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Trajectory of illness

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https://www.readbyqxmd.com/read/28441882/work-right-to-right-work-an-automythology-of-chronic-illness-and-work
#1
Lavanya Vijayasingham
Objectives Chronic illness is known to disrupt and redirect the usual course of work trajectories. This article aims to portray the longitudinal course of negotiating work after multiple sclerosis. Methods Using therapy and personal journals to reconstruct memories and experience, an autoethnography is produced and narrated within Campbell's "Hero's Journey" automythology framework. Results The narrative highlights the intrasubjectivity of illness meaning-the changing internal meaning-making and external behavior and decision-making dynamics...
January 1, 2017: Chronic Illness
https://www.readbyqxmd.com/read/28440047/mental-illness-in-bariatric-surgery-a-cohort-study-from-the-portal-network
#2
David Fisher, Karen J Coleman, David E Arterburn, Heidi Fischer, Ayae Yamamoto, Deborah R Young, Nancy E Sherwood, Connie Mah Trinacty, Kristina H Lewis
OBJECTIVE: To compare bariatric surgery outcomes according to preoperative mental illness category. METHODS: Electronic health record data from several US healthcare systems were used to compare outcomes of four groups of patients who underwent bariatric surgery in 2012 and 2013. These included the following: people with (1) no mental illness, (2) mild-to-moderate depression or anxiety, (3) severe depression or anxiety, and (4) bipolar, psychosis, or schizophrenia spectrum disorders...
May 2017: Obesity
https://www.readbyqxmd.com/read/28428892/a-comparison-of-earlier-and-enhanced-rehabilitation-of-mechanically-ventilated-patients-in-critical-care-compared-to-standard-care-rehab-study-protocol-for-a-single-site-randomised-controlled-feasibility-trial
#3
Catherine Snelson, Charlotte Jones, Gemma Atkins, James Hodson, Tony Whitehouse, Tonny Veenith, David Thickett, Emma Reeves, Aisling McLaughlin, Lauren Cooper, David McWilliams
BACKGROUND: Mortality from critical illness is improving, but survivors suffer from prolonged weakness and psychological and cognitive impairments. Maximising the recovery after critical illness has been highlighted as a research priority, especially in relation to an ageing population who present with higher rates of pre-morbid disability. Small studies have shown that starting rehabilitation early within the intensive care unit (ICU) improves short-term outcomes. Systematic reviews have highlighted the need for robust multicentre randomised controlled trials with longer term follow-up...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28420297/the-social-trajectory-of-brain-tumor-a-qualitative-metasynthesis
#4
Lee Cubis, Tamara Ownsworth, Mark B Pinkham, Suzanne Chambers
PURPOSE: Research indicates that strong social ties can buffer the adverse effects of chronic illness on psychological well-being. Brain tumor typically leads to serious functional impairments that affect relationships and reduce social participation. This metasynthesis aimed to identify, appraise and integrate the findings of qualitative studies that reveal the impact of brain tumor on social networks. METHODS: Four major databases (PubMed, CINAHL, Cochrane Library and PsycINFO) were systematically searched from inception to September 2016 for qualitative studies that reported findings on the impact of primary brain tumor on social networks during adulthood...
April 19, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28420191/designing-effective-interactions-for-concordance-around-end-of-life-care-decisions-lessons-from-hospice-admission-nurses
#5
Carey Candrian, Channing Tate, Kirsten Broadfoot, Alexandra Tsantes, Daniel Matlock, Jean Kutner
Near the end of life, hospice care reduces symptom-related distress and hospitalizations while improving caregiving outcomes. However, it takes time for a person to gain a sufficient understanding of hospice and decide to enroll. This decision is influenced by knowledge of hospice and its services, emotion and fear, cultural and religious beliefs, and an individual's acceptance of diagnosis. Hospice admission interactions, a key influence in shaping decisions regarding hospice care, happen particularly late in the illness trajectory and are often complex, unpredictable, and highly variable...
April 18, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/28415870/longitudinal-changes-in-the-antecedent-and-early-manifest-course-of-bipolar-disorder-a-narrative-review-of-prospective-studies
#6
Andrea Pfennig, Karolina Leopold, Philipp Ritter, Anne Böhme, Emanuel Severus, Michael Bauer
OBJECTIVE: Prospective study designs ideally allow patients to be followed from the first manifestations of the illness or even from an at-risk stage. It can thus provide data on the predictive value of changes in clinical symptomatology, cognition or further biological markers to broaden our understanding of the etiopathology and symptomatic trajectory of bipolar disorders. The scope of this narrative review is to summarize evidence from prospectively collected data on psychopathological and other clinical and biological changes in the early developmental course of bipolar disorders...
May 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/28410981/predicting-healthcare-trajectories-from-medical-records-a-deep-learning-approach
#7
Trang Pham, Truyen Tran, Dinh Phung, Svetha Venkatesh
Personalized predictive medicine necessitates the modeling of patient illness and care processes, which inherently have long-term temporal dependencies. Healthcare observations, stored in electronic medical records are episodic and irregular in time. We introduce DeepCare, an end-to-end deep dynamic neural network that reads medical records, stores previous illness history, infers current illness states and predicts future medical outcomes. At the data level, DeepCare represents care episodes as vectors and models patient health state trajectories by the memory of historical records...
