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https://www.readbyqxmd.com/read/28737897/biogenic-hydroxyapatite-a-new-material-for-the-preservation-and-restoration-of-the-built-environment
#1
Ronald Joseph Turner, Joanna C Renshaw, Andrea Hamilton
Ordinary Portland Cement (OPC) is by weight the world's most produced man-made material, and consequently is used in a variety of applications in environments ranging from buildings, to nuclear wasteforms, and within the human body. In this paper, we present for the first time the direct deposition of biogenic hydroxyapatite onto the surface of OPC, in a synergistic process which relies upon the unique properties of the cement substrate. The synthesised hydroxyapatite is very similar to that found in nature; having a crystallite size, iron and carbonate substitution, and a semi-crystalline structure which identify that this biogenic hydroxyapatite is akin to that found in natural bone and tooth enamel...
July 24, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28736822/congenital-heart-disease-and-cardiac-procedural-outcomes-in-patients-with-trisomy-21-and-turner-syndrome
#2
Raysa Morales-Demori
Congenital heart disease (CHD) is present in approximately 50% of patients with trisomy 21 (T21) and Turner syndrome (TS). According to the American Academy of Pediatrics, every patient with these genetic disorders should have a postnatal echocardiogram. T21 is usually associated with atrioventricular (30%-60%), atrial (16%-21%), or ventricular septal defects (14%-27%). TS is usually associated with left-sided heart disease. However, the spectrum of CHD in these genetic disorders is wider than those mentioned lesions...
July 24, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28735247/can-nurses-rise-to-the-public-health-challenge-how-a-novel-solution-in-nurse-education-can-address-this-contemporary-question
#3
EDITORIAL
Angela L Turner-Wilson, Anne M Mills, Karen Rees
This paper raises the problem of how improvements in health outcomes, a key component in many governments' strategies, can be achieved. The work highlights a novel undergraduate educational approach which offers solutions to public health challenges within nursing. Against the backdrop of one UK university institution it discusses approaches that can guide nursing students towards a deeper understanding and engagement within the principles of public health. It then proposes how nurses can use their learning to become leaders of health improvement...
July 12, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28734844/tlr3-blockade-in-rhinovirus-induced-experimental-asthma-exacerbations-a-randomized-controlled-study
#4
Philip E Silkoff, Susan Flavin, Robert Gordon, Mathew J Loza, Peter J Sterk, Rene Lutter, Zuzana Diamant, Ronald B Turner, Brian J Lipworth, David Proud, Dave Singh, Andreas Eich, Vibeke Backer, James E Gern, Christian Herzmann, Scott A Halperin, Tjeert T Mensinga, Alfred M Del Vecchio, Patrick Branigan, Lani San Mateo, Frédéric Baribaud, Elliot S Barnathan, Sebastian L Johnston
BACKGROUND: Human rhinoviruses (HRV) commonly precipitate asthma exacerbations. TLR3, an innate pattern-recognition receptor, is triggered by HRV driving inflammation that may worsen asthma. OBJECTIVE: To evaluate an inhibitory monoclonal antibody to TLR3, CNTO3157, on experimental HRV-16 inoculation in healthy and asthmatic subjects. METHODS: In this double-blind multicenter randomized parallel-group study in North America and Europe, healthy and mild-moderate stable asthmatic subjects received single or multiple doses of CNTO 3157 or placebo, respectively, and were then inoculated with HRV-16 within 72 hours...
July 19, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28734806/snora21-an-oncogenic-small-nucleolar-rna-with-a-prognostic-biomarker-potential-in-human-colorectal-cancer
#5
Kazuhiro Yoshida, Shusuke Toden, Wenhao Weng, Kunitoshi Shigeyasu, Jinsei Miyoshi, Jacob Turner, Takeshi Nagasaka, Yanlei Ma, Tetsuji Takayama, Toshiyoshi Fujiwara, Ajay Goel
BACKGROUND: Emerging evidence indicates that small nucleolar RNAs (snoRNAs) play a central role in oncogenesis. Herein, we systematically evaluated expression profiles of snoRNAs in colorectal cancer (CRC) and investigated their clinical and functional role in this malignancy. METHODS: We compared expression levels of snoRNAs between cancer and normal tissues using publicly available datasets and identified the most differentially expressed and commonly upregulated snoRNAs in CRC...
