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Baha M. Sibai

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https://www.readbyqxmd.com/read/29579757/liberal-versus-indicated-maternal-oxygen-supplementation-in-labor-a-before-and-after-trial
#1
Nana-Ama E Ankumah, Sean C Blackwell, Mesk A Alrais, Farah H Amro, Rachel L Wiley, Patricia Heale, Maria Hutchinson, Baha M Sibai
BACKGROUND:  Although supplemental oxygen (SO2 ) is routinely administered to laboring gravidas, benefits and harms are not well studied. OBJECTIVE:  This article compares strategies of liberal versus indicated SO2 therapy during labor on cesarean delivery (CD) rate and neonatal outcomes. STUDY DESIGN:  A controlled, before-and-after trial of laboring women with term, singleton pregnancies. During an initial 8-week period, maternal SO2 was administered at the discretion of the provider followed by an 8-week period where SO2 was to be given only for protocol indications...
March 26, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29298455/preterm-preeclampsia-with-severe-features-composite-maternal-and-neonatal-morbidities-associated-with-fetal-growth-restriction
#2
Olaide Ashimi Balogun, Raminder K Khanagura, Heather R Kregel, Farah H Amro, Baha M Sibai, Suneet P Chauhan
OBJECTIVE:  The objective of this study was to compare adverse pregnancy outcomes between fetuses with estimated fetal weight (EFW) < 10 to > 10% in women with preterm preeclampsia (PE) with severe features. MATERIALS AND METHODS:  All women with preterm PE with severe features and nonanomalous singletons with EFW were identified at a tertiary center. Women with oligohydramnios or absent/reversed umbilical Doppler velocimetry were excluded. Using multivariable analysis, we compared the composite maternal and neonatal morbidities (CMM and CNM) between those with appropriate for gestational age (AGA) fetal growth, defined as EFW at 10 to 90th versus those with fetal growth restriction (FGR), defined as EFW < 10th percentile for gestational age (GA)...
January 3, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29276165/caesarean-delivery-surgical-site-infection-what-are-expected-rates-and-potentially-modifiable-risk-factors
#3
Ziad A Haidar, Susan Hosseini Nasab, Hind N Moussa, Baha M Sibai, Sean C Blackwell
OBJECTIVE: This study sought to determine baseline Caesarean delivery (CD) surgical site infection (SSI) rates in various patient subgroups and to identify potentially modifiable and non-modifiable risk factors for SSI. METHODS: This is a secondary analysis of a multicentre CD registry. Women who underwent CD were divided into SSI versus no SSI. SSI was defined as an infection that occurred in the part of the body where the surgery took place, within 30 days of surgery...
December 21, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28942717/composite-neonatal-and-maternal-morbidities-with-small-versus-appropriate-for-gestational-age-among-uncomplicated-obese-women-undergoing-repeat-cesarean-delivery
#4
Ziad A Haidar, Oscar A Viteri, Susan Hosseini Nasab, Hind N Moussa, Baha M Sibai, Janice E Whitty
PURPOSE: Our goal was to compare composite neonatal and maternal morbidities (composite neonatal morbidity (CNM), composite maternal morbidity (CMM)) among deliveries with small for age (SGA) versus appropriate for gestational age (AGA; birthweight 10-89%) among obese versus non-obese women undergoing repeat cesarean delivery (CD). STUDY DESIGN: This is a secondary analysis of a prospective observational study. Women who had elective CD ≥37 weeks were studied...
October 10, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28942691/twin-transvaginal-cervical-length-at-16-20-weeks-and-prediction-of-preterm-birth
#5
Ashley E Hester, Nana-Ama E Ankumah, Suneet P Chauhan, Sean C Blackwell, Baha M Sibai
OBJECTIVE: Our objective was to determine if transvaginal cervical length at 16-20 weeks is predictive of preterm birth <34 weeks in a large cohort of twin pregnancies. STUDY DESIGN: This is a secondary analysis from a randomized trial of 17 alpha-hydroxyprogesterone caproate in twins to prevent preterm birth. Transvaginal cervical length was performed at 16-20-week gestation. The inclusion criteria were non-anomalous twins with transvaginal cervical length at 16-20 weeks...
October 8, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28885417/association-of-nonsteroidal-antiinflammatory-drugs-and-postpartum-hypertension-in-women-with-preeclampsia-with-severe-features
#6
Oscar A Viteri, Joey A England, Mesk A Alrais, Kayla A Lash, Maria I Villegas, Olaide A Ashimi Balogun, Suneet P Chauhan, Baha M Sibai
OBJECTIVE: To estimate whether nonsteroidal antiinflammatory drugs (NSAIDs) are associated with persistent postpartum hypertension in a cohort of women with preeclampsia and severe features. METHODS: We conducted a retrospective cohort study at a single, tertiary center from January 2013 to December 2015. All women diagnosed with severe preeclampsia who remained hypertensive for greater than 24 hours after delivery were included. The primary outcome was the rate of persistent postpartum hypertension, defined as systolic blood pressure 150 mm Hg or greater or diastolic 100 mm Hg or greater (or both), on two occasions, at least 4 hours apart...
