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https://www.readbyqxmd.com/read/28771832/spectracam-%C3%A2-a-new-polarized-hyperspectral-imaging-system-for-repeatable-and-reproducible-in-vivo-skin-quantification-of-melanin-total-hemoglobin-and-oxygen-saturation
#1
A Nkengne, J Robic, P Seroul, S Gueheunneux, M Jomier, K Vie
BACKGROUND: An accurate way to determine skin pigmentation is to acquire the spectral reflectance of a skin sample and to quantify chromophores by reverse calculation from physical models of light propagation. Therefore, we tested a new hyperspectral imaging device and software suite, the SpectraCam(®) system, and evaluated its accuracy to quantify skin chromophores. METHODS: Validation of the SpectraCam(®) system was performed by, firstly, comparing the known and the acquired reflectance spectra of color phantoms...
August 2, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28689323/a-sensitive-colorimetric-assay-system-for-nucleic-acid-detection-based-on-isothermal-signal-amplification-technology
#2
Bo Hu, Jing Guo, Ying Xu, Hua Wei, Guojie Zhao, Yifu Guan
Rapid and accurate detection of microRNAs in biological systems is of great importance. Here, we report the development of a visual colorimetric assay which possesses the high amplification capabilities and high selectivity of the rolling circle amplification (RCA) method and the simplicity and convenience of gold nanoparticles used as a signal indicator. The designed padlock probe recognizes the target miRNA and is circularized, and then acts as the template to extend the target miRNA into a long single-stranded nucleotide chain of many tandem repeats of nucleotide sequences...
July 8, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28622082/comparing-the-effectiveness-of-fractional-co2-laser-and-the-combination-therapy-with-micro-needling-and-topical-10-trichloroacetic-acid-to-remove-infra-orbital-dark-circles-in-tehran-women
#3
Abbas Zamanian, Mahba Azizi, Mohamadreza Ghasemi, Elham Behrangi, Sedigheh Naeji
BACKGROUND: Infra-orbital dark circles in now identified as a cosmetic problem which should be considered in treatment issue. The present study aimed to assess and compare the clinical efficiency of the combination of micro-needling and 10% trichloroacetic acid (TCA) cream as well as carbon dioxide laser in the management of infra-orbital dark circles. METHODS: This randomized clinical trial was performed on women ranged 28 to 62 years that complained of infra-orbital dark circles...
June 16, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28501377/structural-changes-associated-with-delayed-dark-adaptation-in-age-related-macular-degeneration
#4
Inês Laíns, John B Miller, Dong H Park, Edem Tsikata, Samaneh Davoudi, Safa Rahmani, Jonathan Pierce, Rufino Silva, Teresa C Chen, Ivana K Kim, Demetrios Vavvas, Joan W Miller, Deeba Husain
PURPOSE: To examine the relationship between dark adaptation (DA) and optical coherence tomography (OCT)-based macular morphology in age-related macular degeneration (AMD). DESIGN: Prospective, cross-sectional study. PARTICIPANTS: Patients with AMD and a comparison group (>50 years) without any vitreoretinal disease. METHODS: All participants were imaged with spectral-domain OCT and color fundus photographs, and then staged for AMD (Age-related Eye Disease Study system)...
May 10, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28385012/eosinophilic-encephalomyelitis-in-horses-caused-by-protostrongylid-parasites
#5
Eun-Jung Bak, Young-Hwa Jean, Gye-Hyeong Woo
Four thoroughbred horses showing lameness, ataxia, circling, depression, recumbency, and seizures, were submitted. The horses had grossly weak to dark red appearances and foci in the central nervous system. Multifocal to coalescing eosinophilic necrotizing encephalomyelitis was observed histologically in the CNS as well as intact or degenerated nematodes. Nematodes had polymyarian-coelomyarian musculature, a smooth thin cuticle, and intestines lined by multinucleated cells with microvilli. These traits suggested the nematodes belonged to the family Protostrongylidae, which includes P...
April 6, 2017: Journal of Veterinary Science
https://www.readbyqxmd.com/read/28095138/leber-congenital-amaurosis-from-darkness-to-light-an-ode-to-irene-maumenee
#6
Razek Georges Coussa, Irma Lopez Solache, Robert K Koenekoop
This article is dedicated to Irene Hussels Maumenee, Professor of Human Genetics and Ophthalmology, Johns Hopkins' Wilmer Eye Institute, Ocular Genetics Fellowship director in 1994-1995. Leber congenital amaurosis (LCA) has almost come full circle, from a profound and molecularly uncharacterized form of congenital retinal blindness to one in which a large number of causative genes and disease pathways are known, and the world's first human retinal disease to be treated by gene therapy. Dr. Maumenee's insights, efforts, and leadership have contributed significantly to this remarkable scientific journey...
