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https://www.readbyqxmd.com/read/29211780/prevalence-and-antibiotic-resistance-of-pseudomonas-aeruginosa-in-water-samples-in-central-italy-and-molecular-characterization-of-oprd-in-imipenem-resistant-isolates
#1
Giuditta Fiorella Schiavano, Elisa Carloni, Francesca Andreoni, Silvia Magi, Maria Chironna, Giorgio Brandi, Giulia Amagliani
SCOPE: This study aimed to analyse the prevalence, antibiotic resistance and genetic relatedness of P. aeruginosa isolates obtained from potable and recreational water samples (n. 8,351) collected from different settings (swimming pools, n. 207; healthcare facilities, n 1,684; accommodation facilities, n. 1,518; municipal waterworks, n. 4,500; residential buildings, n. 235). Possible mechanisms underlying resistance to imipenem, with particular focus on those involving oprD-based uptake, were also explored...
2017: PloS One
https://www.readbyqxmd.com/read/29210535/assessment-care-and-management-of-patients-with-red-eye
#2
Susan Watkinson, Ramesh Seewoodhary
Red eye is a common ocular presentation in primary care, and there are several challenges that healthcare practitioners may encounter when caring for such patients. The main ocular conditions that can give rise to red eye are: primary acute angle closure glaucoma, acute iritis, dry eye, blepharitis and conjunctivitis. Red eye can be classified as sight-threatening or non-sight-threatening. Many patients presenting with painless red eye and normal vision usually recover well. However, when red eye is associated with pain, photophobia, watering and blurred vision, it is potentially sight-threatening and must be addressed urgently...
December 6, 2017: Nursing Standard
https://www.readbyqxmd.com/read/29202396/does-coffee-affect-the-bowel-function-after-caesarean-section
#3
REVIEW
Soheila Rabiepoor, Atefeh Yas, Jamile Navaei, Hamid Reza Khalkhali
OBJECTIVES: Postoperative ileus is a common consequence of abdominal surgery, which tends to prolong the duration of hospital stay and imposes considerable economic costs on healthcare system. Coffee is proved to have positive effects on gastrointestinal motility index in healthy young adults. Thus, the present study aims to examine effects of coffee on bowel function after caesarean section. MATERIAL AND METHOD: A total number 100 patients after elective caesarean section were randomly assigned before surgery into control and intervention groups...
August 4, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29185013/assessment-of-arterially-hyper-enhancing-liver-lesions-using-virtual-monoenergetic-images-from-spectral-detector-ct-phantom-and-patient-experience
#4
N Große Hokamp, A J Höink, J Doerner, D W Jordan, G Pahn, T Persigehl, D Maintz, S Haneder
PURPOSE: To investigate a benefit from virtual monoenergetic reconstructions (VMIs) for assessment of arterially hyper-enhancing liver lesions in phantom and patients and to compare hybrid-iterative and spectral image reconstructions of conventional images (CI-IR and CI-SR). METHODS: All imaging was performed on a SDCT (Philips Healthcare, Best, The Netherlands). Images of a non-anthropomorphic phantom with a lesion-mimicking insert (containing iodine in water solution) and arterial-phase images from contrast-enhanced patient examinations were evaluated...
November 28, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29177099/estimating-the-need-for-inpatient-neonatal-services-an-iterative-approach-employing-evidence-and-expert-consensus-to-guide-local-policy-in-kenya
#5
REVIEW
Georgina A V Murphy, Donald Waters, Paul O Ouma, David Gathara, Sasha Shepperd, Robert W Snow, Mike English
Universal access to quality newborn health services will be essential to meeting specific Sustainable Development Goals to reduce neonatal and overall child mortality. Data for decision making are crucial for planning services and monitoring progress in these endeavours. However, gaps in local population-level and facility-based data hinder estimation of health service requirements for effective planning in many low-income and middle-income settings. We worked with local policy makers and experts in Nairobi City County, an area with a population of four million and the highest neonatal mortality rate amongst counties in Kenya, to address this gap, and developed a systematic approach to use available data to support policy and planning...
