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https://www.readbyqxmd.com/read/28334035/early-inner-retinal-thinning-and-cardiovascular-autonomic-dysfunction-in-type-2-diabetes
#1
Jin A Choi, Hyo Won Kim, Jin-Woo Kwon, Yun-Sub Shim, Dong Hyun Jee, Jae-Seung Yun, Yu-Bae Ahn, Chan Kee Park, Seung-Hyun Ko
BACKGROUND: To investigate changes in the neural retina according to the presence of retinal nerve fiber layer (RNFL) defects in type 2 diabetes, and to determine the association between inner retina thickness and the severity of diabetic complications. METHODS: We studied non-glaucomatous patients with type 2 diabetes and control subjects Circumpapillary RNFL and macula ganglion cell-inner plexiform layer (GCIPL) thicknesses were measured by spectral-domain optical coherence tomography...
2017: PloS One
https://www.readbyqxmd.com/read/28333011/utility-of-deep-inspiration-breath-hold-for-left-sided-breast-radiation-therapy-in-preventing-early-cardiac-perfusion-defects-a-prospective-study
#2
Timothy M Zagar, Orit Kaidar-Person, Xiaoli Tang, Ellen E Jones, Jason Matney, Shiva K Das, Rebecca L Green, Arif Sheikh, Amir H Khandani, William H McCartney, Jorge Daniel Oldan, Terence Z Wong, Lawrence B Marks
PURPOSE: To evaluate early cardiac single photon computed tomography (SPECT) findings after left breast/chest wall postoperative radiation therapy (RT) in the setting of deep inspiration breath hold (DIBH). METHODS AND MATERIALS: We performed a prospective single-institution single-arm study of patients who were planned for tangential RT with DIBH to the left breast/chest wall (± internal mammary nodes). The DIBH was done by use of a controlled surface monitoring technique (AlignRT, Vision RT Ltd, London, UK)...
April 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28325598/sudomotor-dysfunction-as-a-measure-of-small-fiber-neuropathy-in-type-1-diabetes
#3
Lynn Ang, Mamta Jaiswal, Brian Callaghan, David Raffel, Morton B Brown, Rodica Pop-Busui
BACKGROUND: This study evaluated whether measuring the electrochemical skin conductance (ESC), as an indirect measure of sudomotor function, may be also a reliable surrogate for early cardiovascular autonomic neuropathy (CAN). METHODS: Longitudinal study included 37 type 1 diabetes (T1D) subjects (mean age 38±13years, duration 15±7years, HbA1c 7.9±1.1%, no known complications at baseline), and 40 age-matched healthy control (HC) subjects. Mean hands ESC (ESChands) and feet (ESCfeet) were measured with the SUDOSCAN (Impeto Medical, France)...
March 10, 2017: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/28324987/sleep-architecture-measurement-based-on-cardiorespiratory-parameters
#4
Alexander Tataraidze, Lyudmila Korostovtseva, Lesya Anishchenko, Mikhail Bochkarev, Yurii Sviryaev
This paper presents a method for the detection of wakeful state, rapid eye movement sleep (REM), light sleep (N1&N2) and deep sleep (N3&N4) based on cardiorespiratory parameters. Experiments were conducted with data of 625 subjects without sleep-disordered breathing selected from the SHHS dataset. Compared to previous studies, our method considers results of neighboring epochs classification and epoch position over record time. The method demonstrates Cohen's kappa of 0.57 ± 0.13 and the accuracy of 71.4 ± 8...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28316590/rehabilitation-using-guided-cerebral-plasticity-of-a-brachial-plexus-injury-treated-with-intercostal-and-phrenic-nerve-transfers
#5
Lars B Dahlin, Gert Andersson, Clas Backman, Hampus Svensson, Anders Björkman
Recovery after surgical reconstruction of a brachial plexus injury using nerve grafting and nerve transfer procedures is a function of peripheral nerve regeneration and cerebral reorganization. A 15-year-old boy, with traumatic avulsion of nerve roots C5-C7 and a non-rupture of C8-T1, was operated 3 weeks after the injury with nerve transfers: (a) terminal part of the accessory nerve to the suprascapular nerve, (b) the second and third intercostal nerves to the axillary nerve, and (c) the fourth to sixth intercostal nerves to the musculocutaneous nerve...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28301417/inhaled-sedation-in-patients-with-acute-respiratory-distress-syndrome-undergoing-extracorporeal-membrane-oxygenation
#6
Andreas Meiser, Hagen Bomberg, Philipp M Lepper, Franziska C Trudzinski, Thomas Volk, Heinrich V Groesdonk
Six patients suffering from acute respiratory distress syndrome with the need for extracorporeal membrane oxygenation (ECMO) therapy in deep sedation were included. Isoflurane sedation with the AnaConDa system was initiated within 24 hours after initiation of ECMO therapy and resulted in a satisfactory sedation (Richmond Agitation-Sedation Scale -4 to -5). Despite deep sedation, spontaneous breathing was possible in 6 of 6 patients. We observed a reduced need for vasopressor therapy and improved lung function (PaO2, PaCO2, delta P, and tidal volume) during isoflurane sedation...
