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Perioral dermatitis

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https://www.readbyqxmd.com/read/28747952/human-permanent-ectoparasites-recent-advances-on-biology-and-clinical-significance-of-demodex-mites-narrative-review-article
#1
REVIEW
Dorota Litwin, WenChieh Chen, Ewa Dzika, Joanna Korycińska
BACKGROUND: Demodex is a genus of mites living predominantly in mammalian pilosebaceous units. They are commonly detected in the skin of face, with increasing numbers in inflammatory lesions. Causation between Demodex mites and inflammatory diseases, such as rosacea, blepharitis, perioral and seborrhoeic dermatitis or chalazion, is controversially discussed. Clinical observations indicate a primary form of human Demodex infection. The aim of this review was to highlight the biological aspects of Demodex infestation and point out directions for the future research...
January 2017: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28695412/-basis-for-the-treatment-of-eczematous-diseases-in-otorhinolaryngology
#2
REVIEW
R Fölster-Holst, A Sperl, T Albrecht, L Klimek
According to Coombs and Gell, cell-mediated immune responses belong to type IV reactions and are borne mainly by T lymphocytes. The eliciting allergens are usually so-called haptens. Haptens are substances which develop to whole antigens only by binding to protein carriers. In otorhinolaryngology, delayed allergic hypersensitivities are apparent mainly as contact eczemata. Facial dermatitis, auricle and ear canal eczema as well as perioral eczema belong to the most common forms of contact dermatitis in ENT patients...
July 10, 2017: HNO
https://www.readbyqxmd.com/read/28539982/misuse-of-topical-corticosteroids-on-facial-skin-a-study-of-200-patients
#3
Rohini Sharma, Sameer Abrol, Mashqoor Wani
BACKGROUND: Topical corticosteroids have become available as over the counter drugs and are widely misused for various conditions. OBJECTIVE: The aim of this study is to assess the clinical and epidemiological aspects of the unjustified use of topical corticosteroids for facial skin. METHODS: A total of 200 patients with facial dermatoses and topical corticosteroid misapplication daily over face for not less than 30 days were included in the study...
March 31, 2017: Journal of Dermatological Case Reports
https://www.readbyqxmd.com/read/28524256/quantification-of-l-carvone-in-toothpastes-available-on-the-swedish-market
#4
Liv Kroona, Gunnar Warfvinge, Marléne Isaksson, Camilla Ahlgren, Jakob Dahlin, Östen Sörensen, Magnus Bruze
BACKGROUND: Toothpastes have widespread use in the population, and contain flavours used to give a pleasant and often minty aroma. Flavours are prevalent allergens in toothpastes, and adverse reactions often present as perioral dermatitis or stomatitis. l-Carvone, a mint flavour found in spearmint oil, is one of these allergens. There are few studies on contact allergy to l-carvone, and some of them have indicated a positive relationship with oral lichenoid lesions. OBJECTIVES: To qualitatively and quantitatively investigate the presence of l-carvone in commercially available toothpastes on the Swedish market...
May 19, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28410769/-granulomatous-periocular-eruption
#5
M Moncourier, P Pralong, N Pinel, I Templier, M-T Leccia
BACKGROUND: Herein, we report a case of atypical periorificial dermatitis in a patient that had been receiving treatment for some time for atopic dermatitis. The specific feature of this rash was its periocular predominance with no perioral involvement, its clinical aspect and its histological picture evocative of sarcoidosis. PATIENTS AND METHODS: A 33-year-old man was being treated for a atopic dermatitis limited to the face and poorly responsive to dermal corticosteroids...
April 11, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28243492/usefulness-of-dermoscopy-in-the-diagnosis-and-monitoring-treatment-of-demodicidosis
#6
Paula Friedman, Emilia Cohen Sabban, Horacio Cabo
Demodicidosis is a common infestation and should be considered in the differential diagnosis of recurrent or recalcitrant perioral dermatitis or rosacea-like eruptions of the face. We report on a 34-year-old male, who presented with facial erythema and desquamation accompanied by a pruritic sensation. Dermoscopic examination revealed Demodex tails and Demodex follicular openings, both specific features of this entity. Microscopically, standardized skin surface biopsy test was pathogenic and the patient had positive response to anti-demodectic drugs...
January 2017: Dermatology Practical & Conceptual
https://www.readbyqxmd.com/read/28094753/quantifying-cutaneous-adverse-effects-of-systemic-glucocorticoids-in-patients-with-rheumatoid-arthritis-a-cross-sectional-cohort-study
#7
Jonna Amann, Anne-Marie Wessels, Friederike Breitenfeldt, Dörte Huscher, Johannes W J Bijlsma, Johannes W G Jacobs, Frank Buttgereit
OBJECTIVES: EULAR guidelines state that adverse effects (AEs) of glucocorticoid (GC) therapy should be considered and discussed with the patient before treatment is initiated. However, reliable quantitative data, especially on cutaneous AEs of low-to-medium dose GCs are lacking. We performed a study assessing the occurrence of cutaneous AEs of GCs and its association with current and cumulative GC doses in patients with rheumatoid arthritis (RA). METHODS: In a cross-sectional study performed in 2 outpatient rheumatology centres, 381 RA patients were enrolled...
