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https://www.readbyqxmd.com/read/28914983/suggesting-the-cytologic-diagnosis-of-noninvasive-follicular-thyroid-neoplasm-with-papillary-like-nuclear-features-niftp-a-retrospective-analysis-of-atypical-and-suspicious-nodules
#1
Kyle C Strickland, Brooke E Howitt, Justine A Barletta, Edmund S Cibas, Jeffrey F Krane
BACKGROUND: The term "noninvasive follicular thyroid neoplasm with papillary-like nuclear features" (NIFTP) has replaced a subset of follicular variant of papillary thyroid carcinoma due to the indolent behavior of such tumors. NIFTPs are most often classified in an "indeterminate" diagnostic category. In the current study, the authors sought to identify cytologic features helpful in distinguishing NIFTP from other entities in these categories, particularly benign nodules. METHODS: The authors retrospectively evaluated a consecutive cohort of 130 thyroid fine-needle aspiration (FNA) specimens with an indeterminate diagnosis and available histopathologic follow-up...
September 15, 2017: Cancer
https://www.readbyqxmd.com/read/28906423/empowering-parents-of-australian-infants-and-children-in-hospital-translation-cultural-adaptation-and-validation-of-the-empowerment-of-parents-in-the-intensive-care-30-aus-questionnaire
#2
Fenella J Gill, Sally Wilson, Laurene Aydon, Gavin D Leslie, Jos M Latour
OBJECTIVES: To translate, culturally adapt, and psychometrically test the EMpowerment of PArents in The Intensive Care-30 questionnaire in Australian pediatric critical care, neonatal, and pediatric ward settings. DESIGN: Cross-sectional, descriptive, multicenter study conducted in two phases; 1) translation and cultural adaptation and 2) validation of the EMpowerment of PArents in The Intensive Care-30 questionnaire. SETTINGS: Two Western Australian sites, the PICU and two pediatric wards of a children's hospital and the neonatal unit of a women's and newborn hospital...
September 12, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28904901/artificial-urinary-sphincter
#3
REVIEW
William O Brant, Francisco E Martins
Although currently still the gold standard treatment for post-prostatectomy urinary incontinence, the artificial urinary sphincter (AUS) (AMS800) is an invasive procedure with associated risks factors. In this paper, we aim to outline what the scientific literature and what we personally believe are the factors that are useful and/or necessary to mitigate these risks, including both patient factors and surgeon factors. We also review special populations, including transcorporal (TC) AUS approach, AUS with inflatable penile prosthesis, AUS after male urethral sling, AUS erosion management, and AUS after orthotopic urinary diversion...
August 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28904899/virtue-quadratic-male-sling-for-stress-incontinence-surgical-guide-for-placement-and-delayed-revision
#4
REVIEW
Rachel S Rubin, Keith R Xavier, Eugene Rhee
The algorithm for surgical management of post prostatectomy incontinence classically includes male slings and artificial urinary sphincter (AUS) placement. The Virtue Quadratic Male Sling was designed to provide both urethral elevation and prepubic compression making it a viable option for a wider spectrum of incontinent men whose symptoms range from mild to severe. With a focus on two key steps of the surgery, (I) sling fixation (II) use of intraoperative retrograde leak point pressure (RLPP), this guide is intended to outline a safe and efficacious treatment for post-prostatectomy incontinence...
August 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28877948/appropriateness-of-percutaneous-coronary-interventions-in-patients-with-ischaemic-heart-disease-in-italy-the-apache-pilot-study
#5
Sergio Leonardi, Marcello Marino, Gabriele Crimi, Florinda Maiorana, Diego Rizzotti, Corrado Lettieri, Luca Bettari, Marco Zuccari, Paolo Sganzerla, Simone Tresoldi, Marianna Adamo, Sergio Ghiringhelli, Carlo Sponzilli, Giampaolo Pasquetto, Andrea Pavei, Luigi Pedon, Luciano Bassan, Mario Bollati, Paola Camisasca, Daniela Trabattoni, Marta Brancati, Arnaldo Poli, Claudio Panciroli, Maddalena Lettino, Giuseppe Tarelli, Giuseppe Tarantini, Leonardo De Luca, Ferdinando Varbella, Giuseppe Musumeci, Stefano De Servi
OBJECTIVES: To first explore in Italy appropriateness of indication, adherence to guideline recommendations and mode of selection for coronary revascularisation. DESIGN: Retrospective, pilot study. SETTING: 22 percutaneous coronary intervention (PCI)-performing hospitals (20 patients per site), 13 (59%) with on-site cardiac surgery. PARTICIPANTS: 440 patients who received PCI for stable coronary artery disease (CAD) or non-ST elevation acute coronary syndrome were independently selected in a 4:1 ratio with half diabetics...