March 15, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28297458/translucent-poly-vinyl-alcohol-cryogel-dosimeters-for-simultaneous-dose-buildup-and-monitoring-during-chest-wall-radiation-therapy
#7
Molham M Eyadeh, Mark A Weston, Janos Juhasz, Kevin R Diamond
Chest wall radiation therapy treatment delivery was monitored using a 5 mm thick radiochromic poly(vinyl alcohol) cryogel that also provided buildup material. The cryogels were used to detect positioning errors and measure the impact of shifts for a chest wall treatment that was delivered to a RANDO phantom. The phantom was shifted by ±2,±3, and ±5 mm from the planned position in the anterior/posterior (A/P) direction; these shifts represent setup errors and the uncertainty associated with lung filling during breath-hold...
September 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28297438/technical-note-a-respiratory-monitoring-and-processing-system-based-on-computer-vision-prototype-and-proof-of-principle
#8
Nicolas Leduc, Vincent Atallah, Patrick Escarmant, Vincent Vinh-Hung
Monitoring and controlling respiratory motion is a challenge for the accuracy and safety of therapeutic irradiation of thoracic tumors. Various commercial systems based on the monitoring of internal or external surrogates have been developed but remain costly. In this article we describe and validate Madibreast, an in-house-made respiratory monitoring and processing device based on optical tracking of external markers. We designed an optical apparatus to ensure real-time submillimetric image resolution at 4 m...
September 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28297275/how-dose-sparing-of-cardiac-structures-correlates-with-in-field-heart-volume-and-sternal-displacement
#9
Taeho Kim, Kelli Reardon, Daniel M Trifiletti, Constance Geesey, Kaitlyn Sukovich, Edwin Crandley, Paul W Read, Krishni Wijesooriya
Cardiac irradiation increases the risk of coronary artery disease in patients with left-sided breast cancer. Techniques exist to reduce cardiac irradiation, but the optimum technique depends on individual patient anatomy and physiology. We investigated the correlation of delta heart volume in field (dHVIF) and sternal excursion with dose sparing in heart and left anterior descending artery (LAD) to develop quantitative predictive models for expected dose to heart and LAD. A treatment planning study was performed on 97 left-breast cancer patients who underwent whole breast radiotherapy (prescription dose = 50 Gy) under deep inspiratory breath hold (DIBH)...
November 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28296326/evaluation-of-target-and-cardiac-position-during-visually-monitored-deep-inspiration-breath-hold-for-breast-radiotherapy
#10
Leigh Conroy, Rosanna Yeung, Elizabeth Watt, Sarah Quirk, Karen Long, Alana Hudson, Tien Phan, Wendy L Smith
A low-resource visually monitored deep inspiration breath-hold (VM-DIBH) technique was successfully implemented in our clinic to reduce cardiac dose in left-sided breast radiotherapy. In this study, we retrospectively characterized the chest wall and heart positioning accuracy of VM-DIBH using cine portal images from 42 patients. Central chest wall position from field edge and in-field maximum heart distance (MHD) were manually measured on cine images and compared to the planned positions based on the digitally reconstructed radiographs (DRRs)...
