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https://www.readbyqxmd.com/read/28092076/determination-of-trace-elements-in-cow-placenta-by-tungsten-coil-atomic-emission-spectrometry
#1
Daniel A Gonçalves, Ana C Soncin, George L Donati, Mirian C Dos Santos
Tungsten coil atomic emission spectrometry (WCAES) is used to determine trace levels of Mn (403.1 nm) and Cr (425.5 nm) in cow placenta. All samples were collected in Ilha Solteira, SP, Brazil. The instrumental setup is based on a tungsten filament extracted from 150 W, 15 V microscope light bulbs, a solid state power supply, fused silica lens, crossed Czerny-Turner spectrograph, and a thermoelectrically cooled charge-coupled device detector. The limits of detection (LOD) and quantification (LOQ) for Cr are 2 and 8 μg L(-1), and 20 and 60 μg L(-1) for Mn, respectively...
January 16, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28091333/an-ecological-approach-to-reducing-potentially-inappropriate-medication-use-canadian-deprescribing-network
#2
Cara Tannenbaum, Barbara Farrell, James Shaw, Steve Morgan, Johanna Trimble, Jane Currie, Justin Turner, Paula Rochon, James Silvius
Polypharmacy is growing in Canada, along with adverse drug events and drug-related costs. Part of the solution may be deprescribing, the planned and supervised process of dose reduction or stopping of medications that may be causing harm or are no longer providing benefit. Deprescribing can be a complex process, involving the intersection of patients, health care providers, and organizational and policy factors serving as enablers or barriers. This article describes the justification, theoretical foundation, and process for developing a Canadian Deprescribing Network (CaDeN), a network of individuals, organizations, and decision-makers committed to promoting the appropriate use of medications and non-pharmacological approaches to care, especially among older people in Canada...
January 16, 2017: Canadian Journal on Aging, la Revue Canadienne du Vieillissement
https://www.readbyqxmd.com/read/28090344/tasting-profile-affects-adoption-of-caloric-beverage-reduction-in-a-randomized-weight-loss-intervention
#3
G Turner-McGrievy, X Wang, B Popkin, D F Tate
OBJECTIVE: The aim of this study was to examine differences in rates of non-caloric beverage adoption by participants classified as sweet likers (SLs) or sweet dislikers (measured using a behavioural tasting task). METHODS: Data are a sub-study from a 6-month, three-group, randomized weight loss trial (CHOICE) (body mass index 36.3 ± 5.8 kg m(-2), 84% female, aged 42.2 ± 10.9 years, 53% African-American) comparing the replacement of caloric beverages with either non-caloric sweetened beverages (diet) or water (water) compared with a control group...
December 2016: Obesity Science & Practice
https://www.readbyqxmd.com/read/28090100/description-and-evaluation-of-an-mpharm-practice-based-experience-pilot-program
#4
Philip Winn, Christopher J Turner
Objective. To determine the level of support among pharmacists in central Scotland to serve as mentors and provide practice-based experience to students enrolled in a master of pharmacy degree program. Methods. A study was conducted during the 2011-2012 academic year in which first-year MPharm students in Scotland were paired with practicing pharmacists for 2 half-day visits per month. The students were integrated into the pharmacy workflow and engaged in activities ranging from date checking to counseling patients...
November 25, 2016: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/28089986/estimating-glomerular-filtration-rate-for-the-full-age-spectrum-from-serum-creatinine-and-cystatin-c
#5
Hans Pottel, Pierre Delanaye, Elke Schaeffner, Laurence Dubourg, Bjørn Odvar Eriksen, Toralf Melsom, Edmund J Lamb, Andrew D Rule, Stephen T Turner, Richard J Glassock, Vandréa De Souza, Luciano Selistre, Karolien Goffin, Steven Pauwels, Christophe Mariat, Martin Flamant, Natalie Ebert
BACKGROUND: We recently published and validated the new serum creatinine (Scr)-based full-age-spectrum equation (FAScrea) for estimating the glomerular filtration rate (GFR) for healthy and kidney-diseased subjects of all ages. The equation was based on the concept of normalized Scr and shows equivalent to superior prediction performance to the currently recommended equations for children, adolescents, adults and older adults. METHODS: Based on an evaluation of the serum cystatin C (ScysC) distribution, we defined normalization constants for ScysC (QcysC = 0...
