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https://www.readbyqxmd.com/read/29759020/corrigendum
#1
(no author information available yet)
ISFM Consensus Guidelines on the Diagnosis and Management of Hypertension in Cats Samantha S Taylor, Andrew H Sparkes, Katherine Briscoe, Jenny Carter, Salva Cervantes Sala, Rosanne E Jepson, Brice S Reynolds and Brian A Scansen J Feline Med Surg 2017; 19: 288-303 Readers should note that the version of the guidelines that appeared in print in March 2017 and online until May 2018 has been amended. The version now appearing online is the correct one. For information, the following amendment has been made to the original published version...
May 1, 2018: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29724305/-effects-of-continuous-intravenous-intraoperative-lidocaine-infusion-on-opioids-consumption-and-postoperative-recovery-in-patients-undergoing-video-assisted-thoracoscopic-lobectomy
#2
Zi Jia Liu, Liang Yan Zhang, Xu Guang Zheng, Le Shen, Kai Cheng Song, Jie Yi, Yu Guang Huang
Objective To investigate whether continuous intravenous intraoperative lidocaine infusion can reduce the opioids dosage and improve postoperative recovery in patients undergoing video-assisted thoracoscopic(VATS) lobectomy. Methods Totally 60 patients undergoing VATS lobectomy were enrolled in this single-center randomized controlled study.The patients were equally randomized into lidocaine continuous pumping group(lidocaine group) and control group by computer-based random numbers.The patients had double-lumen catheter intubation,and total intravenous anesthesia was administrated intraoperatively...
April 28, 2018: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/29670896/short-term-treatment-with-esmolol-reverses-left-ventricular-hypertrophy-in-adult-spontaneously-hypertensive-rats-via-inhibition-of-akt-nf-%C3%AE%C2%BA-b-and-nfatc4
#3
Begoña Quintana-Villamandos, David A Goukassian, Sharath P Sasi, Emilio Delgado-Baeza
Our group has previously demonstrated that short-term treatment with esmolol reduces left ventricular hypertrophy (LVH) in spontaneously hypertensive rats (SHRs). The present study aimed to assess the molecular mechanisms related to this effect. Fourteen-month-old male SHRs were treated intravenously with saline as vehicle (SHR) or esmolol (SHR-E) (300  μ g/kg/min). Age-matched vehicle-treated male Wistar-Kyoto (WKY) rats served as controls. After 48 hours of treatment, the hearts were harvested and left ventricular tissue was separated and processed for Western blot analysis to determine the levels of Akt, NF- κ B, NFATc4, Creb1, Serca2a, Erk1/2, and Sapk/Jnk...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29665297/esmolol-acutely-alters-oxygen-supply-demand-balance-in-exercising-muscles-of-healthy-humans
#4
David N Proctor, J Carter Luck, Stephan R Maman, Urs A Leuenberger, Matthew D Muller
Beta-adrenoreceptor antagonists (β blockers) reduce systemic O2 delivery and blood pressure (BP) during exercise, but the subsequent effects on O2 extraction within the active limb muscles are unknown. In this study, we examined the effects of the fast-acting, β1 selective blocker esmolol on systemic hemodynamics and leg muscle O2 saturation (near infrared spectroscopy, NIRS) during submaximal leg ergometry. Our main hypothesis was that esmolol would augment exercise-induced reductions in leg muscle O2 saturation...
April 2018: Physiological Reports
https://www.readbyqxmd.com/read/29628593/comparison-of-esmolol-and-dexmedetomidine-for-suppression-of-hemodynamic-response-to-laryngoscopy-and-endotracheal-intubation-in-adult-patients-undergoing-elective-general-surgery-a-prospective-randomized-controlled-double-blinded-study
#5
Sandeep Sharma, Om Prakash Suthar, M L Tak, Abhilasha Thanvi, Naveen Paliwal, Rakesh Karnawat
Context: Laryngoscopy and endotracheal intubation lead to strong sympathetic response which may precipitate arrhythmias, myocardial ischemia and cerebrovascular accidents in patients with preexisting cardiovascular disease. Aims: This study was aimed to compare the effect of dexmedetomidine and esmolol on hemodynamic response to laryngoscopy and endotracheal intubation in patients undergoing elective surgery under general anesthesia. Settings and Design: This was a prospective, randomized controlled double-blinded study...
