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Corneal refractive therapy

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https://www.readbyqxmd.com/read/28068444/effectiveness-of-an-eyelid-thermal-pulsation-procedure-to-treat-recalcitrant-dry-eye-symptoms-after-laser-vision-correction
#1
Craig S Schallhorn, Julie M Schallhorn, Stephen Hannan, Steven C Schallhorn
PURPOSE: To provide an initial retrospective evaluation of the effectiveness of a thermal pulsation system to treat intractable patient-reported dye eye symptoms following laser vision correction. METHODS: A total of 109 eyes of 57 patients underwent thermal pulsation therapy (LipiFlow; TearScience, Morrisville, NC) for the treatment of dry eye symptoms following laser vision correction. A standardized dry eye questionnaire, the Standard Patient Evaluation of Eye Dryness (SPEED II), was administered to all patients before and after thermal pulsation therapy...
January 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28009792/clinical-features-in-children-with-posterior-polymorphous-corneal-dystrophy
#2
Ye Jin Ahn, Soon Il Choi, Hae Ri Yum, Sun Young Shin, Shin Hae Park
PURPOSE: To describe clinical features in children diagnosed with posterior polymorphous corneal dystrophy (PPCD) in their first or second decade of life. METHODS: A retrospective study was performed with the medical records of seven unrelated Korean pediatric patients who were diagnosed with PPCD and were followed up for a minimum of 3 years. Thorough ocular examinations were performed, including best-corrected visual acuity, intraocular pressure, refractive and keratometric measurements, slit-lamp biomicroscopy, and specular microscopy at all visits...
December 22, 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28003981/phakic-posterior-chamber-intraocular-lens-for-unilateral-high-myopic-amblyopia-in-chinese-pediatric-patients
#3
Jing Zhang, Jin-Rong Li, Zi-Dong Chen, Min-Bin Yu, Ke-Ming Yu
AIM: To assess the outcomes of posterior chamber implantable collamer lens (ICL) implantation in Chinese pediatric patients with unilateral high myopic amblyopia. METHODS: Eleven eyes of 11 amblyopic patients aged 11.02±3.34y underwent ICL (model V4, Staar Surgical Inc.) implantation to treat unilateral anisometropia were studied. Visual acuity, cycloplegic refraction, contrast sensitivity, stereopsis, intraocular pressure (IOP), vaulting, corneal endothelial cell count and complications were evaluated...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/27926756/cutting-and-decellularization-of-multiple-corneal-stromal-lamellae-for-the-bioengineering-of-endothelial-grafts
#4
Zhiguo He, Fabien Forest, Aurélien Bernard, Anne-Sophie Gauthier, Romain Montard, Michel Peoc'h, Clotilde Jumelle, Emilie Courrier, Chantal Perrache, Philippe Gain, Gilles Thuret
Purpose: Engineered corneal endothelial grafts able to provide numerous functional endothelial cells for the restoration of corneal transparency would be a worthwhile way of replacing donor tissue, which is extremely scarce. The grafts are simply constructed: a biocompatible thin and transparent carrier colonized by a monolayer of cultured endothelial cells (ECs). Here we describe a process able to obtain appropriate carriers by recycling human corneas unsuitable for graft in their original state, but liable to provide multiple thin lamellae when cut with a femtosecond laser as used in refractive surgery...
December 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27904945/-sarcoidosis-and-uveitis-an-update
#5
REVIEW
J G Garweg
Ocular involvement in sarcoidosis is present in up to one third of patients and is frequently manifested before the underlying systemic disease has been diagnosed. With a view to the therapeutic consequences an early diagnosis of the underlying disease is advantageous. In cases of visual loss early diagnostic measures include invasive procedures, such as ultrasound-guided bronchoalveolar lavage and transbronchial biopsy, if nodular conjunctival or cutaneous manifestations which would confirm the diagnosis are not present...
