keyword
https://read.qxmd.com/read/37607849/does-previous-endoscopic-subureteric-injection-sting-effect-the-outcomes-of-robot-assisted-laparoscopic-ureteral-reimplantation-surgery-ralur-in-children
#21
JOURNAL ARTICLE
Ilker Comez, Taha Ucar, Onur Telli, Bilal Gunaydin, M Selcuk Silay
BACKGROUND: There is lack of evidence on the success of robot-assisted laparoscopic ureteral reimplantation (RALUR) for the treatment of vesicoureteral reflux (VUR) who had prior intervention. OBJECTIVE: This study aimed to evaluate the effect of previous unsuccessful STING on the outcomes of RALUR in children. STUDY DESIGN: A total of 67 children treated with RALUR by a single surgeon for the treatment of VUR were scanned between February 2018 and April 2022...
August 2, 2023: Journal of Pediatric Urology
https://read.qxmd.com/read/37468395/primary-repair-vs-delayed-staged-repair-in-infants-with-primary-obstructive-megaureters-and-their-long-term-outcomes-a-single-centre-experience
#22
JOURNAL ARTICLE
Neehar Patil, Tarun Javali, Padmalatha S Kadamba
BACKGROUND: There is paucity of literature in the management of infants with primary obstructive megaureters undergoing upfront primary repair with an extravesical technique of ureteral re implantation (with or without ureteral tailoring). OBJECTIVE: To compare 2 different approaches in the management of infants with unilateral primary obstructive megaureters. STUDY DESIGN: This was a retrospective analysis of a prospectively maintained data base between 2005 and 2021...
July 6, 2023: Journal of Pediatric Urology
https://read.qxmd.com/read/37425259/ureteral-dilation-recovery-after-intravesical-reimplantation-in-children-with-primary-obstructive-megaureter
#23
JOURNAL ARTICLE
Yan He, Xuemin Wu, Yingrui Xu, Zhaoquan Liu, Guoqiang Du, Xiangyu Wu, Wei Liu, Rongde Wu
BACKGROUND: To observe the postoperative recovery following ureteral dilation in primary obstructive megaureter (POM) after ureteral implantation, and evaluate the risk factors affecting ureter diameter resolution. MATERIALS AND METHODS: A retrospective study was performed in patients with POM who underwent ureteral reimplantation using the Cohen procedure. Patient characteristics, perioperative parameters, and postoperative outcomes were also analysed. A widest ureteral diameter of <7 mm was defined as a normal shape and outcome...
2023: Frontiers in Pediatrics
https://read.qxmd.com/read/37408665/bilateral-proximal-ureteral-and-ureterovesical-junction-obstruction-in-a-child
#24
Daniel A Reich, Christopher E Bayne, Cynthia A Sharadin, Romano T DeMarco
The most common sites of ureteral obstruction in children are at the level of the ureteropelvic junction (UPJ) and ureterovesical junction (UVJ). Bilateral hydronephrosis or hydroureteronephrosis due to varying degrees of obstruction at the UPJ or UVJ is common in children and typically improves with time. Clinically significant obstruction at both locations in an ipsilateral ureter occurs less commonly and rarely requires both dismembered pyeloplasty and ureteral reimplantation. We believe this case report is the first description of bilateral proximal and distal ureteral obstruction requiring both dismembered pyeloplasty and ureteral reimplantation...
September 2023: Urology Case Reports
https://read.qxmd.com/read/37401687/-balloon-dilation-treatment-of-primary-obstructive-megaureter-in-children
#25
JOURNAL ARTICLE
D A Lebedev, I B Osipov, M I Komissarov, S A Sarychev, L A Alekseeva, M V Lifanova, N V Nesterova
PURPOSE: Investigation of the results of ureteral stricture single balloon dilation in children with primary obstructive megaureter. MATERIALS AND METHODS: Since 2012 to 2020 79 children (65 boys and 15 girls) with primary obstructive megaureter of II and III grades who had 92 affected ureters were operated on by method of ureteral stricture balloon dilation. Duration of postoperative stenting period was Me=68 [48; 91] days, bladder catheterization period - Me=15 [5; 61] days...
March 2023: Urologii︠a︡
https://read.qxmd.com/read/37291879/downregulation-of-fibrosis-related-hsa-mir-29c-3p-in-human-cakut
#26
JOURNAL ARTICLE
Natasa Macak, Ivan Jovanovic, Maja Zivkovic, Kristina Mitrovic, Mirjana Cvetkovic, Mirjana Kostic, Aleksandra Stankovic
Congenital anomalies of the kidney and urinary tract (CAKUT) represent structural and functional urinary system malformations and take place as one of the most common congenital malformations with an incidence of 1:500. Ureteral obstruction-induced hydronephrosis is associated with renal fibrosis and chronic kidney diseases in the pediatric CAKUT. We aimed to construct interaction network of previously bioinformatically associated miRNAs with CAKUT differentially expressed genes in order to prioritize those associated with fibrotic process and to experimentally validate the expression of selected miRNAs in CAKUT patients compared to control group...