October 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28865040/the-impact-of-peri-operative-dexamethasone-administration-on-the-normal-hypothalamic-pituitary-adrenal-response-to-major-surgical-procedures
#7
Katia El-Sibai, Aman Rajpal, Ribal Al-Aridi, Warren R Selman, Baha M Arafah
BACKGROUND: Surgical procedures are associated with activation of the hypothalamic-pituitary-adrenal axis (HPA). Studies examining HPA dynamics peri-operatively are limited and the modulating influence of peri-operatively administered glucocorticoids on that is not well established. This investigation examined alterations in HPA function and the impact of dexamethasone (DEX) administration during the peri-operative period. METHODS: We examined HPA function in 297 patients with normal function who had surgical procedures including pituitary mass resection (n = 191), craniotomy (n = 17) and other thoracic/ abdominal/ pelvic surgeries (n = 89)...
October 2017: Endocrine
https://www.readbyqxmd.com/read/28708975/short-term-costs-of-preeclampsia-to-the-united-states-health-care-system
#8
Warren Stevens, Tiffany Shih, Devin Incerti, Thanh G N Ton, Henry C Lee, Desi Peneva, George A Macones, Baha M Sibai, Anupam B Jena
BACKGROUND: Preeclampsia is a leading cause of maternal morbidity and mortality and adverse neonatal outcomes. Little is known about the extent of the health and cost burden of preeclampsia in the United States. OBJECTIVE: This study sought to quantify the annual epidemiological and health care cost burden of preeclampsia to both mothers and infants in the United States in 2012. STUDY DESIGN: We used epidemiological and econometric methods to assess the annual cost of preeclampsia in the United States using a combination of population-based and administrative data sets: the National Center for Health Statistics Vital Statistics on Births, the California Perinatal Quality Care Collaborative Databases, the US Health Care Cost and Utilization Project database, and a commercial claims data set...
September 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28651448/adverse-pregnancy-outcomes-in-deliveries-prior-to-at-and-beyond-39-weeks-low-and-high-risk-women
#9
Hind N Moussa, Susan Hosseini Nasab, Farah H Amro, Jennifer Hoayek, Ziad A Haidar, Sean C Blackwell, Baha M Sibai
BACKGROUND: Hypertensive disorders are associated with maternal and neonatal complications. Though they are more common in women with history of prior preeclampsia, they can occur in uncomplicated pregnancies. OBJECTIVE: To determine the proportion of adverse pregnancy outcomes in deliveries prior to or at ≥39 weeks, in uncomplicated singleton nulliparous women (low-risk), as well as women with history of preeclampsia in a prior gestation (high-risk). STUDY DESIGN: This was a secondary analysis from the multicenter trials of low dose aspirin for preeclampsia prevention in low and high-risk pregnancies...
July 18, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28648694/removal-notice-to-the-relationship-between-primary-cesarean-delivery-skin-incision-type-and-wound-complications%C3%A2-in%C3%A2-women-with-morbid-obesity-am-j-obstet-gynecol-2014-210-319-e1-4
#10
Caroline C Marrs, Hind N Moussa, Baha M Sibai, Sean C Blackwell
This article has been removed: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been removed at the request of the Editors-in-Chief and Authors. The original publication reported that univariate analysis showed that a vertical skin incision in obese women undergoing Cesarean delivery was associated with a higher odds ratio for wound complications than a transverse skin incision. Multivariable analyses showed a reversal of the association (i...
July 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28400306/can-3-dimensional-power-doppler-indices-improve-the-prenatal-diagnosis-of-a-potentially-morbidly-adherent-placenta-in-patients-with-placenta-previa
#11
Ziad A Haidar, Ramesha Papanna, Baha M Sibai, Nina Tatevian, Oscar A Viteri, Patricia C Vowels, Sean C Blackwell, Kenneth J Moise
BACKGROUND: Traditionally, 2-dimensional ultrasound parameters have been used for the diagnosis of a suspected morbidly adherent placenta previa. More objective techniques have not been well studied yet. OBJECTIVE: The objective of the study was to determine the ability of prenatal 3-dimensional power Doppler analysis of flow and vascular indices to predict the morbidly adherent placenta objectively. STUDY DESIGN: A prospective cohort study was performed in women between 28 and 32 gestational weeks with known placenta previa...
August 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28348923/massive-urinary-protein-excretion-associated-with-greater-neonatal-risk-in-preeclampsia
#12
Julio Mateus, Roger Newman, Baha M Sibai, Qing Li, John R Barton, C Andrew Combs, Edwin Guzman, Kim A Boggess, Cynthia Gyamfi, Peter von Dadelszen, Doug Woelkers
Objective The objective of this study was to compare clinical outcomes of preeclamptic pregnancies according to the proteinuria level. Study Design Secondary analysis of a multicenter prospective cohort study of women with preeclampsia (PE) symptomatology. Nonproteinuria, mild-proteinuria, and massive-proteinuria PEs were defined as: < 165 mg in 12 hours or < 300 mg in 24 hours, 165 mg to 2.69 g in 12 hours or 300 mg to 4.99 g in 24 hours, and ≥ 2.7 g in 12 hours or ≥ 5...
