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Silvia Serino, Giuseppe Riva
In addition to impairments in episodic and spatial memory, anosognosia (i.e., loss of awareness of the deficient aspect of own cognitive functioning) may be considered an important cognitive marker of Alzheimer's disease (AD). However, although a growing body of interesting models have been proposed to explain this early symptom, what is still missing is a unifying framework of all the characteristic signs occurring in patients with AD that may guide the search for its causal neuropathological process and, ultimately, the etiological process...
October 20, 2016: Journal of Alzheimer's Disease: JAD
Robyn M Amos-Kroohs, Laurie L Davenport, Nina Atanasova, Zuhair I Abdulla, Matthew R Skelton, Charles V Vorhees, Michael T Williams
Manganese (Mn) is an essential element but neurotoxic at higher exposure levels. The effects of Mn overexposure (MnOE) on hippocampal and striatal-dependent learning and memory in rats were tested in combination with iron deficiency (FeD) and developmental stress that often co-occur with MnOE. Moderate FeD affects up to 15% of U.S. children and developmental stress is common in lower socio-economic areas where MnOE occurs. Pregnant Sprague-Dawley rats and their litters were housed in cages with or without (barren cage (BAR)) standard bedding from embryonic day (E)7 to postnatal day (P)28...
October 15, 2016: Neurotoxicology and Teratology
Daniel Joel Shaw, Kristína Czekóová, Michaela Porubanová
Accurate distinction between self and other representations is fundamental to a range of social cognitive capacities, and understanding individual differences in this ability is an important aim for psychological research. This demands accurate measures of self-other distinction (SOD). The present study examined an experimental paradigm employed frequently to measure SOD in the action domain; specifically, we evaluated the rotated finger-action stimuli used increasingly to measure automatic imitation (AI). To assess the suitability of these stimuli, we compared AI elicited by different action stimuli to the performance on a perspective-taking task believed to measure SOD in the perception domain...
October 17, 2016: Psychological Research
Yiyun Shou, Martin Sellbom, Jing Xu, Tunong Chen, Aiping Sui
The contemporary knowledge of the construct and operationalization of psychopathy in East Asian countries is still limited. The present paper examines the validity and applicability of the Triarchic Psychopathy Measure (TriPM) based on the triarchic model of psychopathy in Chinese clinical and nonclinical samples. The results of Study 1 using a psychiatric patient sample (N = 193) showed that the pattern of associations between the TriPM scales (Boldness, Meanness, and Disinhibition) and the 3 factors (Egocentricity, Callous, and Antisocial) of the Levenson Self-Report Psychopathy Scale were similar to previous studies using English-speaking samples...
October 13, 2016: Psychological Assessment
B Lembcke
Despite sophisticated physical examination and laboratory support, diagnosis of acute appendicitis remained challenging in clinical practice with a negative appendectomy rate of 15 - 30 %. As a remarkable clue and as early as 1986, ultrasonography (US) has been proven a reliable diagnostic method that is also explicitly helpful in difficult cases with atypical presentation and enables to rule out many differential diagnoses.Recent publications emphasized the role of multidetector computed tomography (CT) resulting in a significant reduction of false negative findings at operation...
October 2016: Zeitschrift Für Gastroenterologie
Ankush Kawali, Ringhoo Theresa Jose, Aishwarya, Mathew Kurian, Kushal Kacha, Padmamalini Mahendradas, Rohit Shetty
BACKGROUND: Psycho-immunology is an emerging branch of science which studies the interaction between the brain and the immune system. The purpose of this study is to identify the types of personality factors in patients with non-infectious uveitis and to find its association with a particular uveitic entity if any. This is a prospective, observational, case-control study of 186 patients with non-infectious uveitis (group A) and controls from general ophthalmology outpatient department (group B)...
December 2016: Journal of Ophthalmic Inflammation and Infection
Janet Klara Djomba, Lijana Zaletel-Kragelj
INTRODUCTION: Research on social networks in public health focuses on how social structures and relationships influence health and health-related behaviour. While the sociocentric approach is used to study complete social networks, the egocentric approach is gaining popularity because of its focus on individuals, groups and communities. METHODS: One of the participants of the healthy lifestyle health education workshop 'I'm moving', included in the study of social support for exercise was randomly selected...
