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https://www.readbyqxmd.com/read/28548990/outbreaks-of-nontuberculous-mycobacteria
#1
Geeta Sood, Nikki Parrish
PURPOSE OF REVIEW: The purpose of this review is to summarize the emerging literature on nontuberculous mycobacteria outbreaks in healthcare settings. As our ability to identify mycobacterial species develops, we are better able to recognize epidemiologic connections and better understand the prevalence and importance of these outbreaks and pseudo-outbreaks in healthcare settings. RECENT FINDINGS: The number of outbreaks related to nontuberculous outbreaks is increasing because of heightened awareness and better diagnostic tests for species level identification of mycobacteria...
May 25, 2017: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/28527358/improving-the-pharmacokinetics-and-tissue-distribution-of-pyrinezolid-by-self-assembled-polymeric-micelles
#2
Haiyue Long, Xiaoling Li, Zitai Sang, Lan Mei, Tao Yang, Zicheng Li, Liangxue Zhou, Yu Zheng, Gu He, Gang Guo, Zhenling Wang, Yong Deng, Youfu Luo
Antibiotic-resistance by bacteria is a growing global concern within the healthcare field, and it has provided an impetus for continued antimicrobial development. Pyrinezolid (PZ), a novel oxazolidinone compound, can effectively inhibit most gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE). Though PZ is a promising antimicrobial candidate, the druggability of PZ is limited by its poor water solubility. Therefore, the amphipathic mPEG-PLLA copolymer was used to prepare the pyrinezolid micelles (PZ-M)...
May 8, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28516821/pseudomonas-aeruginosa-outbreak-in-a-neonatal-intensive-care-unit-attributed-to-hospital-tap-water
#3
Cara Bicking Kinsey, Samir Koirala, Benjamin Solomon, Jon Rosenberg, Byron F Robinson, Antonio Neri, Alison Laufer Halpin, Matthew J Arduino, Heather Moulton-Meissner, Judith Noble-Wang, Nora Chea, Carolyn V Gould
OBJECTIVE To investigate an outbreak of Pseudomonas aeruginosa infections and colonization in a neonatal intensive care unit. DESIGN Infection control assessment, environmental evaluation, and case-control study. SETTING Newly built community-based hospital, 28-bed neonatal intensive care unit. PATIENTS Neonatal intensive care unit patients receiving care between June 1, 2013, and September 30, 2014. METHODS Case finding was performed through microbiology record review. Infection control observations, interviews, and environmental assessment were performed...
May 18, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28510692/disseminated-neonatal-herpes-simplex-virus-type-1-after-a-water-birth
#4
Niazy Al-Assaf, Heather Moore, Kirk Leifso, Nadya Ben Fadel, Emanuela Ferretti
Neonatal herpes simplex virus (NHSV) infections are associated with significant morbidity and mortality. Numerous factors influence the transmission of HSV infection to newborns; however, immersion in water during labor has received very little attention as a possible risk factor despite the increasing popularity of water births. We report a case of disseminated NHSV type 1 infection, possibly acquired during a water birth. The purpose of this report is to alert healthcare providers to this potential route of transmission and to highlight the importance of screening guidelines for HSV before a water birth...
May 16, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28509659/reasons-for-transferring-hiv-care-in-london
#5
Nadia Ahmed, Duncan Scott, Nasha Matin, Laura Waters, Gary Whitlock
People living with HIV in England, as well as non-UK born and individuals without residency, can access free HIV care at any service in England. We investigated reasons for transfer of care to three London HIV units by asking all patients transferring to fill in a questionnaire exploring reasons for leaving their previous centre and reasons for choosing the new service. A total of 111 patients completed the questionnaire. The majority of patients transferred from abroad to London HIV units, compared to within the UK...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28501881/-medicaments-and-oral-healthcare-4-pharmacotherapy-in-frail-and-care-dependent-older-people
#6
C de Baat, G J van der Putten, A Visser, A Vissink
Polypharmacy is the consequence of multimorbidity. Both phenomena may cause functional limitations and/or frailty and/or care dependency in older people. In the human body, a medicament undergoes at least 3 important actions: absorption, distribution and elimination. These actions may proceed aberrantly in older people. Following interaction with receptors, a medicament triggers a chain reaction in the human body. The receptors and each link of the chain reaction may be subject to changes due to diseases as well as ageing...
