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https://www.readbyqxmd.com/read/29689307/sensory-threshold-neuromuscular-electrical-stimulation-fosters-motor-imagery-performance
#1
Tiffany Corbet, Iñaki Iturrate, Michael Pereira, Serafeim Perdikis, José Del R Millán
Motor imagery (MI) has been largely studied as a way to enhance motor learning and to restore motor functions. Although it is agreed that users should emphasize kinesthetic imagery during MI, recordings of MI brain patterns are not sufficiently reliable for many subjects. It has been suggested that the usage of somatosensory feedback would be more suitable than standardly used visual feedback to enhance MI brain patterns. However, somatosensory feed-back should not interfere with the recorded MI brain pattern...
April 21, 2018: NeuroImage
https://www.readbyqxmd.com/read/29688861/examining-the-spatiotemporal-evolution-of-vaccine-refusal-nonmedical-exemptions-from-vaccination-in-california-2000-2013
#2
Paul L Delamater, Timothy F Leslie, Y Tony Yang
BACKGROUND: Vaccine hesitancy continues to be an issue throughout the United States, as numerous vaccine hesitant parents are choosing to exempt their children from school-entry vaccination requirements for nonmedical reasons, despite the safety and effectiveness of vaccines. We conduct an analysis of how vaccine refusal, measured by the use of nonmedical exemptions (based on personal or religious beliefs) from vaccination (NMEs), evolved across space and over time in California. METHODS: Using school-entry data from the California Department of Public Health, we examined NMEs for students entering kindergarten in California from 2000 to 2013...
April 24, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29687898/neuromuscular-fatigue-after-low-and-medium-frequency-electrical-stimulation-in-healthy-adults
#3
Pedro Ferreira Alves de Oliveira, João Luiz Quagliotti Durigan, Karenina Arrais Guida Modesto, Martim Bottaro, Nicolas Babault
INTRODUCTION: We studied fatigue origins induced by low-frequency pulsed current (PC) and medium frequency current (MF) neuromuscular electrical stimulation (NMES) after a clinical-like session. METHODS: Eleven healthy men randomly underwent 2 NMES sessions, PC and MF, on quadriceps muscle (15-min duration, 6-s on and 18-s off). Maximal voluntary contraction (MVC), central activation ratio (CAR), vastus lateralis electromyographic activity (EMG) and evoked contractile properties were determined before and after sessions...
April 17, 2018: Muscle & Nerve
https://www.readbyqxmd.com/read/29679248/effects-of-training-intensity-in-electromyostimulation-on-human-skeletal-muscle
#4
Toshiharu Natsume, Hayao Ozaki, Ryo Kakigi, Hiroyuki Kobayashi, Hisashi Naito
PURPOSE: High-intensity neuromuscular electrical stimulation (NMES) training can induce muscle hypertrophy at the whole muscle and muscle fiber levels. However, whether low-intensity NMES training has a similar result is unknown. This study aimed to investigate whether low-intensity NMES training could elicit muscle hypertrophy at the whole muscle and muscle fiber levels in the human skeletal muscle. METHODS: Eight untrained young males were subjected to 18 min of unilateral NMES training for 8 weeks...
April 20, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29628406/eccentric-training-combined-to-neuromuscular-electrical-stimulation-is-not-superior-to-eccentric-training-alone-for-quadriceps-strengthening-in-healthy-subjects-a-randomized-controlled-trial
#5
Claudia Ferreira Gomes da Silva, Felipe Xavier de Lima E Silva, Karoline Baptista Vianna, Gabriel Dos Santos Oliveira, Marco Aurélio Vaz, Bruno Manfredini Baroni
BACKGROUND: Both eccentric training and neuromuscular electrical stimulation (NMES) are used for quadriceps strengthening. However, the effects of these interventions combined are unclear. OBJECTIVES: To compare the effects of eccentric training combined to NMES and eccentric training alone on structure, strength, and functional performance of knee extensor muscles of healthy subjects. METHODS: This is a three-arm, single-blinded, randomized controlled trial...