July 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28291926/development-of-a-deep-inspiration-breath-hold-system-for-radiotherapy-utilizing-a-laser-distance-measurer
#11
Christer Andre Jensen, Nils Skottner, Jomar Frengen, Jo-Åsmund Lund
Deep inspiration breath-hold (DIBH) is a technique for treating left-sided breast cancer (LSBC). In modern radiotherapy, one of the main aims is to exclude the heart from the beam aperture with an individualized beam design for LSBC. A deep inhalation will raise the chest wall while the volume of the lungs increase, this will again push the heart away from the breast to be treated. There are a few commercial DIBH systems, both invasive and noninvasive. We present an alternative noninvasive DIBH system based upon an industrial laser distance measurer...
January 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28286774/orthostatic-intolerance-and-postural-orthostatic-tachycardia-syndrome-in-joint-hypermobility-syndrome-ehlers-danlos-syndrome-hypermobility-type-neurovegetative-dysregulation-or-autonomic-failure
#12
Claudia Celletti, Filippo Camerota, Marco Castori, Federica Censi, Laura Gioffrè, Giovanni Calcagnini, Stefano Strano
Background. Joint hypermobility syndrome/Ehlers-Danlos syndrome, hypermobility type (JHS/EDS-HT), is a hereditary connective tissue disorder mainly characterized by generalized joint hypermobility, skin texture abnormalities, and visceral and vascular dysfunctions, also comprising symptoms of autonomic dysfunction. This study aims to further evaluate cardiovascular autonomic involvement in JHS/EDS-HT by a battery of functional tests. Methods. The response to cardiovascular reflex tests comprising deep breathing, Valsalva maneuver, 30/15 ratio, handgrip test, and head-up tilt test was studied in 35 JHS/EDS-HT adults...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28281859/geometrical-uncertainty-of-heart-position-in-deep-inspiration-breath-hold-radiotherapy-of-left-sided-breast-cancer-patients
#13
Tuomas Koivumäki, Juuso Tujunen, Tuomas Virén, Janne Heikkilä, Jan Seppälä
BACKGROUND: This study aimed to determine the geometrical uncertainty of the position of the heart with daily cone beam computed tomography (CBCT) during deep-inspiration breath-hold (DIBH) treatment of the left breast. MATERIAL AND METHODS: A visually guided optical respiratory monitoring system was used in DIBH treatment of 15 breast cancer patients. Heart position was determined in relation to the planning target volume (PTV) in 225 fractions in which daily low-dose CBCT images were compared with planning CT images...
March 10, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28274398/lower-mean-heart-dose-with-deep-inspiration-breath-hold-whole-breast-irradiation-compared-with-brachytherapy-based-accelerated-partial-breast-irradiation-for-women-with-left-sided-tumors
#14
Emma B Holliday, Steve M Kirsner, Howard D Thames, Bryan E Mason, Christopher L Nelson, Elizabeth S Bloom
PURPOSE: For left-sided breast cancer, radiation to the heart is a concern. We present a comparison of mean heart and coronary artery biologically effective dose (BED) between accelerated partial breast irradiation (APBI) and whole breast irradiation with deep inspiration breath-hold technique (DIBH-WBI). METHODS AND MATERIALS: A total of 100 patients with left-sided, early-stage breast cancer were identified. Fifty underwent single-entry catheter-based APBI and 50 underwent DIBH-WBI...
