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Urinary diversion

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https://www.readbyqxmd.com/read/28425193/health-related-quality-of-life-outcomes-from-a-contemporary-prostate-cancer-registry-in-a-large-diverse-population
#1
Gary W Chien, Jeff M Slezak, Teresa N Harrison, Howard Jung, Joy S Gelfond, Chengyi Zhang, Edward Wu, Richard Contreras, Ronald K Loo, Steven J Jacobsen
OBJECTIVE: To assess the health-related quality of life (HRQoL) of patients with prostate cancer up to 24 months after treatment in a contemporary large diverse population. PATIENTS AND METHODS: Patients with newly diagnosed prostate cancer from March 2011 to January 2014 in our healthcare system were included. The Expanded Prostate Cancer Index Composite (EPIC-26) questionnaire was administered before treatment, and at 1, 3, 6, 12, 18, and 24 months after treatment up to November 2014 for all methods of treatment...
April 19, 2017: BJU International
https://www.readbyqxmd.com/read/28422039/-urinary-tract-lymphoepithelial-carcinoma-report-of-two-cases-and-bibliographic-review
#2
Sebastian Valverde Martínez, Waleska Salcedo Mercado, Isabel Rodríguez Cruz, Sara Belén Prieto Nogal, Mario Martín Hernández, Luis Miguel Gómez Tejeda
OBJECTIVE: We report two cases of patients diagnosed with lymphoepithelioma-like carcinomas of the urinary tract. We review the literature of this rare entity. The objective is to clarify the clinical and therapeutic characteristics. METHODS: We present a retrospective review of medical records of two patients diagnosed with lymphoepithelioma-like carcinomas, one in the renal pelvis and the other in the bladder. We review the epidemiology, diagnosis and therapeutic alternatives...
April 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28411100/w-pouch-with-modified-non-isolated-extra-limb-for-continence-in-cutaneous-diversion-after-radical-cystectomy
#3
Khaled M Abd Elwahab, Ahmed M Eliwa, Mohammed M Seleem, Maged M Ali, Islam M El-Babouly, Ahmed Ragab, Mohammed Naguib, Hamdy M Desouky, Esam A E Desoky, Mohammed Omran, Hussein M Kamel
OBJECTIVE: To report the functional results of continent cutaneous ileal urinary diversion using modified W-pouch with non-isolated extra limb for continence . PATIENTS & METHODS: From January 2013 to January 2016, 21 patients with muscle-invasive bladder cancer with with median (interquartile range) of 59 (56.5-62.5) years old underwent radical cystectomy with pelvic lymphadenectomy; they then had an ileal continent cutaneous pouch constructed from W-pouch with non-isolated extra limb for continence...
April 11, 2017: Urology
https://www.readbyqxmd.com/read/28408060/bacterial-epidemiology-and-antimicrobial-resistance-profiles-of-urinary-specimens-of-the-elderly
#4
F Gravey, G Loggia, A de La Blanchardière, V Cattoir
OBJECTIVE: Although urinary tract infections are the second leading cause of infections among patients aged above 65 years, data on bacterial epidemiology of urinary specimens in these patients is scarce. Our aim was to describe the main bacterial species found at significant levels in urine specimens of the elderly and to determine their antimicrobial resistance profiles. METHODS: From October 2012 to October 2015, all urinary specimens (catheter-related or not) received at the laboratory of microbiology of the university hospital of Caen (France) were retrospectively studied...
April 10, 2017: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/28398930/management-of-mesh-and-graft-complications-in-gynecologic-surgery
#5
(no author information available yet)
This document focuses on the management of complications related to mesh used to correct stress urinary incontinence or pelvic organ prolapse. Persistent vaginal bleeding, vaginal discharge, or recurrent urinary tract infections after mesh placement should prompt an examination and possible further evaluation for exposure or erosion. A careful history and physical examination is essential in the diagnosis of mesh and graft complications. A clear understanding of the location and extent of mesh placement, as well as the patient's symptoms and therapy goals, are necessary to plan treatment approaches...