June 8, 2023: Nucleosides, Nucleotides & Nucleic Acids
https://read.qxmd.com/read/37265149/a-single-center-study-of-the-efficacy-of-transvesicoscopic-uretero-vesical-reimplantation-with-or-without-ureteral-tailoring-in-children-with-congenital-megaureter
#27
JOURNAL ARTICLE
Han Chu, Sheng Yong Cao, Fei Qi Deng, Kun Chang Mao
OBJECTIVE: To investigate the efficacy of ureteral tailoring with or without ureteral bladder reimplantation in the treatment of primary megaureter in children by transvesicoscopic ureteral reimplantation. METHODS: The clinical data of 21 children with primary megaureter in children treated with pneumo-bladder uretero-vesical reimplantation in Anhui Children's Hospital from January 2019 to August 2022 were retrospectively analyzed. Two groups were divided according to whether intraoperative ureteral tailored was performed: 9 cases in the trimmed group and 12 cases in the no- trimmed group; 16 males and 5 females; age (4...
June 2, 2023: Journal of Endourology
https://read.qxmd.com/read/37260098/robotic-approach-to-the-uretero-vesical-junction-in-children-an-international-multicentric-retrospective-study
#28
JOURNAL ARTICLE
Francesco Molinaro, Nascimben Francesca, Camilla Todesco, Giulia Fusi, Elisa Chiarella, Tibault Planchamp, Giovanni Cobellis, Olivier Abbo, Mario Messina, Rossella Angotti
BACKGROUND: Robot-assisted approach to UVJ is getting more and more used in pediatric patients. METHODS: In this retrospective study 26 patients affected by nephro-urological malformations, robotic-surgically treated from 2016 and 2021 at 3 Pediatric Surgery Department were included: 3 (11.5%) primary obstructive megaureter, 2 (7.7%) dysplastic kidneys, 3 (11.5%) duplex collecting system, 18 (69.2%) primary vescico-ureteral reflux (VUR). RESULTS: Mean age at surgery was 6 years old...
June 1, 2023: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://read.qxmd.com/read/37088315/association-of-the-hydronephrosis-severity-score-with-likelihood-of-pyeloplasty-a-large-prospective-database-analysis
#29
JOURNAL ARTICLE
Bruce Li, Smruthi Ramesh, Melissa McGrath, Luis H Braga
OBJECTIVE: To apply and reproduce this scoring system in our prenatal hydronephrosis (PHN) population with UPJO-like HN, specifically looking at determining better HHS cutoffs that would allow for stratification into 3 risk categories: spontaneous HN resolution, observation, and surgery. METHODS: A prospectively collected prenatal hydronephrosis database was reviewed to extract UPJO-like HN patients. Children with VUR, primary megaureter, bilateral HN and other associated anomalies were excluded...
April 21, 2023: Urology
https://read.qxmd.com/read/37019712/laparoscopic-nipple-invagination-combined-extravesical-nice-reimplantation-technique-in-the-management-of-primary-obstructed-megaureter
#30
JOURNAL ARTICLE
Ramesh Babu
AIMS: Villanueva challenged Paquin's 5:1 tunnel length and showed in a computer simulation model that UVJ competence was more sensitive to a 2-mm protrusion of ureteric orifice into the bladder compared to an increase in the intravesical tunnel. Thompson later successfully applied the Shanfield technique of invaginating the spatulated primary obstructed megaureter (POM) laparoscopically, causing a nipple antireflux mechanism. In this study we have reported the outcomes of our modification: Nipple Invagination Combined Extravesical (NICE) reimplantation, in the management of POM...
March 22, 2023: Journal of Pediatric Urology
https://read.qxmd.com/read/36995462/non-surgical-management-in-children-with-non-refluxing-primary-megaureter-a-systematic-review-and-meta-analysis
#31
REVIEW
Kathrin Buder, Kathrin Opherk, Sara Mazzi, Katharina Rohner, Marcus Weitz
BACKGROUND: Children with non-refluxing primary megaureter are mostly managed by a watchful approach with close follow-up and serial imaging. OBJECTIVES: This systematic review and meta-analysis aimed to determine whether there is sufficient evidence to support the current non-surgical management strategy in these patients. DATA SOURCES: A comprehensive search including electronic literature databases, clinical trial registries, and conference proceedings was performed...