January 2018: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29628578/attenuation-of-hemodynamic-response-to-tracheal-extubation-a-comparative-study-between-esmolol-and-labetalol
#6
H S Prajwal Patel, M R Shashank, B T Shivaramu
Background and Aims: Cardiovascular stress response to extubation can result in elevated heart rate (HR) and mean arterial blood pressures which can be detrimental in high-risk patients. Settings and Design: The objective of this study is to compare the esmolol and labetalol efficacy in attenuating hemodynamic response to tracheal extubation. Materials and Methods: Sixty patients scheduled for elective surgical procedures were selected randomly and divided into two groups of thirty each...
January 2018: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29628560/effect-of-esmolol-and-diltiazem-infusions-on-hemodynamic-response-to-pneumoperitoneum-on-laparoscopic-simple-nephrectomy-a-randomized-controlled-trial
#7
Alka Verma, Divya Srivastava, Mekhala Paul, Arindam Chatterjee, Abhilash Chandra
Background: Several studies have been conducted in search of appropriate drugs to attenuate hemodynamic responses in laparoscopic cholecystectomy, but till date, no such study has been conducted on patients undergoing laparoscopic nephrectomy. Aim: The study was designed to assess the effect of esmolol and diltiazem infusions on hemodynamic changes during routine laparoscopic transperitoneal simple nephrectomy. Settings and Design: A prospective double-blinded randomized control trial...
January 2018: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29620652/use-of-low-dose-neostigmine-intravenously-in-the-treatment-of-thyroid-storm-induced-severe-tachycardia-in-patient-during-huge-pelvic-mass-resection-a-case-report-and-review-of-literature
#8
Xue Zhang, Hui Jiang, Shiyong Li, Ailin Luo, Yilin Zhao
RATIONALE: Thyroid storm is a rare and life-threatening metabolic crisis because of an emergent release of excess thyroid hormone. Sinus tachycardia induced by excess thyroid hormone may result in congestive heart failure due to decreased diastolic filling time. PATIENT CONCERNS: A controlled hyperthyroidism patient with severe sinus tachycardia. DIAGNOSES: A controlled hyperthyroidism patient was induced thyroid storm during huge pelvic mass resection...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29600897/influence-of-myocardial-oxygen-demand-on-the-coronary-vascular-response-to-arterial-blood-gas-changes-in-humans
#9
Tyler Dennis Vermeulen, Lindsey M Boulet, Mike Stembridge, Alexandra Mackenzie Williams, James D Anholm, Prajan Subedi, Chris Gasho, Philip N Ainslie, Eric O Feigl, Glen Edward Foster
It remains unclear if the human coronary vasculature is inherently sensitive to changes in arterial PO2 and PCO2 or if coronary vascular responses are the result of concomitant increases in myocardial O2 consumption/demand (MVO2 ). We hypothesized that the coronary vascular response to PO2 and PCO2 would be attenuated in healthy men when MVO2 was attenuated with β1 -adrenergic receptor blockade. Healthy men (n=11; age: 25 {plus minus} 1 years) received intravenous esmolol (β1 -adrenergic receptor antagonist) or volume-matched saline in a double-blind, randomized, crossover study, and were exposed to poikilocapnic hypoxia, isocapnic hypoxia, and hypercapnic hypoxia...
March 30, 2018: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29554644/radioiodinated-esmolol-as-a-highly-selective-radiotracer-for-myocardial-perfusion-imaging-in-silico-study-and-preclinical-evaluation
#10
Tamer M Sakr, M H Sanad, Walaa H Abd-Alla, Dina H Salama, Gehan M Saleh
Challenges facing cardiovascular imaging necessitate innovation of better radiopharmaceuticals to augment or replace the existing ones. This research assesses the ability and competency of radioiodinated esmolol as a potential cardio selective imaging agent. Radioiodinated esmolol was synthesized with 97.3 ± 0.3% radiochemical yield and with high stability up to 48 h at room temperature as well as in rat serum. Molecular modeling study was performed to confirm the binding of iodinated esmolol to β1 -adrenergic receptor...