September 5, 2017: BMJ Open
https://www.readbyqxmd.com/read/28877096/clinical-parameter-for-deciding-the-brafv600e-mutation-test-in-atypia-of-undetermined-significance-follicular-lesion-of-undetermined-significance-thyroid-nodules-us-features-according-to-tirads
#6
Miribi Rho, Eun-Kyung Kim, Hee Jung Moon, Jung Hyun Yoon, Vivian Y Park, Kyunghwa Han, Jin Young Kwak
This study aimed to investigate the usefulness of a thyroid imaging reporting and data system (TIRADS) to select thyroid nodules with atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) cytology for additional BRAF mutation testing. Three hundred three thyroid nodules were included. Statistical analysis was performed at both patient and nodule levels according to BRAF mutation positivity and clinical factors. Univariate and multivariate logistic regression analyses were performed to assess independent associations between BRAF mutation positivity and clinical factors...
September 4, 2017: Ultrasound Quarterly
https://www.readbyqxmd.com/read/28872247/update-zum-klinischen-einsatz-von-inhibitoren-mutierter-phosphokinasen-beim-melanom
#7
REVIEW
Ioana Cosgarea, Cathrin Ritter, Jürgen C Becker, Dirk Schadendorf, Selma Ugurel
Die Behandlungsstrategie beim metastasierten Melanom hat sich mit der Identifizierung therapeutisch angreifbarer molekularer Zielstrukturen innerhalb zellulärer Signalwege radikal geändert. Durch die Zulassung von Substanzen, die gezielt an den zentralen Schaltmolekülen, den Phosphokinasen, angreifen, können diese Signalwege selektiv abgeschaltet werden. Dies ist insbesondere bei denjenigen Tumoren von Interesse, deren Signalwege durch aktivierende Mutationen der für die Schaltmoleküle kodierenden Gene konstitutiv aktiviert sind...
September 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28872230/deutsches-nationales-krebshilfe-monitoring-2015-2019-studienprotokoll-und-erste-ergebnisse
#8
Sven Schneider, Tatiana Görig, Laura Schilling, Eckhard W Breitbart, Rüdiger Greinert, Katharina Diehl
HINTERGRUND UND ZIELE: Das Projekt "Nationales Krebshilfe-Monitoring zur Solariennutzung" (National Cancer Aid Monitoring of Tanning Bed Use, NCAM) ist eine deutsche Großstudie mit dem Ziel, die wichtigsten Risikofaktoren für Hautkrebs zu beobachten: natürliches Sonnenlicht und künstliche UV-Strahlung. TEILNEHMER UND METHODEN: NCAM ist eine bundesweite Querschnittstudie mit zunächst vier Runden der Datenerfassung (sogenannten Wellen) zwischen 2015 und 2018...
September 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28862810/a-follow-up-study-on-thyroid-aspirates-reported-as-atypia-of-undetermined-significance-follicular-lesion-of-undetermined-significance-and-follicular-neoplasm-suspicious-for-follicular-neoplasm-a-multicenter-study-from-the-arabian-gulf-region
#9
Mousa A Al-Abbadi, Sameera Q Shareef, Mohammad M Yousef, Nidal M Almasri, Huda E Mustafa, Hameed Aljawad, Jassim A Ali, Alan Groves, Yasmen Alsaihati
OBJECTIVE: This is a multicenter study which was conducted to evaluate the follow-up on thyroid aspirate cases with atypia of undetermined significance/follicular cells of undetermined significance (AUS/FLUS) and follicular neoplasm or suspicious for follicular neoplasm (FN/SFN) using the Bethesda system for reporting thyroid cytology (TBSRTC). MATERIALS AND METHODS: The archival materials of all thyroid fine-needle aspirates over a 5-year period were retrieved from 3 institutions in the Arabian Gulf Region...