January 15, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28089566/metformin-inhibits-hepatic-mtorc1-signaling-via-dose-dependent-mechanisms-involving-ampk-and-the-tsc-complex
#6
Jessica J Howell, Kristina Hellberg, Marc Turner, George Talbott, Matthew J Kolar, Debbie S Ross, Gerta Hoxhaj, Alan Saghatelian, Reuben J Shaw, Brendan D Manning
Metformin is the most widely prescribed drug for the treatment of type 2 diabetes. However, knowledge of the full effects of metformin on biochemical pathways and processes in its primary target tissue, the liver, is limited. One established effect of metformin is to decrease cellular energy levels. The AMP-activated protein kinase (AMPK) and mechanistic target of rapamycin (mTOR) complex 1 (mTORC1) are key regulators of metabolism that are respectively activated and inhibited in acute response to cellular energy depletion...
December 30, 2016: Cell Metabolism
https://www.readbyqxmd.com/read/28088505/gaps-in-the-public-s-knowledge-about-chronic-pain-representative-sample-of-hispanic-residents-from-five-states
#7
Barbara J Turner, Yuanyuan Liang, Natalia Rodriguez, Melissa A Valerio, Andrea Rochat, Jennifer S Potter, Paula Winkler
: Educating the general public about chronic pain and its care is a national health priority. We evaluated knowledge, attitudes, and beliefs (KAB) of a five-state, population-based sample of Hispanics aged 35-75 without chronic pain, representing over 8.8 million persons. A web-based survey assessed KAB using an adapted version of the Survey of Pain Attitudes-Brief and self-reported knowledge about chronic pain (nothing, a little, a lot). In unweighted analyses of participants (n=346), mean age was 52...
January 11, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28088026/current-ambient-concentrations-of-ozone-in-panama-modulate-the-leaf-chemistry-of-the-tropical-tree-ficus-insipida
#8
Gerald F Schneider, Alexander W Cheesman, Klaus Winter, Benjamin L Turner, Stephen Sitch, Thomas A Kursar
Tropospheric ozone (O3) is a major air pollutant and greenhouse gas, affecting carbon dynamics, ecological interactions, and agricultural productivity across continents and biomes. Elevated [O3] has been documented in tropical evergreen forests, the epicenters of terrestrial primary productivity and plant-consumer interactions. However, the effects of O3 on vegetation have not previously been studied in these forests. In this study, we quantified ambient O3 in a region shared by forests and urban/commercial zones in Panama and found levels two to three times greater than in remote tropical sites...
December 27, 2016: Chemosphere
https://www.readbyqxmd.com/read/28087549/engaging-stakeholders-and-target-groups-in-prioritising-a-public-health-intervention-the-creating-active-school-environments-case-online-delphi-study
#9
Katie L Morton, Andrew J Atkin, Kirsten Corder, Marc Suhrcke, David Turner, Esther M F van Sluijs
OBJECTIVES: Stakeholder engagement and public involvement are considered as integral to developing effective public health interventions and is encouraged across all phases of the research cycle. However, limited guidelines and appropriate tools exist to facilitate stakeholder engagement-especially during the intervention prioritisation phase. We present the findings of an online 'Delphi' study that engaged stakeholders (including young people) in the process of prioritising secondary school environment-focused interventions that aim to increase physical activity...
January 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28086917/resveratrol-regulates-neuro-inflammation-and-induces-adaptive-immunity-in-alzheimer-s-disease
#10
Charbel Moussa, Michaeline Hebron, Xu Huang, Jaeil Ahn, Robert A Rissman, Paul S Aisen, R Scott Turner
BACKGROUND: Treatment of mild-moderate Alzheimer's disease (AD) subjects (N = 119) for 52 weeks with the SIRT1 activator resveratrol (up to 1 g by mouth twice daily) attenuates progressive declines in CSF Aβ40 levels and activities of daily living (ADL) scores. METHODS: For this retrospective study, we examined banked CSF and plasma samples from a subset of AD subjects with CSF Aβ42 <600 ng/ml (biomarker-confirmed AD) at baseline (N = 19 resveratrol-treated and N = 19 placebo-treated)...