April 10, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28396183/the-impact-of-health-literacy-and-clinicodemographic-factors-on-use-of-discharge-services-after-radical-cystectomy
#6
Stephen F Kappa, Kristen R Scarpato, Kathryn M Goggins, Sunil Kripalani, Kelvin A Moses
PURPOSE: There are few data regarding the relationship between health literacy and discharge disposition. We hypothesized that patient discharge needs after radical cystectomy (RC) are affected by health literacy. MATERIALS AND METHODS: We identified 504 patients who underwent RC and completed the validated Brief Health Literacy Screen (BHLS) since November 2010. Bivariate and logistic regression analyses were performed to determine if health literacy was associated with utilization of discharge resources after RC...
April 7, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28391960/rapid-detection-of-urinary-tract-infections-via-bacterial-nuclease-activity
#7
Katie S Flenker, Elliot L Burghardt, Nirmal Dutta, William J Burns, Julia M Grover, Elizabeth J Kenkel, Tyler M Weaver, James Mills, Hyeon Kim, Lingyan Huang, Richard Owczarzy, Catherine A Musselman, Mark A Behlke, Bradley Ford, James O McNamara
Rapid and accurate bacterial detection methods are needed for clinical diagnostic, water, and food testing applications. The wide diversity of bacterial nucleases provides a rich source of enzymes that could be exploited as signal amplifying biomarkers to enable rapid, selective detection of bacterial species. With the exception of the use of micrococcal nuclease activity to detect Staphylococcus aureus, rapid methods that detect bacterial pathogens via their nuclease activities have not been developed. Here, we identify endonuclease I as a robust biomarker for E...
April 5, 2017: Molecular Therapy: the Journal of the American Society of Gene Therapy
https://www.readbyqxmd.com/read/28373152/the-systematic-classification-of-urinary-stones-combine-using-ftir-and-sem-edax
#8
REVIEW
Rui-Hong Ma, Xiao-Bing Luo, Qin Li, Hai-Qiang Zhong
BACKGROUND: To explore underlying mechanism of urinary stones formation, the composition and microstructure of urinary stones were analyzed systematically with a large sample study from China. MATERIALS AND METHODS: A total of 2437 urinary stones were obtained from the urology department at our Hospital. The composition of the stones was analyzed by Fourier transform infrared spectroscopy (FTIR). Meanwhile, the microstructure and element distribution were observed with scanning electron microscopy combined with element distribution analysis (SEM-EDAX)...
March 31, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28370930/long-term-third-party-assessment-of-results-after-continent-cutaneous-diversion-with-lundiana-pouch
#9
Fredrik Liedberg, Sigurdur Gudjonsson, Abai Xu, Pär-Ola Bendahl, Thomas Davidsson, Wiking Månsson
OBJECTIVES: To investigate functional outcomes and complications at long-term follow-up after continent cutaneous diversion with Lundiana pouch. SUBJECTS AND METHODS: Complications, reoperations, renal function, and continence were ascertained from patient charts. Outcome variables were validated by a second and independent review of the patient files. RESULTS: A complication Clavien grade 3 or higher including unscheduled readmissions occurred in 45/193 patients (23%) within 90 days of surgery...
March 29, 2017: BJU International
https://www.readbyqxmd.com/read/28360953/diabetes-and-elevated-urea-level-predict-for-uretero-ileal-stricture-after-radical-cystectomy-and-ileal-conduit-formation
#10
Nathan Hoag, Nathan Papa, Bhawanie Koonj Beharry, Nathan Lawrentschuk, Danny Chiu, Shomik Sengupta, Damien Bolton
INTRODUCTION: Benign uretero-ileal anastomotic stricture is a significant complication following radical cystectomy and ileal conduit urinary diversion after radical cystectomy. We examined risk factors for stricture formation to predict those at greatest stricture risk. METHODS: A retrospective chart review was conducted for patients undergoing radical cystectomy and ileal conduit diversion between 2002 and 2012. Demographic data and patient variables were analyzed to determine risk factors for uretero-ileal stricture using multivariate logistic regression...
