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https://www.readbyqxmd.com/read/28794592/radiotherapy-is-associated-with-reduced-continence-outcomes-following-implantation-of-the-artificial-urinary-sphincter-in-men-with-post-radical-prostatectomy-incontinence
#1
Stephanie Guillaumier, Eskinder Solomon, Julie Jenks, Mahreen Pakzad, Rizwan Hamid, Jeremy Ockrim, Julian Shah, Tamsin Greenwell
OBJECTIVES: The objective of this study is to present the outcomes of men undergoing implantation of artificial urinary sphincter, after treatment for prostate cancer and also to determine the effect of radiotherapy on continence outcomes after artificial urinary sphincter (AUS) implantation. MATERIALS AND METHODS: A prospectively acquired database of all 184 patients having AUS insertion between 2002 and 2012 was reviewed, and demographic data, mode of prostate cancer treatment(s) before implantation, and outcome in terms of complete continence (pad free, leak free) were assessed...
July 2017: Urology Annals
https://www.readbyqxmd.com/read/28791230/contemporary-surgical-devices-for-male-stress-urinary-incontinence-a-review-of-technological-advances-in-current-continence-surgery
#2
REVIEW
Eric Chung
Male stress urinary incontinence (SUI) remains a debilitating condition that adversely impacts all domains of quality of life and is associated with significant social stigma and health economic burden. The incidence of post-prostatectomy urinary incontinence (PPI) depends on the definition of urinary incontinence and the length of patient follow up. In patients with persistent PPI following failure of conservative measures, surgical treatment is recommended although there is no published guideline on when surgery should be performed, and what the best surgical option is...
July 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28791228/management-of-bladder-neck-stenosis-and-urethral-stricture-and-stenosis-following-treatment-for-prostate-cancer
#3
REVIEW
Helen L Nicholson, Yasser Al-Hakeem, Javier J Maldonado, Vincent Tse
The aim of this review is to examine all urethral strictures and stenoses subsequent to treatment for prostate cancer, including radical prostatectomy (RP), radiotherapy, high intensity focused ultrasound (HIFU) and cryotherapy. The overall majority respond to endoscopic treatment, including dilatation, direct visual internal urethrotomy (DVIU) or bladder neck incision (BNI). There are adjunct treatments to endoscopic management, including injections of corticosteroids and mitomycin C (MMC) and urethral stents, which remain controversial and are not currently mainstay of treatment...
July 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28789963/detection-of-prostate-cancer-risk-factor-immunosensor-based-deposition-of-graphene-layer-decorated-gold-nanoparticles
#4
Mintu Pal, Raju Khan
In this work, we report a novel electrochemical immunosensorbased on gold nanoparticles deposited on the surface of graphene layers to detect prostate-specific antigen (PSA), a valuable biomarker for early detection of prostate cancer. The biosensor was fabricated using gold nanoparticles supported graphene oxide (Au-GrO) nanocomposite on platinum electrode and was used for immobilization of monoclonal anti-PSA antibody via EDC/NHS coupling method. To confirm the functionality of the antibody, we performed immunofluorescence staining using human normal prostate epithelial cells, RWPE-1...
August 5, 2017: Analytical Biochemistry
https://www.readbyqxmd.com/read/28783634/nonnegative-decompositions-for-dynamic-visual-data-analysis
#5
Lazaros Zafeiriou, Yannis Panagakis, Maja Pantic, Stefanos Zafeiriou
The analysis of high-dimensional, possibly temporally misaligned, time-varying visual data is a fundamental task in disciplines such as image, vision, and behaviour computing. In this paper, we focus on dynamic facial behaviour analysis and in particular on the analysis of facial expressions. Distinct from the previous approaches, where sets of facial landmarks are used for face representation, raw pixel intensities are exploited for 1) unsupervised analysis of the temporal phases of facial expressions and facial action unitis (AUs) and 2) temporal alignment of a certain facial behaviour displayed by two different persons...