January 3, 2017: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/28085859/study-on-a-wideband-variable-aperture-high-resolution-scatterometer-for-planar-diffraction-grating-stray-light-measurement
#11
Jin Yang, Rui Zhang, Lu Yin, Ci Sun, Tianjiao Li
Stray light is one of the important factors for evaluating the quality of gratings. Therefore, it has become an important problem in the field of grating development to measure the stray light of planar diffraction gratings accurately. For that reason, a planar grating stray light testing instrument based on a Czerny-Turner (C-T) structure has been studied. On the premise of the low stray light of the instrument itself, the instrument is capable of measuring wideband, variable aperture, and high resolution stray light for planar gratings...
January 10, 2017: Applied Optics
https://www.readbyqxmd.com/read/28084735/real-time-screening-of-biocatalysts-in-live-bacterial-colonies
#12
Cunyu Yan, Fabio Parmeggiani, Emrys A Jones, Emmanuelle Claude, Shaneela A Hussain, Nicholas J Turner, Sabine L Flitsch, Perdita E Barran
Screening of bacterial colonies to identify new biocatalytic activities is a widely adopted tool in biotechnology, but is constrained by the requirements for colorimetric or tag-based detection methods. Herein we report a label-free screening platform using desorption electrospray ionization coupled with ion mobility mass spectrometry imaging (DESI-IM-MS). The screening method is demonstrated for both ammonia lyases and P450 monooxygenases expressed within live bacterial colonies and is shown to enable multiplexing of enzyme variants and substrate libraries simultaneously...
January 13, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28084093/time-and-temperature-affect-glycolysis-in-blood-samples-regardless-of-fluoride-based-preservatives-a-potential-underestimation-of-diabetes
#13
Mary Stapleton, Niamh Daly, Ruth O'Kelly, Michael J Turner
Background The inhibition of glycolysis prior to glucose measurement is an important consideration when interpreting glucose tolerance tests. This is particularly important in gestational diabetes mellitus where prompt diagnosis and treatment is essential. A study was planned to investigate the effect of preservatives and temperature on glycolysis. Methods Blood samples for glucose were obtained from consented females. Lithium heparin and fluoride-EDTA samples transported rapidly in ice slurry to the laboratory were analysed for glucose concentration and then held either in ice slurry or at room temperature for varying time intervals...
January 1, 2017: Annals of Clinical Biochemistry
https://www.readbyqxmd.com/read/28082588/plant-soil-feedback-and-the-maintenance-of-diversity-in-mediterranean-climate-shrublands
#14
François P Teste, Paul Kardol, Benjamin L Turner, David A Wardle, Graham Zemunik, Michael Renton, Etienne Laliberté
Soil biota influence plant performance through plant-soil feedback, but it is unclear whether the strength of such feedback depends on plant traits and whether plant-soil feedback drives local plant diversity. We grew 16 co-occurring plant species with contrasting nutrient-acquisition strategies from hyperdiverse Australian shrublands and exposed them to soil biota from under their own or other plant species. Plant responses to soil biota varied according to their nutrient-acquisition strategy, including positive feedback for ectomycorrhizal plants and negative feedback for nitrogen-fixing and nonmycorrhizal plants...
January 13, 2017: Science
https://www.readbyqxmd.com/read/28082310/very-early-onset-ibd-how-very-different-on-average
#15
EDITORIAL
Dan Turner, Aleixo M Muise
No abstract text is available yet for this article.
