keyword
MENU ▼
Read by QxMD icon Read
search

Osteophyte

keyword
https://www.readbyqxmd.com/read/29471516/optical-spectral-transmission-to-assess-inflammation-in-hand-and-wrist-joints-of-rheumatoid-arthritis-patients
#1
Nick J Besselink, Patricia van der Meijde, Wouter H J Rensen, Peter B L Meijer, Anne C A Marijnissen, Jacob M van Laar, Floris P J G Lafeber, Johannes W G Jacobs
Objective: To develop an optical spectral transmission (OST) model to measure joint inflammation, and thus disease activity, as well as to evaluate (patho-)physiological findings that could lead to misclassification of inflammation. Methods: Forty-six RA patients were included in this cross-sectional study, where US scores, duplicate OST measurements and 28-joint DAS (DAS28) were acquired. With US as a reference standard, the diagnostic performance of OST in detecting inflammation at the joint level was evaluated using receiver operating characteristic (ROC) curve analyses...
February 19, 2018: Rheumatology
https://www.readbyqxmd.com/read/29471377/tnf-inhibitor-treatment-is-associated-with-a-lower-risk-of-hand-osteoarthritis-progression-in-rheumatoid-arthritis-patients-after-10-years
#2
Marieke Loef, Féline P B Kroon, Sytske Anne Bergstra, Joy A van der Pol, Willem F Lems, Pit J S M Kerstens, Cornelia F Allaart, Margreet Kloppenburg
Objective: To investigate the effect of TNF inhibitors (TNFis) on incidental and progressive hand OA in recent-onset RA patients after a 10 year follow-up. Methods: Radiographs of 262 RA patients (mean age 52 years, 66% women) from the BeSt study were scored for osteophytes in DIP/PIP joints using the Osteoarthritis Research Society International atlas (0-3; summed score 0-54) and according to the Kellgren-Lawrence (KL) score (0-4; summed score 0-72) at baseline and 10 year follow-up...
February 19, 2018: Rheumatology
https://www.readbyqxmd.com/read/29470158/the-clinical-significance-of-osteophytes-in-compartments-of-the-knee-joint-with-normal-articular-cartilage
#3
B Keegan Markhardt, Geng Li, Richard Kijowski
OBJECTIVE: The purpose of this study is to determine whether marginal osteophytes in compartments with normal cartilage would be more frequently observed in knees with cartilage lesions and osteophytes in other compartments. MATERIALS AND METHODS: This retrospective study reviewed 500 consecutive knee MRI examinations performed within 6 months of arthroscopic knee surgery conducted for 497 patients with symptoms (289 male patients and 208 female patients; age range, 17-74 years; median age, 43 years)...
February 22, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29461344/confirmation-of-the-influence-of-descending-aorta-on-osteophyte-formation-in-dish
#4
Ronnie Sebro
BACKGROUND/OBJECTIVE: The aim of the study was to determine whether the location of the bridging thoracic osteophytes is related to the location of the descending thoracic aorta in patients with diffuse idiopathic skeletal hyperostosis (DISH). METHODS: This is a retrospective matched case-control study on patients treated between 2001 and 2016 at a single institution. Patients with DISH and situs inversus totalis were compared with patients with DISH and situs solitus, using 1:1 age and sex matching...
February 14, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29460078/labisia-pumila-prevented-osteoarthritis-cartilage-degeneration-by-attenuating-joint-inflammation-and-collagen-breakdown-in-postmenopausal-rat-model
#5
Iffah Nadhira Madzuki, Seng Fong Lau, Nur Adeelah Che Ahmad Tantowi, Nur Iliyani Mohd Ishak, Suhaila Mohamed
The tropical herb Labisia pumila is traditionally used in facilitating childbirth and post-partum care. The effects of L. pumila leaf extract (LP) in explant cartilage culture and on postmenopausal osteoarthritis (OA) rat model were assessed. The LP (10, 25 and 50 µg/ml) or diclofenac (10 µg/ml) was added to the cartilage explants containing bovine IL-1β (20 ng/ml), to evaluate their direct effects on cartilage degradation. In the preclinical study, rats were grouped (n = 8) into: non-treated OA; OA + diclofenac (5 mg/kg); OA + LP extract (150 and 300 mg/kg); and healthy control...