January 2017: Ophthalmic Genetics
https://www.readbyqxmd.com/read/28047321/tu-ab-bra-04-an-investigation-of-metal-artifact-effects-in-multi-modalities-development-of-mri-ct-heterogeneous-head-and-neck-phantom-for-mri-ct-registration
#7
M Lee, K Song, B Choe, T Suh
PURPOSE: The purpose of this investigation was to develop an CT-MR head and neck phantom which can investigate dose calculation differences between density-assigned MRI and CT, and to compare non-implant inserted registered MR-CT registered image with artifact reduced image of MR-CT registered image. It is to identify potential limitations related to dental implants of MR image and CT image and maximize the advantages to find interactive method to use registered image. METHODS: The phantom comprises half-circled shape which shaped to simulated the anatomical structures of a human head and neck...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27799805/clinical-effects-of-an-oral-supplement-rich-in-antioxidants-on-skin-radiance-in-women
#8
Marion Dumoulin, David Gaudout, Benoit Lemaire
BACKGROUND: Environmental factors impact the skin aging resulting in decrease of skin radiance. Nutrition and particularly antioxidants could help to fight against skin degradation. OBJECTIVE: The aim of this study was to evaluate the effects of an oral supplement rich in specific antioxidants, SkinAx(2TM), on the improvement of the skin radiance in women. METHODS: The open-label clinical study enrolled 35 women, aged 40-70, with facial dull complexion...
2016: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/27721911/periorbital-hyperpigmentation-in-patients-with-xanthelasma-palpebrarum-an-interesting-observation
#9
Eftychia Platsidaki, Anargyros Kouris, Efthymia Agiasofitou, Christina Antoniou, Georgios Kontochristopoulos
Background: Xanthelasma palpebrarum refers to xanthomas that occur more often near the inner canthus of the eyelid. Periorbital hyperpigmentation presents as a dark area surrounding the eyelids. Objective: In the present study, the authors examined the prevalence and the associated factors of periorbital hyperpigmentation among patients with xanthelasma. Methods: One hundred and fourteen patients with xanthelasma palpebrarum were examined for the presence of dark circles. Detailed questionnaires regarding the history of diabetes, hypothyroidism, smoking status, and weight were completed by all patients...
April 2016: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/27688436/skin-hyperpigmentation-in-indian-population-insights-and-best-practice
#10
Stephanie Nouveau, Divya Agrawal, Malavika Kohli, Francoise Bernerd, Namita Misra, Chitra Shivanand Nayak
Skin pigmentation is one of the most strikingly variable phenotypes in humans, therefore making cutaneous pigmentation disorders frequent symptoms manifesting in a multitude of forms. The most common among them include lentigines, postinflammatory hyperpigmentation, dark eye circles, and melasma. Variability of skin tones throughout the world is well-documented, some skin tones being reported as more susceptible to pigmentation disorders than others, especially in Asia and India. Furthermore, exposure to ultraviolet radiation is known to trigger or exacerbate pigmentation disorders...
September 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27631664/modeling-the-test-retest-statistics-of-a-localization-experiment-in-the-full-horizontal-plane
#11
André Morsnowski, Steffen Maune
HYPOTHESIS: Two approaches to model the test-retest statistics of a localization experiment basing on Gaussian distribution and on surrogate data are introduced. Their efficiency is investigated using different measures describing directional hearing ability. BACKGROUND: A localization experiment in the full horizontal plane is a challenging task for hearing impaired patients. In clinical routine, we use this experiment to evaluate the progress of our cochlear implant (CI) recipients...
October 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27605999/crown-of-thorns-starfish-have-true-image-forming-vision
#12
Ronald Petie, Anders Garm, Michael R Hall
BACKGROUND: Photoreceptors have evolved numerous times giving organisms the ability to detect light and respond to specific visual stimuli. Studies into the visual abilities of the Asteroidea (Echinodermata) have recently shown that species within this class have a more developed visual sense than previously thought and it has been demonstrated that starfish use visual information for orientation within their habitat. Whereas image forming eyes have been suggested for starfish, direct experimental proof of true spatial vision has not yet been obtained...
2016: Frontiers in Zoology
https://www.readbyqxmd.com/read/27522505/treatment-of-infraorbital-dark-circles-using-694-nm-fractional-q-switched-ruby-laser
#13
Tian-Hua Xu, Yuan-Hong Li, John Z S Chen, Xing-Hua Gao, Hong-Duo Chen
The objective of this study was to evaluate the efficacy and safety of using a 694-nm fractional Q-switched ruby laser to treat infraorbital dark circles. Thirty women with infraorbital dark circles (predominant color: dark/brown) participated in this open-labeled study. The participants received eight sessions of 694-nm fractional Q-switched ruby laser treatment using a fluence of 3.0-3.5 J/cm(2), at an interval of 7 days. The melanin deposition in the lesional skin was observed in vivo using reflectance confocal microscopy (RCM)...
December 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27398005/infraorbital-dark-circles-a-review-of-the-pathogenesis-evaluation-and-treatment
#14
Ivan Vrcek, Omar Ozgur, Tanuj Nakra
Infraorbital dark circles represent a common and multifactorial challenge in the world of aesthetic medicine and are the result of a variety of factors including deep facial anatomy, soft tissue changes, as well as contributions from the skin. A variety of treatment options exist, and a customised management strategy can be developed for the particular anatomic changes present. A literature search using MEDLINE and non-MEDLINE sources was performed utilising keywords including: 'Dark circles' 'infraorbital dark circles', 'infraorbital pigment', 'under-eye circles' and 'lower eyelid bags'...