August 2, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28760684/bericht-aus-der-praxis-practice-report-how-to-establish-pal-successfully-in-medical-education-ten-tips-for-successful-courses-in-a-peer-assisted-learning-pal-format-in-undergraduate-medical-education-ugme
#6
Matthias Hofer, Kathrin Klein, Bastian Malzkorn, Alice Martin, Christian Weigel, Ole Martin
This article aims to provide useful suggestions for the implementation of new courses in a PAL-format in undergraduate medical education (UGME). It presents 10 key tips on: needs assessment, clarification of goals and objectives for internal marketing, the choice of teaching formats, fund raising, recruiting of educators, qualification of peer tutors, the fun factor, how to establish a structured and longitudinal curriculum, assessment methods and motivation, collecting feedback and the use of its results. These 10 tips are linked to scientific evidence in the educational literature and elucidated by specific examples, based upon a major PAL-project on diagnostic imaging, which can be transferred to other teaching topics as well...
July 28, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28743562/robotic-assisted-laparoscopic-artificial-urinary-sphincter-and-mace-procedure-on-a-pediatric-patient
#7
Paulo Renato Marcelo Moscardi, Natalia Ballesteros, Abd-El-Rahman Abd-El-Barr, Mariarita Salvitti, Miguel Castellan
OBJECTIVE: To describe robotic-assisted laparoscopic artificial urinary sphincter (RAL-AUS) placement and a Malone antegrade continent enema (MACE) procedure on a 6-year-old girl. PATIENTS AND RESULTS: Our patient is a 6-year-old girl with myelomeningocele. She was totally incontinent of urine and chronic constipated despite aggressive bowel regimen. Preoperative workup included renal and bladder ultrasound showing normal findings. Video-urodynamics was also obtained showing low leak point pressure (25 cm H2O) with no reflux...
July 8, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28719972/risk-stratification-of-thyroid-nodules-with-atypia-of-undetermined-significance-follicular-lesion-of-undetermined-significance-aus-flus-cytology-using-ultrasonography-patterns-defined-by-the-2015-ata-guidelines
#8
Ji Hye Lee, Kyunghwa Han, Eun-Kyung Kim, Hee Jung Moon, Jung Hyun Yoon, Vivian Y Park, Jin Young Kwak
PURPOSE: The purpose of this study was to evaluate the predictive value of ultrasonography (US) patterns based on the 2015 American Thyroid Association (ATA) guidelines for malignancy in atypia of undetermined significance or follicular lesion of undetermined significance (AUS/FLUS) nodules. METHODS: From January 2014 to August 2015, 133 thyroid nodules that were initially diagnosed as AUS/FLUS on fine needle aspiration (FNA) were included in this study. Each nodule was assigned a category with US patterns defined by the ATA guidelines...
July 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28714532/thyroid-nodules-classified-as-atypia-or-follicular-lesions-of-undetermined-significance-deserve-further-research-analysis-of-305-surgically-confirmed-nodules
#9
S Turkyilmaz, M Ulusahin, B Celebi, A B Cekic, S Mungan, U Kucuktulu, A Tasdelen, A Guner, A Cinel
OBJECTIVE: The objective of the present study was to determine the malignancy risk for nodules categorised as atypia or follicular lesions of undetermined significance atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) and to investigate the predictors of malignancy. METHODS: All nodules diagnosed as AUS/FLUS on fine needle aspiration (FNAs) performed between January 2011 and December 2015 were retrospectively reviewed...
July 17, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/28709874/analysis-of-hospital-readmissions-after-prosthetic-urologic-surgery-in-the-united-states-nationally-representative-estimates-of-causes-costs-and-predictive-factors
#10
Filippo Pederzoli, Meera R Chappidi, Sarah Collica, Max Kates, Gregory A Joice, Nikolai A Sopko, Francesco Montorsi, Andrea Salonia, Trinity J Bivalacqua
BACKGROUND: The surgical treatment of urinary incontinence and erectile dysfunction by prosthetic devices has become part of urologic practice, although sparse data exist at a national level on readmissions and hospital costs. AIM: To assess causes and costs of early (≤30 days) and late (31-90 days) readmissions after implantation of penile prostheses (PPs), artificial urinary sphincters (AUSs), or PP + AUS. METHODS: Using the 2013 and 2014 US Nationwide Readmission Databases, sociodemographic characteristics, hospital costs, and causes of readmission were compared among PP, AUS and AUS + PP surgeries...
