Read by QxMD icon Read

Ortho k

Natasha R Catlin, Cynthia J Willson, Matthew Stout, Grace E Kissling, Suramya Waidyanatha, Gregory L Baker, Barry K Hayden, Michael Wyde
ortho-Phthalaldehyde (OPA) is a high-level chemical disinfectant that is commonly used for chemical sterilization of dental and medical instruments as an alternative to glutaraldehyde, a known skin and respiratory sensitizer. Concern for safe levels of human exposure remains due to a lack of toxicity data as well as human case reports of skin and respiratory sensitization following OPA exposure. The present study evaluated the inhalational toxicity of OPA in Harlan Sprague-Dawley rats and B6C3F1/N mice. Groups of 10 male and female rats and mice were exposed to OPA by whole-body inhalation for 3 months at concentrations of 0 (control), 0...
October 17, 2017: Inhalation Toxicology
Jing Cao, Rachel Edwards, Janette Chairez, Sridevi Devaraj
BACKGROUND: Laboratory test in transport is a critical component of patient care, and capillary blood is a preferred sample type particularly in children. This study evaluated the performance of capillary blood testing on the epoc Point of Care Blood Analysis System (Alere Inc). METHODS: Ten fresh venous blood samples was tested on the epoc system under the capillary mode. Correlation with GEM 4000 (Instrumentation Laboratory) was examined for Na+, K+, Cl-, Ca2+, glucose, lactate, hematocrit, hemoglobin, pO2, pCO2, and pH, and correlation with serum tested on Vitros 5600 (Ortho Clinical Diagnostics) was examined for creatinine...
December 2017: Pract Lab Med
Santosh K Pagire, Asik Hossain, Lukas Traub, Sabine Kerres, Oliver Reiser
An efficient method for the synthesis of substituted cyclobutanes from cinnamates, chalcones, and styrenes has been developed utilizing a visible-light triplet sensitisation mode. This reaction provides a diverse range of substituted cyclobutanes in high yields under mild conditions without the need of external additives. Good regioselectivity is obtained due to strong π-π-stacking of arene moieties, whereas diastereoselectivity relies on the electronic effects or ortho-substitution of the arene substrate...
October 13, 2017: Chemical Communications: Chem Comm
Qinghui Kong, Jiang Guo, Jing Zhou, Yanling Zhang, Xiaoyan Dou
BACKGROUND: We aimed to identify factors influencing the therapeutic outcome of orthokeratology on controlling juvenile myopia progression, and the risk factors for complications. METHODS: Myopic patients (n=724) in Shenzhen Second Hospital from Jan 2011 to Jan 2016 fitted with orthokeratology lenses and followed-up for 6-65 months were reviewed retrospectively. Univariate and multivariate logistic regression analyses were used to screen for the factors that can improve treatment outcome and prevent the development of complications...
September 2017: Iranian Journal of Public Health
Tamiko Ikeno, Chihiro Miyashita, Sonomi Nakajima, Sumitaka Kobayashi, Keiko Yamazaki, Yasuaki Saijo, Toshiko Kita, Seiko Sasaki, Kanae Konishi, Junboku Kajiwara, Tsuguhide Hori, Reiko Kishi
BACKGROUND: Prenatal exposure to polychlorinated dibenzo-p-dioxins (PCDDs) or polychlorinated dibenzofurans (PCDFs) and dioxin-like polychlorinated biphenyls (dioxin-like compounds [DLCs]) through environmental chemicals may affect the neurodevelopment of children. In our previous study, an inverse association was observed between prenatal DLCs and neurodevelopment of infants aged 6months in both sexes. However, studies are yet to determine how long these adverse effects last. OBJECTIVE: To examine whether the effects of DLCs on cognitive development remains at 42months...
October 7, 2017: Science of the Total Environment
Naomasa Oka, Manabu Ishimaru, Masakazu Tane, Younes Sina, Carl J McHargue, Kurt E Sickafus, Eduardo Alves
Formation of metastable phases in Zr-ion-irradiated corundum alumina (Al2O3) upon thermal annealing was examined using transmission electron microscopy. A metastable cubic spinel phase was formed in the topmost layer of the as-irradiated microstructure. During thermal annealing at temperatures ranging from 1073 to 1273 K, this spinel layer grew in extent via an unusual corundum-to-spinel phase transformation. A normal spinel-to-corundum phase transformation was observed at post-irradiation annealing temperatures greater than 1473 K...
July 28, 2017: Microscopy
Johannes Landmann, Philipp T Hennig, Nikolai V Ignat'ev, Maik Finze
The potassium salt of the boron-centred nucleophile B(CN)3(2-) (1) readily reacts with perfluorinated arenes, such as hexafluorobenzene, decafluorobiphenyl, octafluoronaphthalene and pentafluoropyridine, which results in KF and the K(+) salts of the respective borate anions with one {B(CN)3} unit bonded to the (hetero)arene. An excess of K21 leads to the successive reaction of two or, in the case of perfluoropyridine, even three C-F moieties and the formation of di- and trianions, respectively. Moreover, all of the 11 partially fluorinated benzene derivatives, C6F6-n H n (n = 1-5), generally react with K21 to give new tricyano(phenyl)borate anions with high chemo- and regioselectivity...
