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https://www.readbyqxmd.com/read/28050518/revitalization-of-an-immature-permanent-mandibular-molar-with-a-necrotic-pulp-using-platelet-rich-fibrin-a-case-report
#1
Dayalan Subash, Krishnamma Shoba, Shibu Aman, Srinivasan Kumar Indu Bharkavi
Any insult to the pulp during its development causes cessation of dentin formation and root growth. Pulpal status and degree of root development are the decisive factors in the treatment approach. Various treatment options have been tried like surgery with root-end sealing, calcium hydroxide-apexification, placement of apical plug and regenerative endodontic procedures to induce apexogenesis. An ideal scenario for a necrosed tooth with immature root would be continued root development coupled with regeneration of pulp tissue...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28043087/long-term-treatment-outcomes-in-immature-permanent-teeth-by-revascularisation-using-mta-and-gic-as-canal-sealing-materials-a-retrospective-study
#2
Chufang Peng, Yuan Yang, Yuming Zhao, He Liu, Zheng Xu, Dianhong Zhao, Man Qin
BACKGROUND: Pulp revascularisation with MTA sealing has been accepted as an alternative treatment for non-vital immature permanent teeth. Successful revascularisation cases with GIC sealing were also reported, but lack of long-term researches. AIM: To evaluate long-term outcomes of revascularisation using MTA and GIC as canal-sealing materials in non-vital immature permanent teeth. DESIGN: Clinical and radiographic data of 60 non-vital immature permanent teeth treated with revascularisation (36...
January 2, 2017: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/27982227/effects-of-zoledronic-acid-on-orthodontic-tooth-movement-in-rats
#3
Marcel Durante Brunet, Cristiano Miranda de Araujo, Aline Cristina Batista Rodrigues Johann, Elisa Souza Camargo, Orlando Motohiro Tanaka, Odilon Guariza
The purpose of this study was to assess the effects of the administration of zoledronic acid (ZA) during orthodontic movement in rats. A hundred and twenty male Wistar rats were applied force of 30 cN with spring closed nickel-titanium to move the upper right first molar to mesial. In the Control Movement group (CM), only tooth movement was performed; the Control Acid Zoledronic group (CAZ) received a single dose (0.1 mg/kg) of ZA; the Experimental Acid Zoledronic group (EAZ) received a single dose (0.1 mg/kg) one week prior to the start of tooth movement; and the Control Without movement group (CWM) that received no drug and without application of tooth movement...
September 2016: Brazilian Dental Journal
https://www.readbyqxmd.com/read/27973697/enhanced-regeneration-potential-of-mobilized-dental-pulp-stem-cells-from-immature-teeth
#4
Hidenori Nakayama, Koichiro Iohara, Yuki Hayashi, Yuta Okuwa, Kurita Kenichi, Misako Nakashima
OBJECTIVES: We have previously demonstrated that dental pulp stem cell (DPSCs) isolated from mature teeth by granulocyte-colony stimulating factor (G-CSF)-induced mobilization method can enhance angiogenesis/vasculogenesis and improve pulp regeneration when compared with colony-derived DPSCs. However, the efficacy of this method in immature teeth with root-formative stage has never been investigated. Therefore, the aim of this study is to examine the stemness, biological characteristics and regeneration potential in mobilized-DPSCs compared with colony-derived DPSCs from immature teeth...
December 14, 2016: Oral Diseases
https://www.readbyqxmd.com/read/27956902/vitamin-d-effects-on-osteoblastic-differentiation-of-mesenchymal-stem-cells-from-dental-tissues
#5
Francesca Posa, Adriana Di Benedetto, Graziana Colaianni, Elisabetta A Cavalcanti-Adam, Giacomina Brunetti, Chiara Porro, Teresa Trotta, Maria Grano, Giorgio Mori
1α,25-Dihydroxyvitamin D3 (1,25(OH)2D3), the active metabolite of vitamin D (Vit D), increases intestinal absorption of calcium and phosphate, maintaining a correct balance of bone remodeling. Vit D has an anabolic effect on the skeletal system and is key in promoting osteoblastic differentiation of human Mesenchymal Stem Cells (hMSCs) from bone marrow. MSCs can be also isolated from the immature form of the tooth, the dental bud: Dental Bud Stem Cells (DBSCs) are adult stem cells that can effectively undergo osteoblastic differentiation...
