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Schema therapy

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https://www.readbyqxmd.com/read/28439238/rechallenge-to-carboplatin-in-children-with-low-grade-glioma-and-carboplatin-hypersensitivity-reactions
#1
Antonio Ruggiero, Daniela Rizzo, Martina Catalano, Palma Maurizi, Stefano Mastrangelo, Giorgio Attinà, Riccardo Riccardi
Background: Carboplatin based regimens have demonstrated activity in pediatric patients with low grade gliomas (LGG). However, carboplatin hypersensitivity reactions (CHRs) may be a major problem leading to premature cessation of an effective therapy. The objectives of this study were to describe the prevalence, characteristics and management of CHR. Methods: We performed a retrospective review of children with LGG treated between January 1994 and July 2015 with carboplatin and vincristine who had a documented CHR...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28434091/continued-bullying-victimization-in-adolescents-maladaptive-schemas-as-a-mediational-mechanism
#2
Esther Calvete, Liria Fernández-González, Joaquín M González-Cabrera, Manuel Gámez-Guadix
Bullying victimization in adolescence is a significant social problem that can become persistent over time for some victims. However, there is an overall paucity of research examining the factors that contribute to continued bullying victimization. Schema therapy proposes a model that can help us understand why bullying victimization can be persistent for some victims. This study examines the role of maladaptive schemas, the key concept in schema therapy, as a mechanism of continued bullying victimization. The hypothesis was that maladaptive schemas of rejection mediate the predictive association between victimization in both the family and at school and future bullying victimization...
April 22, 2017: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/28429623/schema-therapy-for-personality-disorders-in-older-adults-a-multiple-baseline-study
#3
Arjan C Videler, Sebastiaan P J van Alphen, Rita J J van Royen, Christina M van der Feltz-Cornelis, Gina Rossi, Arnoud Arntz
OBJECTIVE: No studies have been conducted yet into the effectiveness of treatment of personality disorders in later life. This study is a first test of the effectiveness of schema therapy for personality disorders in older adults. METHOD: Multiple-baseline design with eight cluster C personality disorder patients, with a mean age of   69. After a baseline phase with random length, schema therapy was given during the first year, followed by follow-up sessions during six months...
April 21, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28423782/developing-a-manually-annotated-corpus-of-clinical-letters-for-breast-cancer-patients-on-routine-follow-up
#4
Graham Pitson, Patricia Banks, Lawrence Cavedon, Karin Verspoor
This paper introduces the annotation schema and annotation process for a corpus of clinical letters describing the disease course and treatment of oestrogen receptor positive breast cancer patients, after completion of primary surgery and radiotherapy treatment. Concepts related to therapy, clinical signs, and recurrence, as well as relationships linking these, are identified and annotated in 200 letters. This corpus will provide the basis for development of natural language processing tools for automatic extraction of key clinical factors from such letters...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28413184/risk-of-ischemic-stroke-in-patients-with-non-valvular-atrial-fibrillation-not-receiving-oral-anticoagulants%C3%A3-korean-nationwide-population-based-study
#5
Si-Hyuck Kang, Eue-Keun Choi, Kyung-Do Han, So-Ryoung Lee, Woo-Hyun Lim, Myung-Jin Cha, Youngjin Cho, Il-Young Oh, Seil Oh
BACKGROUND: Atrial fibrillation, the most common cardiac arrhythmia, is associated with an elevated thromboembolic risk, including ischemic stroke. Guidelines recommend the stratification of individual stroke risk and tailored antithrombotic therapy. This study investigated the demographics, comorbidities, and prognosis of non-valvular AF (NVAF) in Korean patients.Methods and Results:We extracted data on 10,846 patients with newly diagnosed NVAF who were naïve to oral anticoagulants from the National Health Insurance Service-National Sample Cohort...