February 19, 2018: Inflammopharmacology
https://www.readbyqxmd.com/read/29457443/-diagnosis-and-treatment-of-esophagustype-cervical-spondylosis
#6
REVIEW
Hao-Lin Tan, Cheng Luo, Run Zhang, Zhi-Qing Wang, Hang Ying, Hong-Ting Jin, Pei-Jian Tong, Jin-Min Liu
Esophagustype cervical spondylosis is easily misdiagnosed or missed diagnosed for its lower incidence. The pathological basis manily concerned with compression of osteophyte for esophageal and tracheal wall and local inflammatory reaction. The diagnosis of disease is generally not difficult. Especially dynamic esophagogram could not only show degree of cervical degeneration and osteophyte shape, but also could clearly observe location and degree of osteophytosis indenting esophageal and tracheal. Recently, the treatment of esophagustype cervical spondylosis has been the focus of attention...
December 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29456980/effect-of-patellar-electrocautery-neurectomy-on-postoperative-pain-among-patients-referred-for-total-knee-arthroplasty
#7
Mehdi Motififard, Khalilollah Nazem, Aida Zarfeshani, Kaveh Zarfeshani
Background: Anterior knee pain is a major problem in total knee arthroplasty (TKA). It is accepted that anterior knee pain (AKP) often contributes to a patellofemoral etiology; however, its etiology or treatment is not understood completely. Disabling pain receptors by electrocautery could theoretically lead to anterior knee area denervation. The present study aimed to evaluate the pain post-patellar denervation (PD) with electrocautery in TKA. Materials and Methods: Clinical results for 92 patients who underwent TKA (58 women, 34 men; mean age 67...
2018: Advanced Biomedical Research
https://www.readbyqxmd.com/read/29453795/inflammatory-and-degenerative-phases-resulting-from-anterior-cruciate-rupture-in-a-non-invasive-murine-model-of-post-traumatic-osteoarthritis
#8
Sophie Jane Gilbert, Cleo Selina Bonnet, Paulina Stadnik, Victor Colin Duance, Deborah JaneMason, Emma Jane Blain
Joint injury is the predominant risk factor for post-traumatic osteoarthritis development (PTOA). Several non-invasive mouse models mimicking human PTOA investigate molecular mechanisms of disease development; none have characterised the inflammatory response to this acute traumatic injury. Our aim was to characterise the early inflammatory phase and later degenerative component in our in vivo non-invasive murine model of PTOA induced by anterior cruciate ligament (ACL) rupture. Right knees of 12-week-old C57Bl6 mice were placed in flexion at a 30° offset position and subjected to a single compressive load (12N, 1...
February 17, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29451403/assessment-of-mri-findings-and-clinical-symptoms-in-patients-with-temporomandibular-joint-disorders
#9
Risa Matsubara, Yoshinobu Yanagi, Kazuhiro Oki, Miki Hisatomi, Karina Cp Santos, Babatunde O Bamgbose, Mariko Fujita, Shunsuke Okada, Shogo Minagi, Junichi Asaumi
OBJECTIVES: To investigate the correlations among various temporomandibular joint (TMJ) findings on MRI and the relationships between MRI findings and symptoms. METHODS: 425 patients (850 TMJs) with temporomandibular joint disorders (TMDs) who underwent MRI were enrolled. Oblique sagittal proton density-weighted and T2 weighted images in open- and closed-mouth positions were evaluated. MRI findings included disc configuration, disc position, condylar morphology, bone marrow pattern, and joint effusion...