April 2016: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/27281881/-establishment-of-intervertebral-disc-degeneration-of-rabbits-by-using-minimally-invasive-acupuncture-and-rotary-cutting
#15
Weiwei Tan, Shenghua He, Zhitao Sun, Yeguang Wang, Jian Wang, Juyi Lai
OBJECTIVE: To investigate the feasibility of establishing intervertebral disc degeneration (IDD) model by using minimally invasive acupuncture and rotary-cutting. METHODS: Forty New Zealand white rabbits [male or female, (2.9 ± 0.3) kg in weight] were randomly divided into control group (n = 20) and experimental group (n = 20). No treatment was done in the control group; percutaneous puncture was performed on L4,5 and L5,6 intervertebral disc by using 18G needle under C-arm X-ray monitoring for rotary-cutting of nucleus pulposus to promote degeneration of the disc in the experimental group...
March 2016: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/27233352/use-of-transcutaneous-ultrasonography-to-characterize-ovarian-status-size-distribution-and-hierarchical-status-of-follicles-in-japanese-quail-coturnix-coturnix-japonica
#16
R M Sreesujatha, S Jeyakumar, A Kundu, Chellam Balasundaram
The present study was undertaken to evaluate the ovarian status of matured breeding female Japanese quail by means of B Mode portable ultrasound scanning. Active ovaries in various stages of hierarchical development and different morphological structure were observed. The large yellow follicles appeared as a cluster of dark circles with various intensity of hyperechoic concentric ring. Sonographically, these follicles were classified into F1, F2, and F3 measuring 16.20 ± 0.06 mm, 12.48 ± 0.09 mm, and 7...
September 15, 2016: Theriogenology
https://www.readbyqxmd.com/read/26984626/cuttlefish-see-shape-from-shading-fine-tuning-coloration-in-response-to-pictorial-depth-cues-and-directional-illumination
#17
Sarah Zylinski, D Osorio, Sonke Johnsen
Humans use shading as a cue to three-dimensional form by combining low-level information about light intensity with high-level knowledge about objects and the environment. Here, we examine how cuttlefish Sepia officinalis respond to light and shadow to shade the white square (WS) feature in their body pattern. Cuttlefish display the WS in the presence of pebble-like objects, and they can shade it to render the appearance of surface curvature to a human observer, which might benefit camouflage. Here we test how they colour the WS on visual backgrounds containing two-dimensional circular stimuli, some of which were shaded to suggest surface curvature, whereas others were uniformly coloured or divided into dark and light semicircles...
March 16, 2016: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/26967571/combination-of-microneedling-and-10-trichloroacetic-acid-peels-in-the-management-of-infraorbital-dark-circles
#18
George Kontochristopoulos, Anargyros Kouris, Eftychia Platsidaki, Vasiliki Markantoni, Maria Gerodimou, Christina Antoniou
BACKGROUND: Dark circles (DC), seen in the periorbital area, are defined as bilateral, round, homogeneous pigmented macules whose aetiology is thought to be multifactorial. Available treatments include bleaching creams, topical retinoic acid, chemical peels, lasers, autologous fat transplantation, injectable fillers and surgery (blepharoplasty). OBJECTIVE: To evaluate the efficacy and safety of a combination of microneedling and 10% trichloroacetic acid (TCA) peels in the treatment of DC...
October 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/26962392/periorbital-hyperpigmentation-a-comprehensive-review
#19
Rashmi Sarkar, Rashmi Ranjan, Shilpa Garg, Vijay K Garg, Sidharth Sonthalia, Shivani Bansal
Periorbital hyperpigmentation is a commonly encountered condition. There is very little scientific data available on the clinical profile and pathogenesis of periorbital hyperpigmentation. Periorbital hyperpigmentation is caused by various exogenous and endogenous factors. The causative factors include genetic or heredity, excessive pigmentation, postinflammatory hyperpigmentation secondary to atopic and allergic contact dermatitis, periorbital edema, excessive vascularity, shadowing due to skin laxity and tear trough associated with aging...
January 2016: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/26955124/prevalence-of-topical-steroid-misuse-among-rural-masses
#20
Amit Sinha, Sumit Kar, Nidhi Yadav, Bhushan Madke
BACKGROUND: A lot of cosmetic and Ayurvedic products containing unlabeled depigmenting agent and steroids are available readily over the counter sale. The side effects of these products are not documented and can lead to adverse effects of continuous usage. OBJECTIVE: By this study, we aimed to find out the true nature of the above problem and it's implication in the Indian rural scenario. METHODOLOGY: All patients attending dermatology department during the period of 3 months from May to June 2013 for skin diseases were enquired about unsupervised use of any cosmetic product on their facial skin, duration of use, any side effect experienced through the prescribed questionnaire...
January 2016: Indian Journal of Dermatology
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