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https://www.readbyqxmd.com/read/28544601/the-impact-of-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features-on-the-performance-of-the-afirma-gene-expression-classifier
#1
Jen-Fan Hang, William H Westra, David S Cooper, Syed Z Ali
BACKGROUND: A recent revision in thyroid tumor nomenclature has resulted in a change from a malignant diagnosis (noninvasive follicular variant of papillary thyroid carcinoma) to one that is nonmalignant (noninvasive follicular thyroid neoplasm with papillary-like nuclear features [NIFTP]). The objective of the current study was to evaluate the impact of this change on the performance of the Afirma gene expression classifier (GEC). METHODS: The authors retrospectively analyzed consecutive thyroid fine-needle aspiration specimens with indeterminate diagnoses on which GEC was performed...
May 24, 2017: Cancer
https://www.readbyqxmd.com/read/28525663/management-of-male-and-female-neurogenic-stress-urinary-incontinence-in-spinal-cord-injured-sci-patients-using-adjustable-continence-therapy
#2
Enrico Ammirati, Alberto Manassero, Alessandro Giammò, Roberto Carone
INTRODUCTION: Artificial urinary sphincter (AUS) is an option for the treatment of neurogenic stress urinary incontinence (nSUI), but complications and re-operation rates are high, and there is no clear indication from guidelines (1). The aim of our study is to evaluate the effectiveness of a less invasive continence device in neurogenic population: Adjustable Continence Therapy ProACT/ACT®. METHODS: We retrospectively includedpatients with spinal cord injuries in this study, complaining of nSUI and treated at our Institution with Pro-ACT/ACT® implantation...
May 16, 2017: Urologia
https://www.readbyqxmd.com/read/28504830/exploring-planar-chiral-amino-siloxides
#3
Christopher Golz, Patricia Steffen, Carsten Strohmann
Die Synthese, Struktur und exemplarische Reaktivität von Siloxiden mit planarchiralen N,N-Dimethylaminomethylferrocen-Rückgrat wird vorgestellt. Mehrere Zinkkomplexe ausgehend aus dem racemischen als auch dem enantiomerenreinen Silanol wurden in Gegenwart von Wasser synthetisiert, kristallographisch charakterisiert und ihr Verhalten in Lösung untersucht. Die in diesem System vorhandene chirale Sonde stellt sich als wertvolles Werkzeug zur Identifizierung der vorliegenden Struktur in Lösung heraus. Weiterhin zeigen die Zinksiloxide eine vergleichbare Reaktivität wie die korrespondierenden Silanole, daher bieten sich diese als "maskierte" Silanole an, vor allem dann, wenn die Silanole präparativ unzugänglich sind...
May 15, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28493558/comparison-of-risk-of-malignancy-in-a-subgroup-with-atypia-of-undetermined-significance-follicular-lesion-of-undetermined-significance-a-meta-analysis
#4
REVIEW
Soon-Hyun Ahn, Seong Dong Kim, Woo-Jin Jeong
BACKGROUND: As heterogeneous findings are included in the atypia of undetermined significance (AUS)/follicular lesion of undetermined significance (FLUS) category, differing risks of malignancy in subgroups have been reported in several articles. METHODS: We performed a meta-analysis of full-text publications written in English found in the Embase and PubMed databases. RESULTS: The 4-tiered subgroup proportion meta-analysis showed that the 95% confidence interval (95% CI) of the risk of malignancy in the cellular atypia group did not overlap with the other 3 subgroups and demonstrated a significant difference...
May 11, 2017: Head & Neck
https://www.readbyqxmd.com/read/28488195/differences-in-clinical-features-between-subcategories-of-atypia-follicular-lesion-of-undetermined-significance
#5
Seong Dong Kim, Seung Hoon Han, Woo-Jin Jeong, Hyojin Kim, Soon Hyun Ahn
Within the Bethesda System for Reporting Thyroid Cytopathology (TBSRTC), category III (atypia or follicular lesion of undetermined significance (AUS/FLUS)) comprises specimens with heterogeneous features and the need for subcategorization has been reported. We compared the clinical features of two subgroups from within the category of AUS/FLUS to determine precise guidelines for clinicians who explain the results of fine-needle aspiration (FNA) to patients. Retrospective review was performed including data from all patients who underwent FNA with results reported as AUS/FLUS at a single tertiary hospital from January 2010 to August 2014...
