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https://www.readbyqxmd.com/read/29038198/dysphagia-due-to-dish-related-anterior-osteophytes-dishphagia
#1
Jaslovleen Kaur, Jagandeep Singh Virk
No abstract text is available yet for this article.
October 15, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29035931/bioactive-lipids-in-osteoarthritis-risk-or-benefit
#2
Andreea Ioan-Facsinay, Margreet Kloppenburg
PURPOSE OF REVIEW: Lipids are bioactive molecules that can affect several biological functions. Technological developments allowing identification of novel lipid species and the study of their function have led to a significant advance in our understanding of lipid biology and their involvement in various diseases. This is particularly relevant for diseases associated with obesity in which lipid accumulation could be involved in pathogenesis. Here, we focus on osteoarthritis, a chronic joint disease aggravated by obesity, and will present the latest findings regarding the involvement of lipids in disease development and progression...
October 13, 2017: Current Opinion in Rheumatology
https://www.readbyqxmd.com/read/29016185/clinical-outcomes-of-knee-osteoarthritis-treated-with-an-autologous-protein-solution-injection-a-1-year-pilot-double-blinded-randomized-controlled-trial
#3
Elizaveta Kon, Lars Engebretsen, Peter Verdonk, Stefan Nehrer, Giuseppe Filardo
BACKGROUND: Osteoarthritis (OA) is a debilitating disease resulting in substantial pain and functional limitations. A novel blood derivative has been developed to concentrate both growth factors and antagonists of inflammatory cytokines, with promising preliminary findings in terms of safety profile and clinical improvement. PURPOSE: To investigate if one intra-articular injection of autologous protein solution (APS) can reduce pain and improve function in patients affected by knee OA in a multicenter, randomized, double-blind, saline-controlled study...
October 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28986227/anterior-cervical-discectomy-with-instrumented-allograft-fusion-lordosis-restoration-and-comparison-of-functional-outcomes-among-patients-of-different-age-groups
#4
Dario Muzevic, Bruno Splavski, Frederick A Boop, Kenan I Arnautovic
OBJECTIVE: To investigate clinical parameters of anterior cervical discectomy and fusion (ACDF) treatment and outcomes using osseous allograft in different age groups, study postoperative results of restoring of lordosis, and evaluate the utility of bone allografts for ACDF, including graft subsidence. METHODS: We reviewed data from 154 patients having clinical symptoms and radiological signs of disc herniation and/or cervical spondylosis. Decompression was achieved through discectomy, osteophyte ablation, endplate drilling, and foraminotomy...
October 3, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28983413/correlations-between-ultrasonographic-findings-clinical-scores-and-depression-in-patients-with-knee-osteoarthritis
#5
Samia M Abd El Monaem, Nashwa Ismail Hashaad, Noha Hosni Ibrahim
OBJECTIVE: This study aimed to explore correlations between the presence of depression, clinical scores, and ultrasonographic (US) grading in osteoarthritis (OA) patients and to clarify if depressive symptoms might cause a discrepancy between US findings and clinical scores. MATERIAL AND METHODS: Two hundred patients with primary knee OA and 100 healthy hospital volunteers of the same age and sex not complaining of knee troubles participated in this study. We evaluated depressive symptoms in all participants using the Beck Depression Inventory (BDI) scale...
September 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28983412/clinical-significance-of-matrilin-3-gene-polymorphism-in-egyptian-patients-with-primary-knee-osteoarthritis
#6
Safia M Diab, Howyda M Kamal, Amira I Mansour, Rasha M Fawzy, Basma S Azab
OBJECTIVE: Osteoarthritis (OA) is a multifactorial, degenerative, and inflammatory disorder of joints causing damage of the articular cartilage, formation of osteophytes, and eburination of the subchondral bone. Matrilin-3 (MATN-3) is a non-collagenous oligomeric extracellular matrix protein (ECM), which is the smallest member of the matrilin family. This study was conducted to identify the potential association and clinical significance of MATN-3 rs8176070 (SNP6) polymorphism in a series of Egyptian patients with primary knee OA...