April 12, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28409168/a-comparative-study-of-mindfulness-efficiency-based-on-islamic-spiritual-schemes-and-group-cognitive-behavioral-therapy-on-reduction-of-anxiety-and-depression-in-pregnant-women
#6
Elahe Aslami, Ahmad Alipour, Fatemeh Sadat Najib, Alireza Aghayosefi
BACKGROUND: Anxiety and depression during the pregnancy period are among the factors affecting the pregnancy undesirable outcomes and delivery. One way of controlling anxiety and depression is mindfulness and cognitive behavioral therapy. The purpose of this study was to compare the efficiency of mindfulness based on the Islamic-spiritual schemas and group cognitive behavioral therapy on reduction of anxiety and depression in pregnant women. METHODS: The research design was semi-experimental in the form of pretest-posttest using a control group...
April 2017: International Journal of Community Based Nursing and Midwifery
https://www.readbyqxmd.com/read/28406648/mechanisms-of-change-in-cognitive-therapy-for-major-depressive-disorder-in-the-community-mental-health-setting
#7
Paul Crits-Christoph, Robert Gallop, Caroline K Diehl, Seohyun Yin, Mary Beth Connolly Gibbons
OBJECTIVE: This study examined the relation of change in theory-relevant cognitive variables to depressive symptom change over the course of cognitive therapy, as well as the specificity of change mechanisms to cognitive therapy as compared with dynamic therapy. METHOD: There were 237 adult outpatients who were randomized to either cognitive (n = 119) or dynamic (n = 118) therapy for major depressive disorder in a community mental health setting. Assessments of compensatory skills (Ways of Responding Community Version and Self-Report Version), dysfunctional attitudes (Dysfunctional Attitudes Scale), and depressogenic schemas (Psychological Distance Scaling Task) were obtained at baseline and months 1, 2, and 5 following baseline...
April 13, 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28399975/survey-of-health-care-worker-knowledge-about-childhood-tuberculosis-in-high-burden-centers-in-botswana
#8
T Arscott-Mills, L Masole, R Ncube, A P Steenhoff
BACKGROUND: Quantifying health care workers' (HCWs') knowledge about tuberculosis (TB) informs educational interventions. We assessed HCWs' knowledge about childhood TB in Botswana. METHODS: Semi-structured interviews were conducted with HCWs at 46 sites around Botswana using a piloted instrument. Transcripts were double-coded using a coding schema. Discrepancies were resolved by consensus and a systematic thematic analysis was performed. RESULTS: The sites (42 clinics and 4 hospitals) were urban (n = 9, 20%), semi-urban (n = 10, 22%) and rural (n = 27, 58%)...
May 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28393336/-using-the-cognitive-behavioral-therapy-to-improve-the-mental-health-of-women-with-breast-cancer
#9
Li-Hung Lee, Yu-Ping Lai, Cheng-I Yang
Previous studies have shown that patients with breast cancer may suffer from symptoms of psychological distress, such as: depression, anxiety, insomnia, and chronic fatigue. Nurses are expected to offer physical and mental support to these patients. Cognitive behavior therapy (CBT) is commonly used in psychiatry as well as in the treatment of patients with breast cancer. CBT is believed to reduce mental distress in patients by changing their negative cognitive schema. The present article discusses the mental problems of patients with breast cancer and introduces the effects of using CBT on patients with breast cancer...
April 2017: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/28390442/a-first-step-toward-integrating-schema-theory-in-geriatric-psychiatry-a-delphi-study
#10
M J H Legra, F R J Verhey, S P J van Alphen
BACKGROUND: Schematherapy (ST) is an effective therapy for personality disorders (PD's) in adults, however, empirical research into ST in older adults is limited. The manifestation of schemas over the life course is unclear. Besides, long-term patterns of schemas in old age and whether schemas change during the aging process remain unknown. METHODS: We performed a Delphi study involving a group meeting of nine experts in the field of ST in older adults. RESULTS: Full consensus was achieved that schemas vary later in life, and that this is due to biopsychosocial factors...
April 9, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28389462/improved-outcomes-for-myeloid-leukemia-of-down-syndrome-a-report-from-the-children-s-oncology-group-aaml0431-trial
#11
Jeffrey W Taub, Jason N Berman, Johann K Hitzler, April D Sorrell, Norman J Lacayo, Kelley Mast, David Head, Susana Raimondi, Betsy Hirsch, Yubin Ge, Robert B Gerbing, Yi-Cheng Wang, Todd A Alonzo, Dario Campana, Elaine Coustan-Smith, Prasad Mathew, Alan S Gamis
Patients with myeloid leukemia of Down syndrome (ML-DS) have a favorable event-free survival (EFS), but experience significant treatment-related morbidity and mortality. ML-DS blast cells ex vivo have increased sensitivity to cytarabine (araC) and daunorubicin, suggesting that optimizing drug dosing may improve outcomes while reducing toxicity. The Children's Oncology Group (COG) AAML0431 trial consisted of 4 cycles of Induction and 2 cycles of Intensification therapy based on the treatment schema of the previous COG A2971 trial with several modifications...