May 2017: Nederlands Tijdschrift Voor Tandheelkunde
https://www.readbyqxmd.com/read/28490470/metal-artifact-reduction-of-ct-scans-to-improve-pet-ct
#7
Charlotte S van der Vos, Anne Ij Arens, Jim Hamill, Christian Hofmann, Vladimir Y Panin, Antoi Pw Meeuwis, Eric P Visser, Lioe-Fee de Geus-Oei
In recent years different metal artifact reduction (MAR) methods have been developed for computed tomography (CT). These methods have only recently been introduced for positron emission tomography/computed tomography (PET/CT) even though they could be beneficial for interpretation, segmentation and quantification of the PET/CT images. In this study, phantom and patient scans were analyzed visually and quantitatively to measure the effect on PET images of iterative metal artifact reduction (iMAR) of CT data...
May 10, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28486169/characterization-of-oxa-48-like-producing-enterobacteriaceae-isolated-from-river-water-in-algeria
#8
Rima Tafoukt, Abdelaziz Touati, Thongpan Leangapichart, Sofiane Bakour, Jean-Marc Rolain
The spread of carbapenemase-producing Enterobacteriaceae (CPE) is a significant problem for healthcare worldwide. The prevalence of carbapenem-resistant Enterobacteriaceae (CPE) in water environments in Algeria are unknown. The aim of this study was to screen for the presence of CPE isolates in the Soummam River in Bejaia, Algeria. Isolates of Enterobacteriaceae recovered from twelve samples of river water and showing reduced susceptibility to carbapenems were included in this study. The isolates were identified by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS)...
April 30, 2017: Water Research
https://www.readbyqxmd.com/read/28482836/assessment-of-herbal-drugs-for-promising-anti-candida-activity
#9
Sameh S M Soliman, Mohammad H Semreen, Ali A El-Keblawy, Arbab Abdullah, Priya Uppuluri, Ashraf S Ibrahim
BACKGROUND: Microbial infections are diverse and cause serious human diseases. Candida albicans infections are serious healthcare-related infections that are complicated by its morphological switching from yeast to hyphae, resistant biofilm formation and mixed infections with bacteria. Due to the increase in drug resistance to currently used antimicrobial agents and the presence of undesirable side effects, the need for safe and effective novel therapies is important. Compounds derived from plants are known for their medicinal properties including antimicrobial activities...
May 8, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28482478/supramolecular-system-of-podophyllotoxin-and-hydroxypropyl-%C3%AE-cyclodextrin-characterization-inclusion-mode-docking-calculation-solubilization-stability-and-cytotoxic-activity
#10
Li-Juan Yang, Shu-Hui Wang, Shu-Ya Zhou, Fang Zhao, Qing Chang, Min-Yan Li, Wen Chen, Xiao-Dong Yang
The inclusion complexation behavior, characterization, and inclusion mode of podophyllotoxin (POD) with hydroxypropyl-β-cyclodextrin (HPβCD) were investigated in both solution and the solid state by means of XRD, DSC, SEM, (1)H and 2D NMR and UV-vis spectroscopy. The results showed that the water solubility and thermal stability of POD were obviously increased in the inclusion complex with HPβCD. The cytotoxicity of POD/HPβCD inclusion complex against all the human tumor cell lines investigated still remains...
