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children vitamin d

In-Ja Kim, Heung-Soo Lee, Hyun-Jeong Ju, Ja-Young Na, Hyo-Won Oh
BACKGROUND: A recent study in Canada reported that vitamin D deficiency is associated with dental caries. Because Koreans have been reported to be deficient in vitamin D, we investigated the relationship between dental caries and reduced serum vitamin D levels in Korean children. The purpose of this study was to analyze the relationships between blood vitamin D [25(OH)D] concentrations and dental caries in the permanent dentition of Korean children. METHODS: Data were collected from the Korea National Health and Nutrition Examination Survey performed in 2008-2013...
March 13, 2018: BMC Oral Health
Ushma Wadia, Wayne Soon, Paola Chivers, Aesen Thambiran, David Burgner, Sarah Cherian, Aris Siafarikas
Vitamin D deficiency is highly prevalent in newly settled refugees in Western Australia (WA). If adherence to daily vitamin D therapy is problematic, depot therapy is a therapeutic alternative. The aim of this study was to compare daily versus depot treatment and factors influencing the therapeutic outcome. Newly settled refugees ( n = 151) with 25(OH)D levels less than 78 nmol/L were randomised to receive daily or depot vitamin D therapy with eight weekly interval follow up to 40 weeks. Biochemical and clinical parameters were collected at each visit...
March 13, 2018: Nutrients
Elvira Larqué, Eva Morales, Rosaura Leis, José E Blanco-Carnero
BACKGROUND: To what extent does the circulating 25-hydroxyvitamin D (25[OH]D) concentration help to meet the physiological needs of humans is an ongoing subject of debate. Remaining unexposed to the sun to reduce melanoma cancer risk, current lifestyle with less out door activities, and increasing obesity rates, which in turn increases the storage of vitamin D in the adipose tissue, are presumably factors that contribute to the substantial upsurge in the prevalence of vitamin D deficiency in humans...
March 13, 2018: Annals of Nutrition & Metabolism
Takuo Kubota, Hirofumi Nakayama, Taichi Kitaoka, Yosikazu Nakamura, Seiji Fukumoto, Ikuma Fujiwara, Yukihiro Hasegawa, Kenji Ihara, Sachiko Kitanaka, Satomi Koyama, Satoshi Kusuda, Haruo Mizuno, Keisuke Nagasaki, Koji Oba, Yuko Sakamoto, Noriyuki Takubo, Toshiaki Shimizu, Yusuke Tanahashi, Kosei Hasegawa, Hirokazu Tsukahara, Tohru Yorifuji, Toshimi Michigami, Keiichi Ozono
There is concern that vitamin D deficiency is prevalent among children in Japan as well as worldwide. We conducted a nationwide epidemiologic survey of symptomatic vitamin D deficiency to observe its incidence rate among Japanese children. A questionnaire inquiring the number of new patients with vitamin D deficiency rickets and/or hypocalcemia for 3 years was sent to 855 randomly selected hospitals with a pediatrics department in Japan. In this survey, we found that 250 children were diagnosed with symptomatic vitamin D deficiency...
March 10, 2018: Endocrine Journal
Mya Thway Tint, Mary F Chong, Izzuddin M Aris, Keith M Godfrey, Phaik Ling Quah, Jeevesh Kapur, Seang Mei Saw, Peter D Gluckman, Victor S Rajadurai, Fabian Yap, Michael S Kramer, Yap-Seng Chong, Christiani Jeyakumar Henry, Marielle V Fortier, Yung Seng Lee
OBJECTIVES: Lower vitamin D status has been associated with adiposity in children through adults. However, the evidence of the impact of maternal vitamin-D status during pregnancy on offspring's adiposity is mixed. The objective of this study was to examine the associations between maternal vitamin-D [25(OH)D] status at mid-gestation and neonatal abdominal adipose tissue (AAT) compartments, particularly the deep subcutaneous adipose tissue linked with metabolic risk. METHODS: Participants (N = 292) were Asian mother-neonate pairs from the mother-offspring cohort, Growing Up in Singapore Towards healthy Outcomes...
