Nino Eberhardt, Belen Gonzalez Santamarina, Marie-Luise Enghardt, Oliver Rohland, Iqra Hussain, Astrid Tannert, Lara Thieme, Ignacio Rubio, Jürgen Rödel, Bettina Löffler, Hans-Dieter Arndt, Michael Bauer, Anne Busch
This study examines the potential of a novel photoactivatable ciprofloxacin to act against bacterial infections and microbiomes related to biliary diseases. Additionally, the treatment is evaluated combining the impact of bile acids and antibiotics on biofilms Here innovative strategies are evaluated to addressing the elusive bile duct microbiome resulting in biofilm-related infections linked to biliary catheters. The healthy biliary system is considered sterile, but in disease, bile microbiomes can occur, and these correlate with hepatobiliary diseases...
January 11, 2024: International Journal of Antimicrobial Agents