keyword
https://read.qxmd.com/read/37882847/the-development-of-paranasal-sinuses-in-patients-with-cystic-fibrosis-sinuses-volume-analysis
#1
JOURNAL ARTICLE
Agata Kaluzna-Mlynarczyk, Beata Pucher, Jakub Sroczynski, Michal Kotowski, Katarzyna Jonczyk-Potoczna, Jarosław Szydlowski
BACKGROUND: Cystic fibrosis (CF) is a severe systemic disease that affects many aspects of patients' lives. It is known that the progression of the disease adversely affects lower and upper airways including the paranasal sinuses. However, its impact on sinus development in the pediatric population is not fully examined. The purpose of this study was to evaluate the development of the paranasal sinuses in a pediatric population with CF and compare it to a control group consisting of healthy children...
October 26, 2023: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/37142567/a-functional-snp-in-mir-146a-and-genetic-susceptibility-to-drug-resistant-epilepsy
#2
JOURNAL ARTICLE
Hoiyda A Abdel-Rasol, Hadeer Abdel Ghaffar, Marwa S Mohamed, Rosa W Jad, Omayma O Abelaleem, Noha K Abdelghaffar
OBJECTIVES: The study aimed to assess the relationship between the functional single nucleotide polymorphism (SNP) (rs57095329) of miR-146a, the progression of drug-resistant epilepsy (DRE), and the severity of the disease (seizure frequency) in a group of Egyptian children epilepsy patients. SUBJECTS AND METHODS: 110 Egyptian children were recruited and divided into two groups, the epilepsy patients ( n  = 60) and the healthy control children ( n  = 50)...
May 4, 2023: Neurological Research
https://read.qxmd.com/read/36193216/congenital-giant-megaureter-prenatally-diagnosed-a-case-report
#3
Souha Laarif, Aida Daïb, Rabiaa Ben Abdallah, Cyrine Saadi, Youssef Hellal, Nejib Kaabar
Congenital giant megaureter (CGM) is uncommon in pediatic population, defined as congenital localized or total dilatation of the ureter to over 10 times the normal diameter with a normal bladder. Herein, we reported an entirely dilated CGM presented as neonatal bowel obstruction in a newborn baby. Our experience has suggested that CGM should be considered as a differential diagnosis of abdominal distension and occlusive syndrome.
November 2022: Urology Case Reports
https://read.qxmd.com/read/36052266/whole-transcriptome-sequencing-reveals-a-tcf4-znf384-fusion-in-acute-lymphoblastic-leukemia
#4
JOURNAL ARTICLE
Zhengyu Wu, Fang Zhang, Chengzhu Liu, Shuhong Shen, Jinhua Chu, Linhai Yang, Zhiwei Xie, Yu Liu, Kangkang Liu, Ningling Wang
Previous studies have shown that, the clinical features and prognosis of ZNF384-rearranged pediatric acute lymphoblastic leukemia (ALL) depend on its translocation partners. We report two cases of TCF4-ZNF384 fusion, one 6-year-old girl and one 10-year-old boy, both diagnosed by whole-transcriptome sequencing, and TCF4 is the newest fusion partner of ZNF384. As illustrated in this first report of TCF4-ZNF384 fusion in ALL patients, the identification of patients with ZNF384 rearrangement in ALL patients is critical to elucidate outcomes associated with a specific rearrangement and to develop appropriate treatment strategies...
2022: Frontiers in Oncology
https://read.qxmd.com/read/35912470/pediatic-code-blue-event-anaylsis-performance-of-non-acute-health-care-providers
#5
JOURNAL ARTICLE
Graham Chamberlain, Ronish Gupta, Anna-Theresa Lobos
In-hospital pediatric cardiopulmonary arrest is rare. With more than 50% of patients not surviving to discharge following cardiopulmonary arrest, it is important that health-care providers (HCPs) respond appropriately to deteriorating patients. Our study evaluated the performance of basic life support skills using non-acute HCPs during pediatric inpatient resuscitation events. We conducted a retrospective chart review of all code blue team (CBT) activations in non-acute care areas of a tertiary care children's hospital from 2008 to 2017...