July 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28466937/transparent-flexible-and-stretchable-ws2-based-humidity-sensors-for-electronic-skin
#11
Huayang Guo, Changyong Lan, Zhifei Zhou, Peihua Sun, Dapeng Wei, Chun Li
Skin-mountable chemical sensors using flexible chemically sensitive nanomaterials are of great interest for electronic skin (e-skin) application. To build these sensors, the emerging atomically thin two-dimensional (2D) layered semiconductors could be a good material candidate. Herein, we show that a large-area WS2 film synthesized by sulfurization of a tungsten film exhibits high humidity sensing performance both in natural flat and high mechanical flexible states (bending curvature down to 5 mm). The conductivity of as-synthesized WS2 increases sensitively over a wide relative humidity range (up to 90%) with fast response and recovery times in a few seconds...
May 18, 2017: Nanoscale
https://www.readbyqxmd.com/read/28466601/adult-extracorporeal-membrane-oxygenation-an-international-survey-of-transfusion-and-anticoagulation-techniques
#12
S A Esper, I J Welsby, K Subramaniam, W John Wallisch, J H Levy, J H Waters, D J Triulzi, J W A Hayanga, G J Schears
BACKGROUND AND OBJECTIVES: Extracorporeal membrane oxygenation (ECMO) is a method of life support for either isolated cardiac failure or respiratory failure, with or without cardiac failure. When used for hemodynamic support, the ECMO circuit presents a non-endothelialized, artificial surface to blood inciting an inflammatory response which activates haemostatic pathways. Anticoagulation may complicate a pre-existing coagulopathy and/or inadequate surgical hemostasis of varying severity...
May 3, 2017: Vox Sanguinis
https://www.readbyqxmd.com/read/28423996/assessing-user-acceptance-towards-automated-and-conventional-sink-use-for-hand-decontamination-using-the-technology-acceptance-model
#13
Carolyn H Dawson, Jamie B Mackrill, Rebecca Cain
Hand hygiene (HH) prevents harmful contaminants spreading in settings including domestic, health care and food handling. Strategies to improve HH range from behavioural techniques through to automated sinks that ensure hand surface cleaning. This study aimed to assess user experience and acceptance towards a new automated sink, compared to a normal sink. An adapted version of the technology acceptance model (TAM) assessed each mode of handwashing. A within-subjects design enabled N = 46 participants to evaluate both sinks...
April 24, 2017: Ergonomics
https://www.readbyqxmd.com/read/28420404/development-of-a-spatial-sampling-protocol-using-gis-to-measure-health-disparities-in-bobo-dioulasso-burkina-faso-a-medium-sized-african-city
#14
Daouda Kassié, Anna Roudot, Nadine Dessay, Jean-Luc Piermay, Gérard Salem, Florence Fournet
BACKGROUND: Many cities in developing countries experience an unplanned and rapid growth. Several studies have shown that the irregular urbanization and equipment of cities produce different health risks and uneven exposure to specific diseases. Consequently, health surveys within cities should be carried out at the micro-local scale and sampling methods should try to capture this urban diversity. METHODS: This article describes the methodology used to develop a multi-stage sampling protocol to select a population for a demographic survey that investigates health disparities in the medium-sized city of Bobo-Dioulasso, Burkina Faso...
April 18, 2017: International Journal of Health Geographics
https://www.readbyqxmd.com/read/28417600/a-bioinspired-mineral-hydrogel-as-a-self-healable-mechanically-adaptable-ionic-skin-for-highly-sensitive-pressure-sensing
#15
Zhouyue Lei, Quankang Wang, Shengtong Sun, Wencheng Zhu, Peiyi Wu
In the past two decades, artificial skin-like materials have received increasing research interests for their broad applications in artificial intelligence, wearable devices, and soft robotics. However, profound challenges remain in terms of imitating human skin because of its unique combination of mechanical and sensory properties. In this work, a bioinspired mineral hydrogel is developed to fabricate a novel type of mechanically adaptable ionic skin sensor. Due to its unique viscoelastic properties, the hydrogel-based capacitive sensor is compliant, self-healable, and can sense subtle pressure changes, such as a gentle finger touch, human motion, or even small water droplets...