March 9, 2018: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/29504986/impending-thyroid-storm-in-a-pregnant-woman-with-undiagnosed-hyperthyroidism-a-case-report-and-literature-review
#11
REVIEW
Yushan Ma, Hao Li, Jin Liu, Xuemei Lin, Hui Liu
RATIONALE: Thyroid storm is a rare complication during caesarean section of patients with hyperthyroidism. It occurs abruptly, with a high mortality rate if not recognized immediately and aggressively treated. Herein, we reported a case of impending thyroid storm during a caesarean section. PATIENT CONCERNS: A healthy 23-year-old woman with undiagnosed hyperthyroidism underwent an emergency caesarean section under general anesthesia. After tracheal extubation, the patient exhibited abnormal tachycardia, agitation, sweating, and hyperpyrexia...
January 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29470800/landiolol-a-review-in-tachyarrhythmias
#12
Yahiya Y Syed
Intravenous landiolol [Rapibloc® (EU)], an ultra short-acting highly cardioselective β1 -blocker, is approved in the EU for the rapid short-term control of tachyarrhythmias in the perioperative and intensive care settings. It has long been used in Japan to treat perioperative tachyarrhythmias. The efficacy of landiolol has been demonstrated in a large number of randomized controlled clinical trials. Landiolol significantly reduced heart rate in patients with postoperative or intraoperative supraventricular tachycardia relative to placebo and in those with atrial fibrillation/flutter and left ventricular dysfunction relative to digoxin...
March 2018: Drugs
https://www.readbyqxmd.com/read/29464441/left-heart-pressures-can-be-the-key-to-know-the-limitation-of-left-ventricular-assist-device-support-against-progression-of-aortic-insufficiency
#13
Kei Iizuka, Tomohiro Nishinaka, Noritsugu Naito, Daichi Akiyama, Yoshiaki Takewa, Kenji Yamazaki, Eisuke Tatsumi
Aortic insufficiency (AI) is a worrisome complication under left ventricular assist device (LVAD) support. AI progression causes LVAD-left ventricular (LV) recirculation and can require surgical intervention to the aortic valve. However, the limitations of LVAD support are not well known. Using an animal model of LVAD with AI, the effect of AI progression on hemodynamics and myocardial oxygen metabolism were investigated. Five goats (Saanen 48 ± 2 kg) underwent centrifugal type LVAD, EVAHEART, implantation...
February 20, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29441909/the-effect-of-continuous-perfusion-of-esmolol-on-cardiovascular-risk-in-elderly-patients-undergoing-noncardiac-surgery
#14
X K Zhang, Q Hu, Q H Chen, W X Wang
We evaluated the effect of continuous perfusion of esmolol on cardiovascular risk during curative laparoscopic surgery for gastrointestinal cancer in elderly patients. Sixty patients with gastrointestinal cancer, aged from 60 to 80 years, were divided into an esmolol group (ES, n = 30) and a control group (NS, n = 30). ES patients were treated with esmolol at a dose of 0.3 mg/kg 3 min before tracheal intubation, and received continuous perfusion of esmolol at a dose of 50 μg/kg/min during operation. In NS, esmolol was replaced by saline...
August 1, 2017: Die Pharmazie
https://www.readbyqxmd.com/read/29398384/ultra-short-acting-%C3%AE-blockers-esmolol-and-landiolol-in-the-perioperative-period-and-in-critically-ill-patients
#15
REVIEW
Ricardo Poveda-Jaramillo, Fabrizio Monaco, Alberto Zangrillo, Giovanni Landoni
β-Blockers are useful drugs in several clinical cardiologic scenarios. Their use in the perioperative period and in critically ill patients is increasing, but their effect on clinically relevant outcomes remains controversial. Long-acting β-blockers can have detrimental effects that are difficult to be counteracted in these settings. The authors describe the possible clinical uses of ultra-short-acting β-blockers (esmolol and landiolol) in the perioperative period and in critically ill patients because these drugs have the beneficial effects of β-blockers, but do not have the detrimental effects of long-acting agents...