April 11, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28409715/an-open-effectiveness-trial-of-a-multimodal-inpatient-treatment-for-depression-and-anxiety-among-adults-with-serious-mental-illness
#8
J Christopher Fowler, Joshua D Clapp, Alok Madan, Jon G Allen, B Christopher Frueh, John M Oldham
OBJECTIVE: This prospective open effectiveness trial examined symptom change trajectories and rates of remission from depression and anxiety in an intensive multimodal inpatient treatment for adults with serious mental illness (SMI). Patient baseline characteristics were examined as mediators/moderators of treatment response. METHODS: Adult inpatients with SMI (N = 994) completed an average of 39 days of inpatient treatment. Latent growth curve (LGC) methods were used to model symptom trajectories, estimating expected remission based on individual patterns of change observed across the sample...
2017: Psychiatry
https://www.readbyqxmd.com/read/28399317/patterns-of-new-physical-problems-emerging-in-long-term-care-residents-with-dementia
#9
Christine R Kovach, Julie Ellis, Crystal-Rae Evans
Individuals receiving skilled nursing care have multiple comorbid conditions that impact comfort and resource use. The current study describes variations in the trajectories of new physical problems emerging over 8 weeks and the predictive value for future health and behavior in a sample of 72 residents with dementia. Residents had two to 37 new physical problems occurring over 8 weeks. Sixty-five percent of the sample had five or more new problems and were identified by three unstable trajectories. Common problems, illnesses, and symptoms accounted for 28...
April 11, 2017: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/28399022/palliative-and-end-of-life-care-in-nephrology-moving-from-observations-to-interventions
#10
Nwamaka D Eneanya, Michael K Paasche-Orlow, Angelo Volandes
PURPOSE OF REVIEW: In comparison with patients who have other serious illnesses, patients with advanced kidney disease have a higher rate of intensive care utilization at the end of life and receive palliative care less frequently. Consensus and clinical practice guidelines have therefore recommended the incorporation of palliative care earlier in the disease trajectory. This review summarizes recent literature on this aspect of care and will highlight future directions for patient-centered care within palliative nephrology...
April 8, 2017: Current Opinion in Nephrology and Hypertension
https://www.readbyqxmd.com/read/28397629/the-impact-of-life-stress-on-adult-depression-and-anxiety-is-dependent-on-gender-and-timing-of-exposure
#11
Carly E Herbison, Karina Allen, Monique Robinson, John Newnham, Craig Pennell
There is debate about the relative importance of timing of stressful events prenatally and over the life course and risk for subsequent depressive/anxious illness. The aim of this study was to examine the relative roles of prenatal stress and postnatal stress trajectories in predicting depression and anxiety in early adulthood in males and females. Exposure to life stress events was examined in the Western Australian Pregnancy Cohort (Raine) Study during pregnancy and ages 1, 2, 3, 5, 8, 10, 14, and 17 years...
April 11, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28392763/activation-in-context-differential-conclusions-drawn-from-cross-sectional-and-longitudinal-analyses-of-adolescents-cognitive-control-related-neural-activity
#12
Ethan M McCormick, Yang Qu, Eva H Telzer
Although immature cognitive control, subserved by late-developing prefrontal regions, has been proposed to underlie increased risk taking during adolescence, it remains unclear what patterns of PFC activation represent mature brain states: more or less activation? One challenge to drawing cogent conclusions from extant work stems from its reliance on single-time point neuroimaging and cross-sectional comparisons, which are ill-suited for assessing the complex changes that characterize adolescence. This necessitates longitudinal fMRI work to track within-subject changes in PFC function and links to risk-taking behavior, which can serve as an external marker for maturation of neural systems involved in cognitive control...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28388370/will-we-ever-agree-on-protein-requirements-in-the-intensive-care-unit
#13
L John Hoffer, Roland N Dickerson, Robert G Martindale, Stephen A McClave, Juan B Ochoa Gautier
The precise value of the normal adult protein requirement has long been debated. For many reasons-one of them being the difficulty of carrying out long-term nutrition experiments in free-living people-uncertainty is likely to persist indefinitely. By contrast, the controlled environment of the intensive care unit and relatively short trajectory of many critical illnesses make it feasible to use hard clinical outcome trials to determine protein requirements for critically ill patients in well-defined clinical situations...
April 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28381515/monophasic-demyelination-reduces-brain-growth-in-children
#14
Bérengère Aubert-Broche, Katrin Weier, Giulia Longoni, Vladimir S Fonov, Amit Bar-Or, Ruth Ann Marrie, E Ann Yeh, Sridar Narayanan, Douglas L Arnold, Leonard H Verhey, Brenda Banwell, D Louis Collins
OBJECTIVE: To investigate how monophasic acquired demyelinating syndromes (ADS) affect age-expected brain growth over time. METHODS: We analyzed 83 pediatric patients imaged serially from initial demyelinating attack: 18 with acute disseminated encephalomyelitis (ADEM) and 65 with other monophasic ADS presentations (monoADS). We further subdivided the monoADS group by the presence (n = 33; monoADSlesion) or absence (n = 32; monoADSnolesion) of T2 lesions involving the brain at onset...