December 2022: Medical Education Online
https://read.qxmd.com/read/35076418/covid-19-in-pediatric-palliative-care-what-can-we-learn-from-the-pandemic-and-possible-future-directions
#6
JOURNAL ARTICLE
Irene Avagnina, Anna Zanin, Pierina Lazzarin, Enrica Grigolon, Aashni Shahi, Simonetta Papa, Luca Giacomelli, Franca Benini
INTRODUCTION: Patients in pediatric palliative care (PPC) live with multiple comorbidities which represent a risk factor for severe form of COVID-19. METHODS: This monocentric retrospective study was performed at the PPC Center of Padua (Italy). Testing methodology, prevention strategies and infection characteristics were documented and compared during the first and second peak of SARS-CoV-2 infection. RESULTS: Between April-June 2020 a population swab screening was performed and a strong reduction of the habitual family support was observed...
October 2021: Annali Dell'Istituto Superiore di Sanità
https://read.qxmd.com/read/34965644/effect-of-the-sars-cov-2-pandemic-on-the-control-and-severity-of-pediatric-asthma
#7
JOURNAL ARTICLE
Silvia Sánchez-García, Javier Ruiz-Hornillos, Marta Bernaola, Alicia Habernau-Mena, Eva María Lasa, Javier Contreras, Rocío Candón-Morillo, Cristina Antón-Rodríguez, Carmelo Escudero
BACKGROUND: The novel disease caused by the new coronavirus SARS-CoV-2 has caused an unprecedented global pandemic. Care providers of asthmatic children are increasingly con-cerned; as viral infections are one of the primary triggers of asthma flare-up. However, the effect of SARS-CoV-2 as well as the generated worldwide lockdown on asthmatic children is unknown. OBJECTIVE: The aim of this study was to analyze the effects of pandemic SARS-CoV-2 in pediat-ric asthma control...
2022: Allergologia et Immunopathologia
https://read.qxmd.com/read/33290203/acute-phenobarbital-poisoning-for-the-management-of-seizures-in-newborns-and-children-a-systematic-literature-review
#8
JOURNAL ARTICLE
Adel Ghorani-Azam, Mahdi Balali-Mood, Bamdad Riahi-Zanjani, Emadodin Darchini-Maragheh, Mahmood Sadeghi
OBJECTIVES: While phenobarbital (PB) is commonly used for the management of seizures in newborns and pediatrics, its administration may accompany acute poisoning. We aimed to review the literature to find out the frequency of PB poisonings in newborns and children with seizures. METHOD: A literature search was performed by two independent reviewers to find relevant articles about PB toxicity in neonates and pediatrics that were treated for the seizure. RESULTS: 18 articles met the inclusion criteria and were included in this systematic review...
2021: CNS & Neurological Disorders Drug Targets
https://read.qxmd.com/read/32842384/-clinical-characteristics-of-carbapenem-resistant-enterobacteriaceae-infection-in-pediatric-liver-transplantation-recipients
#9
JOURNAL ARTICLE
Y Sun, H Zheng, J L Zhang, L X Yu, B Wang, W Gao, J Z Cai, Y H Liu
Objective: To explore the clinical features and treatment of carbapenem-resistant Enterobacteriaceae (CRE) infection in pediatric liver transplantation recipients and discuss the significance of CRE colonization by screening with rectal swabs. Methods: A total of 286 cases of pediatic liver transplantation recipients, who came from Tianjin First Central Hospital during August 1,2017 to August 1, 2018, were retrospectively investigated. The clinical characteristics, antibiotic susceptibity test, treatment outcomes and prognosis of CRE infection patients were analyzed...
August 2, 2020: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://read.qxmd.com/read/32804392/nurses-perceived-emergency-preparedness-knowledge-an-opportunity-for-improvement
#10
JOURNAL ARTICLE
Julie Bulson
OBJECTIVE: This study aimed to provide foundational data supporting the need for nursing education focused on emergency preparedness and response for nursing staff. DESIGN: This study is a cross-sectional, quantitative, descriptive, correlational quality improvement study. SETTING: The study location is a Midwest healthcare system comprised of 14 acute care facilities including pediat-ric and adult level I trauma centers, a burn center, and a fully dedicated pediatric hospital; five long-term care facilities; 230 ambulatory sites; 4,200 employed providers; and a health plan...