November 2023: Pediatric Nephrology
https://read.qxmd.com/read/36995132/rare-single-nucleotide-and-copy-number-variants-and-the-etiology-of-congenital-obstructive-uropathy-implications-for-genetic-diagnosis
#32
JOURNAL ARTICLE
Dina F Ahram, Tze Y Lim, Juntao Ke, Gina Jin, Miguel Verbitsky, Monica Bodria, Byum Hee Kil, Debanjana Chatterjee, Stacy E Piva, Maddalena Marasa, Jun Y Zhang, Enrico Cocchi, Gianluca Caridi, Zoran Gucev, Vladimir J Lozanovski, Isabella Pisani, Claudia Izzi, Gianfranco Savoldi, Barbara Gnutti, Valentina P Capone, William Morello, Stefano Guarino, Pasquale Esposito, Sarah Lambert, Jai Radhakrishnan, Gerald B Appel, Natalie S Uy, Maya K Rao, Pietro A Canetta, Andrew S Bomback, Jordan G Nestor, Thomas Hays, David J Cohen, Carolina Finale Na, Joanna A E van Wijk, Claudio La Scola, Olga Baraldi, Francesco Tondolo, Dacia Di Renzo, Anna Jamry-Dziurla, Alessandro Pezzutto, Valeria Manca, Adele Mitrotti, Domenico Santoro, Giovanni Conti, Marida Martino, Mario Giordano, Loreto Gesualdo, Lada Zibar, Giuseppe Masnata, Mario Bonomini, Daniele Alberti, Gaetano La Manna, Yasar Caliskan, Andrea Ranghino, Pierluigi Marzuillo, Krzysztof Kiryluk, Grażyna Krzemień, Monika Miklaszewska, Fangming Lin, Giovanni Montini, Francesco Scolari, Enrico Fiaccadori, Adela Arapović, Marijan Saraga, James McKiernan, Shumyle Alam, Marcin Zaniew, Maria Szczepańska, Agnieszka Szmigielska, Przemysław Sikora, Dorota Drożdż, Malgorzata Mizerska-Wasiak, Shrikant Mane, Richard P Lifton, Velibor Tasic, Anna Latos-Bielenska, Ali G Gharavi, Gian Marco Ghiggeri, Anna Materna-Kiryluk, Rik Westland, Simone Sanna-Cherchi
BACKGROUND: Congenital obstructive uropathy (COU) is a common cause of developmental defects of the urinary tract, with heterogeneous clinical presentation and outcome. Genetic analysis has the potential to elucidate the underlying diagnosis and help risk stratification. METHODS: We performed a comprehensive genomic screen of 733 independent COU cases, which consisted of individuals with ureteropelvic junction obstruction (UPJO; n=321), ureterovesical junction obstruction/congenital megaureter (UVJO; n=178), and congenital hydronephrosis not otherwise specified (COU-NOS; n=234)...
March 30, 2023: Journal of the American Society of Nephrology: JASN
https://read.qxmd.com/read/36902711/early-in-life-serum-aldosterone-levels-could-predict-surgery-in-patients-with-obstructive-congenital-anomalies-of-the-kidney-and-urinary-tract-a-pilot-study
#33
JOURNAL ARTICLE
Pierluigi Marzuillo, Pier Luigi Palma, Anna Di Sessa, Agnese Roberti, Giovanni Torino, Maeva De Lucia, Emanuele Miraglia Del Giudice, Stefano Guarino, Giovanni Di Iorio
The aim of the study was to evaluate whether serum aldosterone levels or plasmatic renin activity (PRA) measured early in life (1-3 months) could predict a future surgical intervention for obstructive congenital anomalies of kidney and urinary tract (CAKUT). Twenty babies aged 1-3 months of life with suspected obstructive CAKUT were prospectively enrolled. The patients underwent a 2-year follow-up and were classified as patients needing or not needing surgery. In all of the enrolled patients, PRA and serum aldosterone levels were measured at 1-3 months of life and were evaluated as predictors of surgery by receiver-operating characteristic (ROC) curve analysis...
February 28, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36869342/high-pressure-balloon-dilatation-of-primary-obstructive-megaureter-in-children-a-systematic-review
#34
JOURNAL ARTICLE
Liisi Ripatti, Hanna-Reeta Viljamaa, Anna Suihko, Niklas Pakkasjärvi
OBJECTIVE: We aimed to evaluate the effectiveness and complication rates of endoscopic high-pressure balloon dilatation (HPBD) in treating primary obstructive megaureter (POM) in children based on current literature. Specifically, we wanted to clarify the evidence on the use of HPBD in children under one year of age. METHODS: A systematic search of the literature was performed via several databases. The preferred reporting items for systematic reviews and meta-analyses guidelines were followed...
March 3, 2023: BMC Urology
https://read.qxmd.com/read/36721686/robot-assisted-extravesical-ureteral-reimplantation-with-ureteral-tailoring-and-dismembering-for-complex-obstructed-megaureter
#35
JOURNAL ARTICLE
Ciro Esposito, Lorenzo Masieri, Giuseppe Autorino, Maria Escolino
No abstract text is available yet for this article.