May 9, 2017: Endocrine Pathology
https://www.readbyqxmd.com/read/28480631/incidence-and-significance-of-true-papillae-in-thyroid-fine-needle-aspiration
#6
Andrew A Renshaw, Edwin W Gould
INTRODUCTION: Whether true papillae without nuclear features of papillary carcinoma in thyroid fine needle aspirates should be diagnosed as atypia of undetermined significance (AUS) is unclear. METHODS: The results of all thyroid FNAs performed from 2014-2016 with corresponding resections as well as aspirates from 2000-2016 with a diagnosis of follicular variant of papillary carcinoma or Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) were reviewed...
May 7, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28479079/are-urine-cultures-necessary-prior-to-urologic-prosthetic-surgery
#7
REVIEW
Nicholas L Kavoussi, Boyd R Viers, Travis J Pagilara, Jordan A Siegel, Matthias D Hofer, Billy Cordon, Nabeel Shakir, Jeremy Scott, Allen F Morey
INTRODUCTION: A preoperative negative urine culture is generally advised before implantation of urologic prosthetics to prevent device infection. However, a review of the medical literature indicates sparse evidence to support this practice. AIM: To describe outcomes for patients undergoing prosthetic implantation without preoperative urine cultures. METHODS: The cases of men undergoing artificial urinary sphincter (AUS) and/or inflatable penile prosthesis (IPP) placement at a tertiary care center from 2007 through 2015 were reviewed...
May 3, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28478890/bericht-aus-der-praxis-practice-report-tutor-training-for-a-peer-assisted-interprofessional-communication-seminar-a-work-in-progress
#8
Jan Hundertmark, Angelika Homberg, Simone Alvarez, Heike Lauber, Sarah Berger, Christiane Büscher, Jobst-Hendrik Schultz, Cornelia Mahler
A novel peer-led communication seminar for medical students and for students of the Interprofessional Health Care B.Sc. degree programme at the Medical Faculty of Heidelberg is currently being developed to address the increasing need for interprofessional collaborative competencies in health care professionals. The core elements of this course include role plays in interprofessional communication situations, patient-centred professional practice, and reflections on underlying attitudes. Each seminar will be conducted by a team of two senior students from both undergraduate programmes, practising their new roles as interprofessional tutors and, at the same time, serving as competent role models for interprofessional collaboration...
May 3, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28475032/molecular-characterization-of-candidatus-borrelia-tachyglossi-family-spirochaetaceae-in-echidna-ticks-bothriocroton-concolor
#9
Siew-May Loh, Amber Gillett, Una Ryan, Peter Irwin, Charlotte Oskam
Recently, a novel species of the genus Borreliawas identified in Bothriocroton concolor and Ixodes holocyclus ticks from echidnas. Analyses of 16S rRNA and flaB genes identified three closely related genotypes of this bacterium (Borrelia sp. Aus A-C) that were unique and distinct from previously described borreliae. Phylogenetic analyses of flaB (763 bp), groEL (1537 bp), gyrB (1702 bp) and glpQ (874 bp) gene sequences and concatenated sequences (3585 bp) of three gene loci (16S rRNA, flaB and gyrB) were consistent with previous findings and confirm that this novel species of the genus Borrelia is more closely related to, yet distinct from, the Reptile-associated (REP) and Relapsing Fever (RF) groups...
April 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28463597/cytology-ultrasonography-risk-stratification-scoring-system-based-on-fine-needle-aspiration-cytology-and-the-korean-thyroid-imaging-reporting-and-data-system
#10
Min Ji Hong, Dong Gyu Na, Jung Hwan Baek, Jin Yong Sung, Ji-Hoon Kim
BACKGROUND: The malignancy risk of a cytology diagnosis may depend on the ultrasonography (US) patterns of thyroid nodules, and management should be determined by the combined malignancy risk of fine-needle aspiration (FNA) cytology and US patterns. This study was performed to develop a clinically applicable cytology-ultrasonography (CU) scoring system for malignancy risk stratification based on FNA cytology and US patterns, according to the Korean-Thyroid Imaging Reporting and Data System (K-TIRADS)...