September 1, 2017: Chemical Science
Lu Zhang, Yue Zhang, Yanlin Liu, Kai Wang, Mingwei Zhao
PURPOSE: To evaluate a novel fitting algorithm for estimation of alignment curve (AC) radius during orthokeratology lens trial. METHODS: Fifty myopic children were recruited in this study. AC radii were estimated by both traditional method using flat K readings and eccentricity values and by a novel fitting algorithm, which was composed of 256 circle fittings using corneal elevation data from the corresponding AC region and a succedent toric fitting based on these calculated AC curvatures...
October 4, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
Peter Coburger, Serhiy Demeshko, Christian Rödl, Evamarie Hey-Hawkins, Robert Wolf
The first homoleptic cobalt phosphanido complex [K(thf)4][Co{1,2-(PtBu2)2C2B10H12}2] (1) was prepared by an unprecedented oxidative P-P bond addition of an ortho-carborane-substituted 1,2-diphosphetane to cobalt(-I) in [K(thf)0.2][Co(η4-cod)2)] (cod = 1,5-cycloctadiene). Compound 1 is a rare distorted tetrahedral d6 complex with a low-spin ground state configuration. Magnetic measurements revealed that the complex is diamagnetic between 2 to 270 K in the solid state and at 298 K in THF d8 solution. Based on DFT calculations, the unusual singlet ground state is caused by the strong σ-donor and moderate π-donor properties of the bis(phosphanido) ligand...
October 5, 2017: Angewandte Chemie
Aurelija Mickevičiūtė, David D Timm, Marius Gedgaudas, Vaida Linkuvienė, Zhiwei Chen, Abdul Waheed, Vilma Michailovienė, Asta Zubrienė, Alexey Smirnov, Edita Čapkauskaitė, Lina Baranauskienė, Jelena Jachno, Jurgita Revuckienė, Elena Manakova, Saulius Gražulis, Jurgita Matulienė, Enrico Di Cera, William S Sly, Daumantas Matulis
Membrane-associated carbonic anhydrase (CA) isoform IV participates in carbon metabolism and pH homeostasis and is implicated in the development of eye diseases such as retinitis pigmentosa and glaucoma. A series of substituted benzenesulfonamides were designed and their binding affinity to CA IV was determined by fluorescent thermal shift assay and isothermal titration calorimetry (ITC). Compound [(4-chloro-2-phenylsulfanyl-5-sulfamoyl-benzoyl)amino]propyl acetate (19) bound CA IV with the K d of 1.0 nM and exhibited significant selectivity over the remaining 11 human CA isoforms...
October 3, 2017: European Biophysics Journal: EBJ
K D Croft, D Zhang, R Jiang, A Ayer, S Shengule, R J Payne, N C Ward, R Stocker
Population studies suggest cardiovascular health benefits of consuming fruits and vegetables rich in polyphenolic compounds such as flavonoids. We reported previously that the flavonoid quercetin protects arteries from oxidant-induced endothelial dysfunction and attenuates atherosclerosis in apolipoprotein E gene knockout mice, with induction of heme oxygenase-1 (Hmox1) playing a critical role. The present study investigated the structural requirements of flavonoids to induce Hmox1 in human aortic endothelial cells (HAEC)...
September 29, 2017: Free Radical Biology & Medicine
Zhouyue Li, Dongmei Cui, Yin Hu, Sichun Ao, Junwen Zeng, Xiao Yang
PURPOSE: To analyze the change in subfoveal choroidal thickness (SFChT) and its relationship with changes in axial length (AL) in myopic children treated with Orthokeratology (Ortho-k). METHODS: Fifty myopic children participated in this study: 29 subjects were treated with Ortho-k lenses and 21 with single vision distance spectacles. The SFChT and ocular biometrics, including AL, were measured at baseline, one month, and six months after lens wear in both groups...
September 18, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
Christopher S Frampton, David D MacNicol
The structure of the estrone-related steroid, Equilenin, C18H18O2 (systematic name 3-hy-droxy-13-methyl-11,12,13,14,15,16-hexa-hydro-cyclo-penta-[a]phen-anthren-17-one), has been determined at 100 K. The crystals are ortho-rhom-bic, P212121, and the absolute structure of the mol-ecule in the crystal has been determined by resonant scattering [Flack parameter = -0.05 (4)]. The C atoms of the A and B rings are almost coplanar, with an r.m.s. deviation from planarity of 0.0104 Å. The C ring has a sofa conformation, while the D ring has an envelope conformation with the methine C atom as the flap...
