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Trajectory of illness

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https://www.readbyqxmd.com/read/29474321/evaluation-of-icu-risk-models-adapted-for-use-as-continuous-markers-of-severity-of-illness-throughout-the-icu-stay
#1
Omar Badawi, Xinggang Liu, Erkan Hassan, Pamela J Amelung, Sunil Swami
OBJECTIVES: Evaluate the accuracy of different ICU risk models repurposed as continuous markers of severity of illness. DESIGN: Nonintervention cohort study. SETTING: eICU Research Institute ICUs using tele-ICU software calculating continuous ICU Discharge Readiness Scores between January 2013 and March 2016. PATIENTS: Five hundred sixty-one thousand four hundred seventy-eight adult ICU patients with an ICU length of stay between 4 hours and 30 days...
March 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29474102/defining-the-elements-of-early-palliative-care-that-are-associated-with-patient-reported-outcomes-and-the-delivery-of-end-of-life-care
#2
Michael Hoerger, Joseph A Greer, Vicki A Jackson, Elyse R Park, William F Pirl, Areej El-Jawahri, Emily R Gallagher, Teresa Hagan, Juliet Jacobsen, Laura M Perry, Jennifer S Temel
Purpose We describe the key elements of early palliative care (PC) across the illness trajectory and examine whether visit content was associated with patient-reported outcomes and end-of-life care. Methods We performed a secondary analysis of patients with newly diagnosed advanced lung or noncolorectal GI cancer (N = 171) who were randomly assigned to receive early PC. Participants attended at least monthly visits with board-certified PC physicians and advanced practice nurses at Massachusetts General Hospital...
February 23, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29468344/co-development-of-problem-gambling-and-depression-symptoms-in-emerging-adults-a-parallel-process-latent-class-growth-model
#3
Jason D Edgerton, Matthew T Keough, Lance W Roberts
This study examines whether there are multiple joint trajectories of depression and problem gambling co-development in a sample of emerging adults. Data were from the Manitoba Longitudinal Study of Young Adults (n = 679), which was collected in 4 waves across 5 years (age 18-20 at baseline). Parallel process latent class growth modeling was used to identified 5 joint trajectory classes: low decreasing gambling, low increasing depression (81%); low stable gambling, moderate decreasing depression (9%); low stable gambling, high decreasing depression (5%); low stable gambling, moderate stable depression (3%); moderate stable problem gambling, no depression (2%)...
February 21, 2018: Journal of Gambling Studies
https://www.readbyqxmd.com/read/29466377/understanding-the-psychiatric-effects-of-concussion-on-constructed-identity-in-hockey-players-implications-for-health-professionals
#4
Ryan Todd, Shree Bhalerao, Michael T Vu, Sophie Soklaridis, Michael D Cusimano
OBJECTIVE: The following study was undertaken to investigate the effect of concussion and psychiatric illness on athletes and their caregivers. METHODS: Semi-structured interviews with 20 ice hockey stakeholders (17 men and 3 women) including minor and professional players, coaches, parents, and physicians were conducted over two years (2012-2014). These interviews were analyzed using grounded theory. RESULTS: From this analysis, a common biographical theme emerged whereby the subject's identity as a hockey player, constructed early in life over many years, was disrupted by concussion...
2018: PloS One
https://www.readbyqxmd.com/read/29464973/trajectories-of-episodic-disability-in-people-aging-with-hiv-a-longitudinal-qualitative-study
#5
Patricia Solomon, Kelly Kathleen O'Brien, Stephanie Nixon, Lori Letts, Larry Baxter, Nicole Gervais
People living with HIV may experience disability which is episodic in nature, characterized by periods of wellness and illness. The purpose of this longitudinal qualitative study was to understand how the episodic nature of HIV and the associated uncertainty shape the disability experience of older adults living with HIV over time. Fourteen men and 10 women who were HIV positive and over 50 years (mean age: 57 years; range: 50-73) participated in 4 interviews over 20 months. Longitudinal analyses of the transcribed interviews identified 4 phenotypes of episodic disability over time: decreasing, increasing, stable, or significant fluctuations...
January 2018: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/29464226/depression-in-children
#6
Julian Charles, Mandana Fazeli
BACKGROUND: Major depressive disorder (MDD) in children (5-12 years of age) is a confronting and serious psychiatric illness. MDD has significant ramifications for the psychosocial development of the child, yet it remains under-recognised and undertreated. General practice is where these children and their parents will first present. OBJECTIVE: The aim of this article is to provide general practitioners (GPs) with a framework for considering MDD in a child and recommendations for treatment...
December 2017: Australian Family Physician
https://www.readbyqxmd.com/read/29463062/palliative-care-for-children-in-hospital-essential-roles
#7
REVIEW
Ross Drake
Palliative care for children in pediatric hospitals is a vital part of the network of services supporting children with severe illness. This has been recognized, with a trend over the past decade for an increased number of pediatric palliative care (PPC) services established in pediatric hospitals. The inpatient team is in the unique position of influencing the early identification of children and their families, across the age and diagnostic spectrum, which could benefit from palliative care. These services have an opportunity to influence the integration of the palliative approach throughout the hospital, and in so doing, have the capacity to improve many aspects of care, including altering an increasingly futile and burdensome treatment trajectory, and ensuring improved symptom (physical and psychological) management...
