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https://www.readbyqxmd.com/read/27911001/diagnostic-accuracy-of-thyroid-imaging-reporting-and-data-system-in-the-prediction-of-malignancy-in-nodules-with-atypia-and-follicular-lesion-of-undetermined-significance-cytologies
#1
Husniye Baser, Bekir Cakir, Oya Topaloglu, Afra Alkan, Sefika Burcak Polat, Hayriye Tatli Dogan, Mustafa Omer Yazicioğlu, Cevdet Aydin, Reyhan Ersoy
OBJECTIVE: Thyroid Imaging Reporting and Data System (TIRADS) is a simple and reliable reporting system for the prediction of malignancy. We aimed to determine the role of TIRADS in the prediction of malignancy in subcategories of Bethesda Category III, atypia of undetermined significance (AUS) and follicular lesion of undetermined significance (FLUS). DESIGN & PATIENTS: A total of 461 nodules with AUS cytology in 450 patients and 179 nodules with FLUS cytology in 168 patients were included...
November 7, 2016: Clinical Endocrinology
https://www.readbyqxmd.com/read/27908376/urethral-strictures-and-artificial-urinary-sphincter-placement
#2
REVIEW
Jeremy B Myers, William O Brant, James N Hotaling, Sara M Lenherr
Patients undergoing artificial urinary sphincter (AUS) placement often have complex medical and surgical histories, such as radical prostatectomy, endoscopic treatment of urethral strictures, previous AUS placement, and prior open urethral surgery. Urethral strictures at the bladder neck, membranous urethra, or site of a previous AUS erosion are problems that profoundly affect the timing and treatment success of AUS placement. Understanding the complexities and outcomes in this subset of patients is the only way to inform shared decision making about treatment of urinary incontinence...
February 2017: Urologic Clinics of North America
https://www.readbyqxmd.com/read/27900467/what-makes-a-smiling-face-look-happy-visual-saliency-distinctiveness-and-affect
#3
Manuel G Calvo, Aida Gutiérrez-García, Mario Del Líbano
We investigated the relative contribution of (a) perceptual (eyes and mouth visual saliency), (b) conceptual or categorical (eye expression distinctiveness), and (c) affective (rated valence and arousal) factors, and (d) specific morphological facial features (Action Units; AUs), to the recognition of facial happiness. The face stimuli conveyed truly happy expressions with a smiling mouth and happy eyes, or blended expressions with a smile but non-happy eyes (neutral, sad, fearful, disgusted, surprised, or angry)...
November 29, 2016: Psychological Research
https://www.readbyqxmd.com/read/27893191/young-investigator-challenge-molecular-testing-in-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features
#4
Xiaoyin Sara Jiang, Grant P Harrison, Michael B Datto
BACKGROUND: Molecular testing provides an important ancillary study for thyroid nodules with indeterminate cytology. The nomenclature shift to "noninvasive follicular thyroid neoplasm with papillary-like nuclear features" (NIFTP) will impact the performance of molecular tests. For the current study, the authors reviewed the performance of the Afirma gene-expression classifier (GEC) and the University of Pittsburgh Medical Center (UPMC) targeted mutation panel tests in thyroid nodules that were subsequently diagnosed as NIFTP on surgical resection...
November 28, 2016: Cancer
https://www.readbyqxmd.com/read/27879101/kompressionstherapie-bei-patienten-mit-ulcus-cruris-venosum
#5
REVIEW
Joachim Dissemond, Bernd Assenheimer, Anke Bültemann, Veronika Gerber, Silvia Gretener, Elisabeth Kohler-von Siebenthal, Sonja Koller, Knut Kröger, Peter Kurz, Severin Läuchli, Christian Münter, Eva-Maria Panfil, Sebastian Probst, Kerstin Protz, Gunnar Riepe, Robert Strohal, Jürg Traber, Hugo Partsch
Wund-D.A.CH. ist der Dachverband deutschsprachiger Fachgesellschaften, die sich mit den Thematiken der Wundbehandlung beschäftigen. Experten verschiedener Fachgesellschaften aus Deutschland, Österreich und der Schweiz haben nun einen aktuellen Konsens der Kompressionstherapie für Patienten mit Ulcus cruris venosum erstellt. In Europa ist das Ulcus cruris venosum eine der häufigsten Ursachen für chronische Wunden. Neben der konservativen und interventionellen Wund- und Venentherapie, ist die Kompressionstherapie die Basis der Behandlungsstrategien...
