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Bladder exstrophy

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https://www.readbyqxmd.com/read/28209547/pregnancy-after-urinary-diversion-at-young-ages-risks-and-outcome
#1
N Huck, S Schweizerhof, P Honeck, A Neisius, J Thüroff, R Stein
OBJECTIVE: To assess the urological and obstetric outcomes during and after pregnancy following urinary diversion (UD) performed during childhood or adolescence. PATIENTS AND METHODS: From our urinary diversion database, we identified 25 females who became pregnant between 1981 and 2013. Reasons for urinary diversion were neurogenic bladder, exstrophy, trauma, sinus urogenitalis and interstitial cystitis. 17 had continent cutaneous diversion, 4 continent anal diversion and 4 colonic conduit...
February 13, 2017: Urology
https://www.readbyqxmd.com/read/28208931/pseudo-exstrophy-of-bladder-with-unilateral-renal-agenesis-a-rare-combination-of-two-anomalies
#2
Abdolhamid Amouei, Mohammad Baghi Yazdi, Fatemeh Ehsani, Mojtaba Babaei Zarch
Pseudo-exstrophy of bladder is an uncommon condition characterized by the major musculoskeletal defects without urinary system defects. A two-day-old female neonate was presented with pseudo-exstrophy of the bladder and unilateral renal agenesis- A rare combination of two anomalies. She was born at 37 weeks gestational age with caesarean section delivery. The X-ray of hip revealed pubic diastasis. Ultrasonography clearly showed absence of the left kidney with a normal right kidney. The patient was treated successfully with proper surgical management...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28208572/re-impact-of-concomitant-hernia-repair-at-the-time-of-complete-primary-repair-of-bladder-exstrophy
#3
Douglas A Canning
No abstract text is available yet for this article.
March 2017: Journal of Urology
https://www.readbyqxmd.com/read/28208571/re-peri-operative-transfusion-risk-in-classic-bladder-exstrophy-closure-results-from-a-national-database-review
#4
Douglas A Canning
No abstract text is available yet for this article.
March 2017: Journal of Urology
https://www.readbyqxmd.com/read/28208569/re-a-critical-appraisal-of-continence-in-bladder-exstrophy-long-term-outcomes-of-the-complete-primary-repair
#5
Douglas A Canning
No abstract text is available yet for this article.
March 2017: Journal of Urology
https://www.readbyqxmd.com/read/28176844/isl1-is-a-major-susceptibility-gene-for-classic-bladder-exstrophy-and-a-regulator-of-urinary-tract-development
#6
Rong Zhang, Michael Knapp, Kentaro Suzuki, Daiki Kajioka, Johanna M Schmidt, Jonas Winkler, Öznur Yilmaz, Michael Pleschka, Jia Cao, Christina Clementson Kockum, Gillian Barker, Gundela Holmdahl, Glenda Beaman, David Keene, Adrian S Woolf, Raimondo M Cervellione, Wei Cheng, Simon Wilkins, John P Gearhart, Fabio Sirchia, Massimo Di Grazia, Anne-Karolin Ebert, Wolfgang Rösch, Jörg Ellinger, Ekkehart Jenetzky, Nadine Zwink, Wout F Feitz, Carlo Marcelis, Johannes Schumacher, Federico Martinón-Torres, Martin Lloyd Hibberd, Chiea Chuen Khor, Stefanie Heilmann-Heimbach, Sandra Barth, Simeon A Boyadjiev, Alfredo Brusco, Michael Ludwig, William Newman, Agneta Nordenskjöld, Gen Yamada, Benjamin Odermatt, Heiko Reutter
Previously genome-wide association methods in patients with classic bladder exstrophy (CBE) found association with ISL1, a master control gene expressed in pericloacal mesenchyme. This study sought to further explore the genetics in a larger set of patients following-up on the most promising genomic regions previously reported. Genotypes of 12 markers obtained from 268 CBE patients of Australian, British, German Italian, Spanish and Swedish origin and 1,354 ethnically matched controls and from 92 CBE case-parent trios from North America were analysed...
February 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28124539/one-staged-reconstruction-of-bladder-exstrophy-in-male-patients-long-term-follow-up-outcomes
#7
Amilcar Martins Giron, Marcos Figueiredo Mello, Paulo Afonso Carvalho, Paulo Renato Marcelo Moscardi, Roberto Iglesias Lopes, Miguel Srougi
INTRODUCTION: The surgical correction of bladder exstrophy remains challenging. In our institution, the repair has evolved from a staged repair to one-stage reconstruction. The one-stage reconstruction includes; bladder closure, Cantwell-Ransley neourethroplasty and abdominoplasty using groin flaps, without the need of pelvic ostheotomies. Repair of urinary continence (UC) and vesicoureteral reflux (VUR) is done after development of the infant. OBJECTIVE: To present our experience of our modified one-stage reconstruction of bladder exstrophy in male patients...