March 28, 2018: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/29617180/use-of-trunk-muscle-training-and-neuromuscular-electrical-stimulation-to-reduce-pain-and-disability-in-an-older-adult-with-chronic-low-back-pain-a-case-report
#6
Jenifer M Pugliese, J Megan Sions, Teonette O Velasco, Gregory E Hicks
Among older adults, low back pain (LBP) is common, costly, and disabling. Trunk muscle training (TMT) and neuromuscular electrical stimulation (NMES) have both been found to be effective in reducing LBP, but studies among older adults have been limited. An 83-year-old female with left-sided chronic LBP participated in a randomized controlled trial consisting of supervised TMT and NMES to the paraspinal muscles two times per week for 12 weeks. She also participated in a home exercise program. At the end of the intervention, she reported reduced LBP and LBP-related disability per the modified Oswestry disability index (i...
April 4, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29574805/investigation-of-the-relationship-between-electrical-stimulation-frequency-and-muscle-frequency-response-under-submaximal-contractions
#7
Caluê Papcke, Eddy Krueger, Marcia Olandoski, Guilherme Nunes Nogueira-Neto, Percy Nohama, Eduardo Mendonça Scheeren
Neuromuscular electrical stimulation (NMES) is a common tool that is used in clinical and laboratory experiments and can be combined with mechanomyography (MMG) for biofeedback in neuroprostheses. However, it is not clear if the electrical current applied to neuromuscular tissues influences the MMG signal in submaximal contractions. The objective of this study is to investigate whether the electrical stimulation frequency influences the mechanomyographic frequency response of the rectus femoris muscle during submaximal contractions...
March 25, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29572333/risk-of-clinically-relevant-pharmacokinetic-based-drug-drug-interactions-with-drugs-approved-by-the-u-s-food-and-drug-administration-between-2013-and-2016
#8
Jingjing Yu, Zhu Zhou, Jessica Tay-Sontheimer, Rene H Levy, Isabelle Ragueneau-Majlessi
A total of 103 drugs (including 14 combination drugs) were approved by the U.S. Food and Drug Administration from 2013 to 2016. Pharmacokinetic-based drug interaction profiles were analyzed using the University of Washington Drug Interaction Database and the clinical relevance of these observations was characterized based on information from New Drug Application reviews. CYP3A was identified as a major contributor to clinical drug-drug interactions (DDIs), involved in approximately 2/3 of all interactions. Transporters (alone or with enzymes) were found to participate in about half of all interactions, although most of these were weak-to-moderate interactions...
March 23, 2018: Drug Metabolism and Disposition: the Biological Fate of Chemicals
https://www.readbyqxmd.com/read/29554013/high-frequency-neuromuscular-electrical-stimulation-increases-anabolic-signaling
#9
Joni A Mettler, Dillon M Magee, Barbara M Doucet
PURPOSE: Neuromuscular electrical stimulation (NMES) is commonly used in rehabilitation settings to increase muscle mass and strength. However, the effects of NMES on muscle growth are not clear and no human studies have compared anabolic signaling between low-frequency (LF-) and high-frequency (HF-) NMES. The purpose of this study was to determine the skeletal muscle anabolic signaling response to an acute bout of LF- and HF-NMES. METHODS: Eleven young healthy volunteers (6 men; 5 women) received an acute bout of LF- (20 Hz) and HF- (60 Hz) NMES...
March 16, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29553959/a-comparison-of-neuromuscular-electrical-stimulation-and-traditional-therapy-versus-traditional-therapy-in-patients-with-longstanding-dysphagia
#10
Jo Frost, Fiona Robinson, Judi Hibberd
PURPOSE OF REVIEW: Dysphagia in adults arises from a range of causes including acquired neurological disorders and some cancers. Previous research has suggested that treatment using neuromuscular electrical stimulation (NMES) when used in conjunction with conventional therapy is effective. This review describes the recent literature and a small prospective case series carried out in the United Kingdom. This study contributed to support National Institute of Clinical Excellence (NICE) guidance for clinicians who wish to include NMES in a rehabilitation programme for dysphagic patients, specifically with reference to safety and the impact on swallowing function of this intervention...
