keyword
MENU ▼
Read by QxMD icon Read
search

xenon ct

keyword
https://www.readbyqxmd.com/read/29788388/persistent-metabolic-disturbance-in-the-perihemorrhagic-zone-despite-a-normalized-cerebral-blood-flow-following-surgery-for-intracerebral-hemorrhage
#1
Lovisa Tobieson, Sandro Rossitti, Peter Zsigmond, Jan Hillman, Niklas Marklund
BACKGROUND: We hypothesized that reduced cerebral blood flow (CBF) and/or energy metabolic disturbances exist in the tissue surrounding a surgically evacuated intracerebral hemorrhage (ICH). If present, such CBF and/or metabolic impairments may contribute to ongoing tissue injury and the modest clinical efficacy of ICH surgery. OBJECTIVE: To conduct an observational study of CBF and the energy metabolic state in the perihemorrhagic zone (PHZ) tissue and in seemingly normal cortex (SNX) by microdialysis (MD) following surgical ICH evacuation...
May 21, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29776385/generation-of-ventilation-perfusion-ratio-map-in-surgical-patients-by-dual-energy-ct-after-xenon-inhalation-and-intravenous-contrast-media
#2
Kohei Aoki, Yotaro Izumi, Wataru Watanabe, Yuji Shimizu, Hisato Osada, Norinari Honda, Toshihide Itoh, Mitsuo Nakayama
BACKGROUND: While many studies have evaluated the change in lung volume before and after lung resection and correlated this with pulmonary function test results, there is very little evidence on the changes in ventilation perfusion ratio (V/Q) before versus after lung resection. In the present pilot study, we evaluated if V/Q mapping can be constructed using dual energy CT images. METHODS: Thirty-one lung cancer patients planned for pulmonary resection were included in this study...
May 18, 2018: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29606339/a-feasibility-study-of-single-inhalation-single-energy-xenon-enhanced-ct-for-high-resolution-imaging-of-regional-lung-ventilation-in-humans
#3
Daniel W Pinkham, Mohammadreza Negahdar, Tokihiro Yamamoto, Erik Mittra, Maximilian Diehn, Viswam S Nair, Paul J Keall, Peter G Maxim, Billy W Loo
RATIONALE AND OBJECTIVES: The objective of this study was to assess the feasibility of single-inhalation xenon-enhanced computed tomography (XeCT) to provide clinically practical, high-resolution pulmonary ventilation imaging to clinics with access to only a single-energy computed tomography scanner, and to reduce the subject's overall exposure to xenon by utilizing a higher (70%) concentration for a much shorter time than has been employed in prior studies. MATERIALS AND METHODS: We conducted an institutional review board-approved prospective feasibility study of XeCT for 15 patients undergoing thoracic radiotherapy...
March 29, 2018: Academic Radiology
https://www.readbyqxmd.com/read/29588035/xenon-anesthesia-and-ct-noninvasive-measures-of-brain-anesthetic-concentration
#4
Andrew McKinstry-Wu, Charles W Carspecken, Alex Proekt, Max B Kelz
The existence of a barrier between anesthetic behavioral state transitions has been observed across phyla, but demonstrating that such a barrier exists and is not a pharmacokinetic artifact has not yet been possible in humans. Such an investigation requires temporally precise information regarding the brain concentration of anesthetic in order to demonstrate the specific pharmacokinetic-pharmacodynamic mismatch that is hysteresis. We propose a method to noninvasively determine brain tissue anesthetic concentration using computerized tomography and the radiopaque gaseous anesthetic xenon...
2018: Methods in Enzymology
https://www.readbyqxmd.com/read/29220212/comparison-of-xenon-enhanced-area-detector-ct-and-krypton-ventilation-spect-ct-for-assessment-of-pulmonary-functional-loss-and-disease-severity-in-smokers
#5
Yoshiharu Ohno, Yasuko Fujisawa, Daisuke Takenaka, Shigeo Kaminaga, Shinichiro Seki, Naoki Sugihara, Takeshi Yoshikawa
OBJECTIVE: The objective of this study was to compare the capability of xenon-enhanced area-detector CT (ADCT) performed with a subtraction technique and coregistered81m Kr-ventilation SPECT/CT for the assessment of pulmonary functional loss and disease severity in smokers. SUBJECTS AND METHODS: Forty-six consecutive smokers (32 men and 14 women; mean age, 67.0 years) underwent prospective unenhanced and xenon-enhanced ADCT,81m Kr-ventilation SPECT/CT, and pulmonary function tests...