2016: Stem Cells International
https://www.readbyqxmd.com/read/27955921/clinical-and-radiographic-outcomes-in-immature-permanent-necrotic-evaginated-teeth-treated-with-regenerative-endodontic-procedures
#6
Ling Li, Yihuai Pan, Liqin Mei, Jun Li
INTRODUCTION: Regenerative endodontics is a promising alternative treatment for immature permanent teeth with necrotic dental pulp. The present study assessed the time to resolution of clinical symptoms and radiographic changes in root dimensions in immature permanent necrotic teeth with dens evaginatus. METHODS: In this prospective study, clinical and radiographic data were collected for 20 teeth with dens evaginatus treated with a revascularization protocol for 1 year...
December 9, 2016: Journal of Endodontics
https://www.readbyqxmd.com/read/27883188/structural-organization-and-tooth-development-in-a-homo-aff-erectus-juvenile-mandible-from-the-early-pleistocene-site-of-garba-iv-at-melka-kunture-ethiopian-highlands
#7
Clément Zanolli, M Christopher Dean, Yared Assefa, Priscilla Bayle, José Braga, Silvana Condemi, Metasebia Endalamaw, Blade Engda Redae, Roberto Macchiarelli
OBJECTIVES: The immature partial mandible GAR IVE from the c. 1.7 Ma old Garba IV site at Melka Kunture (Upper Awash Basin, Ethiopia), the earliest human representative from a mountain-like environment, represents one of the oldest early Homo specimens bearing a mixed dentition. Following its first description (Condemi, ), we extended the analytical and comparative record of this specimen by providing unreported details about its inner morphology, tooth maturational pattern and age at death, crown size, and tooth tissue proportions...
November 24, 2016: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/27882250/apical-revascularization-after-delayed-tooth-replantation-an-unusual-case
#8
Marília Pacífico Lucisano, Paulo Nelson-Filho, Lea Assed Bezerra Silva, Raquel Assed Bezerra Silva, Fabricio Kitazono de Carvalho, Alexandra Mussolino de Queiroz
The aim of this paper is to present the clinical and radiological outcome of the treatment involving a delayed tooth replantation after an avulsed immature permanent incisor, with a follow-up of 1 year and 6 months. An 8-year-old boy was referred after dental trauma that occurred on the previous day. The permanent maxillary right central incisor (tooth 11) had been avulsed. The tooth was hand-held during endodontic therapy and an intracanal medication application with calcium hydroxide-based paste was performed...
2016: Case Reports in Dentistry
https://www.readbyqxmd.com/read/27805884/root-canal-filling-after-revascularization-revitalization
#9
Hugo Plascencia, Álvaro Cruz, Mariana Díaz, Ana Laura Jiménez, Rodrigo Solís, Cesar Bernal
INTRODUCTION: Revascularization/revitalization therapy is considered an alternative procedure for management of teeth with an immature apex and necrotic pulp, mainly when root development is interrupted in the early phases of formation. However, this clinical treatment protocol should be considered a permanent procedure? METHOD: A maxillary central incisor with a previous and successful RR treatment was intentionally filled with a biocompatible material with the periapical tissues due to the patient's lack of adherence to the follow-up protocol...
2016: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/27797725/morphology-and-distribution-of-taste-papillae-and-oral-denticles-in-the-developing-oropharyngeal-cavity-of-the-bamboo-shark-chiloscyllium-punctatum
#10
Carla J L Atkinson, Kyle J Martin, Gareth J Fraser, Shaun P Collin
Gustation in sharks is not well understood, especially within species that ingest food items using suction. This study examines the morphological and immunohistochemical characterisation of taste papillae and oral denticles in the oropharynx of the brown-banded bamboo shark Chiloscyllium punctatum and compares their distribution during development. Taste papillae of C. punctatum are located throughout the oropharyngeal region and are most concentrated on the oral valves (2125-3483 per cm(2) in embryos; 89-111 per cm(2) in mature adults) close to the tooth territories...
