Vincenzo Berghella

No abstract text is available yet for this article.

The preoperative preparation for cesarean delivery is a multistep approach for which protocols should exist at each hospital system. These protocols should be guided by the findings of this review. The interventions reviewed and recommendations made for this review have a common goal of decreasing maternal and neonatal morbidity and mortality related to cesarean delivery (CD). The preoperative time period starts prior to the patient's arrival to the hospital and ends immediately prior to skin incision. Skin cleansing in addition to CDC recommendations of showering with either soap or an antiseptic solution at least the night prior to a procedure has not been shown to further decrease rates of infection...

OBJECTIVE: We aimed to evaluate whether cerclage with progestogen therapy was superior to cerclage alone in the prevention of spontaneous preterm birth (sPTB) in singleton pregnancies METHODS: : This is an international retrospective cohort study of singleton pregnancies, without major anomaly or aneuploidy, and with cerclage placed at 10 different institutions in the United States and Colombia from June 2016-June 2020. Exclusion criteria were: lack of documentation regarding whether progestogen was or was not prescribed, delivery outcome unavailable, and pregnancy termination (spontaneous or induced) prior to 16 weeks' gestation...

OBJECTIVE: To evaluate the risk of spontaneous preterm birth (sPTB) with or without universal transvaginal ultrasound (TVU) cervical length (CL) screening at the time of mid-trimester scan. DATA SOURCES: Medline, Embase, ClinicalTrials.gov and Web of Science were systematically searched from the inception of the databases to November 12th, 2023 utilizing combinations of the relevant medical subject heading (MeSH) terms, keywords, and word variants that were considered suitable for the topic...

OBJECTIVE: We performed a systematic review and meta-analysis comparing maternal and neonatal outcomes of patients screened with one-step or two-step screening methods for GDM. DATA SOURCES: Pubmed, Scopus, Cochrane, ClinicalTrials.gov, and LILACS were searched from inception up to September 2022. STUDY ELIGIBILITY CRITERIA: Only randomized controlled trials (RCTs) were included. Studies that had overlapping populations were excluded (PROSPERO CRD42022358903)...

OBJECTIVE: To assess global trends in mean birth weights at term, as reported in peer-reviewed literature. DATA SOURCES: We searched electronically PubMed, Embase, and Web of Science up to September 2023, using combinations of the search terms: "birth weight"; "birth-weight"; "birthweight"; "trend". There were no restrictions based on language or geographic area. STUDY ELIGIBILITY CRITERIA: We included all ecological and observational studies reporting mean birth weight at term as a continuous numerical variable over time...

An accurate transvaginal ultrasound (TVU) cervical length (CL) is paramount to obtain the best prediction for preterm birth (PTB). TVU CL should be optimally obtained when a lower uterine segment (LUS) contraction (CTX) is not seen. For universal TVU CL screening at around 20 weeks, the options are to do the TVU soon after bladder void (LUS CTXs present in 16-43% of this approach), or to wait until the end of the anatomy scan (ideally within 30 minutes after bladder voiding) to decrease the chance of a LUS CTX...

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INTRODUCTION: The purpose of this study was to explore patient demographic factors associated with counseling against breastfeeding and concurrent marijuana use. METHODS: A cross-sectional study derived using data from the Centers for Disease Control and Prevention administered Pregnancy Risk Assessment Monitoring System (PRAMS) in collaboration with state and local health departments. This study sample included survey participants whose responses indicate they received counseling discouraging breastfeeding with concurrent marijuana use...

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OBJECTIVE: There are over 145 million births worldwide, with over 30 million cesarean deliveries (CD) yearly. There are limited data comparing the perinatal and maternal outcomes between planned CD and planned vaginal delivery (VD). The objective was to evaluate perinatal and maternal morbidity and mortality by meta-analysis of randomized controlled trials (RCTs) which randomized patients to either planned CD versus planned VD. DATA SOURCES: Scopus, PubMed, CINAHL, Cochrane Library, and the WHO Clinical trial databases were searched from inception through August 2022...

BACKGROUND: Pregnancies at high risk for maternal, fetal, or placental complications often necessitate induction of labor in the late preterm or early term period for delivery. Limited data exist on the safest method of induction to use in this specific patient population. OBJECTIVE: This study aimed to compare the combination of oxytocin plus a Cook balloon vs misoprostol plus a Cook balloon for induction of labor in high-risk pregnancies. STUDY DESIGN: We conducted an open-label, randomized controlled trial at a single institution from July 2020 to May 2022...

OBJECTIVE: This study was undertaken to examine the association between CL and the risk of adverse outcomes in placenta previa pregnancies. Additionally, the diagnostic accuracy of CL in predicting emergency cesarean delivery (CD) due to hemorrhage was evaluated. DATA SOURCES: PubMed, Web of Science and Embase were systematically searched up to January 21, 2023. STUDY ELIGIBILITY CRITERIA: Observational studies investigating the relationship between CL and maternal adverse outcomes in patients with placenta previa were considered eligible...

After the FDA pulled 17-hydroxyprogesterone caproate from the market for its use in prevention of recurrent spontaneous preterm birth, national societies have had mixed recommendations regarding the management of patients with a singleton pregnancy and prior spontaneous preterm birth. Here we highlight the randomized trial data and translational evidence supporting the use of vaginal progesterone for prevention of recurrent spontaneous preterm birth in singleton pregnancies. Prophylactic vaginal progesterone starting at 16 week 0 days every night should be offered to singletons with prior singleton spontaneous preterm birth regardless of cervical length, and continued along with placement of cerclage if a transvaginal ultrasound cervical length ≤25mm is detected at < 24 weeks...

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

Term prelabor rupture of membranes, defined as rupture of membranes before the onset of labor at ≥37 weeks of gestation, is a common obstetrical event occurring in 8% of pregnancies. However, most relevant guidelines are inconclusive regarding the management of this condition and the optimal timing of induction of labor. Here, we present evidence from randomized controlled trials and a recent meta-analysis indicating that an immediate induction of labor in term premature rupture of membranes is associated with several maternal and neonatal benefits compared with expectant management, without increasing the risk of cesarean delivery...

OBJECTIVE:  Preterm birth, defined as birth before 37 weeks of gestation, is a leading cause of perinatal and infant mortality throughout the world. Preterm birth is also associated with long-term neurological disabilities and other significant health issues in children. A short cervix in the second trimester has been noted to be one of the strongest predictors of subsequent spontaneous preterm birth in both singleton and multiple pregnancies. Some studies have shown that cervical support in the form of an Arabin pessary lowers the risk of preterm birth in women with a singleton gestation and short cervical length; however, other studies have conflicting results...