April 5, 2017: Neurology
https://www.readbyqxmd.com/read/28378433/service-user-engagement-a-co-created-interview-schedule-exploring-mental-health-recovery-in-young-adults
#15
Claire-Odile Mccauley, Hugh Mckenna, Sinead Keeney, Derek McLaughlin
AIM: To co-create of an interview schedule exploring mental health recovery in collaboration with young adult service users. BACKGROUND: Service user involvement in research has been increasingly recognised as providing a vital authentic insight into mental health recovery. Engagement and collaboration with service users have facilitated the exploration of inaccessible or under-investigated aspects of the lived experience of mental health recovery, not only directing the trajectory of research, but making it relevant to their own contextual experience...
April 5, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28377472/time-to-improve-informed-consent-for-dialysis-an-international-perspective
#16
Frank Brennan, Cameron Stewart, Hannah Burgess, Sara N Davison, Alvin H Moss, Fliss E M Murtagh, Michael Germain, Shelley Tranter, Mark Brown
The literature reveals that current nephrology practice in obtaining informed consent for dialysis falls short of ethical and legal requirements. Meeting these requirements represents a significant challenge, especially because the benefits and risks of dialysis have shifted significantly with the growing number of older, comorbid patients. The importance of informed consent for dialysis is heightened by several concerns, including: (1) the proportion of predialysis patients and patients on dialysis who lack capacity in decision making and (2) whether older, comorbid, and frail patients understand their poor prognosis and the full implications to their independence and functional status of being on dialysis...
April 4, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28376887/women-with-family-cancer-history-are-at-risk-for-poorer-physical-quality-of-life-and-lower-self-efficacy-a-longitudinal-study-among-men-and-women-with-non-small-cell-lung-cancer
#17
Anna Banik, Ralf Schwarzer, Izabela Pawlowska, Monika Boberska, Roman Cieslak, Aleksandra Luszczynska
BACKGROUND: We investigated the determinants of trajectories of physical symptoms related to lung cancer (a quality of life [QOL] aspect) and self-efficacy among patients with non-small cell lung cancer (NSCLC). It was hypothesized that gender and family cancer history in first-degree relatives would have synergistic effects on QOL-lung cancer specific symptoms and self-efficacy. Women with family cancer history were expected to be at risk of poorer adjustment. METHODS: Quantitative, longitudinal design was applied...
April 4, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28370174/parents-early-healthcare-transition-experiences-with-preterm-and-acutely-ill-infants-a-scoping-review
#18
REVIEW
M Ballantyne, T Orava, S Bernardo, A C McPherson, P Church, D Fehlings
BACKGROUND: Parents undergo multiple transitions following the birth of an ill infant: their infant's illness-health trajectory, neonatal intensive care unit hospitalization and transfers from one healthcare setting to another, while also transitioning to parenthood. The objective of this review was to map and synthesize evidence on the experiences and needs of parents of preterm or ill infants as they transition within and between healthcare settings following birth. METHODS: The scoping review followed Arskey and O'Malley's () framework, enhanced by Levac et al...
March 30, 2017: Child: Care, Health and Development
https://www.readbyqxmd.com/read/28369257/neuroimaging-and-clinical-features-in-adults-with-a-22q11-2-deletion-at-risk-of-parkinson-s-disease
#19
Nancy J Butcher, Connie Marras, Margarita Pondal, Pablo Rusjan, Erik Boot, Leigh Christopher, Gabriela M Repetto, Rosemarie Fritsch, Eva W C Chow, Mario Masellis, Antonio P Strafella, Anthony E Lang, Anne S Bassett
The recurrent 22q11.2 deletion is a genetic risk factor for early-onset Parkinson's disease. Adults with the associated 22q11.2 deletion syndrome (22q11.2DS) may exhibit phenotypes that could help identify those at highest risk and reveal disease trajectories. We investigated clinical and neuroimaging features relevant to Parkinson's disease in 26 adults: 13 with 22q11.2DS at genetic risk of Parkinson's disease (mean age = 41.5 years, standard deviation = 9.7), 12 healthy age and sex-matched controls, and a 22q11...
March 24, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28364595/hippocampal-development-in-youth-with-a-history-of-childhood-maltreatment
#20
Casey Paquola, Maxwell R Bennett, Sean N Hatton, Daniel F Hermens, Inge Groote, Jim Lagopoulos
Childhood maltreatment (CM) is associated with enhanced risk of psychiatric illness and reduced subcortical grey matter in adulthood. The hippocampus and amygdala, due to their involvement in stress and emotion circuitries, have been subject to extensive investigations regarding the effect of CM. However, the complex relationship between CM, subcortical grey matter and mental illness remains poorly understood partially due to a lack of longitudinal studies. Here we used segmentation and linear mixed effect modelling to examine the impact of CM on hippocampal and amygdala development in young people with emerging mental illness...
March 27, 2017: Journal of Psychiatric Research
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