February 16, 2018: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/29447303/arthroscopic-anterior-ankle-decompression-is-successful-in-national-football-league-players
#10
Christopher L McCrum, Justin W Arner, Bryson Lesniak, James P Bradley
Anterior ankle impingement is a frequent cause of pain and disability in athletes with impingement of soft-tissue or osseous structures along the anterior margin of the tibiotalar joint during dorsiflexion. In this study, we hypothesized that arthroscopic decompression of anterior ankle impingement would result in significant, reliable, and durable improvement in pain and range of motion (ROM), and would allow National Football League (NFL) players to return to their preoperative level of play. We reviewed 29 arthroscopic ankle débridements performed by a single surgeon...
January 2018: American Journal of Orthopedics
https://www.readbyqxmd.com/read/29438856/the-surgical-management-of-dysphagia-secondary-to-diffuse-idiopathic-skeletal-hyperostosis
#11
Y C Lui Jonathan, P Sayal, G Prezerakos, V Russo, D Choi, A T H Casey
OBJECTIVE: This study reviews the management pathway and surgical outcomes of patients referred to and operated on at a tertiary neurosurgical centre, for dysphagia associated with anterolateral cervical hyperostosis (ACH) in diffuse idiopathic skeletal hyperostosis (DISH). PATIENTS & METHODS: Electronic patient records for 6 patients who had undergone anterior cervical osteophytectomy for dysphagia secondary to ACH were reviewed. ACH diagnosis was made by an Ear, Nose and Throat (ENT) specialist and patients were referred to a neurosurgical-led multidisciplinary team (MDT) for review...
February 7, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29434479/osteoarthritis-and-the-complement-cascade
#12
REVIEW
Sandeep Silawal, Jakob Triebel, Thomas Bertsch, Gundula Schulze-Tanzil
Accumulating evidence demonstrates that complement activation is involved in the pathogenesis of osteoarthritis (OA). However, the intimate complement regulation and cross talk with other signaling pathways in joint-associated tissues remain incompletely understood. Recent insights are summarized and discussed here, to put together a more comprehensive picture of complement involvement in OA pathogenesis. Complement is regulated by several catabolic and inflammatory mediators playing a key role in OA. It seems to be involved in many processes observed during OA development and progression, such as extracellular cartilage matrix (ECM) degradation, chondrocyte and synoviocyte inflammatory responses, cell lysis, synovitis, disbalanced bone remodeling, osteophyte formation, and stem cell recruitment, as well as cartilage angiogenesis...
2018: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29434267/early-changes-of-articular-cartilage-and-subchondral-bone-in-the-dmm-mouse-model-of-osteoarthritis
#13
Hang Fang, Lisi Huang, Ian Welch, Chris Norley, David W Holdsworth, Frank Beier, Daozhang Cai
To examine the early changes of articular cartilage and subchondral bone in the DMM mouse model of osteoarthritis, mice were subjected to DMM or SHAM surgery and sacrificed at 2-, 5- and 10-week post-surgery. Catwalk gait analyses, Micro-Computed Tomography, Toluidine Blue, Picrosirius Red and Tartrate-Resistant Acid Phosphatase (TRAP) staining were used to investigate gait patterns, joint morphology, subchondral bone, cartilage, collagen organization and osteoclasts activity, respectively. Results showed OA progressed over 10-week time-course...
February 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29421413/vertebral-osteophyte-as-possible-etiology-of-aorto-enteric-fistula
#14
Matthew Janko, Rocco G Ciocca, Robert I Hacker
Aortoenteric fistula (AEF) and aortoenteric erosion (AEE) are deadly and difficult to diagnose. We present here a case report of a patient with a delayed diagnosis of AEF whose preoperative imaging revealed a large vertebral osteophyte which likely directed the aortic impulse into the duodenum. We believe this is the first report documenting an anatomical explanation for AEF/AEE and conclude that the presence of vertebral osteophytes should be considered a risk factor when assessing preoperative likelihood of AEF/AEE...
February 5, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29419635/pearls-early-removal-of-posterior-osteophytes-in-tka
#15
David C Holst, Douglas A Dennis
No abstract text is available yet for this article.