September 2017: European Journal of Rheumatology
https://www.readbyqxmd.com/read/28963813/application-of-autofluorescence-robotic-histology-for-quantitative-evaluation-of-the-3-dimensional-morphology-of-murine-articular-cartilage
#7
Patricia Das Neves Borges, Tonia L Vincent, Massimo Marenzana
Murine models of osteoarthritis (OA) are increasingly important for understating pathogenesis and for testing new therapeutic approaches. Their translational potential is, however, limited by the reduced size of mouse limbs which requires a much higher resolution to evaluate their articular cartilage compared to clinical imaging tools. In experimental models, this tissue has been predominantly assessed by time-consuming histopathology using standardized semi-quantitative scoring systems. This study aimed to develop a novel imaging method for 3-dimensional (3D) histology of mouse articular cartilage, using a robotic system-termed here "3D histocutter"-which automatically sections tissue samples and serially acquires fluorescence microscopy images of each section...
September 30, 2017: Microscopy Research and Technique
https://www.readbyqxmd.com/read/28960477/real-time-ultrasound-assessment-of-astronaut-spinal-anatomy-and-disorders-on-the-international-space-station
#8
Kathleen M Garcia, Michael F Harrison, Ashot E Sargsyan, Douglas Ebert, Scott A Dulchavsky
OBJECTIVES: Back pain is one of the most common conditions of astronauts during spaceflight and is hypothesized to be attributed to pathologic anatomic changes. Ultrasound (US) represents the only available imaging modality on the International Space Station, but a formal US protocol for imaging the structures of the spinal column does not exist. This investigation developed a method of acquiring diagnostic-quality images of the anterior lumbar and cervical regions of the spine during long-duration spaceflight...
September 29, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28943421/rotational-vertebral-artery-dissection-secondary-to-an-anomalous-entrance-into-transverse-foramen-case-report
#9
Stephen A Johnson, Andrew F Ducruet, J B Bellotte, Charles E Romero, Robert M Friedlander
BACKGROUND: Rotational vertebral artery occlusion is a rare syndrome characterized by vertebrobasilar insufficiency secondary to position-dependent occlusion of the vertebral artery. Most cases reported in the literature have been attributed to osteophytic compression, either from the occipital condyle or within the transverse foramen. However, vertebral artery dissection secondary to motion in the setting of anomalous anatomy has not been reported. CASE DESCRIPTION: To the authors' knowledge, rotational vertebral artery occlusion and dissection secondary to anomalous entrance into the transverse foramen has never been reported...
September 21, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28943071/classification-of-humeral-head-pathomorphology-in-primary-osteoarthritis-a-radiographic-and-in-vivo-photographic-analysis
#10
Peter Habermeyer, Petra Magosch, Christel Weiß, Nael Hawi, Sven Lichtenberg, Mark Tauber, Bastian Ipach
BACKGROUND: The purpose of this study was to characterize the pathologic changes of the osteoarthritic humeral head. METHODS: The study included 55 patients with primary osteoarthritis who underwent anatomic shoulder arthroplasty. Several radiologic parameters (radiography, magnetic resonance imaging) were assessed. Humeral head deformity in the transverse plane and humeral cartilage erosion in the coronal plane were chosen for photographic measurements from the resected humeral heads...
September 21, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28935436/associations-between-mri-detected-early-osteophytes-and-knee-structure-in-older-adults-a-population-based-cohort-study
#11
Z Zhu, L L Laslett, W Han, B Antony, F Pan, F Cicuttini, G Jones, C Ding
OBJECTIVES: To describe prevalence of osteophytes (OPs) detected only by magnetic resonance imaging (MRI) but not by standard X-ray in older adults and to evaluate longitudinal associations with knee structural changes. METHODS: 837 participants were randomly selected from the local community and had MRI scans to assess knee OPs and other structures. OPs detected only by MRI but not by standard X-ray were defined as MRI-detected early OPs (MRI-OPs for short). OPs detected by both MRI and X-ray were defined as established-OPs...