March 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28268908/bioradiolocation-based-sleep-stage-classification
#15
Alexander Tataraidze, Lyudmila Korostovtseva, Lesya Anishchenko, Mikhail Bochkarev, Yurii Sviryaev, Sergey Ivashov
This paper presents a method for classifying wakefulness, REM, light and deep sleep based on the analysis of respiratory activity and body motions acquired by a bioradar. The method was validated using data of 32 subjects without sleep-disordered breathing, who underwent a polysomnography study in a sleep laboratory. We achieved Cohen's kappa of 0.49 in the wake-REM-light-deep sleep classification, 0.55 for the wake-REM-NREM classification and 0.57 for the sleep/wakefulness determination. The results might be useful for the development of unobtrusive sleep monitoring systems for diagnostics, prevention, and management of sleep disorders...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28261872/tracking-discrete-off-resonance-markers-with-three-spokes-trackdots-for-compensation-of-head-motion-and-b0-perturbations-accuracy-and-performance-in-anatomical-imaging
#16
João Jorge, Frédéric Gretsch, Daniel Gallichan, José P Marques
PURPOSE: To develop a novel approach for head motion and B0 field monitoring based on tracking discrete off-resonance markers with three spokes (trackDOTS). METHODS: Small markers filled with acetic acid were built and attached to a head cap. Marker positions and phase were tracked with fast MR navigators (DotNavs) consisting of three off-resonance, double-echo, orthogonal one-dimensional projections. Individual marker signals were extracted using optimized coil combinations, and used to estimate head motion and field perturbations...
March 5, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28261509/spontaneous-heparin-induced-thrombocytopenia-and-venous-thromboembolism-following-total-knee-arthroplasty
#17
Kevin Baker, Ming Y Lim
A 72-year-old Caucasian woman was admitted for an elective left total knee arthroplasty. Her surgery was uncomplicated and she was discharged to a rehabilitation facility. Twelve days later, she developed acute shortness of breath followed by a syncopal episode. She was hypoxic and cyanotic, requiring hospitalization and intubation, and was subsequently diagnosed with bilateral submassive pulmonary emboli and bilateral lower extremity deep vein thrombosis. She was started on unfractionated heparin infusion...
2017: Case Reports in Hematology
https://www.readbyqxmd.com/read/28254102/auricular-acupuncture-analgesia-in-thoracic-trauma-a-case-report
#18
Georgios S Papadopoulos, Petros Tzimas, Antonia Liarmakopoulou, Anastasios M Petrou
We report a case of thoracic trauma (rib fractures with pneumothorax and pulmonary contusions) with severe chest pain leading to ineffective ventilation and oxygenation. The patient presented to our emergency department. The patient had chronic obstructive pulmonary disease and was completely unable to take deep breaths and clear secretions from his bronchial tree. After obtaining informed consent, we applied auricular acupuncture to ameliorate pain and hopefully improve his functional ability to cough and breathe deeply...
January 2017: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/28245908/target-position-uncertainty-during-visually-guided-deep-inspiration-breath-hold-radiotherapy-in-locally-advanced-lung-cancer
#19
Jonas Scherman Rydhög, Steen Riisgaard de Blanck, Mirjana Josipovic, Rasmus Irming Jølck, Klaus Richter Larsen, Paul Clementsen, Thomas Lars Andersen, Per Rugaard Poulsen, Gitte Fredberg Persson, Per Munck Af Rosenschold
PURPOSE: The purpose of this study was to estimate the uncertainty in voluntary deep-inspiration breath-hold (DIBH) radiotherapy for locally advanced non-small cell lung cancer (NSCLC) patients. METHODS: Perpendicular fluoroscopic movies were acquired in free breathing (FB) and DIBH during a course of visually guided DIBH radiotherapy of nine patients with NSCLC. Patients had liquid markers injected in mediastinal lymph nodes and primary tumours. Excursion, systematic- and random errors, and inter-breath-hold position uncertainty were investigated using an image based tracking algorithm...
February 25, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28237935/biopad-leveraging-off-the-shelf-video-games-for-stress-self-regulation
#20
Zelun Wang, Avinash Parnandi, Ricardo Gutierrez-Osuna
This paper presents an approach to use commercial videogames for biofeedback training. It consists of intercepting signals from the game controller and adapting them in real-time based on physiological measurements from the player. We present three sample implementations and a case study for teaching stress self-regulation via an immersive car racing game. We use a crossover gaming device to manipulate controller signals, and a respiratory sensor to monitor the players' breathing rate. We then alter the speed of the car to encourage slow, deep breathing, in this way allowing players to reduce their arousal while playing the game...
February 20, 2017: IEEE Journal of Biomedical and Health Informatics
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