April 2020: American Journal of Disaster Medicine
https://read.qxmd.com/read/32441038/nurses-perceived-emergency-preparedness-knowledge-an-opportunity-for-improvement
#11
JOURNAL ARTICLE
Julie Bulson
OBJECTIVE: This study aimed to provide foundational data supporting the need for nursing education focused on emergency preparedness and response for nursing staff. DESIGN: This study is a cross-sectional, quantitative, descriptive, correlational quality improvement study. SETTING: The study location is a Midwest healthcare system comprised of 14 acute care facilities including pediat-ric and adult level I trauma centers, a burn center, and a fully dedicated pediatric hospital; five long-term care facili-ties; 230 ambulatory sites; 4,200 employed providers; and a health plan...
May 2020: Journal of Emergency Management: JEM
https://read.qxmd.com/read/32049781/ursodeoxycholic-acid-use-is-associated-with-significant-risk-of-morbidity-and-mortality-in-infants-with-cholestasis-a-strobe-compliant-study
#12
JOURNAL ARTICLE
Magd Ahmed Kotb, Dalia Mosallam, Christine William Shaker Basanti, Sally Talaat Mostafa El Sorogy, Ahmed M Badr, Hend El Hosainy Abd El Baky, Iman Hassan Draz
The off-label use of medications is a "right" for pediatricians, owing to lack of enough safety and effectiveness drug trials in pediatric age group. Pediatricians have to rely on their personal judicial use of medications in children.We studied off-label use of ursodeoxycholic acid (UDCA) retrospectively during 2005 to 2015 among those who attended the Pediatic Hepatology Unit, Cairo University.We analyzed data of 779 neonates and infants with cholestasis. 15% dropped out. Males comprised 374 (56.5%). Cholestasis was due to surgical causes in 129 (19...
February 2020: Medicine (Baltimore)
https://read.qxmd.com/read/30737856/factors-complicating-the-informed-consent-process-for-whole-exome-sequencing-in-neonatal-and-pediatic-intensive-care-units
#13
JOURNAL ARTICLE
Callie J Diamonstein
Whole exome and whole genome sequencing (WES/WGS) is increasingly utilized in inpatient settings such as neonatal and pediatric intensive care units (ICU), but no research has explored the process of informed consent in this setting. My experience as an inpatient genetic counselor has illuminated factors unique to the ICU that may threaten elements of informed consent such as voluntariness, disclosure, understanding, and capacity. I present three cases that exemplify elements complicating consent counseling for WES/WGS in the ICU, including the emotional state of the parents, involvements of other healthcare providers, environmental distractions and competing clinical priorities...
April 2019: Journal of Genetic Counseling
https://read.qxmd.com/read/29227200/telepsychiatry-for-children-and-adolescents-a-review-of-the-prometted-project
#14
JOURNAL ARTICLE
Catherine M Doyen, Marie-Joëlle Oreve, Eric Desailly, Virginie Goupil, Kevin Zarca, Yann L'Hermitte, Pauline Chaste, Marie-Ode Bau, Didier Beaujard, Sliman Haddadi, Ana Bibay, Yves Contejean, Marie-Thérèse Coutrot, Liora Crespin, Isabelle Frioux, Mario Speranza, Nolwenn Francois, Kelley Kaye
BACKGROUND: Telemedicine for children and adolescents is a public health topic, and since 2009 in France, the legal framework defines practical modalities. Some children with Attention Deficit with or without Hyperactivity Disorder, social anxiety, or Autism Spectrum Disorder (ASD) can be easily engaged within a teleconsultation model. Literature suggests new opportunities to facilitate the care process for the ASD person and his family: diagnosis with the use of validated instruments and parental accompaniment...
January 2018: Telemedicine Journal and E-health
https://read.qxmd.com/read/28702703/transfixing-kirshner-wires-for-fixation-of-intertrochanteric-valgus-osteotomies-in-management-of-pediatric-coxa-vara
#15
JOURNAL ARTICLE
Ahmed Shawkat Rizk
BACKGROUND: Coxa vara is a radiological term describing a decrease in the neck-shaft angle to 120° or less. Coxa vara is associated with pathomechanical changes that can manifest clinically. If left untreated, coxa vara can affect the normal development of the pediatric hip. Valgus osteotomy is the standard surgical treatment for coxa vara, but there is no consensus regarding the optimal osteotomy technique and fixation method. The work reported here aimed to highlight transfixing wires as a fixation method for valgus osteotomy applied as treatment for various types of pediatric coxa vara...