December 1, 2016: Zdravstveno Varstvo
Jacqueline Degen, Andreas Kirbach, Lutz Reiter, Konstantin Lehmann, Philipp Norton, Mona Storms, Miriam Koblofsky, Sarah Winter, Petya B Georgieva, Hai Nguyen, Hayfe Chamkhi, Hanno Meyer, Pawan K Singh, Gisela Manz, Uwe Greggers, Randolf Menzel
Exploration is an elementary and fundamental form of learning about the structure of the world [1-3]. Little is known about what exactly is learned when an animal seeks to become familiar with the environment. Navigating animals explore the environment for safe return to an important place (e.g., a nest site) and to travel between places [4]. Flying central-place foragers like honeybees (Apis mellifera) extend their exploration into distances from which the features of the nest cannot be directly perceived [5-10]...
September 24, 2016: Current Biology: CB
Karin M Vander Heyden, Mariette Huizinga, Maartje E J Raijmakers, Jelle Jolles
The current study investigated development and strategy use of spatial perspective taking (i.e., the ability to represent how an object or array of objects looks from other viewpoints) in children between 8 and 12years of age. We examined this ability with a task requiring children to navigate a route through a model city of wooden blocks from a 90° and 180° rotated perspective. We tested two hypotheses. First, we hypothesized that children's perspective-taking skills increase during this age period and that this process is related to a co-occurring increase in working memory capacity...
September 27, 2016: Journal of Experimental Child Psychology
Gabriele Masi, Annarita Milone, Paola Brovedani, Simone Pisano, Pietro Muratori
Disruptive Behavior Disorders (DBDs) are stable and impairing disorders, heterogeneous in presentation, developmental pathways, and treatment needs. Disentangling subtypes according to psychopathological dimensions is helpful for timely diagnoses, precise prognoses and tailored interventions. Psychopathic traits are relevant in subtyping DBDs with severe antisocial and aggressive behaviors. Three psychopathy dimensions have been found: 1) an affective dimension, the callous-unemotional (CU) trait, with lack of empathy and remorse, and with short-lived emotions; 2) an interpersonal dimension, the narcissistic domain, with manipulative abilities, superficial charm, egocentricity and grandiosity; 3) a behavioral dimension, the impulsivity or impulsive-irresponsibility, with irresponsibility, proneness to boredom, and novelty seeking...
September 25, 2016: Neuroscience and Biobehavioral Reviews
Annelise Raillon Moulinet, Lucie Chochina, Stéphanie Challois Leplaideur, Elise Bannier, Jean-Christophe Ferre, Isabelle Bonan
OBJECTIVE: Subjects use different referentials for spatial localization, and the egocentric references are very often impaired especially during stroke. The objective is to find the difference between activations induced by 2 egocentric tasks MATERIAL/PATIENTS AND METHODS: Seventeen right-handed healthy subjects (50.4±14.9 years) were tested using fMRI during the realization of 2 egocentric spatial tasks: the perception of the straight ahead (retinocentric) and the longitudinal axis of the body (centered by the trunk)...
September 2016: Annals of Physical and Rehabilitation Medicine
Laure Christophe, Eric Chabanat, Ludovic Delporte, Patrice Revol, Sophie Jacquin-Courtois, Pierre Volckmann, Yves Rossetti
OBJECTIVE: Complex regional pain syndrome (CRPS) is an invalidating chronic condition subsequent to peripheral lesions, with frequent therapeutic failure. There is growing consensus for a central contribution to CRPS. However, the nature of this central body representation disorder is increasingly debated. Although it has been repeatedly argued that CRPS results in motor neglect of the affected side, visual egocentric reference frame was found to be deviated towards the pain, i.e. neglect of the healthy side...
September 2016: Annals of Physical and Rehabilitation Medicine
Laure Christophe, Eric Chabanat, Ludovic Delporte, Patrice Revol, Pierre Volckmann, Sophie Jacquin-Courtois, Yves Rossetti
Complex Regional Pain Syndrome (CRPS) is an invalidating chronic condition subsequent to peripheral lesions. There is growing consensus for a central contribution to CRPS. However, the nature of this central body representation disorder is increasingly debated. Although it has been repeatedly argued that CRPS results in motor neglect of the affected side, visual egocentric reference frame was found to be deviated toward the pain, that is, neglect of the healthy side. Accordingly, prism adaptation has been successfully used to normalize this deviation...