August 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28709851/waves-of-change-national-trends-in-surgical-management-of-male-stress-incontinence
#11
Susan MacDonald, Marc Colaco, Ryan Terlecki
OBJECTIVE: To determine the national trend in surgical management of male stress urinary incontinence (SUI) in the context of the rate of radical prostatectomy (RP) as reported by a national database. Traditionally the artificial urinary sphincter (AUS) has been the gold standard of surgical management, but the male sling represents a newer and popular alternative. Refinements in prostate surgery may reduce the incidence and degree of subsequent SUI. MATERIALS AND METHODS: A retrospective cross sectional analysis was performed using the National Inpatient Survey (NIS) database, which captures discharge data from inpatient and overnight admissions...
July 11, 2017: Urology
https://www.readbyqxmd.com/read/28704697/the-use-of-ultrasound-in-the-clinical-re-staging-of-the-axilla-after-neoadjuvant-chemotherapy-nact
#12
Anastasia Peppe, Robin Wilson, Romney Pope, Kate Downey, Jennifer Rusby
INTRODUCTION: Ultrasound (US) is the imaging modality of choice for staging the axilla prior to surgery in patients with breast cancer (BC). High pathological complete response rates in the axilla after NACT mean a more conservative approach to surgery can be considered. Radiological re-staging is important in this decision making. After the presentation of results from ACOSOG Z1071 in December 2012, formal ultrasound re-assessment of the axilla after primary therapy was specifically requested in our institution...
July 10, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28701893/risk-assessment-of-hepatocellular-carcinoma-in-general-population-by-liver-stiffness-in-combination-with-controlled-attenuation-parameter-using-transient-elastography-a-cross-sectional-study
#13
Takaaki Sugihara, Masahiko Koda, Tomomitsu Matono, Kinya Okamoto, Yoshikazu Murawaki, Hajime Isomoto, Shiho Tokunaga
BACKGROUND: Hepatocellular carcinoma (HCC) in patients without hepatitis B (HBV) and -C virus (HCV) infection are increasing in Japan. Method for detecting high-risk liver diseases of HCC in general population has still not been established. Liver stiffness measurement (LSM) and Controlled Attenuation Parameter (CAP) using transient elastography (TE; FibroScan System) are useful for detecting liver fibrosis and steatosis. The aim of this study is to clarify TE for risk assessment of HCC in general population...
June 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28701827/malignancy-rate-in-thyroid-nodules-categorized-as-atypia-of-undetermined-significance-or-follicular-lesion-of-undetermined-significance-an-institutional-experience
#14
Smita Chandra, Harish Chandra, Sampan S Bisht
INTRODUCTION: Atypia of undetermined significance (AUS) or follicular lesion of undetermined significance (FLUS) of Bethesda system for reporting thyroid cytopathology has emerged as most controversial category due to its heterogeneity and inconsistent usage. Initially associated risk of malignancy was estimated to be about 5-15%, but eventually different results have been obtained across institutions due to variable follow-ups and interpretation. The present study was conducted to evaluate the rate of malignancy along with appropriate management in this category...
July 2017: Journal of Cytology
https://www.readbyqxmd.com/read/28693447/a-cost-effectiveness-analysis-of-midwife-psycho-education-for-fearful-pregnant-women-a-health-system-perspective-for-the-antenatal-period
#15
J Toohill, E Callander, J Gamble, D K Creedy, J Fenwick
BACKGROUND: Psycho-education can reduce childbirth fear and caesarean section numbers. This study determines the cost-effectiveness of a midwife-led psycho-education intervention for women fearful of birth. METHOD: One thousand four hundred ten pregnant women in south-east Queensland, Australia were screened for childbirth fear (W-DEQ A ≥ 66). Women with high scores (n = 339) were randomised to the BELIEF Study (Birth Emotions and Looking to Improve Expectant Fear) to receive psycho-education (n = 170) at 24 and 34 weeks of pregnancy or to the control group (n = 169)...
July 11, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28681033/the-impact-of-incontinence-etiology-on-artificial-urinary-sphincter-outcomes
#16
Adam R Miller, Brian J Linder, Laureano J Rangel, David Y Yang, Daniel S Elliott
PURPOSE: To evaluate the impact of incontinence etiology on artificial urinary sphincter (AUS) device outcomes. MATERIALS AND METHODS: We identified 925 patients who underwent primary AUS placement from 1983 to 2011. The etiology of incontinence was categorized as radical prostatectomy alone, radical prostatectomy with radiation, benign prostate resection, and those with cryotherapy as a salvage prostate cancer treatment. Hazard regression and competing risk analyses were used to determine the association of the etiology of incontinence with device outcomes...