July 12, 2017: EBioMedicine
https://www.readbyqxmd.com/read/28734559/a-systematic-review-and-meta-analysis-of-written-self-administered-psychosocial-interventions-among-adults-with-a-physical-illness
#6
REVIEW
Sylvie D Lambert, Lisa Beatty, Patrick McElduff, Janelle V Levesque, Catalina Lawsin, Paul Jacobsen, Jane Turner, Afaf Girgis
OBJECTIVE: The cost of implementing professionally-led psychosocial interventions has limited their integration into routine care. To enhance the translation of effective psychosocial interventions in routine care, a self-administered format is sometimes used. The meta-analysis examined the efficacy of written self-administered, psychosocial interventions to improve outcomes among individuals with a physical illness. METHODS: Studies comparing a written self-administered intervention to a control group were identified through electronic databases searching...
July 8, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28734362/discrimination-of-bacteria-by-rapid-sensing-their-metabolic-volatiles-using-an-aspiration-type-ion-mobility-spectrometer-a-ims-and-gas-chromatography-mass-spectrometry-gc-ms
#7
Ileana Andreea Ratiu, Victor Bocos-Bintintan, Adrian Patrut, Victor Hugo Moll, Matthew Turner, C L Paul Thomas
The objective of our study was to investigate whether one may quickly and reliably discriminate different microorganism strains by direct monitoring of the headspace atmosphere above their cultures. Headspace samples above a series of in vitro bacterial cultures were directly interrogated using an aspiration type ion mobility spectrometer (a-IMS), which produced distinct profiles ("fingerprints") of ion currents generated simultaneously by the detectors present inside the ion mobility cell. Data processing and analysis using principal component analysis showed net differences in the responses produced by volatiles emitted by various bacterial strains...
August 22, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28733164/the-role-of-oxysterol-binding-protein-and-its-related-proteins-in-cancer
#8
REVIEW
Ximing Du, Nigel Turner, Hongyuan Yang
Oxysterol-binding protein (OSBP) and its related proteins (ORPs) constitute a large, evolutionarily conserved family of lipid-binding proteins that are associated with a wide range of cellular activities. The core function of OSBP/ORPs appears to be moving lipids between cellular membranes in a non-vesicular manner. Recent studies have unveiled a novel, counter-transport mechanism of cellular lipid transfer mediated by OSBP/ORPs at the membrane contact sites that involves phosphatidylinositol 4-phosphate. Importantly, the OSBP/ORPs family has also been implicated in cell signalling pathways and cancer development...
July 18, 2017: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/28731272/short-term-toxicity-of-1-methylnaphthalene-to-americamysis-bahia-and-five-deep-sea-crustaceans
#9
Anthony Knap, Nicholas R Turner, Gopal Bera, D Abigail Renegar, Tamara Frank, Jose Sericano, Bernhard M Riegl
There are few studies that have evaluated hydrocarbon toxicity to vertically migrating deep-sea micronekton. Crustaceans were collected alive using a 9 m(2) Tucker trawl with a thermally insulated cod end and returned to the laboratory in 10 °C seawater. Toxicity of the polycyclic aromatic hydrocarbon 1-methylnapthalene to Americamysis bahia, Janicella spinacauda, Systellaspis debilis, Sergestes sp., Sergia sp., and a euphausid sp. was assessed in a constant exposure toxicity test utilizing a novel passive dosing toxicity testing protocol...