January 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28109744/adenocarcinoma-in-continent-anal-urinary-diversion-is-a-sigma-rectum-pouch-a-surgical-option-after-failed-ureterosigmoidostomy
#8
P Honeck, P Kienle, N Huck, A Neisius, J Thüroff, R Stein
OBJECTIVE: To report our experience of radical resection of secondary cancers after ureterosigmoidostomy. Ureterosigmoidostomy was the most common continent urinary diversion before the era of continent cutaneous diversion and neobladders, specifically in children. When performed for bladder exstrophy, patients have been living with this kind of diversion for quite a long time. As a result urologists are now confronted with patients presenting with an adenocarcinoma in their ureterosigmoidostomy...
January 18, 2017: Urology
https://www.readbyqxmd.com/read/28102169/hip-joint-arthroplasty-in-pubic-symphysis-separation-in-the-course-of-congenital-bladder-exstrophy-study-of-two-cases
#9
Marek Drobniewski, Andrzej Borowski, Magdalena Krasmska, Marcin Sibmski, Marek Synder
Congenital bladder exstrophy is a severe congenital malformation identified in one out of 30,000-50,000 live newborns and seen more often in girls. Some patients develop osteoarthritis of the hip joints which requires total hip arthroplasty. Reports of such cases are very rare in the world literature, which prompted us to present two cases treated at our Department and analyse their early outcomes. Our experience so far has been rather modest but the results encourage considering total hip arthroplasty in the treatment of hip osteoarthritis in future patients with pubic symphysis separation in the course of congenital bladder exstrophy...
August 30, 2016: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28058485/the-current-profile-of-persistent-cloaca-and-cloacal-exstrophy-in-japan-the-results-of-a-nationwide-survey-in-2014-and-a-review-of-the-literature
#10
Masayuki Kubota
PURPOSE: The current profile of persistent cloaca (PC) and cloacal exstrophy (CE) in Japan was first examined in 2014. MATERIALS AND METHODS: Information was obtained by sending a questionnaire to 244 university hospitals and children's hospitals. RESULTS: Responses from 113 institutions reported 466 PC cases and 229 CE cases. The incidences of PC and CE from 1980 to 2012 were 0.97 and 0.49 per 100,000 live births, respectively. In the previous 5 years, antenatal abnormalities were found in 57...
January 5, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28050437/a-rare-case-of-an-adult-with-untreated-bladder-exstrophy-presenting-with-signet-ring-cell-adenocarcinoma-of-urinary-bladder
#11
Abhishek J Savalia, Vikash Kumar, Gaurav Kasat, Ajit Sawant
Untreated bladder exstrophy in an adult is rare, as the defect is obvious and primary reconstruction is usually done in infancy. There are less than 90 reported cases of primary adenocarcinoma in an untreated bladder exstrophy in literature and only two such case reports from India. Of these, only one case was of signet-ring cell type of mucinous adenocarcinoma. Here we report the second case of signet-ring cell adenocarcinoma in a 63 year old male with untreated bladder exstrophy (oldest patient in literature), to highlight the extreme rarity, yet distinct possibility and challenges faced in surgical management of such cases...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28039050/low-dose-human-chorionic-gonadotropin-stimulation-test-as-a-prognostic-incontinent-indicator-in-boys-with-bladder-exstrophy-epispadias-complex
#12
Nastaran Sabetkish, Sahar Eftekharzadeh, Azadeh Elmi, Saman Shafaat Talab, Abdol-Mohammad Kajbafzadeh
OBJECTIVE: To investigate the effect of low-dose human chorionic gonadotropin (HCG) administration on structural changes in the lower urinary tract in boys with urinary incontinence in the setting of bladder exstrophy-epispadias complex (BEEC). PATIENTS AND METHODS: We prospectively evaluated 30 patients (median age 7.5 years) with BEEC and randomly divided them into 2 groups. Patients in the HCG group were administered 250 IU HCG intramuscularly 3 times per week during a 4-week period...
December 27, 2016: Urology
https://www.readbyqxmd.com/read/27989536/complications-of-bladder-closure-in-cloacal-exstrophy-do-osteotomy-and-reoperative-closure-factor-in
#13
Daniel A Friedlander, Heather N Di Carlo, Paul D Sponseller, John P Gearhart
BACKGROUND/PURPOSE: The aims of surgical management in cloacal exstrophy (CE) have shifted to optimizing outcomes and quality of life while minimizing morbidity. This report reviews the single-institution experience of complications of bladder closure in CE. METHODS: Patients with CE were identified from a prospectively-maintained bladder exstrophy-epispadias complex database. Operative and follow-up data were analyzed to compare complications and failure rates of bladder closure between closures performed with and without osteotomy and primary versus reoperative closures...
December 9, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27915476/translational-research-for-pediatric-lower-urinary-tract-dysfunction
#14
REVIEW
Akihiro Kanematsu
This review provides a comprehensive view of translational research aimed at elucidating the pathophysiology of pediatric lower urinary tract dysfunction (LUTD). A web search was conducted according to combinations of keywords, and the significance of each article was defined by the author. The dramatic evolution of the mass analysis method of genomes, transcripts, and proteins has enabled a comprehensive analysis of molecular events underlying diseases, and these methodologies have also been applied to pediatric LUTD...