February 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29157853/perfusion-imaging-in-acute-traumatic-brain-injury
#6
REVIEW
David B Douglas, Ruchir Chaudhari, Jason M Zhao, James Gullo, Jared Kirkland, Pamela K Douglas, Ely Wolin, James Walroth, Max Wintermark
Traumatic brain injury (TBI) is a significant problem worldwide and neuroimaging plays a critical role in diagnosis and management. Recently, perfusion neuroimaging techniques have been explored in TBI to determine and characterize potential perfusion neuroimaging biomarkers to aid in diagnosis, treatment, and prognosis. In this article, computed tomography (CT) bolus perfusion, MR imaging bolus perfusion, MR imaging arterial spin labeling perfusion, and xenon CT are reviewed with a focus on their applications in acute TBI...
February 2018: Neuroimaging Clinics of North America
https://www.readbyqxmd.com/read/29027859/quantitative-cerebral-blood-flow-using-xenon-enhanced-ct-after-decompressive-craniectomy-in-traumatic-brain-injury
#7
Aditya Vedantam, Claudia S Robertson, Shankar P Gopinath
OBJECTIVE Few studies have reported on changes in quantitative cerebral blood flow (CBF) after decompressive craniectomy and the impact of these measures on clinical outcome. The aim of the present study was to evaluate global and regional CBF patterns in relation to cerebral hemodynamic parameters in patients after decompressive craniectomy for traumatic brain injury (TBI). METHODS The authors studied clinical and imaging data of patients who underwent xenon-enhanced CT (XeCT) CBF studies after decompressive craniectomy for evacuation of a mass lesion and/or to relieve intractable intracranial hypertension...
October 13, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28983856/effect-of-hhh-therapy-on-regional-cbf-after-severe-subarachnoid-hemorrhage-studied-by-bedside-xenon-enhanced-ct
#8
Henrik Engquist, Elham Rostami, Elisabeth Ronne-Engström, Pelle Nilsson, Anders Lewén, Per Enblad
BACKGROUND: Management of delayed cerebral ischemia (DCI) following subarachnoid hemorrhage (SAH) is difficult and still carries controversies. In this study, the effect of therapeutic hypervolemia, hemodilution, and hypertension (HHH-therapy) on cerebral blood flow (CBF) was assessed by xenon-enhanced computerized tomography (XeCT) hypothesizing an increase in CBF in poorly perfused regions. METHODS: Bedside XeCT measurements of regional CBF in mechanically ventilated SAH patients were routinely scheduled for day 0-3, 4-7, and 8-12...
April 2018: Neurocritical Care
https://www.readbyqxmd.com/read/28762185/consideration-of-the-intracranial-pressure-threshold-value-for-the-initiation-of-traumatic-brain-injury-treatment-a-xenon-ct-and-perfusion-ct-study
#9
Mitsuru Honda, Ryo Ichibayashi, Ginga Suzuki, Hiroki Yokomuro, Yoshikatsu Seiki, Shigeru Sase, Taichi Kishi
BACKGROUND: Monitoring of intracranial pressure (ICP) is considered to be fundamental for the care of patients with severe traumatic brain injury (TBI) and is routinely used to direct medical and surgical therapy. Accordingly, some guidelines for the management of severe TBI recommend that treatment be initiated for ICP values >20 mmHg. However, it remained to be accounted whether there is a scientific basis to this instruction. The purpose of the present study was to clarify whether the basis of ICP values >20 mmHg is appropriate...
December 2017: Neurocritical Care
https://www.readbyqxmd.com/read/28745443/discrimination-between-patients-with-mild-alzheimer-s-disease-and-healthy-subjects-based-on-cerebral-blood-flow-images-of-the-lateral-views-in-xenon-enhanced-computed-tomography
#10
Shigeru Sase, Homaro Yamamoto, Ena Kawashima, Xin Tan, Yutaka Sawa
BACKGROUND: Quantitative cerebral blood flow (CBF) measurement is expected to help early detection of functional abnormalities caused by Alzheimer's disease (AD) and enable AD treatment to begin in its early stages. Recently, a technique of layer analysis was reported that allowed CBF to be analyzed from the outer to inner layers of the brain. The aim of this work was to develop methods for discriminating between patients with mild AD and healthy subjects based on CBF images of the lateral views created with the layer analysis technique in xenon-enhanced computed tomography...
