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Myopia control

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https://www.readbyqxmd.com/read/29146755/ocular-findings-in-loeys-dietz-syndrome
#1
Catharina Busch, Robert Voitl, Barbara Goergen, Tomasz Zemojtel, Petra Gehle, Daniel J Salchow
BACKGROUND: Loeys-Dietz syndrome (LDS), an autosomal-dominant connective tissue disorder, is characterised by systemic manifestations including arterial aneurysm and craniofacial dysmorphologies. Although ocular involvement in LDS has been reported, detailed information on those manifestations is lacking. METHODS: Retrospective chart review of patients with diagnosed LDS and comparison with age-matched control patients. RESULTS: Mean age was 37...
November 16, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29137074/refractive-state-and-optical-compositions-of-preterm-children-with-and-without-retinopathy-of-prematurity-in-the-first-6-years-of-life
#2
Xiaohui Zhu, Rulian Zhao, Yang Wang, Lijuan Ouyang, Jing Yang, Yong Li, Lianhong Pi
This study aimed to investigate the refractive state and optical compositions of preterm children with and without mild retinopathy of prematurity (ROP) and explore the influence of prematurity and mild ROP on the development of refractive state and optical compositions.Preterm children who received fundus screening were recruited, and divided into ROP group and non-ROP group. Term children matched in age were also recruited as controls. Several correspondence indicators were measured before and after ciliary muscle paralysis with 1% cyclopentanone...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29135319/crosslinking-enzyme-lysyl-oxidase-modulates-scleral-remodeling-in-form-deprivation-myopia
#3
Ying Yuan, Min Li, Qingzhong Chen, Rao Me, Yunjie Yu, Qing Gu, Guangsen Shi, Bilian Ke
PURPOSE: Scleral remodeling causes the excessive ocular elongation that underlies myopia. Lysyl oxidase (LOX), a copper-containing amine oxidase, can catalyze collagen and elastin crosslinking. The purpose of this study was to investigate the role of LOX in scleral remodeling in form-deprivation myopia (FDM). METHODS: Seventy-five guinea pigs were randomly divided into five groups as follows: a normal control group, an FDM group, an FDM plus β-aminopropionitrile (BAPN) group, an FDM plus TGF-β1 (TGF-β1) group, and an FDM plus vehicle group...
November 14, 2017: Current Eye Research
https://www.readbyqxmd.com/read/29117415/risk-factors-for-opaque-bubble-layer-in-small-incision-lenticule-extraction-smile
#4
Liuyang Li, Julie M Schallhorn, Jiaonan Ma, Lin Zhang, Rui Dou, Yan Wang
PURPOSE: To assess the independent effect of myopia and astigmatism on the risk of the occurrence of opaque bubble layer (OBL) in small incision lenticule extraction (SMILE) and further investigate the relationship between scanning depth and OBL. METHODS: Twenty-two cases and 317 controls were included in a case-control study from the database of Tianjin Eye Hospital from April 2015 to July 2016. Baseline characteristics were recorded and all of the eyes were manually reviewed by two different observers masked to preoperative refractive status...
November 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/29116952/a-model-of-the-effect-of-lens-development-on-refraction-in-schoolchildren
#5
Ji C He
SIGNIFICANCE: The study provides a new theory on the mechanism underlying myopia development, and it could be useful in clinical practice to control myopia development in schoolchildren. PURPOSE: To model the effect of the crystalline lens on refractive development in schoolchildren. METHODS: The Zemax 13 was used to calculate Zernike aberrations and refractions across 50° horizontal visual fields. Optical effects of the anterior chamber depth, lens thickness, and radii of curvature of the lens surfaces on refractions were modeled...
November 8, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/29109514/violet-light-transmission-is-related-to-myopia-progression-in-adult-high-myopia
#6
Hidemasa Torii, Kazuhiko Ohnuma, Toshihide Kurihara, Kazuo Tsubota, Kazuno Negishi
Myopia is increasing worldwide. Although the exact etiology of myopia is unknown, outdoor activity is one of the most important environmental factors for myopia control. We previously reported that violet light (VL, 360-400 nm wavelength), which is abundant in the outdoor environment, suppressed myopia progression for individuals under 20 years of age. However, whether VL is also effective for adult high myopia, which can be sight-threatening, has remained unknown. To investigate the influence of VL for adult myopia, we retrospectively compared the myopic progression and the axial length elongation over five years in adult high myopic patients over 25 years of age after two types (non-VL transmitting and VL transmitting) of phakic intraocular lens (pIOL) implantation...
November 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29099498/clinical-spectrum-and-surgical-outcomes-in-spherophakia-a-prospective-interventional-study
#7
S Khokhar, G Pillay, S Sen, E Agarwal
PurposeTo study the varied clinical presentations of patients with spherophakia, their management using surgical methods, and the clinical outcomes.Patients and methodsA prospective interventional study of 13 patients of spherophakia who presented to us from January 2014 and were followed up over the course of their treatment, and the data were documented for analysis.ResultsIn all, 26 eyes of 13 patients were reviewed and the median age of presentation was 12±12.05 years. All patients had a bilateral presentation with 22 eyes having lenticular myopia with a mean refractive error of -11...