November 23, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29394143/left-ventricle-function-during-therapeutic-hypothermia-with-beta-1-adrenergic-receptor-blockade
#16
Harald A Bergan, Per S Halvorsen, Andreas Espinoza, Viesturs Kerans, Helge Skulstad, Erik Fosse, Jan F Bugge
Therapeutic hypothermia is an established treatment in patients resuscitated from cardiac arrest. It is usually well-tolerated circulatory, but hypothermia negatively effects myocardial contraction and relaxation velocities and increases diastolic filling restrictions. A significant proportion of resuscitated patients are treated with long-acting beta-receptor blocking agents' prearrest, but the combined effects of hypothermia and beta-blockade on left ventricle (LV) function are not previously investigated...
February 2, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29332839/magnetic-solid-phase-extraction-based-on-magnetic-multiwalled-carbon-nanotubes-for-the-simultaneous-enantiomeric-analysis-of-five-%C3%AE-blockers-in-the-environmental-samples-by-chiral-liquid-chromatography-coupled-with-tandem-mass-spectrometry
#17
Zhaokun Wang, Xue Zhang, Shenmeng Jiang, Xingjie Guo
In this work, the magnetic multiwalled carbon nanotubes (Mag-MWCNTs) were prepared by self-assembly method and characterized by scanning electron microscopy, X-ray powder diffraction, energy dispersive X-ray and vibrating sample magnetometer. Then, these synthetic Mag-MWCNTs were used as sorbents to extract five β-blockers (atenolol, metoprolol, esmolol, pindolol and arotinolol) by magnetic solid-phase extraction. The target analytes adsorbed on Mag-MWCNTs were eluted and determined on a chiral α-acid glycoprotein column coupled with a triple quadrupole mass spectrometry...
April 1, 2018: Talanta
https://www.readbyqxmd.com/read/29319439/successful-management-of-minoxidil-toxicosis-in-a-dog
#18
Tyler J M Jordan, Page E Yaxley, Christine A Culler, Anusha Balakrishnan
CASE DESCRIPTION A 2-year-old sexually intact female mixed-breed dog was evaluated at an emergency hospital approximately 5 hours after ingestion of an unknown amount of over-the-counter topical hair growth promoter containing 5% minoxidil foam. Vomiting and signs of lethargy were reported by the owner, and physical examination revealed tachycardia and hypotension. No treatments were performed, and the dog was transferred to a veterinary referral hospital for management of suspected minoxidil toxicosis. CLINICAL FINDINGS On arrival at the referral hospital, the dog was tachycardic (heart rate, 200 to 220 beats/min) and hypotensive (systolic arterial blood pressure, 70 mm Hg)...
January 15, 2018: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29284847/evaluation-of-preoperative-flupirtine-in-ambulatory-functional-endoscopic-sinus-surgery-a-prospective-double-blind-randomized-controlled-trial
#19
Anjan Das, Hirak Biswas, Anindya Mukherjee, Sandip Roy Basunia, Subinay Chhaule, Tapobrata Mitra, Partha Sarathi Halder, Subrata Kumar Mandal
Background: Functional endoscopic sinus surgery (FESS) is the mainstay therapeutic management for nasal pathologies. We evaluated flupirtine, a centrally acting analgesic, for producing perfect perioperative conditions in FESS for adults in a day-care setting. Materials and Methods: Sixty-two patients (25-40 years) scheduled for FESS under general anesthesia were randomly divided into Group F ( n = 31) receiving preoperative flupirtine (100 mg) and Group C ( n = 31) receiving identical-looking placebo capsule per oral 60 min before induction of anesthesia...
October 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29233190/microvascular-effects-of-intravenous-esmolol-in-patients-with-normal-cardiac-function-undergoing-postoperative-atrial-fibrillation-a-prospective-pilot-study-in-cardiothoracic-surgery
#20
William Fornier, Matthias Jacquet-Lagrèze, Thomas Collenot, Priscilla Teixeira, Philippe Portran, Rémi Schweizer, Michel Ovize, Jean-Luc Fellahi
BACKGROUND: Postoperative atrial fibrillation (POAF) is commonplace after cardiothoracic surgery. A rate control strategy using short-acting beta blockers is recommended as a first-line therapy in patients without hemodynamic instability. Microcirculatory effects of POAF and esmolol have not yet been investigated. We hypothesized that POAF without hemodynamic instability would induce microvascular dysfunction which could be reversed by intravenous esmolol. METHODS: Twenty-five cardiothoracic surgical patients with POAF were included in the study...
December 12, 2017: Critical Care: the Official Journal of the Critical Care Forum
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