March 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28351650/in-pursuit-of-the-perfect-penis-hypospadias-repair-outcomes
#11
EDITORIAL
Brenton B Winship, H Gil Rushton, Hans G Pohl
Hypospadias is commonly assessed and repaired by pediatric urologists. Mild, distal hypospadias is generally more a cosmetic problem than a functional one and is more frequently encountered than severe, proximal hypospadias. Outcomes following repair, especially of mild phenotypes, are important to understand, but range widely in timing and measurability. Surgical complications, postoperative satisfaction of parents, patients, surgeons and even lay observers, urinary function, sexual function, and quality of life all may be considered as relevant outcomes of hypospadias repair...
March 15, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28348063/long-term-endothelin-a-receptor-antagonism-provides-robust-renal-protection-in-humanized-sickle-cell-disease-mice
#12
Malgorzata Kasztan, Brandon M Fox, Joshua S Speed, Carmen De Miguel, Eman Y Gohar, Tim M Townes, Abdullah Kutlar, Jennifer S Pollock, David M Pollock
Sickle cell disease (SCD)-associated nephropathy is a major source of morbidity and mortality in patients because of the lack of efficacious treatments targeting renal manifestations of the disease. Here, we describe a long-term treatment strategy with the selective endothelin-A receptor (ETA) antagonist, ambrisentan, designed to interfere with the development of nephropathy in a humanized mouse model of SCD. Ambrisentan preserved GFR at the level of nondisease controls and prevented the development of proteinuria, albuminuria, and nephrinuria...
March 27, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/28348010/distinctive-risk-factors-and-phenotype-of-younger-patients-with-resistant-hypertension-age-is-relevant
#13
Lama Ghazi, Suzanne Oparil, David A Calhoun, Chee Paul Lin, Tanja Dudenbostel
Resistant hypertension, defined as blood pressure >140/90 mm Hg despite using ≥3 antihypertensive medications, is a well-recognized clinical entity. Patients with resistant hypertension are at an increased risk of cardiovascular disease compared with those with more easily controlled hypertension. Coronary heart disease mortality rates of younger adults are stagnating or on the rise. The purpose of our study was to characterize the phenotype and risk factors of younger patients with resistant hypertension, given the dearth of data on cardiovascular risk profile in this cohort...
March 27, 2017: Hypertension
https://www.readbyqxmd.com/read/28344124/comparative-genomics-of-transport-proteins-in-probiotic-and-pathogenic-escherichia-coli-and-salmonella-enterica-strains
#14
Jimmy Do, Hassan Zafar, Milton H Saier
Escherichia coli is a genetically diverse species that can be pathogenic, probiotic, commensal, or a harmless laboratory strain. Pathogenic strains of E. coli cause urinary tract infections, diarrhea, hemorrhagic colitis, and pyelonephritis, while the two known probiotic E. coli strains combat inflammatory bowel disease and play a role in immunomodulation. Salmonella enterica, a close relative of E. coli, includes two important pathogenic serovars, Typhi and Typhimurium, causing typhoid fever and enterocolitis in humans, respectively, with the latter strain also causing a lethal typhoid fever-like disease in mice...
March 24, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28339785/a-food-debris-like-component-in-the-urine-sediment-from-a-urostomy-pouch
#15
Michiko Yamashita, Masaki Hotta, Kiyoshi Yoshino, Yoh Hidaka, Tadashi Kimura
Microscopic examination of urine sediment is a basic, common method of detecting diseases of the urinary tract. We experienced a case involving a patient who had developed a fever after undergoing a urinary-diversion operation. Results of the microscopic examination of the urine collected from the urostomy pouch of the patient showed a food debris-like component. Based on this finding, we suspected a fistula between the urinary and intestinal tracts. However, after performing an experiment to verify the results, we determined that no fistula was present...