November 2016: International Neurourology Journal
https://www.readbyqxmd.com/read/27896576/comparing-the-bulking-effect-of-calcium-hydroxyapatite-and-deflux-injection-into-the-bladder-neck-for-improvement-of-urinary-incontinence-in-bladder-exstrophy-epispadias-complex
#15
Sahar Eftekharzadeh, Nastaran Sabetkish, Shabnam Sabetkish, Abdol-Mohammad Kajbafzadeh
OBJECTIVES: The aim of this study was to evaluate the efficacy of the endoscopic injection of calcium hydroxyapatite (CaHA) into the bladder neck (BN) region of patients with urinary incontinence and bladder exstrophy-epispadias complex (BEEC). PATIENTS AND METHODS: We designed a retrospective cohort study in which we retrospectively studied medical charts of female and male patients of BEEC who had undergone CaHA or Deflux injection for continence improvement between 2009 and 2014...
November 28, 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/27890681/continent-anal-urinary-diversion-in-classic-bladder-exstrophy-45-year-experience
#16
Peter C Rubenwolf, Christian Hampel, Frederik Roos, Raimund Stein, Sebastian Frees, Joachim W Thüroff, Christian Thomas
OBJECTIVE: To evaluate the long-term outcomes in patients with classic bladder exstrophy and continent anal urinary diversion (CAD) for continence, upper urinary tract status, secondary malignancies, and sexual function. PATIENTS AND METHODS: The medical records of 82 exstrophy patients having undergone CAD in our department between 1970 and 2015 were reviewed. Patients were invited for follow-up examinations and asked to complete validated questionnaires relating to sexual function...
November 24, 2016: Urology
https://www.readbyqxmd.com/read/27889222/long-term-follow-up-of-composite-bladder-augmentation-incorporating-stomach-in-a-multi-institutional-cohort-of-patients-with-cloacal-exstrophy
#17
J T Casey, K H Chan, Y Hasegawa, T Large, B Judge, M Kaefer, R Misseri, R C Rink, K Ueoka, M P Cain
INTRODUCTION: Composite bladder augmentation, incorporating gastric and bowel segments, has the theoretical advantage of metabolic neutrality while potentially avoiding the morbidities of gastrocystoplasty, such as hematuria-dysuria syndrome. The most common indication for this operation is a paucity of bowel, such as in cloacal exstrophy. Despite several early descriptive studies of this technique, there are no reports, to date, of long-term follow-up in this population. OBJECTIVE: To describe the outcomes of composite bladder augmentation utilizing stomach in a cohort of cloacal exstrophy patients...
October 28, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27883314/diagnostic-and-surgical-approach-to-prenatally-detected-urinary-tract-anomalies
#18
Mile Petrovski
Regular ultrasound examinations carried out in the second trimester of pregnancy help in detecting many anomalies in the fetal urinary tract. Their percentage ranges from 1% to 3% of all controlled pregnancies. There is a wide spectrum of anomalies that affect the urinary tract, but the most significant are: uretero/hydronephrosis (unilateral or bilateral), kidney agenesis, dysplastic kidney, polycystic and multicystic kidneys, anomalies of ascent, anomalies of kidney rotation or fusion, bladder exstrophy, posterior urethra valve etc...
November 1, 2016: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/27802004/one-staged-reconstruction-of-bladder-exstrophy-in-male-patients-long-term-follow-up-outcomes
#19
Amilcar Martins Giron, Marcos Figueiredo Mello, Paulo Afonso Carvalho, Paulo Renato Marcelo Moscardi, Roberto Iglesias Lopes, Miguel Srougi
INTRODUCTION: The surgical correction of bladder exstrophy remains challenging. In our institution, the repair has evolved from a staged repair to one-stage reconstruction. The one-stage reconstruction includes; bladder closure, Cantwell-Ransley neourethroplasty and abdominoplasty using groin flaps, without the need of pelvic ostheotomies. Repair of urinary continence (UC) and vesicoureteral reflux (VUR) is done after development of the infant. OBJECTIVE: To present our experience of our modified one-stage reconstruction of bladder exstrophy in male patients...
January 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27781020/stem-cells-in-functional-bladder-engineering
#20
REVIEW
Jakub Smolar, Souzan Salemi, Maya Horst, Tullio Sulser, Daniel Eberli
Conditions impairing bladder function in children and adults, such as myelomeningocele, posterior urethral valves, bladder exstrophy or spinal cord injury, often need urinary diversion or augmentation cystoplasty as when untreated they may cause severe bladder dysfunction and kidney failure. Currently, the gold standard therapy of end-stage bladder disease refractory to conservative management is enterocystoplasty, a surgical enlargement of the bladder with intestinal tissue. Despite providing functional improvement, enterocystoplasty is associated with significant long-term complications, such as recurrent urinary tract infections, metabolic abnormalities, stone formation, and malignancies...
September 2016: Transfusion Medicine and Hemotherapy
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