2016: Neural Plasticity
Otmar Bock, Nils Bury
INTRODUCTION: To flip a switch "down," our motor system can normally rely on concordant visual, gravitational, and egocentric cues about the vertical. However, divers must sometimes perform this task while visual cues are limited and gravitational cues are misaligned with egocentric cues. Astronauts must also flip switches "down" in absence of gravitational cues. Our study evaluates this ability using a laboratory simulation. METHODS: The subjects were 24 healthy volunteers who were blindfolded, tilted into different angles of roll, and asked to silence an alarm by flipping a switch "down...
2016: Aerospace Medicine and Human Performance
Lin Haijiang, Shen Weiwei, Qiu Danhong, Zhou Sujuan, W U Qionghai, Ding Yingying, Liu Xing, H E Na
Obstract: To characterize and analyze risky sexual networks and genetic scales to potential HIV transmission for HIV seroconcordant couples in Taizhou municipality of Zhejiang Province. Methods: HIV seroconcordant positive couples were invited as index cases to participate in an egocentric survey on HIV related risky behavior and behavioral network prior to HIV diagnosis during 2008-2011. Within-couple HIV transmission pairs were determined by the combination of both behavioral and phylogenetic analysis. Results: Totally 27 HIV seroconcordant couples were enrolled in this study...
May 25, 2016: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
Michiel van Elk, Monique Duizer, Ilja Sligte, Hein van Schie
Given the current debates about the precise functional role of the right temporoparietal junction (rTPJ) in egocentric and exocentric perspective taking, in the present study we manipulated activity in the rTPJ to investigate the effects on a spatial perspective-taking task. Participants engaged in a mental body transformation task, requiring them to mentally rotate their own body to the position of an avatar, while undergoing anodal, cathodal, or sham transcranial direct current stimulation (tDCS) of the rTPJ...
September 20, 2016: Cognitive, Affective & Behavioral Neuroscience
Anna L Hotton, Basmattee Boodram
Persons who inject drugs (PWID) may be at risk of acquiring HIV and sexually transmitted infections (STIs) from risky sexual practices and elevated disease prevalence within their drug injection and sexual networks. We conducted a personal (egocentric) network study of young PWID (aged 18-30) from the Chicago metropolitan area. Logistic regression with generalized estimating equations evaluated associations between individual and network factors and sexual behaviors. Of 162 participants, 116 (71.6 %) were non-Hispanic White and 135 reported on 314 sexual network members...
September 16, 2016: AIDS and Behavior
Emily Cole, Ralph E Mistlberger, Devon Merza, Lianne J Trigiani, Dan Madularu, Amanda Simundic, Dave G Mumby
Circadian time-place learning (TPL) is the ability to remember both the place and biological time of day that a significant event occurred (e.g., food availability). This ability requires that a circadian clock provide phase information (a time tag) to cognitive systems involved in linking representations of an event with spatial reference memory. To date, it is unclear which neuronal substrates are critical in this process, but one candidate structure is the hippocampus (HPC). The HPC is essential for normal performance on tasks that require allocentric spatial memory and exhibits circadian rhythms of gene expression that are sensitive to meal timing...
September 10, 2016: Neurobiology of Learning and Memory
Nina Lisofsky, Jan Wiener, Olivier de Condappa, Jürgen Gallinat, Ulman Lindenberger, Simone Kühn
Pregnancy is accompanied by prolonged exposure to high estrogen levels. Animal studies have shown that estrogen influences navigation strategies and, hence, affects navigation performance. High estrogen levels are related to increased use of hippocampal-based allocentric strategies and decreased use of striatal-based egocentric strategies. In humans, associations between hormonal shifts and navigation strategies are less well studied. This study compared 30 peripartal women (mean age 28years) to an age-matched control group on allocentric versus egocentric navigation performance (measured in the last month of pregnancy) and gray matter volume (measured within two months after delivery)...
October 2016: Neurobiology of Learning and Memory
Daniel Voyer, Petra Jansen, Sandra Kaltner
Two experiments were conducted to address methodological issues with past studies investigating the influence of egocentric and object-based transformations on performance and sex differences in mental rotation. In previous work, the egocentric and object-based mental rotation tasks confounded the stimulus type (embodied vs. non embodied) and transformation task (egocentric vs. object-based). In both experiments presented here, the same stimuli were used regardless of the type of transformation but task instructions were modified to induce either egocentric (left-right judgment) or object-based (same-different judgment) processing...
September 7, 2016: Quarterly Journal of Experimental Psychology: QJEP
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