keyword
MENU ▼
Read by QxMD icon Read
search

High altitude

keyword
https://www.readbyqxmd.com/read/28086991/does-waterfall-aerosol-influence-mucosal-immunity-and-chronic-stress-a-randomized-controlled-clinical-trial
#1
Carina Grafetstätter, Martin Gaisberger, Johanna Prossegger, Markus Ritter, Predrag Kolarž, Christina Pichler, Josef Thalhamer, Arnulf Hartl
BACKGROUND: The specific microclimate of alpine waterfalls with high levels of ionized water aerosols has been suggested to trigger beneficial immunological and psychological effects. In the present three-armed randomized controlled clinical study, we focused on effects on (i) immunological reagibility, on (ii) physiological stress responses, and on (iii) stress-related psychological parameters. METHODS: People with moderate to high stress levels (n = 65) spent an active sojourn with daily hiking tours in the National Park Hohe Tauern (Großkirchheim, Austria)...
January 13, 2017: Journal of Physiological Anthropology
https://www.readbyqxmd.com/read/28081144/digital-health-tracking-physiomes-and-activity-using-wearable-biosensors-reveals-useful-health-related-information
#2
Xiao Li, Jessilyn Dunn, Denis Salins, Gao Zhou, Wenyu Zhou, Sophia Miryam Schüssler-Fiorenza Rose, Dalia Perelman, Elizabeth Colbert, Ryan Runge, Shannon Rego, Ria Sonecha, Somalee Datta, Tracey McLaughlin, Michael P Snyder
A new wave of portable biosensors allows frequent measurement of health-related physiology. We investigated the use of these devices to monitor human physiological changes during various activities and their role in managing health and diagnosing and analyzing disease. By recording over 250,000 daily measurements for up to 43 individuals, we found personalized circadian differences in physiological parameters, replicating previous physiological findings. Interestingly, we found striking changes in particular environments, such as airline flights (decreased peripheral capillary oxygen saturation [SpO2] and increased radiation exposure)...
January 2017: PLoS Biology
https://www.readbyqxmd.com/read/28080218/temperature-dependence-of-multiple-sclerosis-mortality-rates-in-the-united-states
#3
Hongbing Sun
BACKGROUND: It is well known that multiple sclerosis (MS) patients are very sensitive to heat events. However, how MS patients respond to the significant temperature difference between the high- and low-latitude regions is not understood. OBJECTIVE: The goal is to identify the primary factor responsible for the fact that MS mortality rates of the United States is more than three times higher in the northern states than in the southern states. METHODS: Correlation coefficients between the age-adjusted mortality rate of MS as the underlying cause of death and the state average temperature, altitude, latitude, duration of sunshine hours, and solar radiation in the 48 contiguous states were compared...
January 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28077391/acclimation-to-hypoxia-increases-carbohydrate-use-during-exercise-in-high-altitude-deer-mice
#4
Daphne S Lau, Alex D Connaty, Sajeni Mahalingam, Nastashya Wall, Zachary A Cheviron, Jay F Storz, Graham R Scott, Grant B McClelland
The low oxygen experienced at high altitude is a significant challenge to effective aerobic locomotion, as it requires sustained tissue oxygen delivery in addition to the appropriate allocation of metabolic substrates. Here we test whether high- and low-altitude deer mice (Peromyscus maniculatus) have evolved different acclimation responses to hypoxia with respect to muscle metabolism and fuel use during submaximal exercise. Using F1-generation high- and low-altitude deer mice that were born and raised in common conditions, we assessed 1) fuel use during exercise, 2) metabolic enzyme activities, and 3) gene expression for key transporters and enzymes in the gastrocnemius...
January 11, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28075653/serum-creatine-kinase-elevations-in-ultramarathon-runners-at-high-altitude
#5
Danielle Magrini, Morteza Khodaee, Inigo San Millan, Tamara Hew-Butler, Aaron J Provance
OBJECTIVES: Creatine kinase (CK) is a sensitive enzyme marker for muscle damage in athletes. Elevated CK levels have been reported in many endurance physical activities. The consequence and possible long-term sequela of the CK elevation in athletes is unknown. There is a paucity of literature stating actual numerical values of CK associated with competing in an ultramarathon with extreme environmental conditions. Our hypothesis was that the serum CK levels increase significantly as a result of running a 161km ultramarathon at high altitude...
January 11, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28074016/cari-7a-development-and-validation
#6
Kyle Copeland
Aircrew members can be exposed to higher annual doses of natural ionizing radiation than members of the general population in most parts of the world. The principal ionizing radiation to which they are exposed is galactic cosmic radiation (GCR). Among the particles present in the primary spectrum are heavy ions: relativistic nuclei of lithium and heavier elements. These ions have very high radiation weighting factors and can contribute significantly to the effective dose at altitudes above the Pfotzer maximum...