January 2023: Asian Journal of Urology
https://read.qxmd.com/read/36632159/minimally-invasive-ureteral-reimplantation-or-endoscopic-management-for-primary-obstructive-megaureter-a-narrative-review-of-technical-modifications-and-clinical-outcomes
#36
REVIEW
Zhenyu Li, Kunlin Yang, Xinfei Li, Silu Chen, Xiang Wang, Zhihua Li, Xuesong Li
BACKGROUND AND OBJECTIVE: Primary obstructive megaureter (POM) has various courses in different age populations. Although open ureteral reimplantation (OUR) remains the standard treatment for symptomatic POM, it is highly invasive with potential complications. In recent years, minimally invasive ureteral reimplantation (MIUR), including laparoscopic ureteral reimplantation (LUR) and robotic-assisted laparoscopic ureteral reimplantation (RALUR), and endoscopic management, such as double-J stent insertion, endoureterotomy and endoscopic balloon dilatation (EBD), have been utilized for POM in selected patients...
December 2022: Translational Andrology and Urology
https://read.qxmd.com/read/36535837/maternal-risk-factors-for-congenital-anomalies-of-the-kidney-and-urinary-tract-a-case-control-study
#37
JOURNAL ARTICLE
Raíssa T Boato, Marcos B Aguiar, Robert H Mak, Enrico A Colosimo, Ana Cristina Simões E Silva, Eduardo A Oliveira
BACKGROUND: Congenital anomalies of the kidney and urinary tract (CAKUT) are significant causes of pediatric morbidity and mortality. The spectrum of CAKUT can be part of a syndrome, but most of these abnormalities occur as isolated and sporadic forms. The etiology of human CAKUT is unknown in the majority of cases. This case-control study aimed to investigate the association between maternal characteristics and the occurrence of CAKUT and specific CAKUT phenotypes. METHODS: In this case-control study, 29,653 newborns were evaluated consecutively in a tertiary neonatal unit using the Latin American Collaborative Study of Congenital Malformations (ECLAMC) registry...
April 2023: Journal of Pediatric Urology
https://read.qxmd.com/read/36502656/a-case-of-prune-belly-syndrome-experience-from-a-regional-hospital-in-togo
#38
Tamassi Bertrand Essobiyou, Sosso Piham Kebalo, Essomondjona Pali, Alexandre Palissam Keheou, Mohamed Issa, Ekoue David Dosseh
INTRODUCTION AND IMPORTANCE: Prune Belly syndrome is a rare congenital condition first reported in 1939. It is a malformative disease associated with high mortality. We report a neonatal case in a regional hospital in Togo. PRESENTATION OF CASE: A 4-month-old male infant was brought to the hospital by his uncle because of a "deformity of the abdomen and absence of testicles". The examination revealed hypoplasia of the abdominal wall associated with bilateral cryptorchidism...
November 29, 2022: International Journal of Surgery Case Reports
https://read.qxmd.com/read/36494270/endoscopic-balloon-dilatation-for-the-treatment-of-primary-obstructive-megaureter-24%C3%A2-months-of-age-does-the-size-of-the-balloon-influence-results
#39
JOURNAL ARTICLE
Giorgia Contini, Ermelinda Mele, Nicola Capozza, Marco Castagnetti
INTRODUCTION: Endoscopic balloon dilatation (EBD) can be performed with different catheters and its durability is still controversial. This study aimed to compare long-term results of EBD performed <24 months of age using balloons of 4 mm vs. 6 mm in diameter. MATERIALS AND METHODS: Retrospective study of consecutive patients with unilateral primary obstructive megaureter (POM) undergoing EBD <24 months of age by two surgeons from 01/2009 to 12/2020...
November 24, 2022: Journal of Pediatric Urology
https://read.qxmd.com/read/36476981/use-of-temporary-double-j-stent-placement-for-children-with-congenital-hydronephrosis-a-long-term-single-center-cohort-study
#40
JOURNAL ARTICLE
Nina Hutflesz, Michael Boettcher, Susanne Deeg, Raimund Stein, Lucas M Wessel, Katrin Zahn
OBJECTIVE: To evaluate the utilization of double-J stents in children with congenital hydronephrosis in order to avoid or postpone more invasive surgical intervention. Numerous studies have demonstrated that congenital hydronephrosis caused by ureteropelvic junction obstruction (UPJO) or primary obstructive megaureter (POM) may require a surgical correction in up to 20% of cases. METHODS: All infants with severe hydronephrosis and/or an obstructive pattern on renal scintigraphy that received double-J stent placement between 2010 to 2015 in our center were analyzed...
December 4, 2022: Urology
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