November 3, 2017: Eye
https://www.readbyqxmd.com/read/29063473/comparing-aspheric-ablation-profile-with-standard-corneal-ablation-for-correction-of-myopia-and-myopic-astigmatism-a-contralateral-eye-study
#8
Mohammad Ghoreishi, Afsaneh Naderi Beni, Zahra Naderi Beni, Alireza Zandi, Farzan Kianersi
The purpose of this study is to compare visual outcomes of myopic refractive surgery, using tissue saving (TS), a standard ablation profile by a Technolas 217z100, and aberration smart ablation (ASA), an aspheric algorithm by a MEL 80 excimer laser in two eyes of one patient. In this prospective interventional paired-eye controlled study, a total of 100 eyes of 50 participants with myopia with or without astigmatism underwent thin-flap Femto-LASIK, using a Femto LDV femtosecond laser (Ziemer Ophthalmic Systems AG, Port, Switzerland)...
December 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29062769/the-association-of-lumican-polymorphisms-and-high-myopia-in-a-southern-chinese-population
#9
Gui-Fang Wang, Qing-Shan Ji, Bing Qi, Guo-Cheng Yu, Lian Liu, Jing-Xiang Zhong
AIM: To investigate the correlation between lumican (LUM) gene and high myopia in a Southern Chinese population. METHODS: The study comprised of 95 high myopia patients with a spherical equivalent ≤-6.5 diopters (D). The control group recruited 95 individuals with a spherical equivalent ranging from -0.5 D to +0.5 D. Direct sequencing was used to detect the single nucleotide polymorphisms (SNPs) of LUM gene in coding region. Genotype distributions were tested for Hardy-Weinberg disequilibrium...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29057641/anti-vascular-endothelial-growth-factor-therapy-for-myopic-choroidal-neovascularization
#10
Danny S C Ng, Timothy Y Y Lai, Chui Ming Gemmy Cheung, Kyoko Ohno-Matsui
Myopic choroidal neovascularization (CNV) is one of the most vision-impairing complications in patients with pathologic myopia. It is also one of the most frequently encountered non‒age-related macular degeneration causes of CNV and affects young patients in the working age group. Fluorescein angiography (FA) and spectral domain optical coherence tomography (OCT) are generally indicated to confirm the diagnosis of active myopic CNV before initiation of treatment. Without treatment, natural history studies have shown that the vision outcome can be very poor...
October 20, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/29053555/case-series-analysis-of-myopic-progression-control-with-a-unique-extended-depth-of-focus-multifocal-contact-lens
#11
Jeffrey Cooper, Brett OʼConnor, Ronald Watanabe, Randall Fuerst, Sharon Berger, Nadine Eisenberg, Sally M Dillehay
OBJECTIVES: To determine the rate of myopia progression in children fit with a commercially available extended depth of focus (center distance) multifocal soft contact lens with attributes theoretically expected to slow the progression of myopia. METHODS: A retrospective case series analysis of 32 patients (ages 6-19 years, mean 10.98±2.95) from 10 practice locations was performed. At initial presentation, 44% wore spectacles, 37.5% spherical soft contact lenses, 15...
October 19, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/29053487/effect-of-experimental-conditions-in-the-accommodation-response-in-myopia
#12
Carles Otero, Mikel Aldaba, Fuensanta A Vera-Diaz, Jaume Pujol
SIGNIFICANCE: The accommodative response is more affected by the type of refractive error than the method of stimulation, field of view (FOV), or stimulus depth. PURPOSE: This study aims to analyze the effect of stimulation method, stimulus depth, and FOV on the accommodation response (AR) for emmetropes (EMM), late-onset myopes (LOM), and early-onset myopes (EOM). METHODS: Monocular AR was measured in 26 young observers (n = 9 EMM, n = 8 LOM, n = 9 EOM) under 60 different viewing conditions that were the result of permuting the following factors: (1) stimulation method (free space or Badal lens viewing), (2) stimulus depth (flat or volumetric), (3) FOV (2...
October 19, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/29044055/assessment-of-bicc-family-rna-binding-protein-1-and-ras-protein-specific-guanine-nucleotide-releasing-factor-1-as-candidate-genes-for-high-myopia-a-case-control-study
#13
Li Hepei, Xie Mingkun, Wang Li, Wu Jin
PURPOSE: The aim is to evaluate the association between high myopia and genetic variant in the BicC family RNA binding protein 1 (BICC1) as well as its association with Ras protein specific guanine nucleotide releasing factor 1 (RASGRF1) genes in a Chinese Han population with a case-control study. METHODS: Five TagSNPs in BICC1 and RASGRF1 genes were selected and genotyped in 821 unrelated subjects, which composed of 419 controls (spherical equivalent within ±1...