January 10, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/28073099/golden-root-a-wholesome-treat-of-immunity
#7
REVIEW
Kunjan Khanna, K P Mishra, Lilly Ganju, Shashi Bala Singh
Rhodiola is native to the high altitude regions of Asia, Europe and Northern Hemisphere. It has a long history of use as a medicinal plant in various ailments, boosting immunity, increasing energy and mental capacity. It is also known as "Adaptogen" to help the body to adapt and resist stress. The part of the plant, which is used for medicinal values, is rhizome, which is an underground stem. The rhizome contains mainly salidroside, rosin, rosavin and p-tyrosol. There are many studies, which have reported the effects of Rhodiola spp...
January 7, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28070978/testing-for-local-adaptation-and-evolutionary-potential-along-altitudinal-gradients-in-rainforest-drosophila-beyond-laboratory-estimates
#8
Eleanor K O'Brien, Megan Higgie, Alan Reynolds, Ary A Hoffmann, Jon R Bridle
Predicting how species will respond to the rapid climatic changes predicted this century is an urgent task. Species distribution models (SDMs) use the current relationship between environmental variation and species' abundances to predict the effect of future environmental change on their distributions. However, two common assumptions of SDMs are likely to be violated in many cases: (i) that the relationship of environment with abundance or fitness is constant throughout a species' range and will remain so in future and (ii) that abiotic factors (e...
January 10, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28068392/vegetation-changes-in-the-permafrost-regions-of-the-qinghai-tibetan-plateau-from-1982-2012-different-responses-related-to-geographical-locations-and-vegetation-types-in-high-altitude-areas
#9
Zhiwei Wang, Qian Wang, Xiaodong Wu, Lin Zhao, Guangyang Yue, Zhuotong Nan, Puchang Wang, Shuhua Yi, Defu Zou, Yu Qin, Tonghua Wu, Jianzong Shi
The Qinghai-Tibetan Plateau (QTP) contains the largest permafrost area in a high-altitude region in the world, and the unique hydrothermal environments of the active layers in this region have an important impact on vegetation growth. Geographical locations present different climatic conditions, and in combination with the permafrost environments, these conditions comprehensively affect the local vegetation activity. Therefore, the responses of vegetation to climate change in the permafrost region of the QTP may be varied differently by geographical location and vegetation condition...
2017: PloS One
https://www.readbyqxmd.com/read/28063399/sleep-quality-among-elderly-high-altitude-dwellers-in-ladakh
#10
Ryota Sakamoto, Kiyohito Okumiya, Tsering Norboo, Norboo Tsering, Takayoshi Yamaguchi, Mitsuhiro Nose, Shinya Takeda, Toshihiro Tsukihara, Motonao Ishikawa, Shun Nakajima, Taizo Wada, Michiko Fujisawa, Hissei Imai, Yasuko Ishimoto, Yumi Kimura, Eriko Fukutomi, Wenling Chen, Kuniaki Otsuka, Kozo Matsubayashi
It has been already known that people who temporarily stay at high altitude may develop insomnia as a symptom of acute mountain sickness. However, much less is known about people living at high altitude. The aim of this study was to determine the effect of high altitude environment on sleep quality for the elderly who have been living at high altitude for their whole lives. A cross-sectional study was conducted in Domkhar valley at altitudes of 2800-4200m, Ladakh. Sleep quality was assessed using Insomnia Severity Index (ISI)...
December 29, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/28062411/mapping-morphological-shape-as-a-high-dimensional-functional-curve
#11
Guifang Fu, Mian Huang, Wenhao Bo, Han Hao, Rongling Wu
Detecting how genes regulate biological shape has become a multidisciplinary research interest because of its wide application in many disciplines. Despite its fundamental importance, the challenges of accurately extracting information from an image, statistically modeling the high-dimensional shape and meticulously locating shape quantitative trait loci (QTL) affect the progress of this research. In this article, we propose a novel integrated framework that incorporates shape analysis, statistical curve modeling and genetic mapping to detect significant QTLs regulating variation of biological shape traits...
January 6, 2017: Briefings in Bioinformatics
https://www.readbyqxmd.com/read/28061780/rhodiola-crenulata-extract-counteracts-the-effect-of-hypobaric-hypoxia-in-rat-heart-via-redirection-of-the-nitric-oxide-and-arginase-1-pathway
#12
Shih-Wei Hsu, Tsu-Chung Chang, Yu-Kuan Wu, Kuen-Tze Lin, Li-Shian Shi, Shih-Yu Lee
BACKGROUND: Rhodiola crenulata is traditionally used as a folk medicine in Tibet for preventing high-altitude illnesses, including sudden cardiac death (SCD). The cardio-protective effects of Rhodiola crenulata root extract (RCE) against hypoxia in vivo have been recently confirmed. However, the way in which RCE produces these effects remains unclear. The present study is designed to confirm the protective effects of RCE on the heart in acute hypobaric hypoxia exposure and examine the mechanisms by which this occurs...