November 30, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27873014/binocular-function-changes-produced-in-response-to-overnight-orthokeratology
#6
Gema Felipe-Marquez, María Nombela-Palomo, Catalina Palomo-Álvarez, Isabel Cacho, Amelia Nieto-Bona
PURPOSE: To analyze the binocular function changes produced on subjects undergoing overnight orthokeratology (OK) treatment over short-term (3 months) and long-term (3 years) wear. METHODS: A prospective, longitudinal study on young adult subjects with low to moderate myopia was carried out. Binocular function was assessed by the following sequence of tests: Distance and near horizontal phoria (Von Graefe technique), distance and near horizontal vergence ranges (Risley rotary prisms), accommodative convergence/accommodation (AC/A) ratio (gradient method) and the near point of convergence (standard push-up technique)...
January 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27684823/clinical-evaluation-of-deep-anterior-lamellar-keratoplasty-using-glycerol-cryopreserved-corneal-tissues-for-refractory-herpetic-stromal-keratitis-an-observational-study
#7
Xin Liu, Qi Zhou, Xinyu Huang, Zhenxing Liu, Yanlong Bi
The study aimed to evaluate the therapeutic effects of deep anterior lamellar keratoplasty (DALK) using glycerol-cryopreserved corneal tissues (GCCTs) in patients with refractive herpes simplex keratitis (HSK). This article was a retrospective, noncomparative, and interventional case series. Patients with HSK underwent DALK using GCCTs at Shanghai Tongji Hospital from 2012 to 2015. The best spectacle corrected visual acuity, recurrent inflammation, graft status, postoperative central graft thickness, and pre/postoperative complications were detected...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27456563/-riboflavin-photoprotection-with-cross-linking-effect-in-photorefractive-ablation-of-the-cornea
#8
I M Kornilovsky, A I Sultanova, A A Burtsev
UNLABELLED: Photorefractive ablation is inevitably accompanied by oxidative stress of the cornea and weakening of its biomechanical and photoprotective properties. AIM: To validate the expediency of riboflavin use in photorefractive ablation for photoprotection of the cornea and cross-linking. MATERIAL AND METHODS: The effects of riboflavin use in photorefractive ablation was first studied in a series of in vitro and in vivo experiments performed on 56 eyes of 28 rabbits, and then on 232 eyes of 142 patients with different degrees of myopia...
May 2016: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/27450739/thymosin-beta-4-a-potential-novel-therapy-for-neurotrophic-keratopathy-dry-eye-and-ocular-surface-diseases
#9
G Sosne, D Rimmer, H K Kleinman, G Ousler
Chronic ocular surface diseases such as dry eye, blepharitis, and neurotrophic keratopathies represent a significant and a growing therapeutic challenge. The basis of this expanding prevalence is multifactorial and may due to issues such as an aging population, an increasing use of video display terminals, and increases in frequency of refractive surgeries. The growing incidence of diseases such as diabetes may also be a contributing factor. Current treatments for ocular surface disease include artificial tears, lubricants, tear duct plugs, steroids, antibiotics, cyclosporine, scleral lenses, and serum tears...
2016: Vitamins and Hormones
https://www.readbyqxmd.com/read/27134906/evaluation-of-ocular-side-effects-in-the-patients-on-topiramate-therapy-for-control-of-migrainous-headache
#10
Omid Hesami, Seyedeh Simindokht Hosseini, Nasim Kazemi, Seyed-Mostafa Hosseini-Zijoud, Nahid Beladi Moghaddam, Farhad Assarzadegan, Sara Mokhtari, Shahrzad Fakhraee
INTRODUCTION: Topiramate, a sulfa-derivative monosaccharide, is an antiepileptic drug which is administered in the control of migraine. It is reported to cause various ocular side effects such as visual field defect and myopic shift. To investigate the alterations in refractive error, properties of the cornea and changes in the anterior chamber in patients that receive Topiramate for migraine control. MATERIALS AND METHODS: This is a hospital-based, non-interventional, observational study that is conducted at Imam Hossein Hospital, affiliated to Shahid Beheshti University of Medical Sciences, Department of Neurology, in collaboration with the department of Ophthalmology...