September 1, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28830316/test-retest-reliability-and-internal-consistency-of-the-activity-card-sort-australia-18-64
#10
Louise Gustafsson, Inez Hui Min Hung, Jacki Liddle
The Activity Card Sort (ACS) measures activity engagement levels. The Activity Card Sort-Australian version for adults aged 18 to 64 (ACS-Aus (18-64)) was recently developed, and psychometric properties have not yet been determined. This study was established to determine the test-retest reliability and internal consistency of the ACS-Aus (18-64) and describe activity engagement trends for healthy adults. Fifty-four adults aged 18 to 64 participated in this descriptive study. The ACS-Aus (18-64) demonstrated excellent test-retest reliability ( r = ...
January 2017: OTJR: Occupation, Participation and Health
https://www.readbyqxmd.com/read/28794592/radiotherapy-is-associated-with-reduced-continence-outcomes-following-implantation-of-the-artificial-urinary-sphincter-in-men-with-post-radical-prostatectomy-incontinence
#11
Stephanie Guillaumier, Eskinder Solomon, Julie Jenks, Mahreen Pakzad, Rizwan Hamid, Jeremy Ockrim, Julian Shah, Tamsin Greenwell
OBJECTIVES: The objective of this study is to present the outcomes of men undergoing implantation of artificial urinary sphincter, after treatment for prostate cancer and also to determine the effect of radiotherapy on continence outcomes after artificial urinary sphincter (AUS) implantation. MATERIALS AND METHODS: A prospectively acquired database of all 184 patients having AUS insertion between 2002 and 2012 was reviewed, and demographic data, mode of prostate cancer treatment(s) before implantation, and outcome in terms of complete continence (pad free, leak free) were assessed...
July 2017: Urology Annals
https://www.readbyqxmd.com/read/28791230/contemporary-surgical-devices-for-male-stress-urinary-incontinence-a-review-of-technological-advances-in-current-continence-surgery
#12
REVIEW
Eric Chung
Male stress urinary incontinence (SUI) remains a debilitating condition that adversely impacts all domains of quality of life and is associated with significant social stigma and health economic burden. The incidence of post-prostatectomy urinary incontinence (PPI) depends on the definition of urinary incontinence and the length of patient follow up. In patients with persistent PPI following failure of conservative measures, surgical treatment is recommended although there is no published guideline on when surgery should be performed, and what the best surgical option is...
July 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28791228/management-of-bladder-neck-stenosis-and-urethral-stricture-and-stenosis-following-treatment-for-prostate-cancer
#13
REVIEW
Helen L Nicholson, Yasser Al-Hakeem, Javier J Maldonado, Vincent Tse
The aim of this review is to examine all urethral strictures and stenoses subsequent to treatment for prostate cancer, including radical prostatectomy (RP), radiotherapy, high intensity focused ultrasound (HIFU) and cryotherapy. The overall majority respond to endoscopic treatment, including dilatation, direct visual internal urethrotomy (DVIU) or bladder neck incision (BNI). There are adjunct treatments to endoscopic management, including injections of corticosteroids and mitomycin C (MMC) and urethral stents, which remain controversial and are not currently mainstay of treatment...
July 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28789963/graphene-oxide-layer-decorated-gold-nanoparticles-based-immunosensor-for-the-detection-of-prostate-cancer-risk-factor
#14
Mintu Pal, Raju Khan
In this work, we report a novel electrochemical immunosensor based on gold nanoparticles deposited on the surface of graphene oxide layers and was used for immobilization of monoclonal anti-PSA antibody via EDC/NHS coupling method to detect prostate-specific antigen (PSA), a valuable biomarker for early detection of prostate cancer. To confirm the functionality of the antibody, we performed immunofluorescence staining using human prostate adenocarcinoma cells, LNCaP. Scanning Electron Microscopy (SEM), cyclic voltammetry, and other electrochemical techniques were used to characterize the resulting electrode surface...
August 5, 2017: Analytical Biochemistry
https://www.readbyqxmd.com/read/28783634/nonnegative-decompositions-for-dynamic-visual-data-analysis
#15
Lazaros Zafeiriou, Yannis Panagakis, Maja Pantic, Stefanos Zafeiriou
The analysis of high-dimensional, possibly temporally misaligned, time-varying visual data is a fundamental task in disciplines such as image, vision, and behaviour computing. In this paper, we focus on dynamic facial behaviour analysis and in particular on the analysis of facial expressions. Distinct from the previous approaches, where sets of facial landmarks are used for face representation, raw pixel intensities are exploited for 1) unsupervised analysis of the temporal phases of facial expressions and facial action unitis (AUs) and 2) temporal alignment of a certain facial behaviour displayed by two different persons...