July 21, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28729733/extreme-coastal-erosion-enhanced-by-anomalous-extratropical-storm-wave-direction
#10
Mitchell D Harley, Ian L Turner, Michael A Kinsela, Jason H Middleton, Peter J Mumford, Kristen D Splinter, Matthew S Phillips, Joshua A Simmons, David J Hanslow, Andrew D Short
Extratropical cyclones (ETCs) are the primary driver of large-scale episodic beach erosion along coastlines in temperate regions. However, key drivers of the magnitude and regional variability in rapid morphological changes caused by ETCs at the coast remain poorly understood. Here we analyze an unprecedented dataset of high-resolution regional-scale morphological response to an ETC that impacted southeast Australia, and evaluate the new observations within the context of an existing long-term coastal monitoring program...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28729174/challenges-and-strategies-to-facilitate-formulation-development-of-pediatric-drug-products-safety-qualification-of-excipients
#11
Lorrene A Buckley, Smita Salunke, Karen Thompson, Gerri Baer, Darren Fegley, Mark A Turner
A public workshop entitled "Challenges and strategies to facilitate formulation development of pediatric drug products" focused on current status and gaps as well as recommendations for risk-based strategies to support the development of pediatric age-appropriate drug products. Representatives from industry, academia, and regulatory agencies discussed the issues within plenary, panel, and case-study breakout sessions. By enabling practical and meaningful discussion between scientists representing the diversity of involved disciplines (formulators, nonclinical scientists, clinicians, and regulators) and geographies (eg, US, EU), the Excipients Safety workshop session was successful in providing specific and key recommendations for defining paths forward...
July 17, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28728602/robot-assisted-training-for-the-upper-limb-after-stroke-ratuls-study-protocol-for-a-randomised-controlled-trial
#12
Helen Rodgers, Lisa Shaw, Helen Bosomworth, Lydia Aird, Natasha Alvarado, Sreeman Andole, David L Cohen, Jesse Dawson, Janet Eyre, Tracy Finch, Gary A Ford, Jennifer Hislop, Steven Hogg, Denise Howel, Niall Hughes, Hermano Igo Krebs, Christopher Price, Lynn Rochester, Elaine Stamp, Laura Ternent, Duncan Turner, Luke Vale, Elizabeth Warburton, Frederike van Wijck, Scott Wilkes
BACKGROUND: Loss of arm function is a common and distressing consequence of stroke. We describe the protocol for a pragmatic, multicentre randomised controlled trial to determine whether robot-assisted training improves upper limb function following stroke. METHODS/DESIGN: Study design: a pragmatic, three-arm, multicentre randomised controlled trial, economic analysis and process evaluation. SETTING: NHS stroke services. PARTICIPANTS: adults with acute or chronic first-ever stroke (1 week to 5 years post stroke) causing moderate to severe upper limb functional limitation...
July 20, 2017: Trials
https://www.readbyqxmd.com/read/28727658/white-cell-and-marrow-imaging-subtracting-uncertainty
#13
Chelsey Turner, Alison A Bolster, Carolyn L Paterson, Hugh J Wallace
A subtraction method for assessments of dual-isotope indium-111 (In)-labelled white cell and Tc-nanocoll was proposed, and following a pilot study was introduced in routine service to improve the confidence of reporters. This technical note describes a simple technique to produce subtraction images from routinely acquired images to investigate and exclude post joint replacement infection. Labelled leucocytes (with In) show areas of increased white cell accumulation, whereas Tc-nanocoll images show bone marrow distribution...
July 19, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28726837/solve-antarctica-s-sea-ice-puzzle
#14
John Turner, Josefino Comiso
No abstract text is available yet for this article.
July 19, 2017: Nature
https://www.readbyqxmd.com/read/28726450/charles-l-brewer-award-for-distinguished-teaching-of-psychology-regan-a-r-gurung
#15
(no author information available yet)
The American Psychological Foundation (APF) Charles L. Brewer Award for Distinguished Teaching of Psychology recognizes exemplary career contributions to the teaching of psychology. The 2017 recipient of the Charles L. Brewer Award for Distinguished Teaching of Psychology is Regan A. R. Gurung, PhD. Terence M. Keane, PhD, president of the APF, will present the APF Charles L. Brewer Award for Distinguished Teaching of Psychology at the 125th Annual Convention of the American Psychological Association on August 4, 2017, at 4:00 p...