November 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/27878197/an-anti-ultrasonic-stripping-effect-in-confined-micro-nanoscale-cavities-and-its-applications-for-efficient-multiscale-metallic-patterning
#6
Quan Xiang, Yiqin Chen, Zhiqin Li, Kaixi Bi, Guanhua Zhang, Huigao Duan
We report a method to reliably and efficiently fabricate high-fidelity metallic structures from a ten-nanometer to a millimeter scale based on an anti-ultrasonic-stripping (AUS) effect in confined micro/nanoscale cavities. With this AUS effect, metallic structures, which are surrounded by the pre-patterned closed templates, could be defined through selectively removing the evaporated metallic layer at the top and outside of the templates by ultrasonic-cavitation-induced stripping. Because only pre-patterned templates are required for exposure in this multiscale patterning process, this AUS-based process enables much smaller and more reliable plasmonic nanogaps due to the mitigated proximity effect and allows rapid fabrication of multiscale metallic structures which require both tiny and large structures...
December 1, 2016: Nanoscale
https://www.readbyqxmd.com/read/27872025/contemporary-review-of-artificial-urinary-sphincters-for-male-stress-urinary-incontinence
#7
REVIEW
Faysal A Yafi, Mary K Powers, Jonathan Zurawin, Wayne J G Hellstrom
INTRODUCTION: The most common cause of urinary incontinence in men after radical prostatectomy is intrinsic sphincter deficiency, which can affect long-term quality of life. The prevalence of stress urinary incontinence (SUI) after radical prostatectomy has been reported to be 2.5% to 90%. For patients with moderate to severe male SUI, the artificial urinary sphincter (AUS) is considered the gold standard in surgical treatment. AIM: To review the available literature on the development, patient selection, surgical technique, complications, and management of AUS for male SUI...
April 2016: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/27863771/selection-of-emission-factor-standards-for-estimating-emissions-from-diesel-construction-equipment-in-building-construction-in-the-australian-context
#8
Guomin Zhang, Malindu Sandanayake, Sujeeva Setunge, Chunqing Li, Jun Fang
Emissions from equipment usage and transportation at the construction stage are classified as the direct emissions which include both greenhouse gas (GHG) and non-GHG emissions due to partial combustion of fuel. Unavailability of a reliable and complete inventory restricts an accurate emission evaluation on construction work. The study attempts to review emission factor standards readily available worldwide for estimating emissions from construction equipment. Emission factors published by United States Environmental Protection Agency (US EPA), Australian National Greenhouse Accounts (AUS NGA), Intergovernmental Panel on Climate Change (IPCC) and European Environmental Agency (EEA) are critically reviewed to identify their strengths and weaknesses...
November 15, 2016: Journal of Environmental Management
https://www.readbyqxmd.com/read/27859014/cord-blood-streptococcus-pneumoniae-specific-cellular-immune-responses-predict-early-pneumococcal-carriage-in-high-risk-infants-in-papua-new-guinea
#9
Jacinta P Francis, Peter C Richmond, Deborah Strickland, Susan L Prescott, William S Pomat, Audrey Michael, Marie A Nadal-Sims, Catherine J Edwards-Devitt, Patrick G Holt, Deborah Lehmann, Anita H J van den Biggelaar
Background In areas where Streptococcus pneumoniae is highly endemic, infants experience very early pneumococcal colonization of the upper respiratory tract with carriage often persisting into adulthood. We aimed to explore whether newborns in high risk areas have pre-existing pneumococcal-specific cellular immune responses that may affect early pneumococcal acquisition. Methods Cord blood mononuclear cells (CBMC) of 84 Papua New Guinean (PNG; high endemic) and 33 Australian (AUS; low endemic) newborns were stimulated in vitro with detoxified pneumolysin (dPly) or pneumococcal surface protein A (PspA; families 1 and 2) and compared for cytokine responses...
November 18, 2016: Clinical and Experimental Immunology
https://www.readbyqxmd.com/read/27855679/a-pilot-study-of-toceranib-vinblastine-therapy-for-canine-transitional-cell-carcinoma
#10
Sarah B Rippy, Heather L Gardner, Sandra M Nguyen, Emma E Warry, Roberta A Portela, William Tod Drost, Eric T Hostnik, Eric M Green, Dennis J Chew, Juan Peng, Cheryl A London
BACKGROUND: Effective therapies for transitional cell carcinoma (TCC) are limited, with objective response rates to most chemotherapeutic regimens below 20%. The purpose of this study was to investigate the biologic activity of combined toceranib phosphate and vinblastine chemotherapy for treatment of TCC. A secondary objective was to compare the utility of Computed Tomography (CT) and abdominal ultrasound (AUS) in tumor response assessments. RESULTS: Dogs with TCC received vinblastine at 1...