May 19, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28463595/selection-of-atypia-follicular-lesion-of-unknown-significance-patients-for-surgery-versus-active-surveillance-without-using-genetic-testing-a-single-institute-experience-prospective-analysis-and-recommendations
#11
Oded Cohen, Sharon Tzelnick, Yonatan Lahav, Doron Schindel, Doron Halperin, Moshe Yehuda
Atypia/follicular lesion of unknown significance (AUS/FLUS) has variable rates of malignancy. The recommended management includes active surveillance (AS), repeated fine needle aspiration (RFNA), diagnostic surgery or genetic testing for malignancy. The objective of this study was to assess the management of AUS/FLUS patients in a dedicated thyroid clinic without implementing genetic testing. This is a single institute cohort study of all patients aged 18 years and above who underwent ultrasound-guided FNA (USGFNA) thyroid biopsies between January 2009 and January 2013 and were followed until January 2016...
May 2, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28434295/standard-heart-failure-medication-in-cardiac-transthyretin-amyloidosis-useful-or-harmful
#12
Fabian Aus dem Siepen, Selina Hein, Ralf Bauer, Hugo A Katus, Arnt V Kristen
No abstract text is available yet for this article.
March 2017: Amyloid: the International Journal of Experimental and Clinical Investigation
https://www.readbyqxmd.com/read/28434136/facial-expressions-and-speech-acts-experimental-evidences-on-the-role-of-the-upper-face-as-an-illocutionary-force-indicating-device-in-language-comprehension
#13
Filippo Domaneschi, Marcello Passarelli, Carlo Chiorri
Language scientists have broadly addressed the problem of explaining how language users recognize the kind of speech act performed by a speaker uttering a sentence in a particular context. They have done so by investigating the role played by the illocutionary force indicating devices (IFIDs), i.e., all linguistic elements that indicate the illocutionary force of an utterance. The present work takes a first step in the direction of an experimental investigation of non-verbal IFIDs because it investigates the role played by facial expressions and, in particular, of upper-face action units (AUs) in the comprehension of three basic types of illocutionary force: assertions, questions, and orders...
April 22, 2017: Cognitive Processing
https://www.readbyqxmd.com/read/28425211/importance-of-cytological-subclassification-of-thyroid-nodules-with-bethesda-category-iii-cytology-aus-flus-into-architectural-atypia-only-and-nuclear-atypia-a-prospective-study
#14
Pedro Weslley Rosario, Maria Regina Calsolari
BACKGROUND: The objective of this study was to compare two cytological subcategories of thyroid nodules with Bethesda category III initial cytology. METHODS: This was a prospective study. All patients with thyroid nodules > 1 cm were eligible and 98 patients with category III cytology were selected. Cytology was subcategorized into architectural atypia only (AA, n = 45) and nuclear atypia (NA, n = 53). All patients underwent a second fine-needle aspiration (FNA)...
April 19, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28422844/ultrasound-is-helpful-to-differentiate-bethesda-class-iii-thyroid-nodules-a-prisma-compliant-systematic-review-and-meta-analysis
#15
REVIEW
Lu-Ying Gao, Ying Wang, Yu-Xin Jiang, Xiao Yang, Ru-Yu Liu, Xue-Hua Xi, Shen-Ling Zhu, Rui-Na Zhao, Xing-Jian Lai, Xiao-Yan Zhang, Bo Zhang
BACKGROUND: Fine-needle aspiration (FNA) is the most dependable tool to triage thyroid nodules for medical or surgical management. However, Bethesda class III cytology, namely "follicular lesion of undetermined significance" (FLUS) or "atypia of undetermined significance" (AUS), is a major limitation of the US-FNA in assessing thyroid nodules. As the most important imaging method, ultrasound (US) has a high efficacy in diagnosing thyroid nodules. This meta-analysis aimed to assess the role of US in evaluating Bethesda class III thyroid nodules...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28422502/arrays-of-ag-and-au-nanoparticles-with-terpyridine-and-thiophene-based-ligands-morphology-and-optical-responses
#16
Markéta Prusková, Veronika Sutrová, Miroslav Šlouf, Blanka Vlčková, Jiří Vohlídal, Ivana Šloufová
The assembly of Ag and Au nanoparticles (NPs) into nanoparticulate arrays mediated by terpyridine (tpy), 4'-(2-thienyl)terpyridine (T-tpy), and short α,ω-bis(tpy)oligothiophene ligands has been accomplished at the interface between the Ag or Au NP hydrosol and a solution of the molecular species in dichloromethane. The relationship between the morphology and the optical responses of the arrays has been investigated by advanced methods of TEM (transmission electron microscopy) image analysis and surface plasmon extinction (SPE) spectra...