January 2018: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
https://www.readbyqxmd.com/read/28670151/dual-energy-ct-new-horizon-in-medical-imaging
#11
REVIEW
Hyun Woo Goo, Jin Mo Goo
Dual-energy CT has remained underutilized over the past decade probably due to a cumbersome workflow issue and current technical limitations. Clinical radiologists should be made aware of the potential clinical benefits of dual-energy CT over single-energy CT. To accomplish this aim, the basic principle, current acquisition methods with advantages and disadvantages, and various material-specific imaging methods as clinical applications of dual-energy CT should be addressed in detail. Current dual-energy CT acquisition methods include dual tubes with or without beam filtration, rapid voltage switching, dual-layer detector, split filter technique, and sequential scanning...
July 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28648106/pressure-autoregulation-measurement-techniques-in-adult-traumatic-brain-injury-part-i-a-scoping-review-of-intermittent-semi-intermittent-methods
#12
Frederick A Zeiler, Joseph Donnelly, Leanne Calviello, David K Menon, Peter Smielewski, Marek Czosnyka
The purpose of this study was to perform a systematic, scoping review of commonly described intermittent/semi-intermittent autoregulation measurement techniques in adult traumatic brain injury (TBI). Nine separate systematic reviews were conducted for each intermittent technique: computed tomographic perfusion (CTP)/Xenon-CT (Xe-CT), positron emission tomography (PET), magnetic resonance imaging (MRI), arteriovenous difference in oxygen (AVDO2 ) technique, thigh cuff deflation technique (TCDT), transient hyperemic response test (THRT), orthostatic hypotension test (OHT), mean flow index (Mx), and transfer function autoregulation index (TF-ARI)...
December 1, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28574309/early-low-cerebral-blood-flow-and-high-cerebral-lactate-prediction-of-delayed-cerebral-ischemia-in-subarachnoid-hemorrhage
#13
Elham Rostami, Henrik Engquist, Timothy Howells, Ulf Johnson, Elisabeth Ronne-Engström, Pelle Nilsson, Lars Hillered, Anders Lewén, Per Enblad
OBJECTIVE Delayed cerebral ischemia (DCI) following subarachnoid hemorrhage (SAH) is one of the major contributors to poor outcome. It is crucial to be able to detect early signs of DCI to prevent its occurrence. The objective of this study was to determine if low cerebral blood flow (CBF) measurements and pathological microdialysis parameters measured at the bedside can be observed early in patients with SAH who later developed DCI. METHODS The authors included 30 patients with severe SAH. The CBF measurements were performed at Day 0-3 after disease onset, using bedside xenon-CT...
June 2, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28510483/improvement-in-ventilation-perfusion-mismatch-after-bronchoscopic-lung-volume-reduction-quantitative-image-analysis
#14
Sei Won Lee, Sang Min Lee, So Youn Shin, Tai Sun Park, Sang Young Oh, Namkug Kim, Yoonki Hong, Jae Seung Lee, Yeon-Mok Oh, Sang-Do Lee, Joon Beom Seo
Purpose To evaluate whether bronchoscopic lung volume reduction (BLVR) increases ventilation and therefore improves ventilation-perfusion (V/Q) mismatch. Materials and Methods All patients provided written informed consent to be included in this study, which was approved by the Institutional Review Board (2013-0368) of Asan Medical Center. The physiologic changes that occurred after BLVR were measured by using xenon-enhanced ventilation and iodine-enhanced perfusion dual-energy computed tomography (CT). Patients with severe emphysema plus hyperinflation who did not respond to usual treatments were eligible...
October 2017: Radiology
https://www.readbyqxmd.com/read/28505626/discrimination-between-patients-with-alzheimer-disease-and-healthy-subjects-using-layer-analysis-of-cerebral-blood-flow-and-xenon-solubility-coefficient-in-xenon-enhanced-computed-tomography
#15
Shigeru Sase, Homaro Yamamoto, Ena Kawashima, Xin Tan, Yutaka Sawa
OBJECTIVE: The aim of this study was to develop a method for discriminating between patients with Alzheimer disease (AD) and healthy subjects using layer analysis of cerebral blood flow (CBF) and xenon solubility coefficient (λ) in xenon-enhanced computed tomography (CT). METHODS: Xenon-enhanced CT was performed on 27 patients with AD (81.7 [3.3] years old) and 15 healthy volunteers (78.6 [4.0] years old) using a wide volume CT. For each subject, we created the first- (surface) to sixth-layer images of CBF and λ for the 6 viewing directions (layer thickness, 5 mm)...