November 17, 2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27853175/salinity-tolerance-loci-revealed-in-rice-using-high-throughput-non-invasive-phenotyping
#11
Nadia Al-Tamimi, Chris Brien, Helena Oakey, Bettina Berger, Stephanie Saade, Yung Shwen Ho, Sandra M Schmöckel, Mark Tester, Sónia Negrão
High-throughput phenotyping produces multiple measurements over time, which require new methods of analyses that are flexible in their quantification of plant growth and transpiration, yet are computationally economic. Here we develop such analyses and apply this to a rice population genotyped with a 700k SNP high-density array. Two rice diversity panels, indica and aus, containing a total of 553 genotypes, are phenotyped in waterlogged conditions. Using cubic smoothing splines to estimate plant growth and transpiration, we identify four time intervals that characterize the early responses of rice to salinity...
November 17, 2016: Nature Communications
https://www.readbyqxmd.com/read/27852075/thyroid-atypia-follicular-lesion-of-undetermined-significance-attitudes-towards-the-diagnosis-of-bethesda-system-iii-nodules
#12
Lourdes Estrada Muñoz, Cristina Díaz Del Arco, Luis Ortega Medina, M Jesús Fernández Aceñero
OBJECTIVES: To review our institutional experience and to analyze the clinical decisions made after a cytological diagnosis of atypia of undetermined significance or follicular lesion of undetermined significance (AUS/FLUS). STUDY DESIGN: This is a retrospective review of all thyroid fine-needle aspiration (FNA) cytologies performed in the Hospital Clínico San Carlos (Madrid) between 2010 and 2014. RESULTS: One hundred thirty thyroid FNA were categorized as AUS/FLUS (5%)...
November 17, 2016: Acta Cytologica
https://www.readbyqxmd.com/read/27852041/accuracy-of-axillary-ultrasound-after-different-neoadjuvant-chemotherapy-cycles-in-breast-cancer-patients
#13
Bei-Bei Ye, Hong-Meng Zhao, Yue Yu, Jie Ge, Xin Wang, Xu-Chen Cao
BACKGROUND: This study determined whether axillary ultrasound (AUS) accurately predicted the status of axillary lymph nodes of patients who received different number of cycles of neoadjuvant chemotherapy (NAC). MATERIALS AND METHODS: From 2008 to 2015, 656 cases of patients with breast cancers who received NAC and had subsequent axillary lymph node dissection were included in this study. The findings of preoperative AUS were tested by pathological examination. We evaluated the sensitivity, specificity and accuracy of AUS for patients who received two-, four-, and six-cycle NAC...
November 11, 2016: Oncotarget
https://www.readbyqxmd.com/read/27848161/genome-wide-association-mapping-of-cold-tolerance-genes-at-the-seedling-stage-in-rice
#14
Dan Wang, Jinling Liu, Chengang Li, Houxiang Kang, Yue Wang, Xinqiu Tan, Minghao Liu, Yufei Deng, Zhilong Wang, Yong Liu, Deyong Zhang, Yinghui Xiao, Guo-Liang Wang
BACKGROUND: Rice is a temperature-sensitive crop and its production is severely affected by low temperature in temperate and sub-tropical regions. To understand the genetic basis of cold tolerance in rice, we evaluated the cold tolerance at the seedling stage (CTS) of 295 rice cultivars in the rice diversity panel 1 (RDP1), these cultivars were collected from 82 countries. RESULTS: The evaluations revealed that both temperate and tropical japonica rice cultivars are more tolerant to cold stress than indica and AUS cultivars...
December 2016: Rice
https://www.readbyqxmd.com/read/27834083/molecular-diagnosis-using-residual-liquid-based-cytology-materials-for-patients-with-nondiagnostic-or-indeterminate-thyroid-nodules
#15
Hyemi Kwon, Won Gu Kim, Markus Eszlinger, Ralf Paschke, Dong Eun Song, Mijin Kim, Suyeon Park, Min Ji Jeon, Tae Yong Kim, Young Kee Shong, Won Bae Kim
BACKGROUND: Molecular analysis for common somatic mutations in thyroid cancer can improve diagnostic accuracy of fine-needle aspiration cytology (FNAC) in the nondiagnostic or indeterminate category of thyroid nodules. In this study, we evaluated the feasibility of molecular diagnosis from residual liquid-based cytology (LBC) material after cytological diagnosis. METHODS: This prospective study enrolled 53 patients with thyroid nodules diagnosed as nondiagnostic, atypia of undetermined significance (AUS), or follicular lesion of undetermined significance (FLUS) after FNAC...