March 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27051527/corneal-based-surgical-presbyopic-therapies-and-their-application-in-pseudophakic-patients
#11
REVIEW
Grace L Paley, Roy S Chuck, Linda M Tsai
Purpose. The purpose of this review is to provide a summary of laser refractive surgery and corneal inlay approaches to treat presbyopia in patients after cataract surgery. Summary. The presbyopic population is growing rapidly along with increasing demands for spectacle independence. This review will focus on the corneal-based surgical options to address presbyopia including various types of corneal intrastromal inlays and laser ablation techniques to generate either a multifocal cornea ("PresbyLASIK") or monovision...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27051478/corneal-changes-after-collagen-crosslinking-for-keratoconus-using-dual-scheimpflug-imaging
#12
Mohammad Mehdi Sadoughi, Sepehr Feizi, Siamak Delfazayebaher, Alireza Baradaran-Rafii, Bahram Einollahi, Camelia Shahabi
PURPOSE: To evaluate corneal changes after collagen crosslinking (CXL) therapy for keratoconus (KCN) using the Galilei dual Scheimpflug analyzer. METHODS: This prospective, nonrandomized clinical study included 35 eyes of 32 keratoconus patients who had undergone CXL. The eyes were saturated with riboflavin solution and were subjected for 30 minutes to ultraviolet-A (UV-A) light with irradiance of 3 mW/cm(2). Effectiveness of the treatment was assessed by measuring uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), manifest cylinder/sphere, keratometry, pachymetry, posterior and anterior elevations by the Galilei dual Scheimpflug analyzer...
October 2015: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/26932750/anti-vascular-endothelial-growth-factor-vegf-drugs-for-treatment-of-retinopathy-of-prematurity
#13
REVIEW
Mari Jeeva Sankar, Jhuma Sankar, Manisha Mehta, Vishnu Bhat, Renuka Srinivasan
BACKGROUND: Vascular endothelial growth factor (VEGF) plays a key role in angiogenesis in fetal life. Recently, researchers have attempted to use anti-VEGF agents for the treatment of retinopathy of prematurity (ROP), a vasoproliferative disorder. There is currently uncertainty regarding the safety and efficacy of these agents in preterm infants with ROP. OBJECTIVES: To evaluate the efficacy and safety of anti-VEGF drugs when used either as monotherapy, i.e. without concomitant cryotherapy or laser therapy or in combination with planned cryo/laser therapy in preterm infants with type 1 ROP (defined as zone I any stage with plus disease, zone I stage 3 with or without plus disease or zone II stage 2 or 3 with plus disease)...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26779895/pluripotent-stem-cells-and-other-innovative-strategies-for-the-treatment-of-ocular-surface-diseases
#14
REVIEW
Johanna Erbani, Daniel Aberdam, Jerome Larghero, Valérie Vanneaux
The cornea provides two thirds of the refractive power of the eye and protection against insults such as infection and injury. The outermost tissue of the cornea is renewed by stem cells located in the limbus. Depletion or destruction of these stem cells may lead to blinding limbal stem cell deficiency (LSCD) that concerns millions of patients around the world. Innovative strategies based on adult stem cell therapies have been developed in the recent years but they are still facing numerous unresolved issues, and the long term results can be deceiving...
April 2016: Stem Cell Reviews
https://www.readbyqxmd.com/read/26605237/evaluation-of-the-outcomes-of-corneal-collagen-cross-linking-in-progressive-keratoconic-eyes
#15
Kobra Nasrollahi, Mohammad Ghoreishi, Shahriar Hanjani, Hamidreza Ziaie, Mohadeseh Mohammadinia, Majid Kabiri, Maryam Bahadoran
BACKGROUND: Corneal collagen cross-linking (CXL) is gaining popularity as a treatment in arresting the progression of keratoconus. It is a relatively new therapy using ultraviolet-A (UVA) with a photosensitizer to increase corneal stiffness. The purpose of this study was to evaluate visual, keratometric and topographic outcomes after corneal CXL in progressive keratoconic eyes. MATERIALS AND METHODS: In this prospective nonrandomized clinical study, 140 eyes of 110 patients with progressive keratoconus were treated by combined riboflavin/UVA CXL...