March 2, 2017: Laboratory Medicine
https://www.readbyqxmd.com/read/28336308/robotic-intracorporeal-continent-cutaneous-diversion
#16
Mihir M Desai, Giuseppe Simone, Andre Luis de Castro Abreu, Sameer Chopra, Mariaconsiglia Ferriero, Salvatore Guaglianone, Francesco Minisola, Daniel Park, Rene Sotelo, Michele Gallucci, Inderbir S Gill, Monish Aron
PURPOSE: Robotic intra-corporeal urinary diversion has mostly been utilized for ileal conduit or orthotopic neobladder diversion. Herein, we present the initial series, detailed technique and outcomes of robotic intra-corporeal Indiana pouch, with minimum 1-year follow-up. MATERIALS AND METHODS: Ten patients underwent robotic radical cystectomy, pelvic lymphadenectomy and intra-corporeal Indiana pouch urinary diversion for cancer (n=9) or benign disease (n=1). Data were collected prospectively...
March 21, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28333822/committee-opinion-no-694-management-of-mesh-and-graft-complications-in-gynecologic-surgery
#17
(no author information available yet)
This document focuses on the management of complications related to mesh used to correct stress urinary incontinence or pelvic organ prolapse. Persistent vaginal bleeding, vaginal discharge, or recurrent urinary tract infections after mesh placement should prompt an examination and possible further evaluation for exposure or erosion. A careful history and physical examination is essential in the diagnosis of mesh and graft complications. A clear understanding of the location and extent of mesh placement, as well as the patient's symptoms and therapy goals, are necessary to plan treatment approaches...
April 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28333814/committee-opinion-no-694-summary-management-of-mesh-and-graft-complications-in-gynecologic-surgery
#18
(no author information available yet)
This document focuses on the management of complications related to mesh used to correct stress urinary incontinence or pelvic organ prolapse. Persistent vaginal bleeding, vaginal discharge, or recurrent urinary tract infections after mesh placement should prompt an examination and possible further evaluation for exposure or erosion. A careful history and physical examination is essential in the diagnosis of mesh and graft complications. A clear understanding of the location and extent of mesh placement, as well as the patient's symptoms and therapy goals, are necessary to plan treatment approaches...
April 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28333758/cutaneous-burn-injury-modulates-urinary-antimicrobial-peptide-responses-and-the-urinary-microbiome
#19
Jennifer K Plichta, Casey J Holmes, Vanessa Nienhouse, Michelle Puszynski, Xiang Gao, Qunfeng Dong, Huaiying Lin, James Sinacore, Michael Zilliox, Evelyn Toh, David E Nelson, Richard L Gamelli, Katherine A Radek
OBJECTIVES: Characterization of urinary bacterial microbiome and antimicrobial peptides after burn injury to identify potential mechanisms leading to urinary tract infections and associated morbidities in burn patients. DESIGN: Retrospective cohort study using human urine from control and burn subjects. SETTING: University research laboratory. PATIENTS: Burn patients. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Urine samples from catheterized burn patients were collected hourly for up to 40 hours...
March 22, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28330863/bacterial-virulence-phenotypes-of-escherichia-coli-and-host-susceptibility-determine-risk-for-urinary-tract-infections
#20
Henry L Schreiber, Matt S Conover, Wen-Chi Chou, Michael E Hibbing, Abigail L Manson, Karen W Dodson, Thomas J Hannan, Pacita L Roberts, Ann E Stapleton, Thomas M Hooton, Jonathan Livny, Ashlee M Earl, Scott J Hultgren
Urinary tract infections (UTIs) are caused by uropathogenic Escherichia coli (UPEC) strains. In contrast to many enteric E. coli pathogroups, no genetic signature has been identified for UPEC strains. We conducted a high-resolution comparative genomic study using E. coli isolates collected from the urine of women suffering from frequent recurrent UTIs. These isolates were genetically diverse and varied in their urovirulence, that is, their ability to infect the bladder in a mouse model of cystitis. We found no set of genes, including previously defined putative urovirulence factors (PUFs), that were predictive of urovirulence...
March 22, 2017: Science Translational Medicine
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