April 7, 2017: Blood
https://www.readbyqxmd.com/read/28319789/group-schema-therapy-for-personality-disorders-a-pilot-study-for-implementation-in-acute-psychiatric-in-patient-settings
#12
Igor Nenadić, Sina Lamberth, Neele Reiss
Group schema therapy (GST) has been proposed as a novel long-term treatment programme for borderline and cluster C personality disorders. We implemented a short-term GST programme (12-15 sessions, based on the manual by Farrell and Shaw (2012), including both cognitive / behavioural and experiential interventions for in-patients (n=9) with either borderline or cluster C personality disorders (and axis I co-morbidities) treated in a (sub)acute psychiatric in-patient setting. We evaluated pre- and post-treatment self-report of maladaptive and adaptive schema modes (using the SMI) and early maladaptive schemas (YSQ-3), as well as overall symptom severity (brief symptom check list, BSCL-53-S), patient satisfaction (ZUF-8) and group climate and coherence (GCQ-S)...
February 3, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28306546/substitute-ct-generation-from-a-single-ultra-short-time-echo-mri-sequence-preliminary-study
#13
Soumya Ghose, Jason A Dowling, Robba Rai, Gary P Liney
In MR guided radiation therapy planning both MR and CT images for a patient are acquired and co-registered to obtain a tissue specific HU map. Generation of the HU map directly from the MRI would eliminate the CT acquisition and may improve radiation therapy planning. In this preliminary study of substitute CT (sCT) generation, two porcine leg phantoms were scanned using a 3D ultrashort echo time (PETRA) sequence and co-registered to corresponding CT images to build tissue specific regression models. The model was created from one co-registered CT-PETRA pair to generate the sCT for the other PETRA image...
April 21, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28285082/response-assessment-in-myeloma-practical-manual-on-consistent-reporting-in-an-era-of-dramatic-therapeutic-advances
#14
Laurent Garderet, Anita D'Souza, Paulette Jacobs, Anja van Biezen, Stefan Schönland, Nicolaus Kroeger, Curly Morris, Parameswaran Hari
The understanding and treatment of multiple myeloma (MM) have dramatically improved in recent years. However, accurate assessment of the response of myeloma to therapy and its subsequent relapse remains a difficult task. Criteria have changed over time and new parameters have recently been incorporated to evaluate minimal residual disease status. We present a practical approach to assess response and relapse/progression in myeloma in the context of its treatment. A robust reporting schema is crucial to correctly evaluate any treatment protocol and compare results across trials...
March 8, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/28275048/brain-machine-interfaces-from-basic-science-to-neuroprostheses-and-neurorehabilitation
#15
REVIEW
Mikhail A Lebedev, Miguel A L Nicolelis
Brain-machine interfaces (BMIs) combine methods, approaches, and concepts derived from neurophysiology, computer science, and engineering in an effort to establish real-time bidirectional links between living brains and artificial actuators. Although theoretical propositions and some proof of concept experiments on directly linking the brains with machines date back to the early 1960s, BMI research only took off in earnest at the end of the 1990s, when this approach became intimately linked to new neurophysiological methods for sampling large-scale brain activity...