May 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27910751/recent-advances-in-pharmacotherapeutic-paradigm-of-mild-to-recalcitrant-atopic-dermatitis
#8
REVIEW
Zahid Hussain, Shariza Sahudin, Hnin Ei Thu, Ahmad Nazrun Shuid, Syed Nasir Abbas Bukhari, Endang Kumolosasi
Atopic dermatitis (AD) is a common, chronic skin inflammatory disorder characterized by perivascular infiltration of immunoglobulin E (IgE), T lymphocytes, and mast cells. The key factors responsible for the pathophysiology of this disease are immunological disorders and defects in epidermal barrier properties. Pruritus, intense itching, psychological stress, deprived physical and mental performance, and sleep disturbance are the hallmark features of this dermatological disorder. Preventive interventions such as educational programs, avoidance of allergens, and exclusive care toward the skin could play a partial role in suppressing the symptoms...
2016: Critical Reviews in Therapeutic Drug Carrier Systems
https://www.readbyqxmd.com/read/27265071/inflammatory-and-glandular-skin-disease-in-pregnancy
#9
REVIEW
Catherine S Yang, Mary Teeple, Jennie Muglia, Leslie Robinson-Bostom
A switch from cell-mediated to humoral immunity (helper T 1 [Th1] to helper T 2 [Th2] shift) during gestation plays a key role in placental immune tolerance. As a result, skin diseases that are Th2 mediated often worsen, whereas skin diseases that are Th1 mediated often improve during gestation. Also, due to fluctuations in glandular activity, skin diseases involving sebaceous and eccrine glands may flare, whereas those involving apocrine glands may improve during pregnancy. Despite these trends, inflammatory and glandular skin diseases do not always follow the predicted pattern, and courses are often diverse...
May 2016: Clinics in Dermatology
https://www.readbyqxmd.com/read/26652026/randomized-controlled-double-blind-clinical-study-evaluating-the-safety-and-efficacy-of-md2011001-cream-in-mild-to-moderate-atopic-dermatitis-of-the-face-and-neck-in-children-adolescents-and-adults
#10
RANDOMIZED CONTROLLED TRIAL
Annalisa Patrizi, Beatrice Raone, Iria Neri, Carlotta Gurioli, Monica Carbonara, Nicoletta Cassano, Gino Antonio Vena
INTRODUCTION: This mono-center randomized, controlled, double-blind study evaluates the safety and efficacy of MD2011001 cream versus placebo, in mild-to-moderate atopic dermatitis (AD). MD2011001 is a nonsteroidal topical cream containing vitamin E, epigallocatechin gallate and grape seed procyanidins. METHODS: Patients with AD (corresponding to an IGA score of 2 or 3), involving the face, the perioral/periocular area and/or the neck, were enrolled. Patients were randomized 1:1 ratio to receive MD2011001 or placebo before the start of the study (D0), then evaluated after 7 days, and after 28 days...
August 2016: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/26312592/morphology-based-diagnosis-of-acneiform-eruptions
#11
Sarah L McFarland, Ingrid C Polcari
Acne is the most common skin disease. Distinguishing between true acne vulgaris and the various acneiform eruptions is important yet sometimes challenging. Given the common nature of acne and acneiform eruptions, the pediatrician must be aware of these lesion patterns and possess the skills to effectively evaluate the pediatric presentation of these eruptions. This article discusses several of the most common acneiform eruptions, including neonatal acne and cephalic pustulosis, periorificial dermatitis (perioral dermatitis), facial angiofibromas, iatrogenic acneiform drug eruptions, and childhood rosacea...
August 2015: Pediatric Annals
https://www.readbyqxmd.com/read/26294162/-linear-immunoglobulin-a-bullous-dermatosis-two-cases-report
#12
Leticia González-Martín, Antonio González, María E Pérez-Martín
Linear immunoglobulin A bullous dermatosis is a rare entity with frequent spontaneous resolution. It usually presents in children with average age of 4.5 years. Its incidence is about 0.5-2.3 cases/million individuals/year. It is, after dermatitis herpetiformis, the most frequent paediatric blister disorder. It usually appears in bouts with acute development of vesicles in strings of pearls; affecting the perioral area and genitalia. Diagnosis is based on the clinical signs and symptoms and biopsy of the skin with subepidermal blister and a linear band of immunoglobulin A in the direct immunofluorescence...
October 2015: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/26234523/allergic-perioral-contact-dermatitis-caused-by-rubber-chemicals-during-dental-treatment
#13
Jakob F Schwensen, Torkil Menné, Marianne Hald, Jeanne D Johansen, Jacob P Thyssen
No abstract text is available yet for this article.