March 9, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
Joanna Zapolska, Katarzyna Witczak-Sawczuk, Maryna Krawczuk-Rybak, Małgorzata Sawicka-Żukowska, Joanna Smarkusz, Lucyna Ostrowska
Background: Properly balanced diet and exercise are an essential element of healthy living for children and adolescents. Particular attention should be paid to nutrition and physical activity among juniors after cancer treatment, which is one of the most important elements of the convalescence period. Objective: The aim of the study was a comparative analysis of diet, physical activity of healthy children and adolescents with patients after cancer treatment. Material and methods: The study involved 60 children and adolescents; 30 healthy juniors and 30 patients after treatment for cancer...
2018: Roczniki Państwowego Zakładu Higieny
Aynur Amanzholkyzy, Rose E Nurgalieva, Arystan Zh Dosimov, Edgaras Stankevicius, Ayman T Kaldybaeva
BACKGROUND (OBJECTIVES): The objective of the article is studying the connection of VDR gene polymorphisms with bone tissue mineral density and biochemical marker of 25-PO vitamin D in adolescents of both ethnic groups, living in Western Kazakhstan Region. METHODS: The study included 110 relatively healthy children aged 13-18 years of Aktobe, the representatives of Kazakh ethnic group e 66 (Kazakh children) and Slavonic e 44 (Russian children). The groups were formed according to BTMD data, ethnic affiliation and according to content of vitamin D and gene polymorphism of vitamin D (VDR)...
February 2018: Journal of the National Medical Association
Wei Li, Xianfen Cheng, Linying Guo, Hongri Li, Chunrong Sun, Xiaodai Cui, Qi Zhang, Guowei Song
We assessed the relationship between serum 25-hydroxyvitamin D (25(OH)D) level and community-acquired pneumonia (CAP) among Chinese children.This observational study examined children aged 3 days to 14 years (n = 1582) from the Capital Institute of Pediatrics in 2009 to 2011. There were 797 children in the CAP group and 785 controls. The CAP group was divided into 2 groups: a pneumonia group and pneumonia-induced sepsis group. The serum 25(OH)D level was estimated using micro whole blood chemiluminescence...
January 2018: Medicine (Baltimore)
Philippe Hernigou, Jean Charles Auregan, Arnaud Dubory
The vitamin D history started early in the evolution of life (billion years ago) as a photochemical reaction producing an inert molecule. During the early evolution of vertebrates, this molecule became essential for calcium and bone homeostasis of terrestrial animals and arrived to the status of hormone. Phytoplankton, zooplankton, and most plants and animals that are exposed to sunlight have the capacity to make vitamin D. Vitamin D is critically important for the development, growth, and maintenance of a healthy skeleton from birth until death...
March 5, 2018: International Orthopaedics
Bikrant Bihari Lal, Seema Alam, Rajeev Khanna, Dinesh Rawat
There are no evidence-based recommendations on the ideal dose and regimen for supplementation of vitamin D in children with chronic liver disease (CLD). This study aimed to compare the safety and efficacy of weekly and stoss regimens for treatment of vitamin D deficiency in these children. Children between the ages of 1 to 18 years with CLD and hypovitaminosis D defined by 25-OH vitamin D (25(OH)D) < 30µg/l were included. They were randomized to receive either stoss regimen (600,000 IU on day 1) or weekly (60,000 IU weekly) regimen of vitamin D...