April 2017: Physiological Reviews
https://www.readbyqxmd.com/read/28249651/symptom-burden-and-dysphagia-associated-with-osteoradionecrosis-in-long-term-oropharynx-cancer-survivors-a-cohort-analysis
#16
Angela T T Wong, Stephen Y Lai, G Brandon Gunn, Beth M Beadle, Clifton D Fuller, Martha P Barrow, Theresa M Hofstede, Mark S Chambers, Erich M Sturgis, Abdallah Sherif Radwan Mohamed, Jan S Lewin, Katherine A Hutcheson
OBJECTIVE: The purpose is to examine the relationship between mandibular osteoradionecrosis (ORN) and chronic dysphagia in long-term oropharynx cancer (OPC) survivors, and to determine the perceived symptom burden associated with ORN. MATERIALS AND METHODS: Medical records of 349 OPC patients treated with bilateral IMRT and systemic therapy were reviewed. ORN was graded using a published 4-point classification schema. Patients were considered to have chronic dysphagia if they had aspiration pneumonia, stricture or aspiration detected by fluoroscopy or endoscopy, and/or feeding tube dependence in long-term follow-up ⩾1year following radiotherapy...
March 2017: Oral Oncology
https://www.readbyqxmd.com/read/28249615/secondary-hemophagocytic-lymphohistiocytosis-in-the-setting-of-metastatic-renal-cell-carcinoma-a-case-report
#17
Monica El-Masry, Lauren Eisenbud, Minh-Ha Tran
BACKGROUND: Hemophagocytic lymphohistiocytosis is a disease process characterized by unregulated hyperactivation of the immune system associated with multiorgan involvement and high mortality rates. Early recognition is crucial and a recently validated diagnostic schema, the H-Score, may facilitate diagnosis particularly in secondary hemophagocytic lymphohistiocytosis cases. We present a patient with secondary hemophagocytic lymphohistiocytosis in association with metastatic renal cell carcinoma in whom high-dose steroid therapy induced a remarkable response...
March 2, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28244414/influence-of-fractionation-scheme-and-tumor-location-on-toxicities-after-stereotactic-body-radiation-therapy-for-large-%C3%A2-5-cm-non-small-cell-lung-cancer-a-multi-institutional-analysis
#18
Vivek Verma, Valerie K Shostrom, Weining Zhen, Mutian Zhang, Steve E Braunstein, John Holland, Christopher L Hallemeier, Matthew M Harkenrider, Adrian Iskhanian, Salma K Jabbour, Albert Attia, Percy Lee, Kyle Wang, Roy H Decker, Ronald C McGarry, Charles B Simone
PURPOSE: To describe the impact of fractionation scheme and tumor location on toxicities in stereotactic body radiation therapy (SBRT) for ≥5-cm non-small cell lung cancer (NSCLC), as part of a multi-institutional analysis. METHODS: Patients with primary ≥5-cm N0 M0 NSCLC who underwent ≤5-fraction SBRT were examined across multiple high-volume SBRT centers. Collected data included clinical/treatment parameters; toxicities were prospectively assessed at each institution according to the Common Terminology Criteria for Adverse Events...
March 15, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28238297/are-perfectionist-therapists-perfect-the-relationship-between-therapist-perfectionism-and-client-outcomes-in-cognitive-behavioural-therapy
#19
Vickie L Presley, Christopher A Jones, Elizabeth K Newton
BACKGROUND: The psychological literature suggests that therapist perfectionism is common and potentially detrimental to client recovery. Little is known about the relationship between therapist perfectionism and client outcomes. AIMS: This study aimed to measure perfectionism in High Intensity Cognitive Behavioural therapists, and establish any relationships between dimensions of therapist perfectionism, client outcomes and drop-out rates in treatment. METHOD: Thirty-six therapists took part in the study; levels of perfectionism were measured using a self-report questionnaire and these were analysed in relation to the clinical outcomes from a sample of their clients...
February 27, 2017: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/28223022/early-identification-of-mild-cognitive-impairment-using-incomplete-random-forest-robust-support-vector-machine-and-fdg-pet-imaging
#20
Shen Lu, Yong Xia, Weidong Cai, Michael Fulham, David Dagan Feng
Alzheimer's disease (AD) is the most common type of dementia and will be an increasing health problem in society as the population ages. Mild cognitive impairment (MCI) is considered to be a prodromal stage of AD. The ability to identify subjects with MCI will be increasingly important as disease modifying therapies for AD are developed. We propose a semi-supervised learning method based on robust optimization for the identification of MCI from [18F]Fluorodeoxyglucose PET scans. We extracted three groups of spatial features from the cortical and subcortical regions of each FDG-PET image volume...
February 7, 2017: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
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