2017: BMJ Global Health
https://www.readbyqxmd.com/read/29176716/a-rapidly-reversible-absorptive-and-emissive-vapochromic-pt-ii-pincer-based-chemical-sensor
#6
M J Bryant, J M Skelton, L E Hatcher, C Stubbs, E Madrid, A R Pallipurath, L H Thomas, C H Woodall, J Christensen, S Fuertes, T P Robinson, C M Beavers, S J Teat, M R Warren, F Pradaux-Caggiano, A Walsh, F Marken, D R Carbery, S C Parker, N B McKeown, R Malpass-Evans, M Carta, P R Raithby
Selective, robust and cost-effective chemical sensors for detecting small volatile-organic compounds (VOCs) have widespread applications in industry, healthcare and environmental monitoring. Here we design a Pt(II) pincer-type material with selective absorptive and emissive responses to methanol and water. The yellow anhydrous form converts reversibly on a subsecond timescale to a red hydrate in the presence of parts-per-thousand levels of atmospheric water vapour. Exposure to methanol induces a similarly-rapid and reversible colour change to a blue methanol solvate...
November 27, 2017: Nature Communications
https://www.readbyqxmd.com/read/29175077/detection-limit-of-mycobacterium-chimaera-in-water-samples-for-monitoring-medical-device-safety-insights-from-a-pilot-experimental-series
#7
Peter W Schreiber, Nora Köhler, Rosita Cervera, Barbara Hasse, Hugo Sax, Peter M Keller
OBJECTIVE: A growing number of Mycobacterium chimaera infections after cardiosurgery have been reported by several countries. These often fatal infections were traced back to contaminated heater-cooler devices (HCDs), which use water as heat transfer medium. Aerosolization of water contaminated with M. chimaera from HCDs enables airborne transmission to patients undergoing open chest surgery. Infection control teams test HCD water samples for mycobacterial growth to guide preventive measures...
November 21, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29173230/water-cultures-are-more-sensitive-than-swab-cultures-for-the-detection-of-environmental-legionella
#8
Brooke K Decker, Patricia L Harris, Diana L Toy, Robert R Muder, Ali F Sonel, Cornelius J Clancy
Water cultures were significantly more sensitive than concurrently collected swab cultures (n=2,147 each) in detecting Legionella pneumophila within a Veterans Affairs healthcare system. Sensitivity for water versus swab cultures was 90% versus 30% overall, 83% versus 48% during a nosocomial Legionnaires' disease outbreak, and 93% versus 22% post outbreak. Infect Control Hosp Epidemiol 2017;1-3.
November 27, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29170113/anti-adherent-biomaterials-for-prevention-of-catheter-biofouling
#9
Colin P McCoy, Nicola J Irwin, Louise Donnelly, David S Jones, John G Hardy, Louise Carson
Medical device-associated infections present a leading global healthcare challenge, and effective strategies to prevent infections are urgently required. Herein, we present an innovative anti-adherent hydrogel copolymer as a candidate catheter coating with complementary hydrophobic drug-carrying and eluting capacities. The amphiphilic block copolymer, Poloxamer 188, was chemically-derivatized with methacryloyl moieties and copolymerized with the hydrogel monomer, 2-hydroxyethyl methacrylate. Performance of the synthesized copolymers was evaluated in terms of equilibrium swelling, surface water wettability, mechanical integrity, resistance to encrustation and bacterial adherence, and ability to control release of the loaded fluoroquinolone antibiotic, ofloxacin...
November 20, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29155825/poverty-and-health-among-cdc-plantation-labourers-in-cameroon-perceptions-challenges-and-coping-strategies
#10
Valerie Makoge, Lenneke Vaandrager, Harro Maat, Maria Koelen
Creating better access to good quality healthcare for the poor is a major challenge to development. In this study, we examined inter-linkages between poverty and disease, referred to as poverty-related diseases (PRDs), by investigating how Cameroon Development Corporation (CDC) camp dwellers respond to diseases that adversely affect their health and wellbeing. Living in plantation camps is associated with poverty, overcrowding, poor sanitation and the rapid spread of diseases. In a survey of 237 CDC camp dwellers in Cameroon, we used the health belief model to understand the drivers (perceived threats, benefits and cues for treatment seeking) of reported responses...