March 4, 2018: European Journal of Pediatrics
Hua-Hong Wu, Hui Li, Ya-Qin Zhang, Xin-Nan Zong, Zong-Han Zhu, Yang Yu
AIM: This 2015 study was part of The National Growth Survey of Children under seven years of age, which has been carried out in nine Chinese cities every 10 years since 1975. Our aim was to assess children's feeding practices and nutritional supplements. METHODS: This was a cross-sectional survey of 89,006 healthy children aged one to 24 months. All data were collected by face-to-face interviews during child health visits, using a questionnaire. RESULTS: The exclusive breastfeeding rate was 53% in infants under six months of age and the continued breastfeeding rate was 51% among infants who were 10-12 months and 5% when they were 21-24 months...
March 2, 2018: Acta Paediatrica
Afaf El-Ansary, John J Cannell, Geir Bjørklund, Ramesa Shafi Bhat, Abeer M Al Dbass, Hanan A Alfawaz, Salvatore Chirumbolo, Laila Al-Ayadhi
Autism spectrum disorder (ASD) affects about 1% of the world's population. Vitamin D is thought to be essential for normal brain development and modulation of the immune system. Worldwide about 1 billion people are affected by vitamin D deficiency. High-sensitivity C-reactive protein (hs-CRP), cytochrome P450 2E1 (CYP2E1) and 8-hydroxy-2'-deoxyguanosine (8-OH-dG) are biomarkers related to inflammation and oxidative stress. In the present study, these biomarkers were together with serum 25-hydroxyvitamin D (25(OH)D3 ) analyzed in 28 (mean age seven years) Saudi male patients with ASD...
March 1, 2018: Metabolic Brain Disease
Nilfer Sahin, Hatice Altun, Ergül Belge Kurutas, Damla Balkan
Objective: In this study, we aimed to evaluate vitamin D and vitamin D receptor levels in children with attention-deficit/hyperactivity disorder (ADHD). Patients and methods: In this cross-sectional study, a total of 80 children including 40 ADHD patients (aged 6-12 years; 28 males and 12 females) and 40 age-, sex-, and season of blood collection-matched controls (aged 6-12 years; 25 males and 15 females) were enrolled. Serum vitamin D and vitamin D receptor levels and calcium, phosphorus, and alkaline phosphatase were measured...
2018: Neuropsychiatric Disease and Treatment
Justin T van der Tas, Marlies E C Elfrink, Annemieke C Heijboer, Fernando Rivadeneira, Vincent W V Jaddoe, Henning Tiemeier, Josje D Schoufour, Henriëtte A Moll, Edwin M Ongkosuwito, Eppo B Wolvius, Trudy Voortman
OBJECTIVES: Recent literature suggested that higher vitamin D concentrations in childhood are associated with a lower prevalence of molar incisor hypomineralization (MIH). As tooth development already starts in utero, we aimed to study whether vitamin D status during foetal, postnatal and childhood periods is associated with the presence of hypomineralized second primary molars (HSPMs) and/or MIH at the age of six. METHODS: Our study was embedded in the Generation R Study, a population-based, prospective cohort from foetal life onwards in Rotterdam, the Netherlands...
March 1, 2018: Community Dentistry and Oral Epidemiology
Danish Abdul Aziz, Misha Kahlid, Fozia Memon, Kamran Sadiq
Objective: To determine clinical features and relevant laboratory investigations of patient with celiac disease (CD) and comparing classical celiac disease (CCD) with Non-diarrheal celiac disease (NDCD). Methods: This is a five years retrospective study conducted at The Aga Khan University Hospital Karachi, Pakistan from January 2010 to December 2015, enrolling children from one year to 15 years of either gender diagnosed as celiac disease in accordance with revised ESPGHAN criteria...
November 2017: Pakistan Journal of Medical Sciences Quarterly
Juliana Araujo Teixeira, Teresa Gontijo Castro, Cameron C Grant, Clare R Wall, Ana Lúcia da Silva Castro, Rossana Pulcineli Vieira Francisco, Sandra Elisabete Vieira, Silvia Regina Dias Medici Saldiva, Dirce Maria Marchioni
BACKGROUND: Women's health during their reproductive years and whilst pregnant has implications for their children's health, both in utero and during childhood. Associations of women's pre-pregnancy dietary patterns (DP) with maternal socio-demographic characteristics and nutrient intake were investigated in ProcriAr cohort study in São Paulo/Brazil, 2012. METHODS: The DPs of 454 women were investigated by principal component factor analysis, using dietary information from a validated 110-item food frequency questionnaire...