April 19, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28416930/what-are-the-prevalence-of-abdominal-aortic-aneurysm-in-patients-with-chronic-obstructive-pulmonary-diseases-and-the-characteristics-of-these-patients
#17
Ulku Aka Akturk, Nagihan Durmus Kocak, Suleyman Akturk, Mert Dumantepe, Aysun Sengul, Mehmet Arif Akcay, Makbule Ozlem Akbay, Feyyaz Kabadayi, Dilek Ernam
OBJECTIVE: To determine the prevalence of abdominal aortic aneurysm (AAA) in patients with chronic obstructive pulmonary disease (COPD) and to assess the characteristics of these patients. MATERIALS AND METHODS: Stable COPD patients (age, >40 years) were included in the study between January 2014 and June 2014. Patients with acute exacerbations and a previous lung resection were excluded. Data regarding demographic characteristics were recorded. The modified Medical Research Council (mMRC) dyspnea scale was used to assess the severity of breathlessness...
February 2017: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/28407624/risk-of-malignancy-and-risk-of-neoplasia-in-the-bethesda-indeterminate-categories-study-on-4-532-thyroid-fine-needle-aspirations-from-a-single-institution-in-india
#18
Swati Mahajan, Radhika Srinivasan, Arvind Rajwanshi, Bishan Radotra, Naresh Panda, Pranab Dey, Nalini Gupta, Raje Nijhawan
OBJECTIVES: To determine the frequency of category 3 (atypia of undetermined significance [AUS]/follicular lesion of undetermined significance [FLUS]), category 4 (follicular neoplasm), and category 5 (suspicious for malignancy) of The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC), the risk of malignancy (ROM) and the risk of neoplasia (RON) in these categories. STUDY DESIGN: A retrospective 6-year audit of 4,532 thyroid fine-needle aspirations (FNA) reported as per the TBSRTC from a single institution with cytohistological correlation in 335 cases...
2017: Acta Cytologica
https://www.readbyqxmd.com/read/28407552/physician-patient-communication-at-diagnosis-of-type-2-diabetes-and-its-links-to-patient-outcomes-new-results-from-the-global-introdia%C3%A2-study
#19
William H Polonsky, Matthew Capehorn, Anne Belton, Susan Down, Aus Alzaid, Victoria Gamerman, Friedericke Nagel, Jisoo Lee, Steven Edelman
AIMS: To investigate patient experiences during the diagnosis of type 2 diabetes mellitus (T2DM), focusing on how physician-patient communication at diagnosis influences patients' psychosocial stress and subsequent self-management and outcomes. METHODS: We surveyed adults with T2DM in 26 countries in a large cross-national study of physician-patient communication during early T2DM treatment (IntroDia®). The self-report questionnaire assessed retrospectively patient experiences during diagnosis conversations (focusing on 43 possible conversational elements, and communication quality) and potential effects on patient-reported outcomes...
March 22, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28399533/-naturheilkunde-und-komplement%C3%A3-re-verfahren-in-der-nationalen-versorgungsleitlinie-%C3%A2-nicht-spezifischer-kreuzschmerz%C3%A2-erfahrungen-aus-der-%C3%A2-k%C3%A3-nigsklasse%C3%A2
#20
Anna K Koch, Petra Klose Klose, Gustav Dobos, Holger Cramer, Jost Langhorst
No abstract text is available yet for this article.
2017: Complementary Medicine Research
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