January 2017: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/28249134/treatment-of-subclinical-hypothyroidism-or-hypothyroxinemia-in-pregnancy
#13
RANDOMIZED CONTROLLED TRIAL
Brian M Casey, Elizabeth A Thom, Alan M Peaceman, Michael W Varner, Yoram Sorokin, Deborah G Hirtz, Uma M Reddy, Ronald J Wapner, John M Thorp, George Saade, Alan T N Tita, Dwight J Rouse, Baha Sibai, Jay D Iams, Brian M Mercer, Jorge Tolosa, Steve N Caritis, J Peter VanDorsten
BACKGROUND: Subclinical thyroid disease during pregnancy may be associated with adverse outcomes, including a lower-than-normal IQ in offspring. It is unknown whether levothyroxine treatment of women who are identified as having subclinical hypothyroidism or hypothyroxinemia during pregnancy improves cognitive function in their children. METHODS: We screened women with a singleton pregnancy before 20 weeks of gestation for subclinical hypothyroidism, defined as a thyrotropin level of 4...
March 2, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28121812/in-reply
#14
Baha M Sibai, Dwight J Rouse
No abstract text is available yet for this article.
February 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28106645/foreword
#15
Baha M Sibai
No abstract text is available yet for this article.
March 2017: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28059847/angiogenic-and-antiangiogenic-markers-for-prediction-and-risk-classification-of-preeclampsia
#16
Amol K Malshe, Baha M Sibai
Preeclampsia is a pregnancy-specific hypertensive disorder with multisystem involvement and is a significant cause of obstetric morbidity and mortality worldwide. A major issue in the treatment of preeclampsia stems from its still significant rates of misclassification and misdiagnosis. Angiogenic factors have been speculated as a possible diagnostic modality due to a perceived imbalance in angiogenesis in preeclampsia. Factors currently studied include soluble fms-like protein kinase 1 and placental growth factor...
March 2017: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28059842/counseling-management-and-outcome-in-women-with-severe-preeclampsia-at-23-to-28-weeks-gestation
#17
Olaide A Ashimi Balogun, Baha M Sibai
Preeclampsia with severe features (SPE) remote from term remains a major cause of maternal morbidity and mortality worldwide. With increasing diagnosis of SPE remote from term and improved methods for monitoring maternal and fetal well-being, several challenges have been made regarding management of preeclampsia. We reviewed the scientific literature of the diagnosis and outcome of SPE before 28 weeks. On the basis of this review, we will present our recommendations on management of SPE before 28 weeks' gestation...
March 2017: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28031980/obesity-epidemic-impact-from-preconception-to-postpartum
#18
REVIEW
Hind N Moussa, Mesk A Alrais, Mateo G Leon, Elizabeth L Abbas, Baha M Sibai
The obesity epidemic is on the rise throughout the USA and the world. Not only does it affect the general population but it also specifically poses unique threats to a woman's life in the antepartum, peripartum and postpartum periods. An increased BMI is associated with worse perinatal outcomes, including higher rates of preeclampsia (and other hypertensive disorders), macrosomia, other neonatal morbidities and gestational diabetes. Isolated maternal obesity and additional maternal diabetes predispose the infant to potential adult disease through fetal programming...
September 2016: Future Science OA
https://www.readbyqxmd.com/read/28031963/folic-acid-supplementation-what-is-new-fetal-obstetric-long-term-benefits-and-risks
#19
REVIEW
Hind N Moussa, Susan Hosseini Nasab, Ziad A Haidar, Sean C Blackwell, Baha M Sibai
The association between folic acid supplementation, prior to conception and/or during pregnancy and pregnancy outcomes, has been the subject of numerous studies. The worldwide recommendation of folic acid is at least 0.4 mg daily for all women of reproductive age, and 4-5 mg in high-risk women. In addition, evidence shows that folic acid supplementation could modulate other adverse pregnancy outcomes, specifically, in pregnancies complicated by seizure disorders, preeclampsia, anemia, fetal growth restriction and autism...
June 2016: Future Science OA
https://www.readbyqxmd.com/read/28031961/fetal-origins-of-autism-spectrum-disorders-the-non-associated-maternal-factors
#20
REVIEW
Hind N Moussa, Anand Srikrishnan, Sean C Blackwell, Pramod Dash, Baha M Sibai
AIM: Several population-based studies have been conducted to determine whether maternal exposures are involved in the pathophysiology of autism spectrum disorder (ASD). We review these studies and describe the factors not associated with increased risk for ASD development. METHODS: We identified studies describing associations between maternal exposures and ASD development. These studies include the Childhood Autism Risks from Genetics and the Environment, Nurses' Health Study II, and the Swedish population registry...
June 2016: Future Science OA
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