September 19, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28935435/subchondral-tibial-bone-texture-predicts-the-incidence-of-radiographic-knee-osteoarthritis-data-from-the-osteoarthritis-initiative
#12
T Janvier, R Jennane, H Toumi, E Lespessailles
OBJECTIVES: To evaluate whether trabecular bone texture (TBT) parameters measured on computed radiographs (CR) could predict the onset of radiographic knee osteoarthritis (OA). MATERIALS AND METHODS: Subjects from the Osteoarthritis Initiative (OAI) with no sign of radiographic OA at baseline were included. Cases that developed either a global radiographic OA defined by the Kellgren-Lawrence (KL) scale, a joint space narrowing (JSN) or tibial osteophytes (TOS) were compared with the controls with no changes after 48 months of follow-up...
September 19, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28934396/evaluation-of-shared-genetic-aetiology-between-osteoarthritis-and-bone-mineral-density-identifies-smad3-as-a-novel-osteoarthritis-risk-locus
#13
Sophie Hackinger, Katerina Trajanoska, Unnur Styrkarsdottir, Eleni Zengini, Julia Steinberg, Graham R S Ritchie, Konstantinos Hatzikotoulas, Arthur Gilly, Evangelos Evangelou, John P Kemp, David Evans, Thorvaldur Ingvarsson, Helgi Jonsson, Unnur Thorsteinsdottir, Kari Stefansson, Andrew W McCaskie, Roger A Brooks, Jeremy M Wilkinson, Fernando Rivadeneira, Eleftheria Zeggini
Osteoarthritis (OA) is a common complex disease with high public health burden and no curative therapy. High bone mineral density (BMD) is associated with an increased risk of developing OA, suggesting a shared underlying biology. Here, we performed the first systematic overlap analysis of OA and BMD on a genome wide scale. We used summary statistics from the GEFOS consortium for lumbar spine (n = 31,800) and femoral neck (n = 32,961) BMD, and from the arcOGEN consortium for three OA phenotypes (hip, ncases=3,498; knee, ncases=3,266; hip and/or knee, ncases=7,410; ncontrols=11,009)...
October 1, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28933229/should-all-acromioclavicular-joint-injections-be-performed-under-image-guidance
#14
S Javed, Z Sadozai, A Javed, A Din, G Schmitgen
INTRODUCTION: Steroid and local anaesthetic injection to the acromioclavicular joint (ACJ) is a very common diagnostic and therapeutic procedure, which is often performed in the outpatient department. However, it can be difficult to localize this joint because of its small size, presence of osteophytes and variable morphology in the population. We performed a study to determine whether the use of an image intensifier (X-ray guidance), in theatre, improves the accuracy of this injection...
September 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28932491/osteophytes-removal-in-patella-versus-lateral-facetectomy-of-the-patella-in-patella-retaining-total-knee-arthroplasty
#15
Mehdi Moghtadaei, Mohammad Reza Miniator Sajadi, Hossein Farahini, Ali Yeganeh
BACKGROUND: In this study, the results of the partial lateral facetectomy of the patella to better patellofemoral motion and congruence are compared with the results of the osteophyte removal of the patella and neurectomy only in total knee arthroplasty (TKA). METHODS: Data from 55 patients undergoing TKA with osteophytes removal of the patella and neurectomy only, and those undergoing osteophytes removal of the patella and neurectomy and partial lateral facetectomy were reviewed retrospectively...