December 15, 2016: Biology Open
https://www.readbyqxmd.com/read/27790270/vital-pulp-therapy-of-a-symptomatic-immature-permanent-molar-with-long-term-success
#11
Sedigheh Sabbagh, Alireza Sarraf Shirazi, Mohammad Jafar Eghbal
Vital pulp therapy (VPT) is the preferred conservative treatment for preservation of symptomatic pulps in immature permanent teeth. The present case report summarizes VPT of an immature permanent molar with irreversible pulpitis associated with apical periodontitis in a 9-year-old boy. Cervical pulpotomy was performed and radicular pulp stumps were covered with calcium-enriched mixture (CEM) cement; the tooth was then restored with stainless steel crown. After a 50-month follow-up period, the pulpotomized molar was clinically functional and asymptomatic...
2016: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/27790081/regenerative-dentistry-animal-model-for-regenerative-endodontology
#12
Nisarat Ruangsawasdi, Matthias Zehnder, Raphael Patcas, Chafik Ghayor, Franz E Weber
BACKGROUND: Ectopic tissue has been observed frequently in human root canal specimens when cell homing studies were performed at the dorsum of rodents. In contrast, pulp-like tissue formed when immature teeth were implanted on top of the rat calvaria. It was surmised, yet not tested, that the implantation site might affect tissue ingrowth. METHODS: Four root sections from human immature molars cleaned with 5% sodium hypochlorite (NaOCl) followed by 17% ethylenediaminetetraacetic acid (EDTA) were implanted per rat (n = 5)...
September 2016: Transfusion Medicine and Hemotherapy
https://www.readbyqxmd.com/read/27776880/guided-autotransplantation-of-teeth-a-novel-method-using-virtually-planned-3-dimensional-templates
#13
Georg D Strbac, Albrecht Schnappauf, Katharina Giannis, Michael H Bertl, Andreas Moritz, Christian Ulm
INTRODUCTION: The aim of this study was to introduce an innovative method for autotransplantation of teeth using 3-dimensional (3D) surgical templates for guided osteotomy preparation and donor tooth placement. METHODS: This report describes autotransplantation of immature premolars as treatment of an 11-year-old boy having suffered severe trauma with avulsion of permanent maxillary incisors. This approach uses modified methods from guided implant surgery by superimposition of Digital Imaging and Communications in Medicine files and 3D data sets of the jaws in order to predesign 3D printed templates with the aid of a fully digital workflow...
December 2016: Journal of Endodontics
https://www.readbyqxmd.com/read/27762658/effects-of-stem-cell-factor-on-cell-homing-during-functional-pulp-regeneration-in-human-immature-teeth
#14
Nisarat Ruangsawasdi, Matthias Zehnder, Raphael Patcas, Chafik Ghayor, Barbara Siegenthaler, Bebeka Gjoksi, Franz E Weber
Conventional root canal treatment in immature permanent teeth can lead to early tooth loss in children because root formation is discontinued. We investigated whether the stem cell factor (SCF) could facilitate cell homing in the pulpless immature root canal and promote regeneration of a functional pulp. In vitro, human mesenchymal stem cells (hMSCs) were exposed to SCF at various concentrations for assessing cell migration, proliferation, and differentiation toward odonto/osteoblasts by 3D-chemotaxis slides, WST-1 assay, and alkaline phosphatase activity, respectively...
November 22, 2016: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/27701354/a-new-legskate-sinobatis-andamanensis-rajiformes-anacanthobatidae-%C3%A2-from-the-andaman-sea-northeastern-indian-ocean
#15
Peter R Last, Somchai Bussarawit
A new legskate, Sinobatis andamanensis sp. nov. is described from a small collection of specimens taken off Phuket (Thailand) during an exploratory survey of the Andaman Sea. It is the first species of Sinobatis and the only legskate known from the northern Indian Ocean. Sinobatis andamanensis sp. nov. has an especially long and narrowly pointed snout (preorbital length exceeding 23% TL) with an interorbital distance 7-9.5 in snout length (up to 6.7 in other Sinobatis species). Molecular data are unavailable for most members of the genus, but based on morphology it shares with S...