February 5, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29396701/cartilage-turnover-and-intra-articular-corticosteroid-injections-in-knee-osteoarthritis
#16
Rainer Klocke, Kirsty Levasseur, George D Kitas, Jacqueline P Smith, George Hirsch
Intra-articular corticosteroid injections (IACI) are commonly used interventions for pain relief in patients with knee osteoarthritis (OA). Biomarkers may be helpful in further elucidating how IACI exert their effect. The aim of this study is to look at the response of biomarkers of cartilage and bone metabolism after IACI in knee OA. Eighty subjects with symptomatic knee OA [45% male, mean age (SD) 64 (11) years] underwent routine knee joint injection with 40 mg triamcinolone acetonide and 4 ml 1% lignocaine...
February 2, 2018: Rheumatology International
https://www.readbyqxmd.com/read/29377313/sost-sclerostin-improves-post-traumatic-osteoarthritis-and-inhibits-mmp2-3-expression-after-injury
#17
Jiun C Chang, Blaine A Christiansen, Deepa K Murugesh, Aimy Sebastian, Nicholas R Hum, Nicole M Collette, Sarah Hatsell, Aris N Economides, Craig D Blanchette, Gabriela G Loots
Patients with anterior cruciate ligament (ACL) rupture are 2X as likely to develop post traumatic osteoarthritis (PTOA). Annually, there are ∼900,000 knee injuries in the US, which account for ∼12% of all OA cases. PTOA leads to reduced physical activity, deconditioning of the musculoskeletal system and in severe cases, requires joint replacement to restore function. Therefore, treatments that would prevent cartilage degradation post injury would provide attractive alternatives to surgery. Sclerostin (Sost), a Wnt antagonist and a potent negative regulator of bone formation has recently been implicated in regulating chondrocyte function in osteoarthritis (OA)...
January 26, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29372864/beauty-parlor-stroke-syndrome-due-to-a-bone-fragment-from-an-osteophyte-of-the-atlas-case-report
#18
Takuya Kameda, Koji Otani, Takamitsu Tamura, Shinichi Konno
Beauty parlor stroke syndrome (BPSS) is a rare condition characterized by mechanical impingement of a vertebral artery (VA) during neck rotation and/or hyperextension followed by vertebrobasilar insufficiency. However, there have been no reports of BPSS in which the cause of mechanical impingement was identified and no cases for which surgical treatment was reported. The authors report the case of a 56-year-old Japanese man who presented with presyncope that occurred during cervical extension. Given the possibility of vertebrobasilar insufficiency, digital subtraction angiography and CT angiography were performed...
January 26, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29366446/estrogen-related-receptor-%C3%AE-is-a-novel-catabolic-regulator-of-osteoarthritis-pathogenesis
#19
Young-Ok Son, Jang-Soo Chun
Osteoarthritis (OA) is the most common form of arthritis and is a leading cause of disability with a large socioeconomic cost. OA is a whole-joint disease characterized by cartilage destruction, synovial inflammation, osteophyte formation, and subchondral bone sclerosis. To date, however, no effective disease-modifying therapies for OA have been developed. The estrogen-related receptors (ERRs), a family of orphan nuclear receptor transcription factors, are composed of ERRα, ERRβ, and ERRγ, which play diverse biological functions such as cellular energy metabolism...
January 25, 2018: BMB Reports
https://www.readbyqxmd.com/read/29354759/a-rare-cause-of-late-onset-neurological-deficit-in-post-tuberculous-kyphotic-deformity-case-report
#20
Suresh Subramani, Ajoy Prasad Shetty, Rishi M Kanna, Shanmuganathan Rajasekaran
Late onset neurological deficit is a rare complication of spinal tuberculosis. Reactivation of the disease and compression by internal gibbus are the common causes for late onset neurological deficit. We report a rare cause of late onset paraplegia in a patient with post tubercular kyphotic deformity. The late onset neurological deficit was due to the adjacent segment degeneration proximal to the kyphotic deformity. Posterior hypertrophied ligamentum flavum and anterior disc osteophyte complex caused the cord compression...
December 2017: Journal of Spine Surgery (Hong Kong)
keyword
keyword
37625
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"