May 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28368505/effects-of-cranioplasty-on-cerebral-blood-flow-following-decompressive-craniectomy-a-systematic-review-of-the-literature
#16
REVIEW
Sameer H Halani, Jason K Chu, James G Malcolm, Rima S Rindler, Jason W Allen, Jonathan A Grossberg, Gustavo Pradilla, Faiz U Ahmad
BACKGROUND: Cranioplasty after decompressive craniectomy (DC) is routinely performed for reconstructive purposes and has been recently linked to improved cerebral blood flow (CBF) and neurological function. OBJECTIVE: To systematically review all available literature to evaluate the effect of cranioplasty on CBF and neurocognitive recovery. METHODS: A PubMed, Google Scholar, and MEDLINE search adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines included studies reporting patients who underwent DC and subsequent cranioplasty in whom cerebral hemodynamics were measured before and after cranioplasty...
August 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28361248/increased-risk-of-critical-cbf-levels-in-sah-patients-with-actual-cpp-below-calculated-optimal-cpp
#17
Ulf Johnson, Henrik Engquist, Anders Lewén, Tim Howells, Pelle Nilsson, Elisabeth Ronne-Engström, Elham Rostami, Per Enblad
BACKGROUND: Cerebral pressure autoregulation can be quantified with the pressure reactivity index (PRx), based on the correlation between blood pressure and intracranial pressure. Using PRx optimal cerebral perfusion pressure (CPPopt) can be calculated, i.e., the level of CPP where autoregulation functions best. The relation between cerebral blood flow (CBF) and CPPopt has not been examined. The objective was to assess to which extent CPPopt can be calculated in SAH patients and to investigate CPPopt in relation to CBF...
June 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28107411/xenon-enhanced-dual-energy-ct-imaging-in-combined-pulmonary-fibrosis-and-emphysema
#18
Keishi Sugino, Masahiro Kobayashi, Yasuhiko Nakamura, Kyoko Gocho, Fumiaki Ishida, Kazutoshi Isobe, Nobuyuki Shiraga, Sakae Homma
BACKGROUND: Little has been reported on the feasibility of xenon-enhanced dual-energy computed tomography (Xe-DECT) in the visual and quantitative analysis of combined pulmonary fibrosis and emphysema (CPFE). OBJECTIVES: We compared CPFE with idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD), as well as correlation with parameters of pulmonary function tests (PFTs). METHODS: Studied in 3 groups were 25 patients with CPFE, 25 with IPF without emphysema (IPF alone), 30 with COPD...
2017: PloS One
https://www.readbyqxmd.com/read/28101162/correlation-between-high-perfusion-syndrome-and-stent-restenosis-after-stent-implantation
#19
Yingyi Li, Lingtao Tang, Dong Qi, Chunlei Wang, Suxia Zhang, Pengfei Hu, Yun Wang, Bogang Zhang, Kunxi Zhang
The present study was conducted to determine the correlation between high perfusion syndrome and stent restenosis after cerebral vascular stent implantation. A total of 146 patients diagnosed with cerebral vascular stenosis and stent implantation were selected. A total of 55 cases (37.67%) of cerebral hyperperfusion syndrome patients were diagnosed by xenon-enhanced computer tomography (Xe-CT) examination and clinical symptoms within 3 days after surgery and were chosen as the observation group. A total of 91 cases were selected as the control group...
December 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28099359/evaluation-of-pulmonary-function-using-single-breath-hold-dual-energy-computed-tomography-with-xenon-results-of-a-preliminary-study
#20
Hiroyuki Kyoyama, Yusuke Hirata, Satoshi Kikuchi, Kosuke Sakai, Yuriko Saito, Shintaro Mikami, Gaku Moriyama, Hisami Yanagita, Wataru Watanabe, Katharina Otani, Norinari Honda, Kazutsugu Uematsu
Xenon-enhanced dual-energy computed tomography (xenon-enhanced CT) can provide lung ventilation maps that may be useful for assessing structural and functional abnormalities of the lung. Xenon-enhanced CT has been performed using a multiple-breath-hold technique during xenon washout. We recently developed xenon-enhanced CT using a single-breath-hold technique to assess ventilation. We sought to evaluate whether xenon-enhanced CT using a single-breath-hold technique correlates with pulmonary function testing (PFT) results...
January 2017: Medicine (Baltimore)
keyword
keyword
37849
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"