April 18, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28395091/morbidity-among-the-israeli-defense-force-response-team-during-nepal-post-earthquake-mission-2015
#16
Tamar Lachish, Aviad Bar, Heli Alalouf, Ofer Merin, Eli Schwartz
Background: On 25 April 2015, a 7.8-magnitude earthquake struck Nepal. Soon after, the Israel Defense Force (IDF) dispatched a rapid-response team and opened a tertiary field hospital in Kathmandu. There is limited data regarding the spectrum of diseases among rescue teams to disease-stricken areas. The aim of this study was to assess the morbidity among the field-hospital staff during the mission. Methods: The rescue team was deployed for a 2-week mission in Kathmandu...
March 1, 2017: Journal of Travel Medicine
https://www.readbyqxmd.com/read/28393678/children-s-perspectives-in-family-centred-hospital-care
#17
Shayne Rasmussen, Tineke Water, Annette Dickinson
BACKGROUND: Children's nursing has developed into its current forms in large part as a result of broader socio-political and organisational influences. Family-centred, patient centred and collaborative approaches are now well established within the lexicon of child healthcare. Children are central to this yet their role within the family-centred care approach is not clear. AIM: To ask children to share the narratives of their experience of hospitals and hospitalisation in New Zealand, in order to consider multiple factors influencing their experience in hospital...
April 10, 2017: Contemporary Nurse
https://www.readbyqxmd.com/read/28392599/a-call-to-promote-healthcare-justice-a-summary-of-integrated-outpatient-clinics-exemplifying-principles-of-catholic-social-teaching
#18
Nicole P Waters, Trenton Schmale, Allison Goetz, Jason T Eberl, Jessica H Wells
There is an urgent need to promote healthcare justice for patients as well as members of the healthcare team including physicians. In this article, we explain how principles of Catholic social teaching (i.e., dignity of the individual, common good, destination of goods, solidarity, and subsidiarity) are applied to health care, by featuring various types of outpatient clinics including free, charitable-direct primary care, hybrid, federally qualified health center, and rural health clinic. We describe how attempts have been made to improve the quality and access of health care by creating new medical schools (i...
February 2017: Linacre Quarterly
https://www.readbyqxmd.com/read/28390462/does-the-texas-first-dental-home-program-improve-parental-oral-care-knowledge-and-practices
#19
Charmaine L Thompson, Ann L McCann, Emet D Schneiderman
PURPOSE: This study evaluated the effectiveness of the Texas Medicaid First Dental Home (FDH) by comparing the oral health knowledge, practices, and opinions of participating vs. non-participating parents. METHODS: A 29-question survey (English & Spanish) was developed and administered to 165 parents of children under three years old (FDH=49, Non-FDH=116) who visited qualifying Medicaid clinics in Texas. RESULTS: Mann Whitney U tests showed that FDH parents scored higher on overall knowledge (P=0...
March 15, 2017: Pediatric Dentistry
https://www.readbyqxmd.com/read/28389093/risk-factors-for-kpc-producing-enterobacteriaceae-acquisition-and-infection-in-a-healthcare-setting-with-possible-local-transmission-a-case-control-study
#20
K M Cronin, Y S Poy Lorenzo, M E Olenski, A E Bloch, K Visvanathan, M J Waters, K L Buising
BACKGROUND: Reports of Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-Kp) in Australia were previously uncommon, with cases imported sporadically by travellers from higher prevalence countries. AIM: The study institution reported the first outbreak of KPC-Kp in Australia. The aim of this study was to identify risk factors for KPC-Kp colonization and infection using a matched case-control study. METHODS: The study included all hospitalized patients with KPC-Kp colonization or infection from January 2012 to September 2015...
February 16, 2017: Journal of Hospital Infection
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