September 14, 2016: Zootaxa
https://www.readbyqxmd.com/read/27617375/regenerative-endodontic-treatment-versus-apical-plug-in-immature-teeth-three-year-follow-up
#16
COMPARATIVE STUDY
Saeed Asgary, Mahta Fazlyab, Ali Nosrat
This report compares and evaluates the treatment outcomes of regenerative endodontic treatment and apical plug as two accepted treatment protocols in a pair of necrotic immature maxillary central incisors of a 12-year old female. The patient was referred complaining of a dull pain and swelling in her upper lip area. She had a history of trauma to the anterior maxilla two years earlier. Both teeth were clinically diagnosed with pulp necrosis and periapical radiographs revealed that separate periapical radiolucent lesions surrounded the immature apices of both teeth...
2016: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/27576211/regenerative-endodontic-procedures-for-traumatized-teeth-after-horizontal-root-fracture-avulsion-and-perforating-root-resorption
#17
Tarek Mohamed A Saoud, Sonali Mistry, Bill Kahler, Asgeir Sigurdsson, Louis M Lin
INTRODUCTION: Traumatic injury to the teeth can cause horizontal root fractures and inflammatory root resorptions (external and internal). Traditionally, traumatized teeth with horizontal root fractures resulting in pulp necrosis and inflammatory root resorptions are treated with conventional root canal therapy. METHODS: A 15-year-old boy had a history of traumatic injury to mature tooth #8 resulting in horizontal root fracture and pulp necrosis of the coronal fragment...
October 2016: Journal of Endodontics
https://www.readbyqxmd.com/read/27563191/mineral-trioxide-aggregate-apexification-a-novel-approach
#18
Aamir Rashid Purra, Fayaz Ahmed Ahangar, Sachin Chadgal, Riyaz Farooq
The treatment of choice for necrotic teeth with immature root is apexification, which is induction of apical closure to produce more favorable conditions for conventional root canal filling. The most commonly advocated medicament is calcium hydroxide although recently considerable interest has been expressed in the use of mineral trioxide aggregate (MTA). MTA offers the option of a two-visit apexification procedure so that the fragile tooth can be restored immediately. However, difficulty in placing the material in the wide apical area requires the use of an apical matrix...
July 2016: Journal of Conservative Dentistry: JCD
https://www.readbyqxmd.com/read/27554379/management-of-coronal-discolouration-following-a-regenerative-endodontic-procedure-in-a-maxillary-incisor
#19
Giselle D'Mello, Luke Moloney
Pulpal necrosis and infection in an immature anterior tooth subsequent to traumatic injury is a challenging situation. Regenerative endodontics, resulting in continued development of the tooth, provides a biological response to this clinical challenge. Regenerative endodontic procedures require disinfection of the infected root canal and sealing of the pulp canal space. Mineral trioxide aggregate (MTA) provides a good seal, is biocompatible, and allows the formation of a hard tissue to occur within the root canal...
August 24, 2016: Australian Dental Journal
https://www.readbyqxmd.com/read/27504409/effect-of-calcium-hydroxide-chlorhexidine-digluconate-and-camphorated-monochlorophenol-on-the-sealing-ability-of-biodentine-apical-plug
#20
Aastha Arora Srivastava, Harshit Srivastava, Ashwini B Prasad, Deepak Raisingani, Dileep Soni
INTRODUCTION: Teeth with immature apex are managed by establishing an apical plug using various materials and techniques. However, the use of previously placed intracanal medicament may affect the sealing ability of permanent filling material used as an apical plug. AIM: To evaluate the effect of removal of previously placed Calcium Hydroxide, Chlorhexidine Digluconate and Camphorated Monochlorophenol as an intracanal medicament on the sealing ability of the Biodentine as an apical plug...
June 2016: Journal of Clinical and Diagnostic Research: JCDR
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