March 1, 2018: BMC Public Health
Manuel Föcker, Jochen Antel, Corinna Grasemann, Dagmar Führer, Nina Timmesfeld, Dana Öztürk, Triinu Peters, Anke Hinney, Johannes Hebebrand, Lars Libuda
BACKGROUND: Depression is a significant health and economic burden worldwide affecting not only adults but also children and adolescents. Current treatment options for this group are scarce and show moderate effect sizes. There is emerging evidence that dietary patterns and specific nutritional components might play a role in the risk for developing depression. This study protocol focusses on the role of vitamin D which is for long known to be relevant for calcium and phosphorous homeostasis and bone health but might also impact on mental health...
March 1, 2018: BMC Psychiatry
Christian Lerch, Rukshana Shroff, Mandy Wan, Lesley Rees, Helen Aitkenhead, Ipek Kaplan Bulut, Daniela Thurn, Aysun Karabay Bayazit, Anna Niemirska, Nur Canpolat, Ali Duzova, Karolis Azukaitis, Ebru Yilmaz, Fatos Yalcinkaya, Jerome Harambat, Aysel Kiyak, Harika Alpay, Sandra Habbig, Ariane Zaloszyc, Oguz Soylemezoglu, Cengiz Candan, Alejandra Rosales, Anette Melk, Uwe Querfeld, Maren Leifheit-Nestler, Anja Sander, Franz Schaefer, Dieter Haffner
Background: We investigated the effects of nutritional vitamin D supplementation on markers of bone and mineral metabolism, i.e. serum levels of fibroblast growth factor 23 (FGF23), Klotho, bone alkaline phosphatase (BAP) and sclerostin, in two cohorts with chronic kidney disease (CKD). Methods: In all, 80 vitamin D-deficient children were selected: 40 with mild to moderate CKD from the ERGO study, a randomized trial of ergocalciferol supplementation [estimated glomerular filtration rate (eGFR) 55 mL/min/1...
February 21, 2018: Nephrology, Dialysis, Transplantation
Janne Anita Kvammen, Rut Anne Thomassen, Mari Borge Eskerud, Jarle Rugtveit, Christine Henriksen
OBJECTIVES AND STUDY: To study micronutrient status and nutritional intake from complementary feeding in children on a cows' milk exclusion (CME) diet. METHODS: Fifty-seven children with cows' milk allergy, aged < 2 years, were included in a cross-sectional study. Blood was analysed for micronutrient status. Complementary feeding was defined as all solids and liquids except of breastmilk, and assessed by 3-day food diary. The results were analysed according to three feeding patterns: mainly breastfed (mBF), partially breastfed (pBF) and no breastmilk group (nBM)...
February 23, 2018: Journal of Pediatric Gastroenterology and Nutrition
Linda S Greene-Finestone, Didier Garriguet, Stephen Brooks, Kellie Langlois, Susan J Whiting
Introduction: There is evidence that 25-hydroxyvitamin D levels are lower in overweight and obese youth. This study examined the relationship between weight status and 25-hydroxyvitamin D, while controlling for confounders, in Canadian youth. Methods: Plasma 25-hydroxyvitamin D from subjects aged 6 to 17 years from the Canadian Health Measures Survey cycles 1 (2007 to 2009) and 2 (2009 to 2011) was used. Sex-specific multiple linear regression and logistic regressions examined the relationship of overweight and obesity (body mass index ≥ 85th percentile) with 25-hydroxyvitamin D levels and the odds of 25-hydroxyvitamin D <40 nmol/L and <50 nmol/L...
November 2017: Paediatrics & Child Health
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