December 2017: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
https://read.qxmd.com/read/28046437/th-b-207b-02-optimizing-pediatic-cardiovascular-mri
#16
JOURNAL ARTICLE
J Deng
This imaging educational program will focus on solutions to common pediatric image quality optimization challenges. The speakers will present collective knowledge on best practices in pediatric imaging from their experience at dedicated children's hospitals. One of the most commonly encountered pediatric imaging requirements for the non-specialist hospital is pediatric CT in the emergency room setting. Thus, this educational program will begin with optimization of pediatric CT in the emergency department. Though pediatric cardiovascular MRI may be less common in the non-specialist hospitals, low pediatric volumes and unique cardiovascular anatomy make optimization of these techniques difficult...
June 2016: Medical Physics
https://read.qxmd.com/read/26878178/a-nanny-versus-daycare-is-there-a-right-choice
#17
JOURNAL ARTICLE
Valerie Kimball
As spring is on the horizon, my children begin to anticipate the end of the school year with thoughts of sleeping in, free days at the pool, and long evenings outside with friends. I, too, look forward to this time of the year, and a much needed hiatus from coaxing kids out of bed, making school lunches, and homework help in the evenings. However, I do not look forward to finding a new "kid sitter" for my preteens and teenager. Choice of childcare is perceived as perhaps one of the most stressful decisions parents must make for their children...
February 2016: Pediatric Annals
https://read.qxmd.com/read/24782686/survey-results-characterization-of-direct-thrombin-inhibitor-use-in-pediatric-patients
#18
JOURNAL ARTICLE
Alexandra Oschman
OBJECTIVES: The objective of this multicenter survey is to characterize the use of direct thrombin inhibitors (DTIs) in the pediatric population. The results of this survey may be used to design a prospective multicenter study with the ultimate goal of developing a dosing/titration recommendation for the use of DTIs in the pediatric population. METHODS: This is a multicenter, descriptive study to survey hospitals around the country regarding the use of DTIs (argatroban, bivalirudin, and lepirudin) in the pediatic population...
January 2014: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://read.qxmd.com/read/24485258/laparoscopic-surgery-for-gastro-esophageal-acid-reflux-disease
#19
REVIEW
Marlies P Schijven, Suzanne S Gisbertz, Mark I van Berge Henegouwen
Gastro-esophageal reflux disease is a troublesome disease for many patients, severely affecting their quality of life. Choice of treatment depends on a combination of patient characteristics and preferences, esophageal motility and damage of reflux, symptom severity and symptom correlation to acid reflux and physician preferences. Success of treatment depends on tailoring treatment modalities to the individual patient and adequate selection of treatment choice. PubMed, Embase, The Cochrane Database of Systematic Reviews, and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) were searched for systematic reviews with an abstract, publication date within the last five years, in humans only, on key terms (laparosc* OR laparoscopy*) AND (fundoplication OR reflux* OR GORD OR GERD OR nissen OR toupet) NOT (achal* OR pediat*)...
February 2014: Best Practice & Research. Clinical Gastroenterology
https://read.qxmd.com/read/23487499/comparison-of-hospital-wide-and-age-and-location-stratified-antibiograms-of-s-aureus-e-coli-and-s-pneumoniae-age-and-location-stratified-antibiograms
#20
Sanjeev K Swami, Ritu Banerjee
BACKGROUND: Antibiograms created by aggregating hospital-wide susceptibility data from diverse patients can be misleading. To demonstrate the utility of age- and location-stratified antibiograms, we compared stratified antibiograms for three common bacterial pathogens, E. coli, S. aureus, and S. pneumoniae. We created stratified antibiograms based on patient age (<18 years, 18-64 years, >/=65 years), and inpatient or outpatient location using all 2009 E. coli and S. aureus, and all 2008-2009 S...
December 2013: SpringerPlus
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