July 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
Farzaneh Nasrollahzadeh, Mehdi Varidi, Arash Koocheki, Farzin Hadizadeh
In present study, effect of conventional heating (CH) and microwave heating (MH) on Maillard reaction (MR) progression and structural, functional and antioxidant properties of glycated protein was investigated. The glycation process was carried out at 90°C, in bovine serum albumin-maltodextrin system. The extent of glycation was assessed by ortho-phthaldialdehyde and absorbance at 420nm. Afterwards, K-means clustering was applied to classify all treatments into three levels of glycation (low, medium, high)...
October 2017: Food Research International
S Ramachandraiah, K Sridharan, A Nishad, K K Manjusha, Esther A Abraham, M Mohamed Ramees
AIM: The aim of this study was to test the effect of varying alcohol concentrations of various commercially available mouth-washes on force decay of elastomeric chains in prestretched and unstretched condition. MATERIALS AND METHODS: A total of five specimen groups were tested with a total sample size of 180 specimens. A specimen is described as a three-link, short module, clear elastomeric chain (3M Unitek, Ortho Plus, Ortho Organizer). The control and test groups were independently submerged in separate 37°C artificial saliva to simulate the oral conditions...
September 1, 2017: Journal of Contemporary Dental Practice
László Valkai, Gábor Peintler, Attila K Horváth
Equilibria of periodate ion were reinvestigated in aqueous solution by using potentiometric titration, UV and Raman spectroscopies, and gravimetry simultaneously at 0.5 M ionic strength and at 25.0 ± 0.2 °C. Stepwise acid dissociation constants of orthoperiodic acid were found to be pK1 = 0.98 ± 0.18, pK2 = 7.42 ± 0.03, and pK3 = 10.99 ± 0.02, as well as pK2 = 7.55 ± 0.04 and pK3 = 11.25 ± 0.03 in the presence of sodium nitrate and sodium perchlorate as background salts, respectively. pK1 cannot be determined unambiguously from our experiments in the presence of sodium perchlorate...
August 31, 2017: Inorganic Chemistry
Leigh J Sowerby, Luke Rudmik
OBJECTIVE: Nasopharyngoscopes are an essential instrument to otolaryngologists; reprocessing them in a high-value manner is paramount. Although several different techniques for reprocessing exist, all methods yield similar effectiveness. Given equivalent effectiveness outcomes, a cost analysis of four nasopharyngoscope reprocessing techniques was performed. STUDY DESIGN: Cost-minimization analysis. METHODS: Four techniques were evaluated: 1) an automated reprocessor using peracetic acid (Steris System 1; Steris Canada Inc...
August 16, 2017: Laryngoscope
Lizhen Fang, Tyler G Saint-Denis, Buck L H Taylor, Seth Ahlquist, Kai Hong, SaiSai Liu, LiLi Han, K N Houk, Jin-Quan Yu
A conformationally flexible template for the meta-C-H olefination of benzoic acids was designed through both experimental and computational efforts. The newly designed template favors a silver-palladium heterodimer low barrier transition state, and demonstrates that it is feasible to lengthen templates so as to achieve meta-selectivity when the distance between the functional handle of the native substrate and target C-H bond decreases. Analysis of the ortho-, meta-, and para-C-H cleavage transition states determined that the new template conformation optimizes the interaction between the nitrile and palladium-silver dimer in the meta-transition state, enabling palladium to cleave meta-C-H bonds with moderate-to-good yields and generally high regioselectivity...
July 27, 2017: Journal of the American Chemical Society
Perruchon Chiara, Vasileiadis Sotirios, Rousidou Constantina, Papadopoulou S Evangelia, Tanou Georgia, Samiotaki Martina, Garagounis Constantinos, Molassiotis Athanassios, Papadopoulou K Kalliope, Karpouzas G Dimitrios
Ortho-phenylphenol (OPP) is a fungicide contained in agro-industrial effluents produced by fruit-packaging plants. Within the frame of developing bio-strategies to detoxify these effluents, an OPP-degrading Sphingomonas haloaromaticamans strain was isolated. Proteins/genes with a putative catabolic role and bacterium adaptation mechanisms during OPP degradation were identified via genomic and proteomic analysis. Transcription analysis of all putative catabolic genes established their role in the metabolism of OPP...
July 25, 2017: Scientific Reports
Zhi Chen, Feng Xue, Jiaqi Zhou, Xiaomei Qu, Xingtao Zhou
SIGNIFICANCE: Lens decentration is common and unavoidable to some extent during ortho-k treatment. By using a simplified method, we are able to predict the magnitude and direction of ortho-k lens decentration, which provides useful insights in screening for ideal ortho-k candidates and to make a quick decision when decentration happens. PURPOSE: The aim of this study was to investigate the influence of corneal elevation asymmetry on ortho-k lens decentration. METHODS: Thirty-six eyes of 36 subjects were fitted with four-curve reverse geometry ortho-k contact lenses...
September 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"