March 16, 2018: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/29532649/contralateral-effect-of-short-duration-unilateral-neuromuscular-electrical-stimulation-and-focal-vibration-in-healthy-subjects
#11
Marco A Minetto, Alberto Botter, Giulia Gamerro, Ilaria Varvello, Giuseppe Massazza, Rosa G Bellomo, Nicola A Maffiuletti, Raoul Saggini
BACKGROUND: The "contralateral effect" phenomenon refers to the strength gain in the opposite, untrained homonymous muscle following unilateral training. Previous studies showed that neuromuscular electrical stimulation (NMES) of the right quadriceps facilitated maximal voluntary strength and efferent neural drive of the left knee extensors, while no previous study investigated the contralateral effect elicited by focal muscle vibration. AIM: To investigate whether quadriceps NMES and focal vibration, when applied unilaterally, have the same potential to enhance the contralateral muscle strength and the associated neural drive...
March 12, 2018: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29530519/systematic-review-of-three-electrical-stimulation-techniques-for-rehabilitation-after-total-knee-arthroplasty
#12
REVIEW
Chen Yue, Xue Zhang, Yingjie Zhu, Yudong Jia, Huichao Wang, Youwen Liu
BACKGROUND: The comparative effectiveness of neuromuscular electrical stimulation (NMES), transcutaneous electrical nerve stimulation (TENS), and electroacupuncture (EA) for improving patient rehabilitation following total knee arthroplasty (TKA) is controversial. Therefore we conducted this systematic review to assess the available evidence. METHODS: The PubMed, OVID, and ScienceDirect databases were comprehensively searched and studies were selected and analyzed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations...
February 6, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29529880/intradialytic-neuromuscular-electrical-stimulation-reduces-dna-damage-in-chronic-kidney-failure-patients-a-randomized-controlled-trial
#13
Jociane Schardong, Verônica Bidinotto Brito, Thiago Dipp, Fabrício Edler Macagnan, Jenifer Saffi, Rodrigo Dm Plentz
BACKGROUND: Chronic kidney failure (CKF) patients on renal replacement therapies exhibit elevated levels of DNA lesions and this is directly related to high mortality. OBJECTIVE: This study aimed to evaluate the effect of neuromuscular electrical stimulation (NMES) on genomic damage in CKF patients on conventional hemodialysis (HD). METHODS: Twenty-one patients with CKF on HD were randomized into control (CG = 10) or neuromuscular electrical stimulation (NMESG = 11) groups...
March 12, 2018: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/29496509/can-electrical-stimulation-enhance-effects-of-a-functional-training-program-in-hospitalized-geriatric-patients
#14
Amanda Hempel Zinglersen, Malte Bjørn Halsteen, Michael Kjær, Anders Karlsen
BACKGROUND: Hospitalization of older medical patients may lead to functional decline. This study investigated whether simultaneously applied neuromuscular electrical stimulation (NMES) can enhance the effects of a functional training program in hospitalized geriatric patients. METHOD: This was a quasi-randomized controlled trial in geriatric hospitalized patients (N = 16, age = 83.1 ± 8.1 years, mean ± SD). The patients performed a simple and time efficient chair-stand based functional exercise program daily, either with (FT + NMES, N = 8) or without (FT, N = 8) simultaneous NMES to the knee extensor muscles...
February 26, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29494292/paralytic-and-non-paralytic-muscle-adaptations-to-exercise-training-vs-high-protein-diet-in-individuals-with-long-standing-spinal-cord-injury
#15
Ceren Yarar-Fisher, Keith Fl Polston, Mualla Eraslan, Kathryn Y Henley, Gizem I Kinikli, C Scott Bickel, Samuel T Windham, Amie B McLain, Robert A Oster, Marcas M Bamman
This study compares the effects of an 8-week iso-caloric high protein (HP) diet versus a combination exercise (Comb-Ex) regimen on paralytic vastus lateralis (VL) and non-paralytic deltoid muscle in individuals with long-standing spinal cord injury (SCI). Fiber type distribution, cross-sectional area (CSA), levels of translation initiation signaling proteins (Erk-1/2, Akt, p70S6K1, 4EBP1, RPS6, and FAK), and lean thigh mass were analyzed at baseline and after the 8-week interventions. A total of 11 participants (C5-T12 levels, 21...
