-culture with neonatal rat ventricular myocytes (NRVMs). Method: Unipolar extracellular electrograms, derived from micro-electrode arrays (8 × 8 electrodes) containing monolayers of NRVMs (control), or co-cultures of NRVMs and locally seeded CMPCs were used to determine conduction velocity and the incidence of tachy-arrhythmias...
2017: Frontiers in Physiology
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