February 19, 2018: Children
https://www.readbyqxmd.com/read/29453748/social-distance-in-lithuanian-psychology-and-social-work-students-and-professionals
#8
Aiste Pranckeviciene, Kristina Zardeckaite-Matulaitiene, Rasa Marksaityte, Aukse Endriulaitiene, Douglas R Tillman, David D Hof
PURPOSE: This cross-sectional study aimed to compare desire for social distance from people with mental illness in the disciplines of social work and psychology, and among students and professionals having different professional experience. METHODS: 948 respondents (715 students and 233 professionals) from Lithuanian educational and mental health-care institutions participated in an anonymous survey. Social distance was measured using Lithuanian Social Distance Scale which was created for this study...
February 16, 2018: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/29451933/depressive-symptoms-and-physical-frailty-in-older-adults-with-chronic-heart-failure-a-cross-sectional-study
#9
Youn-Jung Son, Eun Ji Seo
Depressive symptoms and physical frailty have been reported to be predictive of adverse outcomes in individuals with heart failure (HF). Depressive symptoms could be a predisposing factor of physical frailty in older adults. Despite the high prevalence of HF, few studies on the relationship between these two factors have been performed in older adults with HF. To identify the relationship between depressive symptoms and physical frailty in HF, 190 older adults with HF were recruited from an outpatient clinic at a tertiary hospital in South Korea...
February 13, 2018: Research in Gerontological Nursing
https://www.readbyqxmd.com/read/29451672/predictors-of-persistent-prescription-opioid-analgesic-use-among-people-without-cancer-in-australia
#10
Samanta Lalic, Natasa Gisev, J Simon Bell, Maarit Jaana Korhonen, Jenni Ilomäki
AIMS: To identify patterns of opioid analgesic use and determine predictors of persistent opioid use among people without cancer. METHODS: A population-based cohort study of Australians initiating prescription opioids from July 2013 to December 2015 was conducted using data from a random 10% sample of people who accessed medicines through Australia's Pharmaceutical Benefits Scheme. A 12-month look-back period was used to define opioid initiation, exclude people with cancer, and determine comorbidities...
February 16, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29425726/does-poor-fetal-growth-influence-the-extent-of-fetal-exposure-to-maternal-medications
#11
REVIEW
Jia Yin Soo, Michael D Wiese, Mary J Berry, Janna L Morrison
A large proportion of women are prescribed a medication during pregnancy, and the conditions requiring treatment with these medicines are often also associated with placental dysfunction and abnormal fetal growth. For the fetus, exposure to maternal illness or medications can alter fetal growth trajectory, which is a key indicator of fetal and postnatal wellbeing. There is a large amount of human and animal evidence highlighting the hormonal and/or metabolic changes that occur in both the mother and the fetus as a result of maternal illness or either excessive or restricted fetal growth...
February 6, 2018: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/29425060/measuring-development-of-adolescent-and-young-adult-cancer-patients-an-integrative-review-of-available-instruments
#12
Cynthia J Bell, Ryan A Bell, Brad Zebrack, Ikuko Kato, Alyssa Morse, Scott C Borinstein
Adolescents and young adults (AYAs) 15-39 years old face unique challenges during cancer treatment as developmental and social needs are often disrupted to achieve cure. Developmentally appropriate supportive care for AYAs across the cancer trajectory is needed. The purpose of this review is to identify and describe instruments that measure AYA development across physical, psychological, and social domains, commenting on the instruments' psychometric properties and usefulness in clinical practice and research...
February 9, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29423678/quality-of-life-trajectories-during-the-first-year-following-hematopoietic-cell-transplantation-an-inception-cohort-study
#13
Gerald M Devins, Kenneth Mah, Hans A Messner, Anargyros Xenocostas, Lise Gauvin, Jeffrey H Lipton
BACKGROUND: Allogeneic hematopoietic cell transplantation (HCT) affects quality of life (QOL). Patient-reported outcomes examine symptoms, side effects, distress, and physical and social problems, but positive outcomes have been ignored. This inception cohort study followed people over the first year following HCT to document positive and negative outcomes. METHODS: People with hematologic cancers treated by HCT completed complementary self-report instruments at four milestones: (a) pre-transplant (N = 88); (b) engraftment (N = 80); (c) short-term post-discharge (N = 60); and (d) long-term post-discharge (N = 45)...