March 2017: Interventional Medicine & Applied Science
https://www.readbyqxmd.com/read/28929186/-when-is-cartilage-repair-successful
#16
REVIEW
M Raudner, M M Schreiner, S Röhrich, M Zalaudek, S Trattnig
Focal cartilage lesions are a cause of long-term disability and morbidity. After cartilage repair, it is crucial to evaluate long-term progression or failure in a reproducible, standardized manner. This article provides an overview of the different cartilage repair procedures and important characteristics to look for in cartilage repair imaging. Specifics and pitfalls are pointed out alongside general aspects. After successful cartilage repair, a complete, but not hypertrophic filling of the defect is the primary criterion of treatment success...
September 19, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28920170/meniscal-extrusion-seen-on-ultrasonography-affects-the-development-of-radiographic-knee-osteoarthritis-a-3-year-prospective-cohort-study
#17
Daisuke Chiba, Shugo Maeda, Eiji Sasaki, Seiya Ota, Shigeyuki Nakaji, Eiichi Tsuda, Yasuyuki Ishibashi
The objective of this study is to determine whether meniscal extrusion (ME) of the medial meniscus on ultrasonography affects knee osteoarthritis (KOA) progression during 3-year follow-up. Two hundred seventy volunteers (70 men, 200 women; mean age 60.5 years) participated. Weight-bearing radiographs were evaluated. All subjects had medial radiographic KOA (Kellgren-Lawrence grade [KLG], ≥ 2) in at least one knee at baseline (BL). KLG 2 was defined as moderate KOA (MKOA); KLG 3 and 4 were defined as severe KOA (SKOA)...
November 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28919498/accelerated-return-to-sport-after-acl-reconstruction-and-early-knee-osteoarthritis-features-at-1-year-an-exploratory-study
#18
Adam G Culvenor, Brooke E Patterson, Ali Guermazi, Hayden G Morris, Timothy S Whitehead, Kay M Crossley
BACKGROUND: A timely return to competitive sport is a primary goal of anterior cruciate ligament reconstruction (ACLR). It is not known if an accelerated return-to-sport increases the risk of early-onset knee osteoarthritis (KOA). OBJECTIVE: To determine whether an accelerated return-to-sport post-ACLR (i.e., <10 months) is associated with increased odds of early KOA features on MRI 1-year post-surgery, and to evaluate the relationship between an accelerated return-to-sport and early KOA features stratified by type of ACL injury (isolated or concurrent chondral/meniscal injury) and lower-limb function (good or poor)...
September 14, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28919430/role-of-subchondral-bone-properties-and-changes-in-development-of-load-induced-osteoarthritis-in-mice
#19
O O Adebayo, F C Ko, P T Wan, S R Goldring, M B Goldring, T M Wright, M C H van der Meulen
OBJECTIVE: Animal models recapitulating post-traumatic osteoarthritis (OA) suggest that subchondral bone (SCB) properties and remodeling may play major roles in disease initiation and progression. Thus, we investigated the role of SCB properties and its effects on load-induced OA progression by applying a tibial loading model on two distinct mouse strains treated with alendronate (ALN). DESIGN: Cyclic compression was applied to the left tibia of 26-week-old male C57Bl/6 (B6, low bone mass) and FVB (high bone mass) mice...
September 14, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28918594/the-association-of-knee-structural-pathology-with-pain-at-the-knee-is-modified-by-pain-at-other-sites-in-those-with-knee-osteoarthritis
#20
Feng Pan, Jing Tian, Dawn Aitken, Flavia Cicuttini, Tania Winzenberg, Graeme Jones
The objective of this study was to investigate the associations of knee structural abnormalities with different patterns of pain. A total of 891 participants (average age 63 years; range 50 to 80 years) participated in this study. Presence of pain at the neck, back, hands, shoulders, hips, knees, and feet was assessed by questionnaire. Participants were categorized as having no pain at any site (no pain), pain only at the knee (KP), pain at other sites but not the knee (OP), and pain at the knee and other sites (KOP)...
November 2017: Clinical Rheumatology
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