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https://www.readbyqxmd.com/read/29348102/phytochemical-screening-and-antibacterial-activity-of-cyclamen-persicum-mill-tuber-extracts
#1
Raed Alkowni, Shehdeh Jodeh, Fatima Hussein, Nidal Jaradat
The emerging drug resistance bacteria increased the demand on the discovery of antibiotics from natural sources. This research was aimed to study the antibacterial reactivity; as well as the phytochemicals, of the wild type of Cyclamen persicum, using nine different extraction methods where four solvents (Methanol, Ethanol, Hexane; and Water) were involved with varied extraction periods ranged from 2 up to 10 hours. The antibacterial activity of crude methanol extract (CME) was found as the best method of extraction, with particular emphasis on the method with prolonged extraction time of (10 hrs)...
January 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29345880/strategies-for-managing-patients-with-depression-who-are-experiencing-cognitive-impairment
#2
Larry Culpepper
Pronounced deficits in executive function are found in up to one-third of patients with MDD, and this impairment can keep patients from achieving full functional recovery. In this CME activity, review the evidence regarding the effectiveness of available interventions to improve cognitive dysfunction in patients with MDD.
November 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29345879/improving-long-term-outcomes-in-patients-with-schizophrenia-what-is-the-evidence-for-long-acting-injectable-antipsychotics
#3
Diana O Perkins
Do you consider long-acting injectable (LAI) antipsychotics when selecting among treatments for schizophrenia? Take part in this CME activity to review the evidence for LAIs vs oral medications and to learn which patients may benefit most from this treatment option. Plus, discover the pharmacokinetic properties of LAIs and barriers to their use.
November 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29345878/impact-of-cognitive-impairment-on-functioning-in-patients-with-depression
#4
Raymond W Lam
Reassessing a patient's diagnosis if he or she does not respond adequately to initial antidepressant pharmacotherapy is imperative. In this CME activity, evaluate the case of Melissa, a 32-year-old architect with a potential case of treatment-resistant depression, and decide on appropriate treatment strategies.
November 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29345877/comparing-treatments-for-tardive-dyskinesia
#5
Leslie L Citrome
Many treatment interventions for tardive dyskinesia have been studied, but some have better evidence than others. Read this CME activity to get an expert's perspectives on the evidence for older and newer treatments so that you can minimize abnormal movements in your patients.
November 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29345876/assessing-patients-for-tardive-dyskinesia
#6
John M Kane
Do you regularly screen for tardive dyskinesia in at-risk patients? Explore this CME activity by a well-known expert for information on rating scales for screening, available diagnostic criteria, assessment tips, and monitoring recommendations.
November 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29345875/available-tools-for-assessing-cognitive-impairment-in-major-depressive-disorder
#7
Roger S McIntyre
You know that measuring cognition in your patients with depression is important. But cognitive assessment instruments can be difficult to access, expensive, time consuming, and not available in an electronic format. Read this CME activity to learn about a new free tool.
November 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29345874/epidemiology-and-prevention-of-tardive-dyskinesia
#8
Christoph U Correll
What risk factors suggest that patients are more likely to develop tardive dyskinesia (TD)? Can TD symptoms be prevented? Read this CME activity to learn about the prevalence, epidemiology, and prevention of these abnormal movements from an expert.
November 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29344488/intravitreal-aflibercept-as-rescue-therapy-for-post-radiation-cystoid-macular-edema-resistant-to-intravitreal-bevacizumab-outcomes-at-1-year
#9
Mohammed Ali Khan, Arman Mashayekhi, Jerry A Shields, Carol L Shields
Background/Aims: To investigate the efficacy of intravitreal aflibercept as rescue therapy for post-radiation cystoid macular edema (CME) resistant to prior treatment with intravitreal bevacizumab (IVB). Methods: Retrospective, interventional, case-controlled series. Eyes with persistent post-radiation CME were treated with intravitreal aflibercept (2 mg/0.05 mL). Central macular thickness (CMT) and visual acuity were compared to a matched control group treated with only IVB at 1 year...
November 2017: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29341086/clinical-issues-january-2018-1-2-www-aornjournal-org-content-cme
#10
Julie Cahn, Sharon A Van Wicklin
No abstract text is available yet for this article.
January 2018: AORN Journal
https://www.readbyqxmd.com/read/29341083/factors-contributing-to-perioperative-medication-errors-a-systematic-literature-review-2-1-www-aornjournal-org-content-cme
#11
Julie Boytim, Beth Ulrich
No abstract text is available yet for this article.
January 2018: AORN Journal
https://www.readbyqxmd.com/read/29341074/back-to-basics-the-universal-protocol-1-4-www-aornjournal-org-content-cme
#12
Lisa Spruce
No abstract text is available yet for this article.
January 2018: AORN Journal
https://www.readbyqxmd.com/read/29339307/anticoccidial-activity-of-fruit-peel-of-punica-granatum-l
#13
Shazia Ahad, Syed Tanveer, Tauseef Ahmad Malik, Irshad Ahmad Nawchoo
In the interests of food safety and public health, plants and their compounds are now re-emerging as an alternative approach to treat parasitic diseases. Here, we studied the anticoccidial effect of different solvent extracts of the fruit peel of Punica granatum-a commercial waste from pomegranate juice industries. The hope underlying these experiments was to find a sustainable natural product for controlling coccidiosis. The plant extracts were prepared using solvents of different polarity. Acute oral toxicity study was first carried out to see the safety of crude extracts...
January 12, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29336342/-homogeneity-of-the-european-training-program-the-role-of-the-european-board-of-urology
#14
José Luís Domínguez Escrig
From its origins and acting through its specific committees, the E.B.U. has been dedicated to the improvement and standardization of urological training across Europe. Identifying minimal requirements for urology training, publishing a European Curriculum and defining basic rules for accreditation of educational activities, hence, offering a systematic assessment for the recognition of quality. Working through different dedicated committees, the E.B.U. oversees every aspect on the urological training in Europe...