October 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29034154/intraocular-pressure-monitoring-by-rebound-tonometry-in-children-with-myopia
#14
Jenchieh Weng, I-Lun Tsai, Li-Lin Kuo, Ching-Yao Tsai, Lin-Chung Woung, Ya-Chuan Hsiao
BACKGROUND/PURPOSE: Topical atropine treatment is generally accepted to retard the progression of myopia, but it is associated with side effects such as photophobia and elevation of intraocular pressure (IOP). IOP measurements in children are challenging. The traditional applanation tonometry by direct contact with the cornea will require patient's cooperation. The rebound tonometer, using a dynamic electromechanical method for measuring IOP, shows good correlation with traditional tonometry...
July 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29032414/influence-of-lasek-on-schi%C3%A3-tz-goldmann-and-dynamic-contour-tonometry
#15
Marco Sales-Sanz, Esther Arranz-Marquez, Carolina Arruabarrena, Miguel A Teus
PURPOSE: Our purpose was to assess the effect of LASEK surgery on ocular rigidity and to compare its effect on intraocular pressure (IOP) readings with Goldmann applanation tonometry (GAT), Schiøtz indentation tonometry (ST) and dynamic contour tonometry (DCT). METHODS: Prospective, observational, single-masked cohort study. One eye per patient from 31 consecutive subjects who underwent LASEK refractive surgery to correct myopia, as well as from 108 non-operated myopic patients, were included...
October 14, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29030016/does-a-two-year-period-of-orthokeratology-lead-to-changes-in-the-endothelial-morphology-of-children
#16
Sin Wan Cheung, Pauline Cho
PURPOSE: To compare changes in endothelial morphology in the central and superior cornea in subjects wearing single-vision spectacles and orthokeratology lenses over two years. METHODS: Endothelial images of the two locations of 99 subjects (6-12 years) from completed myopia control studies were analysed. Endothelial cell density (ECD), coefficient of variation in cell size (CV), and hexagonality (HEX) before and two years after treatment were compared between the two groups of subjects...
October 10, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29026787/factors-determining-effective-orthokeratology-treatment-for-controlling-juvenile-myopia-progression
#17
Qinghui Kong, Jiang Guo, Jing Zhou, Yanling Zhang, Xiaoyan Dou
BACKGROUND: We aimed to identify factors influencing the therapeutic outcome of orthokeratology on controlling juvenile myopia progression, and the risk factors for complications. METHODS: Myopic patients (n=724) in Shenzhen Second Hospital from Jan 2011 to Jan 2016 fitted with orthokeratology lenses and followed-up for 6-65 months were reviewed retrospectively. Univariate and multivariate logistic regression analyses were used to screen for the factors that can improve treatment outcome and prevent the development of complications...
September 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/29018754/how-to-effectively-manage-myopia
#18
Ann Yi-Chiun Chuang
Myopia has become epidemic in the world. Without effective control, the progression may lead to excessive myopia with severe complications affecting vision and ocular alignment. The genetic factors and environmental factors of myopia are closely interrelated to each other. Asian ethnicity and parental myopia, among other genetic factors, influence the refractive outcome dramatically when environmental risk factors such as hours of near work and reading distance are analyzed. Outdoor activities are protective measures that retard myopia progression...
January 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/28975669/refractive-error-in-chinese-with-type-2-diabetes-and-its-association-with-glycaemic-control
#19
E Song, Deng-Juan Qian, Shan Wang, Cailian Xu, Chen-Wei Pan
BACKGROUND: The aim of this study was to determine the prevalence of refractive errors and their association with glycaemic control among adults with type 2 diabetes mellitus (T2DM) in eastern China. METHODS: A community-based survey, including 913 adults with T2DM aged 30 to 89 years, was conducted. Refractive error was assessed by autorefraction, after which subjective refraction was performed. Ocular biometric parameters were measured by non-contact partial coherence laser interferometry...
October 3, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28966549/myopia-induced-by-flickering-light-in-guinea-pig-eyes-is-associated-with-increased-rather-than-decreased-dopamine-release
#20
Xiumei Luo, Bing Li, Tao Li, Yue Di, Changyue Zheng, Shunmei Ji, Yuanyuan Ma, Jie Zhu, Xuefeng Chen, Xiaodong Zhou
PURPOSE: It is well known that the dopaminergic signaling pathway plays a pivotal role in the control of axial elongation. Much research has shown that retinal dopamine (DA) is decreased in experimental myopia, but the exact alteration in DA quantity underlying the myopia model induced by flickering light (FL) has not yet been fully elucidated. Therefore, in this study, we first attempted to prove the feasibility of the myopia model induced by FL and then to determine whether and how DA and its receptors changed in myopia induced by FL...
2017: Molecular Vision
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