August 2, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28760684/bericht-aus-der-praxis-practice-report-how-to-successfully-establish-pal-in-medical-education-10-tips-to-succeed-in-pal-based-courses-in-undergraduate-medical-education-ugme
#16
Matthias Hofer, Kathrin Klein, Bastian Malzkorn, Alice Martin, Christian Weigel, Ole Martin
This article aims to provide useful suggestions for the implementation of new courses with peer-assisted learning (PAL) in undergraduate medical education (UGME). It presents 10 key tips for needs assessment, clarification of goals and objectives for internal marketing, the choice of teaching formats, fund raising, recruiting of educators, qualification of peer tutors, the fun factor, how to establish a structured and longitudinal curriculum, assessment methods and motivation, collecting feedback and the use of its results...
August 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28743562/robotic-assisted-laparoscopic-artificial-urinary-sphincter-and-mace-procedure-on-a-pediatric-patient
#17
Paulo Renato Marcelo Moscardi, Natalia Ballesteros, Abd-El-Rahman Abd-El-Barr, Mariarita Salvitti, Miguel Castellan
OBJECTIVE: To describe robotic-assisted laparoscopic artificial urinary sphincter (RAL-AUS) placement and a Malone antegrade continent enema (MACE) procedure on a 6-year-old girl. PATIENTS AND RESULTS: Our patient is a 6-year-old girl with myelomeningocele. She was totally incontinent of urine and chronic constipated despite aggressive bowel regimen. Preoperative workup included renal and bladder ultrasound showing normal findings. Video-urodynamics was also obtained showing low leak point pressure (25 cm H2O) with no reflux...
July 8, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28719972/risk-stratification-of-thyroid-nodules-with-atypia-of-undetermined-significance-follicular-lesion-of-undetermined-significance-aus-flus-cytology-using-ultrasonography-patterns-defined-by-the-2015-ata-guidelines
#18
Ji Hye Lee, Kyunghwa Han, Eun-Kyung Kim, Hee Jung Moon, Jung Hyun Yoon, Vivian Y Park, Jin Young Kwak
PURPOSE: The purpose of this study was to evaluate the predictive value of ultrasonography (US) patterns based on the 2015 American Thyroid Association (ATA) guidelines for malignancy in atypia of undetermined significance or follicular lesion of undetermined significance (AUS/FLUS) nodules. METHODS: From January 2014 to August 2015, 133 thyroid nodules that were initially diagnosed as AUS/FLUS on fine needle aspiration (FNA) were included in this study. Each nodule was assigned a category with US patterns defined by the ATA guidelines...
September 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28714532/thyroid-nodules-classified-as-atypia-or-follicular-lesions-of-undetermined-significance-deserve-further-research-analysis-of-305-surgically-confirmed-nodules
#19
S Turkyilmaz, M Ulusahin, B Celebi, A B Cekic, S Mungan, U Kucuktulu, A Tasdelen, A Guner, A Cinel
OBJECTIVE: The objective of the present study was to determine the malignancy risk for nodules categorised as atypia or follicular lesions of undetermined significance atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) and to investigate the predictors of malignancy. METHODS: All nodules diagnosed as AUS/FLUS on fine needle aspiration (FNAs) performed between January 2011 and December 2015 were retrospectively reviewed...
October 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/28709874/analysis-of-hospital-readmissions-after-prosthetic-urologic-surgery-in-the-united-states-nationally-representative-estimates-of-causes-costs-and-predictive-factors
#20
Filippo Pederzoli, Meera R Chappidi, Sarah Collica, Max Kates, Gregory A Joice, Nikolai A Sopko, Francesco Montorsi, Andrea Salonia, Trinity J Bivalacqua
BACKGROUND: The surgical treatment of urinary incontinence and erectile dysfunction by prosthetic devices has become part of urologic practice, although sparse data exist at a national level on readmissions and hospital costs. AIM: To assess causes and costs of early (≤30 days) and late (31-90 days) readmissions after implantation of penile prostheses (PPs), artificial urinary sphincters (AUSs), or PP + AUS. METHODS: Using the 2013 and 2014 US Nationwide Readmission Databases, sociodemographic characteristics, hospital costs, and causes of readmission were compared among PP, AUS and AUS + PP surgeries...
August 2017: Journal of Sexual Medicine
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