November 4, 2016: Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27833617/an-efficient-strategy-combining-ssr-markers-and-advanced-qtl-seq-driven-qtl-mapping-unravels-candidate-genes-regulating-grain-weight-in-rice
#16
Anurag Daware, Sweta Das, Rishi Srivastava, Saurabh Badoni, Ashok K Singh, Pinky Agarwal, Swarup K Parida, Akhilesh K Tyagi
Development and use of genome-wide informative simple sequence repeat (SSR) markers and novel integrated genomic strategies are vital to drive genomics-assisted breeding applications and for efficient dissection of quantitative trait loci (QTLs) underlying complex traits in rice. The present study developed 6244 genome-wide informative SSR markers exhibiting in silico fragment length polymorphism based on repeat-unit variations among genomic sequences of 11 indica, japonica, aus, and wild rice accessions. These markers were mapped on diverse coding and non-coding sequence components of known cloned/candidate genes annotated from 12 chromosomes and revealed a much higher amplification (97%) and polymorphic potential (88%) along with wider genetic/functional diversity level (16-74% with a mean 53%) especially among accessions belonging to indica cultivar group, suggesting their utility in large-scale genomics-assisted breeding applications in rice...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27819751/artificial-urinary-sphincter-for-urinary-incontinence-after-radical-prostatectomy-a-historical-cohort-from-2004-to-2015
#17
Augusto Cesar Soares Dos Santos, Luíza de Oliveira Rodrigues, Daniela Castelo Azevedo, Lélia Maria de Almeida Carvalho, Mariana Ribeiro Fernandes, Sandra de Oliveira Sapori Avelar, Maria Glória Cruvinel Horta, Silvana Márcia Bruschi Kelles
This study aimed to retrospectively evaluate a cohort of patients with prostate cancer and persistent urinary incontinence after radical prostatectomy. From January 2004 to December 2015, eighty-six individuals were identified to have received an AUS im¬plant, provided by a private nonprofit HMO operating in Belo Horizonte, Brazil. On total, there were 91 AUS implants, with a median interval between radical prostatectomy and AUS implant of 3.6 years (IQR 1.9 to 5.5). The rate of AUS cumulative survival, after a median follow-up of 4...
November 2, 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27797881/persistent-urinary-incontinence-after-a-robot-assisted-artificial-urinary-sphincter-procedure-lessons-learnt-from-two-cases
#18
François Hervé, Nicolaas Lumen, An-Sofie Goessaert, Karel Everaert
This case report describes 2 cases of persistent urinary incontinence in the beginning of the learning curve of robot-assisted bladder neck implantation of an artificial urinary sphincter (RA-AUS) in men at risk for erosion due to neurological lesions. Among a series of 4 RA-AUS, 2 patients still experienced urinary incontinence after surgery. A complete urological workup was strictly normal and did not show any device malfunction. However, during an AUS revision in these two patients, exploration revealed that the cuff was not tight enough...
October 25, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27785433/the-impact-of-androgen-deprivation-on-artificial-urinary-sphincter-outcomes
#19
George C Bailey, Brian J Linder, Marcelino E Rivera, Matthew J Ziegelmann, Laureano J Rangel, Daniel S Elliott
BACKGROUND: Androgen deprivation therapy (ADT) causes systemic tissue atrophy. It is unclear if this tissue atrophy adversely impacts artificial urinary sphincter (AUS) outcomes. We sought to evaluate the effect of ADT on adverse AUS outcomes. METHODS: We retrospectively identified 518 men undergoing primary AUS placement at our institution between 1998 and 2014. Rates of device explant for infection/erosion, mechanical failure, and urethral atrophy in men with >6 months of ADT use within 2 years prior to AUS placement were compared to ADT naive men...
October 2016: Translational Andrology and Urology
https://www.readbyqxmd.com/read/27774696/utility-of-computed-tomography-versus-abdominal-ultrasound-examination-to-identify-iliosacral-lymphadenomegaly-in-dogs-with-apocrine-gland-adenocarcinoma-of-the-anal-sac
#20
S Palladino, M A Keyerleber, R G King, K E Burgess
BACKGROUND: Apocrine gland adenocarcinoma of the anal sac (AGAAS) is associated with high rates of iliosacral lymph node metastasis, which may influence treatment and prognosis. Magnetic resonance imaging (MRI) recently has been shown to be more sensitive than abdominal ultrasound examination (AUS) in affected patients. OBJECTIVE: To compare the rate of detection of iliosacral lymphadenomegaly between AUS and computed tomography (CT) in dogs with AGAAS. ANIMALS: Cohort A: A total of 30 presumed normal dogs...
November 2016: Journal of Veterinary Internal Medicine
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