J-W Xiang, Z-G Chen, L Gong, Y Xiao, W-J Qing, L Wang, X-H Hu, Z-X Huang, R-L Qi, T-H Yang, A-P Arrigo, L Zhang, X-C Tang, S Huang, F-Y Liu, Z-W Luo, Y-F Liu, Q Sun, J Gigantelli, Y-Z Liu, D W-C Li
Sumoylation, a post-translational modification discovered over a decade ago, turns out to be a very important regulatory mechanism mediating multiple cellular processes. Recent studies from our laboratory and others also revealed that it plays a crucial role in regulating both differentiation and pathogenesis of the ocular lenses. This review will summarize these progresses.
January 9, 2017: Current Molecular Medicine