July 2017: American Psychologist
https://www.readbyqxmd.com/read/28726449/gold-medal-award-for-life-achievement-in-the-science-of-psychology-lynn-nadel
#16
(no author information available yet)
The American Psychological Foundation (APF) Gold Medal Awards recognize distinguished and engaging records of accomplishment in 4 areas of psychology. The 2017 recipient of the Gold Medal Award for Life Achievement in the Science of Psychology is Lynn Nadel, PhD. Terence M. Keane, PhD, president of the APF, will present the APF Gold Medal Awards at the 125th Annual Convention of the American Psychological Association on August 4, 2017, at 4:00 p.m. Members of the 2017 APF Board of Trustees are Terence M. Keane, PhD, president; Melba J...
July 2017: American Psychologist
https://www.readbyqxmd.com/read/28726448/gold-medal-award-for-life-achievement-in-psychology-in-the-public-interest-joseph-everett-trimble
#17
(no author information available yet)
The American Psychological Foundation (APF) Gold Medal Awards recognize distinguished and engaging records of accomplishment in 4 areas of psychology. The 2017 recipient of the Gold Medal Award for Life Achievement in Psychology in Public Interest is Joseph Everett Trimble, PhD. Terence M. Keane, PhD, president of the APF, will present the APF Gold Medal Awards at the 125th Annual Convention of the American Psychological Association on August 4, 2017, at 4:00 p.m. Members of the 2017 APF Board of Trustees are: Terence M...
July 2017: American Psychologist
https://www.readbyqxmd.com/read/28726447/gold-medal-award-for-life-achievement-in-the-practice-of-psychology-rodney-r-baker
#18
(no author information available yet)
The American Psychological Foundation (APF) Gold Medal Awards recognize distinguished and engaging records of accomplishment in 4 areas of psychology. The 2017 recipient of the Gold Medal Award for Life Achievement in the Practice of Psychology is Rodney R. Baker, PhD. Terence M. Keane, PhD, president of the APF, will present the APF Gold Medal Awards at the 125th Annual Convention of the American Psychological Association on August 4, 2017, at 4:00 p.m. Members of the 2017 APF Board of Trustees are: Terence M...
July 2017: American Psychologist
https://www.readbyqxmd.com/read/28726446/gold-medal-award-for-life-achievement-in-the-application-of-psychology-robert-j-gatchel
#19
(no author information available yet)
The American Psychological Foundation (APF) Gold Medal Awards recognize distinguished and engaging records of accomplishment in 4 areas of psychology. The 2017 Recipient of the Gold Medal Award for Life Achievement in the Application of Psychology is Robert J. Gatchel, PhD, ABPP. Terence M. Keane, PhD, president of the APF, will present the APF Gold Medal Awards at the 125th Annual Convention of the American Psychological Association on August 4, 2017, at 4:00 p.m. Members of the 2017 APF Board of Trustees are Terence M...
July 2017: American Psychologist
https://www.readbyqxmd.com/read/28725213/can-brain-natriuretic-peptides-and-osteoprotegerin-serve-as-biochemical-markers-for-the-detection-of-aortic-pathology-in-children-and-adolescents-with-turner-syndrome
#20
REVIEW
Meenal Mavinkurve, Clodagh S O'Gorman
Turner syndrome (TS) is a chromosomal disorder that affects 1:2,000 females. It results from either the complete or partial loss of the X chromosome as well as other aberrations. Clinical features of TS include short stature, delayed puberty, and congenital cardiac malformations. TS children also have an increased prevalence of cardiometabolic risk factors, which predisposes them to complications like coronary artery disease, cerebrovascular-related deaths, and aortic dissection. Early cardiac imaging, such as echocardiography and cardiac magnetic resonance imaging, are recommended to detect underlying aortic pathology...
2017: Frontiers in Endocrinology
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