February 8, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29414028/relation-of-long-term-patterns-in-caregiving-activity-and-depressive-symptoms-to-telomere-length-in-older-women
#14
Shun-Chiao Chang, Marta Crous-Bou, Jennifer Prescott, Bernard Rosner, Naomi M Simon, Wei Wang, Immaculata De Vivo, Olivia I Okereke
BACKGROUND: Research links psychological stress to accelerated cellular aging. Here we examined whether long-term patterns of depression and caregiving burden, forms of chronic psychological stress, were associated with shorter telomere length, a biomarker of cellular aging. METHODS: The study included 1250 healthy older women (mean: 68.0; range: 60-81 years) in the Nurses' Health Study. Long-term patterns in depressive symptoms and caregiving activity (separated into care of children/grandchildren vs...
January 9, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29412396/-the-death-of-ivan-ilyich-and-multiple-dimensions-of-illness
#15
Paulo Cesar Alves
The short story "The Death of Ivan Ilyich" (1886), Leo Tolstoy (1828-1910) provides key elements for a reflection on the meaning of long-term illness. Based on Tolstoy's short story the present paper analyzes the multiple dimensions of the process of illness. It starts with the argument that illness is not an a priori totality, but a trajectory of associations between the sick person, the doctor, family members, friends and caregivers. Acting, being affected, thinking and feeling all come together in the development of these associations...
February 2018: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/29412394/biographical-ruptures-and-flows-in-the-family-experience-and-trajectory-of-children-with-cystic-fibrosis
#16
Marcelo Eduardo Pfeiffer Castellanos, Nelson Filice de Barros, Sandra Straccialano Coelho
Biographical disruption (BD) became a core concept of sociological studies on the chronic illness experience by showing how this event can be strongly affected by ruptures in the ways of living and organizing the biographical trajectory through narratives. Critical reviews have pointed out that the widespread use of this concept was not sufficiently attentive to its analytical limits, e.g. addressing experiences of children with genetic diseases, when biographic flows (BF) rather than BD would be probably found...
February 2018: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/29406379/conceptualizing-post-intensive-care-syndrome-in-children-the-pics-p-framework
#17
Joseph C Manning, Neethi P Pinto, Janet E Rennick, Gillian Colville, Martha A Q Curley
CONTEXT: Over the past several decades, advances in pediatric critical care have saved many lives. As such, contemporary care has broadened its focus to also include minimizing morbidity. Post Intensive Care Syndrome, also known as "PICS," is a group of cognitive, physical, and mental health impairments that commonly occur in patients after ICU discharge. Post Intensive Care Syndrome has been well-conceptualized in the adult population but not in children. OBJECTIVE: To develop a conceptual framework describing Post Intensive Care Syndrome in pediatrics that includes aspects of the experience that are unique to children and their families...
February 5, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29402375/neuroanatomical-phenotypes-in-mental-illness-identifying-convergent-and-divergent-cortical-phenotypes-across-autism-adhd-and-schizophrenia
#18
Min Tae M Park, Armin Raznahan, Philip Shaw, Nitin Gogtay, Jason P Lerch, M Mallar Chakravarty
BACKGROUND: There is evidence suggesting neuropsychiatric disorders share genomic, cognitive and clinical features. Here, we ask if autism-spectrum disorders (ASD), attention-deficit/hyperactivity disorder (ADHD) and schizophrenia share neuroanatomical variations. METHODS: First, we used measures of cortical anatomy to estimate spatial overlap of neuroanatomical variation using univariate methods. Next, we developed a novel methodology to determine whether cortical deficits specifically target or are "enriched" within functional resting-state networks...
February 5, 2018: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/29396310/parent-s-perspectives-on-how-they-cope-with-the-impact-on-their-family-of-a-child-with-heart-disease
#19
Alun C Jackson, Rosemary O Higgins, Erica Frydenberg, Rachel P-T Liang, Barbara M Murphy
PURPOSE: Studies of familial coping with a child's chronic condition have highlighted psychological distress; family functioning; and quality of life; as issues that demand coping strategies. There are conflicting findings on impact and coping and a paucity of information about the specific coping challenges for parents of a child with heart disease, with few qualitative studies in this area. The purpose of the study was to explore the way parents coped with their child's heart condition as it impacted on different domains of family functioning...
January 31, 2018: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29395604/patterns-and-predictors-of-trajectories-for-social-and-occupational-functioning-in-patients-presenting-with-first-episode-non-affective-psychosis-a-three-year-follow-up-study
#20
Wing Chung Chang, Angel On Ki Chu, Vivian Wing Yan Kwong, Corine Sau Man Wong, Christy Lai Ming Hui, Sherry Kit Wa Chan, Edwin Ho Ming Lee, Eric Yu Hai Chen
BACKGROUND: Functional impairment is prevalent in patients with first-episode psychosis (FEP). Longitudinal course of functioning in the early stage of psychotic illness is under-studied. In this report, we aimed to investigate the patterns and baseline predictors of social-occupational functional trajectories over 3 years, utilizing growth mixture modeling (GMM) analysis, in a large representative Chinese young FEP cohort in Hong Kong. METHOD: Six hundred seventeen consecutive patients aged 15-25 years presenting with first-episode non-affective psychosis to a specialized early intervention service were studied...
January 27, 2018: Schizophrenia Research
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