July 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28677189/radiosensibilisierung-durch-braf-inhibitoren
#17
Sophia Boyoung Strobel, Sylvie Pätzold, Lisa Zimmer, Alexandra Jensen, Alexander Enk, Jessica Cecile Hassel
HINTERGRUND: In der letzten Zeit wurden in der Literatur vermehrt erhöhte Hauttoxizitäten während einer Kombinationstherapie mit BRAF Inhibitoren und Radiotherapie beschrieben. MATERIAL UND METHODIK: Wir berichten über sieben Melanompatienten in einem nicht resezierbaren Stadium III oder IV, die eine kombinierte Behandlung aus Bestrahlung und BRAF-Inhibitor erhielten. ERGEBNISSE: Bei allen Patienten konnte durch die Kombinationstherapie ein gutes lokales Ansprechen erreicht werden...
July 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28677176/s1-leitlinie-lip%C3%A3-dem
#18
Stefanie Reich-Schupke, Wilfried Schmeller, Wolfgang Justus Brauer, Manuel E Cornely, Gabriele Faerber, Malte Ludwig, Gerd Lulay, Anya Miller, Stefan Rapprich, Dirk Frank Richter, Vivien Schacht, Klaus Schrader, Markus Stücker, Christian Ure
Die vorliegende überarbeitete Leitlinie zum Lipödem wurde unter der Federführung der Deutschen Gesellschaft für Phlebologie (DGP) erstellt und finanziert. Die Inhalte beruhen auf einer systematischen Literaturrecherche und dem Konsens von acht medizinischen Fachgesellschaften und Berufsverbänden. Die Leitlinie beinhaltet Empfehlungen zu Diagnostik und Therapie des Lipödems. Die Diagnose ist dabei auf der Basis von Anamnese und klinischem Befund zu stellen. Charakteristisch ist eine umschriebene, symmetrisch lokalisierte Vermehrung des Unterhautfettgewebes an den Extremitäten mit deutlicher Disproportion zum Stamm...
July 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28674908/transperineal-reanastomosis-for-treatment-of-highly-recurrent-anastomotic-strictures-after-radical-retropubic-prostatectomy-extended-follow-up
#19
Victor Maximilian Schuettfort, Roland Dahlem, Luis Kluth, Daniel Pfalzgraf, Clemens Rosenbaum, Tim Ludwig, Margit Fisch, Christoph-Philip Reiss
OBJECTIVES: To re-evaluate safety and efficacy of transperineal reanastomosis (TPRA) as a viable therapeutic option in highly recurrent anastomotic strictures (AS) after radical retropubic prostatectomy (RRP). METHODS: Retrospective analysis by standardized questionnaire inquiring for recurrence of stricture, stress urinary incontinence (SUI), sexual function, satisfaction, and changes in quality of life (QoL) was performed in all patients undergoing TPRA. Validated questionnaires (ICIQ-UI, EQ-5D, and IPSS) were included...
July 3, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28673058/targeting-moderate-and-severe-male-stress-urinary-incontinence-with-adjustable-male-slings-and-the-perineal-artificial-urinary-sphincter-focus-on-perioperative-complications-and-device-explantations
#20
Alexander Kretschmer, Tanja Hüsch, Frauke Thomsen, Dominik Kronlachner, Alice Obaje, Ralf Anding, Tobias Pottek, Achim Rose, Roberto Olianas, Alexander Friedl, Wilhelm Hübner, Roland Homberg, Jesco Pfitzenmaier, Fabian Queissert, Carsten M Naumann, Carola Wotzka, Torben Hofmann, Roland Seiler, Axel Haferkamp, Ricarda M Bauer
PURPOSE: To analyze perioperative complications and postoperative explantation rates for selected readjustable male sling systems and the perineal single-cuff artificial urinary sphincter (AUS) in a large, contemporary, multi-institutional patient cohort. METHODS: Two hundred eighty-two male patients who underwent implantation between 2010 and 2012 in 13 participating institutions were included in the study (n=127 adjustable male sling [n=95 Argus classic, n=32 Argus T], n=155 AUS)...
June 2017: International Neurourology Journal
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