January 7, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28061144/long-term-health-outcomes-in-high-altitude-pulmonary-hypertension
#13
Jeffrey C Robinson, Cheryl Abbott, Christina A Meadows, Robert C Roach, Benjamin Honigman, Todd M Bull
: Robinson, Jeffrey C., Cheryl Abbott, Christina A. Meadows, Robert C. Roach, Benjamin Honigman, and Todd M. Bull. Long-term health outcomes in high-altitude pulmonary hypertension. High Alt Med Biol. 16:000-000, 2016.-Background: High-altitude pulmonary hypertension (HAPH) is one of several known comorbidities that effect populations living at high altitude, but there have been no studies looking at long-term health consequences of HAPH. We aimed to determine whether HAPH during adolescence predisposes to significant pulmonary hypertension (PH) later in life, as well as identify how altitude exposure and HAPH correlate with functional class and medical comorbidities...
January 6, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28060323/a-model-to-simulate-clinically-relevant-hypoxia-in-humans
#14
Lars Eichhorn, Florian Kessler, Volker Böhnert, Felix Erdfelder, Anja Reckendorf, Rainer Meyer, Richard K Ellerkmann
In case of apnea, arterial partial pressure of oxygen (pO2) decreases, while partial pressure of carbon dioxide (pCO2) increases. To avoid damage to hypoxia sensitive organs such as the brain, compensatory circulatory mechanisms help to maintain an adequate oxygen supply. This is mainly achieved by increased cerebral blood flow. Intermittent hypoxia is a commonly seen phenomenon in patients with obstructive sleep apnea. Acute airway obstruction can also result in hypoxia and hypercapnia. Until now, no adequate model has been established to simulate these dynamics in humans...
December 22, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28057815/susceptibility-to-high-altitude-pulmonary-edema-is-associated-with-a-more-uniform-distribution-of-regional-specific-ventilation
#15
Michael D Patz, Rui Carlos Sá, Chantal Darquenne, Ann R Elliott, Amran K Assadi, Rebecca J Theilmann, David J Dubowitz, Erik Richard Swenson, Gordon Kim Prisk, Susan Roberta Hopkins
High altitude pulmonary edema (HAPE) is a potentially fatal condition affecting high altitude sojourners. The biggest predictor of HAPE development is a history of prior HAPE. Magnetic resonance imaging (MRI) shows HAPE-susceptible, with a history of HAPE, but not HAPE-resistant (a history of repeated ascents without illness) individuals develop greater heterogeneity of regional pulmonary perfusion breathing hypoxic gas (O2=12.5%), consistent with uneven hypoxic pulmonary vasoconstriction (HPV). Why HPV is uneven in HAPE-susceptibles is unknown, but may arise from regionally heterogeneous ventilation resulting in an uneven stimulus to HPV...
January 5, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28055123/regional-variation-in-the-temperature-sensitivity-of-soil-organic-matter-decomposition-in-china-s-forests-and-grasslands
#16
Yuan Liu, Nianpeng He, Jianxing Zhu, Li Xu, Guirui Yu, Shuli Niu, Xiaomin Sun, Xuefa Wen
How to assess the temperature sensitivity (Q10 ) of soil organic matter (SOM) decomposition and its regional variation with high accuracy is one of the largest uncertainties in determining the intensity and direction of the global carbon (C) cycle in response to climate change. In this study, we collected a series of soils from 22 forest sites and 30 grassland sites across China to explore regional variation in Q10 and its underlying mechanisms. We conducted a novel incubation experiment with periodically changing temperature (5-30 °C), while continuously measuring soil microbial respiration rates...
January 5, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28051988/ultraportable-oxygen-concentrator-use-in-u-s-army-special-operations-forward-area-surgery-a-proof-of-concept-in-multiple-environments
#17
Michael Rybak, Lynn C Huffman, Richard Nahouraii, John Loden, Marcos Gonzalez, Ramey Wilson, Paul D Danielson
INTRODUCTION: A limitation to surgical care in an austere environment is the supply of oxygen to support mechanical ventilation and general anesthesia. Portable oxygen concentrators (OCs) offer an alternative to traditional compressed oxygen tanks. OBJECTIVES: We set out to demonstrate that a low-pressure OC system could supply the mechanical ventilation needs in an austere operating environment. METHODS: An ultraportable OC (SAROS Model 3000, SeQual Technologies, Ball Ground, Georgia) was paired with an Impact 754 ventilator (Impact Instrumentation, West Caldwell, New Jersey) to evaluate the delivered fraction of inspired oxygen (FiO2) to a test lung across a range of minute ventilations and at altitudes of 1,200 and 6,500 feet above sea level...
January 2017: Military Medicine
https://www.readbyqxmd.com/read/28050104/high-altitude-induced-laryngopharyngitis-sicca
#18
Ravi Roy
No abstract text is available yet for this article.
December 2016: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28050097/massive-pulmonary-thromboembolism-in-high-altitude-area-versus-high-altitude-pulmonary-oedema
#19
Prabhat Peeyush, Amit Kumar Paliwal, Vivek Sharma
No abstract text is available yet for this article.
December 2016: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28048949/on-the-significance-of-altered-drug-pharmacokinetics-pharmacodynamics-at-high-altitude
#20
Damian M Bailey
No abstract text is available yet for this article.
January 3, 2017: High Altitude Medicine & Biology
keyword
keyword
3777
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"