January 12, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28082261/hydrogel-versus-bare-platinum-coils-in-patients-with-large-or-recurrent-aneurysms-prone-to-recurrence-after-endovascular-treatment-a-randomized-controlled-trial
#16
J Raymond, R Klink, M Chagnon, S L Barnwell, A J Evans, J Mocco, B H Hoh, A S Turk, R D Turner, H Desal, D Fiorella, S Bracard, A Weill, F Guilbert, S Lanthier, A J Fox, T E Darsaut, P M White, D Roy
BACKGROUND AND PURPOSE: Some patients are at high risk of aneurysm recurrence after endovascular treatment: patients with large aneurysms (Patients Prone to Recurrence After Endovascular Treatment PRET-1) or with aneurysms that have previously recurred after coiling (PRET-2). We aimed to establish whether the use of hydrogel coils improved efficacy outcomes compared with bare platinum coils. MATERIALS AND METHODS: PRET was an investigator-led, pragmatic, multicenter, parallel, randomized (1:1) trial...
January 12, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28081684/implementation-and-outcomes-of-a-new-safeguarding-pathway-for-vulnerable-adults-presenting-to-sexual-health-services
#17
Nisha Mody, Catherine Kirby, Patrice Grech, Hermione Thompson, Frances Turner, Lorette Runacres, Elizabeth Hamlyn
Adult safeguarding is the process of protecting vulnerable adults from harm or exploitation. In 2014, our sexual health clinic implemented a new adult safeguarding pathway, including an adult safeguarding proforma, an electronic database and a monthly adult safeguarding meeting. We conducted a retrospective case note review of patients entered onto the safeguarding database and found that greater numbers of adults were identified as vulnerable following the introduction of this pathway. Many required referral for onward support, highlighting the importance of robust safeguarding procedures in a sexual health setting...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28081200/fitter-women-did-not-have-attenuated-hemodynamic-responses-to-psychological-stress-compared-with-age-matched-women-with-lower-levels-of-fitness
#18
Sisitha U Jayasinghe, Susan J Torres, Mais Hussein, Steve F Fraser, Gavin W Lambert, Anne I Turner
According to the 'cross stressor adaptation hypothesis', regular exercise acts as a buffer against the detrimental effects of stress. Nevertheless, evidence that higher levels of cardiorespiratory fitness moderate hemodynamic responses to acute psychological stress is inconclusive, especially in women. Women aged 30-50 years (in the mid-follicular phase of the menstrual cycle) with higher (n = 17) and lower (n = 17) levels of fitness were subjected to a Trier Social Stress Test (TSST). Continuous, non-invasive measurements were made of beat-to-beat, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), stroke volume (SV), cardiac output (CO), left ventricular ejection time (LVET), maximum slope, pulse interval (PI) and total peripheral resistance (TPR)...
2017: PloS One
https://www.readbyqxmd.com/read/28080077/dogs-canis-familiaris-attention-to-human-perception-influence-of-breed-groups-and-life-experiences
#19
Marianne T E Heberlein, Dennis C Turner, Marta B Manser
Attending to the perception of others may help individuals gaining information from conspecifics, or help in competitive situations. Dogs (Canis familiaris) are attentive to humans' signals and their attentional state. We investigated whether dogs of different breed groups differ in their ability to pay attention to human's perception, first according to the genetic relatedness between dog breeds, and second according to working style differences. Once dogs had learned to leave forbidden food on the floor, they were confronted with 2 food items to which only they had unrestricted visual access...
January 12, 2017: Journal of Comparative Psychology
https://www.readbyqxmd.com/read/28078659/summer-research-training-provides-effective-tools-for-underrepresented-minorities-to-obtain-doctoral-level-degrees
#20
Oluwatoyin A Asojo, Ashish Damania, Teri L Turner, Gayle Slaughter, Kendal D Hirschi
The ethnic, racial, and cultural diversity of the USA is not reflected in its healthcare and biomedical workforce. Undergraduate research programs are used to encourage underrepresented minorities to pursue training for biomedical careers, but there is limited published data on doctoral degree completion rates by participants in these programs. This study evaluates the attainment of doctoral degrees by a NIH-funded cohort of undergraduates from the 1998-2002 Baylor College of Medicine's Summer Medical Research Training (SMART) program...
January 11, 2017: Journal of Racial and Ethnic Health Disparities
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