February 2016: Contact Dermatitis
https://www.readbyqxmd.com/read/26117625/stk4-mst1-deficiency-in-two-siblings-with-autoimmune-cytopenias-a-novel-mutation
#14
Sevil Oskay Halacli, Deniz Cagdas Ayvaz, Cagman Sun-Tan, Baran Erman, Elif Uz, Didem Yucel Yilmaz, Koksal Ozgul, İlhan Tezcan, Ozden Sanal
Combined immunodeficiencies (CIDs) are heterogeneous group of disorders characterized by abrogated/impaired T cell development and/or functions that resulted from diverse genetic defects. In addition to the susceptibility to infections with various microorganisms, the patients may have lymphoproliferation, autoimmunity, inflammation, allergy and malignancy. Recently, three groups have independently reported patients having mutations in STK4 gene that cause a novel autosomal recessive (AR) CID. We describe here two siblings with a novel STK4 mutation identified during the evaluation of a group of patients with features highly overlapping with those of DOCK-8 deficiency, a form of AR hyperimmunoglobulin E syndrome...
December 2015: Clinical Immunology: the Official Journal of the Clinical Immunology Society
https://www.readbyqxmd.com/read/26096899/mucocutaneous-lupus-erythematosus-in-dogs-21-cases
#15
Thierry Olivry, Michael A Rossi, Frane Banovic, Keith E Linder
BACKGROUND: The diagnosis of dogs with chronic juxtamucosal erosive lesions and histopathology typical of cutaneous lupus erythematosus (CLE) is unclear. HYPOTHESIS/OBJECTIVES: We report herein 21 dogs with mucocutaneous erosive lesions and lupus-specific histopathology that we propose to be affected with mucocutaneous lupus erythematosus (MCLE), another variant of chronic CLE. METHODS: Inclusion criteria were the presence of the following: (i) a >2 month history of chronic or recurrent skin lesions; (ii) erosions or ulcers predominating at mucosae or mucocutaneous junctions; (iii) microscopic lesions of CLE (i...
August 2015: Veterinary Dermatology
https://www.readbyqxmd.com/read/26087223/-bottle-lips-a-new-type-of-perioral-dermatitis
#16
Anca Chiriac, Cosmin Moldovan, Calin Molnar, Cristian Podoleanu, Simona Stolnicu
No abstract text is available yet for this article.
October 2015: Contact Dermatitis
https://www.readbyqxmd.com/read/25744530/-primary-human-demodicosis-a-disease-sui-generis
#17
REVIEW
C-K Hsu, A Zink, K-J Wei, E Dzika, G Plewig, W Chen
Human Demodex mites (Demodex folliculorum and Demodex brevis) are unique in that they are an obligate human ectoparasite that can inhabit the pilosebaceous unit lifelong without causing obvious host immune response in most cases. The mode of symbiosis between humans and human Demodex mites is unclear, while the pathogenicity of human Demodex mites in many inflammatory skin diseases is now better understood. Primary human demodicosis is a skin disease sui generis not associated with local or systemic immunosuppression...
March 2015: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/25714771/-a-girl-with-a-perioral-rash
#18
Lara D de Vries, Wim Opstelten
A 5-year-old girl consulted the general practitioner with perioral skin lesions. Dermatological findings were erythema and squamae with a sharp border, without vesicles or crusts. She had a habit of licking her lips frequently, which is causal for lip licking dermatitis. After stopping this habit, the skin healed, without application of dermal therapy.
2015: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/25649466/complications-of-injected-vitamin-e-as-a-filler-for-lip-augmentation-case-series-and-therapeutic-approach
#19
Ban Kamouna, Razvigor Darlenski, Jana Kazandjieva, Maria Balabanova, Lubomir Dourmishev, Zorka Negentsova, Doncho Etugov, Biljana Mirchevska, Nikolai Tsankov
The strive for proficient cosmetic facial appearance is growing in the past decades. Fillers for tissue augmentation are gaining wide popularity. Uncertified products based on oleic solutions are applied by untrained staff, thus growing the risk for certain complications such as infections, allergic and irritant contact dermatitis, and lipogranuloma formation. We present a series of three cases lipogranuloma after liquid vitamin E injection for lip augmentation. In all cases, painful edema at the injected area followed the procedure...
March 2015: Dermatologic Therapy
https://www.readbyqxmd.com/read/25335357/phytodermatitis-to-euphorbia-trigona
#20
Razvigor Darlenski, Jana Kazandjieva, Nikolai Tsankov
A 56-year-old Caucasian woman presented with acute onset of dermatitis on her face accompanied by intense itching. The patient reported that the condition began after cleaning a decorative plant, Euphorbia trigona, and contact with some drops of the plant's latex sap released upon cutting its leaves. The clinical examination revealed erythema and edema of the infraorbital and perioral regions (Figure 1). The patient was in otherwise good general health, had no personal or family history of systemic or skin disease, and was not receiving any concomitant medications...
July 2014: Skinmed
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