January 2018: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/29328043/complementary-and-alternative-medicine-and-medical-education-in-georgia-state-of-the-art-and-further-perspectives
#15
I Nadareishvili, K Lunze, G Pkhakadze, N Japiashvili, N Tabagari
Aim - complementary and alternative medicine (CAM) is popular in Georgia, but providers' training not well understood or regulated. The aim of this mixed-methods study was to inform the process of implementing quality CAM curricula in Georgia and strategies for the inclusion of effective CAM curricula into medical education in Georgia. We analyzed existing medical curricula. We conducted a contextual analysis based of qualitative data collected from relevant medical education experts, qualified physicians, CAM practitioners and other stakeholders; and administered a quantitative MD students' survey to MD students...
December 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29322707/knowledge-attitudes-beliefs-and-practices-of-physicians-regarding-idiopathic-pulmonary-fibrosis-and-the-impact-of-a-continuing-medical-education-program
#16
Sahajal Dhooria, Inderpaul Singh Sehgal, Ritesh Agarwal, Ashutosh Nath Aggarwal, Digambar Behera
Background: Significant deficiencies have been identified previously in the knowledge of physicians regarding the current diagnosis and management of idiopathic pulmonary fibrosis (IPF). Whether a continuing medical education (CME) program helps in overcoming these deficiencies has never been studied. Methods: This was a questionnaire-based study performed to assess the knowledge, attitudes, beliefs and practices of physicians regarding IPF before and after attending a CME program at a tertiary care teaching Institute in northern India...
November 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29311433/local-viscoelastic-response-of-direct-and-indirect-dental-restorative-composites-measured-by-afm
#17
Laura Grattarola, Giacomo Derchi, Alberto Diaspro, Carla Gambaro, Marco Salerno
We investigated the viscoelastic response of direct and indirect dental restorative composites by the novel technique of AM-FM atomic force microscopy. We selected four composites for direct restorations (Adonis, Optifil, EPH, CME) and three composites for indirect restorations (Gradia, Estenia, Signum). Scanning electron microscopy with micro-analysis was also used to support the results. The mean storage modulus of all composites was in the range of 10.2-15.2 GPa. EPH was the stiffest (p<0.05 vs. all other composites but Adonis and Estenia), while no significant difference was observed between direct and indirect group (p≥0...
December 31, 2017: Dental Materials Journal
https://www.readbyqxmd.com/read/29303704/golimumab-in-refractory-uveitis-associated-to-juvenile-idiopathic-arthritis-multicentre-study-of-7-cases-and-literature-review
#18
REVIEW
Natalia Palmou-Fontana, Vanesa Calvo-Río, José Luis Martín-Varillas, Carlos Fernández-Díaz, Marina Mesquida, Alfredo Adán, María Victoria Hernández, Miguel Cordero-Coma, Olga Maiz Alonso, David Díaz-Valle, Carlos Fernández-Cid, Oscar Ruiz-Moreno, José Luis Hernández, Miguel Angel González-Gay, Ricardo Blanco
OBJECTIVES: To assess the efficacy of golimumab (GLM), a fully humanised anti-TNF-α monoclonal antibody, in refractory juvenile idiopathic arthritis (JIA)-associated uveitis. METHODS: This was a multicentre study of JIA-associated uveitis refractory to standard synthetic immunosuppressive drugs and in most cases to other anti-TNF-α agents. Results were expressed as mean±standard deviation or as median (range or interquartile range). The Wilcoxon signed-rank test was used to compare continuous variables...
December 15, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29298168/incidence-of-cystoid-macular-edema-after-descemet-membrane-endothelial-keratoplasty
#19
Viridiana Kocaba, Romain Mouchel, Jacques Fleury, Anne-Sophie Marty, Hélène Janin-Manificat, Delphine Maucort-Boulch, Carole Burillon
PURPOSE: The incidence of and risk factors for cystoid macular edema (CME) after Descemet membrane endothelial keratoplasty (DMEK) remain uncertain. This study examines the incidence of and risk factors for CME after DMEK. METHODS: This retrospective, single-center study included patients with no history of CME who had undergone DMEK. Patients were examined weekly for 1 month after surgery and at 3 and 6 months after surgery. Follow-up examinations included visual acuity (VA) assessment, pachymetry, anterior segment optical coherence tomography, biomicroscopy, intraocular pressure measurement, and fundoscopy...
January 2, 2018: Cornea
https://www.readbyqxmd.com/read/29296947/detectable-clonal-mosaicism-in-blood-as-a-biomarker-of-cancer-risk-in-fanconi-anemia
#20
Judith Reina-Castillón, Roser Pujol, Marcos López-Sánchez, Benjamín Rodríguez-Santiago, Miriam Aza-Carmona, Juan Ramón González, José Antonio Casado, Juan Antonio Bueren, Julián Sevilla, Isabel Badel, Albert Català, Cristina Beléndez, María Ángeles Dasí, Cristina Díaz de Heredia, Jean Soulier, Detlev Schindler, Luis Alberto Pérez-Jurado, Jordi Surrallés
Detectable clonal mosaicism for large chromosomal events has been associated with aging and an increased risk of hematological and some solid cancers. We hypothesized that genetic cancer predisposition disorders, such as Fanconi anemia (FA), could manifest a high rate of chromosomal mosaic events (CMEs) in peripheral blood, which could be used as early biomarkers of cancer risk. We studied the prevalence of CMEs by single-nucleotide polymorphism (SNP) array in 130 FA patients' blood DNA and their impact on cancer risk...
January 24, 2017: Blood Advances
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