March 1, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29457998/home-based-neuromuscular-electrical-stimulation-as-an-add-on-to-pulmonary-rehabilitation-does-not-provide-further-benefits-in-patients-with-chronic-obstructive-pulmonary-disease-a-multicenter-randomized-trial
#16
Tristan Bonnevie, Francis-Edouard Gravier, David Debeaumont, Catherine Viacroze, Jean-François Muir, Antoine Cuvelier, Marie Netchitaïlo, Anne Laure Roy, Jean Quieffin, Marie-Hélène Marques, Clément Médrinal, Johan Dupuis, Catherine Tardif
OBJECTIVE: To assess the additional effect of a home-based neuro muscular electrical stimulation (NMES) program as an add-on to pulmonary rehabilitation (PR), on functional capacity in subjects with chronic obstructive pulmonary disease (COPD). DESIGN: Single-blind, multicenter randomized trial. SETTING: Three PR centers. PARTICIPANTS: Subjects with severe to very severe COPD referred for PR (n=73; median FEV1, 1 (0...
February 16, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29451272/the-ndpk-nme-superfamily-state-of-the-art
#17
EDITORIAL
Mathieu Boissan, Uwe Schlattner, Marie-Lise Lacombe
Nucleoside diphosphate kinases (NDPK) are nucleotide metabolism enzymes encoded by NME genes (also called NM23). Given the fact that not all NME-encoded proteins are catalytically active NDPKs and that NM23 generally refers to clinical studies on metastasis, we use here NME/NDPK to denote the proteins. Since their discovery in the 1950's, NMEs/NDPKs have been shown to be involved in multiple physiological and pathological cellular processes, but the molecular mechanisms have not been fully determined. Recent progress in elucidating these underlying mechanisms has been presented by experts in the field at the 10th International Congress on the NDPK/NME/AWD protein family in October 2016 in Dubrovnik, Croatia, and is summarized in review articles or original research in this and an upcoming issue of Laboratory Investigation...
February 2018: Laboratory Investigation; a Journal of Technical Methods and Pathology
https://www.readbyqxmd.com/read/29443103/paradigms-of-lower-extremity-electrical-stimulation-training-after-spinal-cord-injury
#18
Ashraf S Gorgey, Refka E Khalil, Robert M Lester, Gary A Dudley, David R Gater
Skeletal muscle atrophy, increased adiposity and reduced physical activity are key changes observed after spinal cord injury (SCI) and are associated with numerous cardiometabolic health consequences. These changes are likely to increase the risk of developing chronic secondary conditions and impact the quality of life in persons with SCI. Surface neuromuscular electrical stimulation evoked resistance training (NMES-RT) was developed as a strategy to attenuate the process of skeletal muscle atrophy, decrease ectopic adiposity, improve insulin sensitivity and enhance mitochondrial capacity...
February 1, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29434456/does-neuromuscular-electrical-stimulation-therapy-increase-voluntary-muscle-strength-after-spinal-cord-injury-a-systematic-review
#19
Gabriel Ribeiro de Freitas, Camila Szpoganicz, Jocemar Ilha
Background: Physical therapists frequently use neuromuscular electrical stimulation (NMES) therapy in an effort to increase the voluntary strength of partially paralyzed muscles in people with spinal cord injury (SCI), but it is not clear whether this treatment is effective. Objective: To determine the effectiveness of NMES for increasing voluntary strength in the partially paralyzed muscles of people with SCI. Methods: A systematic review of scientific literature was conducted in MEDLINE, CINAHL, PEDro, ScienceDirect, and Embase...
2018: Topics in Spinal Cord Injury Rehabilitation
https://www.readbyqxmd.com/read/29434248/modulation-of-small-gtpase-activity-by-nme-proteins
#20
REVIEW
Vedrana Filić, Maja Marinović, Marko Šoštar, Igor Weber
NME proteins are reported to influence signal transduction activity of small GTPases from the Ras superfamily by diverse mechanisms in addition to their generic NDP kinase activity, which replenishes the cytoplasmic pool of GTP. Comprehensive evidence shows that NME proteins modulate the activity of Ras GTPases, in particular members of the Rho family, via binding to their major activators GEFs. Direct interaction between several NMEs and Ras GTPases were also indicated in vitro and in vivo. These modes of regulation are mainly independent of the NME's kinase activity...
February 12, 2018: Laboratory Investigation; a Journal of Technical Methods and Pathology
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