2015: Advanced Biomedical Research
https://www.readbyqxmd.com/read/26200489/central-and-peripheral-corneal-power-change-in-myopic-orthokeratology-and-its-relationship-with-2-year-axial-length-change
#16
Yuanyuan Zhong, Zhi Chen, Feng Xue, Huamao Miao, Xingtao Zhou
PURPOSE: We assessed the relationship between axial length (AL) change and corneal refractive power change induced by orthokeratology (ortho-k) contact lens wear. METHODS: A total of 88 myopic children aged 7 to 12 years were fitted with ortho-k lenses for overnight wear. Axial length was measured before enrollment and every 6 months after initiation of lens wear up to 24 months. Corneal apical refractive power and the mean power of each concentric ring from 0.5 to 7...
July 2015: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/26197361/progress-in-corneal-wound-healing
#17
REVIEW
Alexander V Ljubimov, Mehrnoosh Saghizadeh
Corneal wound healing is a complex process involving cell death, migration, proliferation, differentiation, and extracellular matrix remodeling. Many similarities are observed in the healing processes of corneal epithelial, stromal and endothelial cells, as well as cell-specific differences. Corneal epithelial healing largely depends on limbal stem cells and remodeling of the basement membrane. During stromal healing, keratocytes get transformed to motile and contractile myofibroblasts largely due to activation of transforming growth factor-β (TGF-β) system...
November 2015: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/26189097/stabilization-in-early-adult-onset-myopia-with-corneal-refractive-therapy
#18
José M González-Méijome, Gonzalo Carracedo, Daniela Lopes-Ferreira, Miguel A Faria-Ribeiro, Sofia C Peixoto-de-Matos, António Queirós
PURPOSE: To describe the stabilization of early adult-onset myopia in three university students after initiating orthokeratology treatment with corneal refractive therapy contact lenses. METHODS: Three Caucasian early adult-onset progressing myopic subjects (1 male, 2 females) were fitted with corneal refractive therapy lenses to correct myopia between -1.50 and -2.50 D of sphere using Paragon CRT (Paragon Vision Sciences, Mesa, AZ) lenses for overnight orthokeratology...
February 2016: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/26158925/hydrogel-inlay-for-presbyopia-objective-and-subjective-visual-outcomes
#19
Aeri Yoo, Jae Yong Kim, Myoung Joon Kim, Hungwon Tchah
PURPOSE: To evaluate changes in visual performance and ocular optical quality after implantation of a corneal hydrogel inlay as a treatment for presbyopia. METHODS: A Raindrop Near Vision Inlay (ReVision Optics, Lake Forest, CA) was implanted monocularly on the stromal bed of a femtosecond laser-assisted generated corneal flap of non-dominant eyes of 22 patients with emmetropic presbyopia (preoperative spherical equivalent range: -0.50 to 1.00 diopters). Efficacy was determined by measuring near and distance visual acuities and ocular aberrations, and satisfaction was assessed by a patient questionnaire...
July 2015: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/26084962/-bacterial-keratitis
#20
REVIEW
D Rachwalik, U Pleyer
Worldwide inflammatory corneal diseases are considered to be one of the leading causes of monocular blindness. Bacterial infectious are still predominant and are found in 80 % of patients with ulcerative keratitis. In recent years, both changes in risk conditions and changes in the bacterial spectrum can be observed. Contact lenses and refractive surgery are factors that have increased in importance according to some studies. Microorganisms especially Pseudomonas spp. and atypical mycobacteria are detectable in these patients...
June 2015: Klinische Monatsblätter Für Augenheilkunde
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