November 20, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29154847/behavioural-informatics-for-improving-water-hygiene-practice-based-on-iot-environment
#11
Yang Fu, Wenyan Wu
The development of Internet of Things (IoT) and latest Information and Communication Technologies (ICT) have changed the nature of healthcare monitoring and health behaviour intervention in many applications. Water hygiene and water conservation behaviour intervention as important influence factors to human health are gaining much attentions for improving sustained sanitation practice. Based on face-to-face delivery, typical behaviour intervention method is costly and hardly to provide all day access to personalised intervention guidance and feedbacks...
November 14, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/29148566/factors-that-influence-the-provision-of-intrapartum-and-postnatal-care-by-skilled-birth-attendants-in-low-and-middle-income-countries-a-qualitative-evidence-synthesis
#12
REVIEW
Susan Munabi-Babigumira, Claire Glenton, Simon Lewin, Atle Fretheim, Harriet Nabudere
BACKGROUND: In many low- and middle-income countries women are encouraged to give birth in clinics and hospitals so that they can receive care from skilled birth attendants. A skilled birth attendant (SBA) is a health worker such as a midwife, doctor, or nurse who is trained to manage normal pregnancy and childbirth. (S)he is also trained to identify, manage, and refer any health problems that arise for mother and baby. The skills, attitudes and behaviour of SBAs, and the extent to which they work in an enabling working environment, impact on the quality of care provided...
November 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29148024/blue-planet-dialysis-novel-water-sparing-strategies-for-reducing-dialysate-flow
#13
Alejandra Molano-Triviño, Benjamin Wancjer, Mauro M Neri, Akash N Karopadi, Mitchell Rosner, Claudio Ronco
INTRODUCTION: Hemodialysis (HD) is an expensive therapy in economic and in ecological terms, owing to a high carbon footprint and significant consumption of natural sources, especially water. Our aim was to review strategies to diminish waste of water in maintenance dialysis, exploring previously described water reuse trends and less known strategies for reducing the dialysate flow. METHODS: We conducted a systematic review of water-sparing strategies, including the reuse of reverse osmosis rejected water and the reduction of dialysate flux...
November 8, 2017: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/29143758/determination-of-the-bridging-ligand-in-the-active-site-of-tyrosinase
#14
Congming Zou, Wei Huang, Gaokun Zhao, Xiao Wan, Xiaodong Hu, Yan Jin, Junying Li, Junjun Liu
Tyrosinase is a type-3 copper enzyme that is widely distributed in plants, fungi, insects, and mammals. Developing high potent inhibitors against tyrosinase is of great interest in diverse fields including tobacco curing, food processing, bio-insecticides development, cosmetic development, and human healthcare-related research. In the crystal structure of Agaricus bisporus mushroom tyrosinase, there is an oxygen atom bridging the two copper ions in the active site. It is unclear whether the identity of this bridging oxygen is a water molecule or a hydroxide anion...
October 28, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29143623/the-impact-of-eliminating-within-country-inequality-in-health-coverage-on-maternal-and-child-mortality-a-lives-saved-tool-analysis
#15
Adrienne Clermont
BACKGROUND: Inequality in healthcare across population groups in low-income countries is a growing topic of interest in global health. The Lives Saved Tool (LiST), which uses health intervention coverage to model maternal, neonatal, and child health outcomes such as mortality rates, can be used to analyze the impact of within-country inequality. METHODS: Data from nationally representative household surveys (98 surveys conducted between 1998 and 2014), disaggregated by wealth quintile, were used to create a LiST analysis that models the impact of scaling up health intervention coverage for the entire country from the national average to the rate of the top wealth quintile (richest 20% of the population)...
November 7, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29126571/potential-applications-of-the-escherichia-coli-heat-shock-response-in-synthetic-biology
#16
REVIEW
Joana L Rodrigues, Lígia R Rodrigues
The Escherichia coli heat shock response (HSR) is a complex mechanism triggered by heat shock and by a variety of other growth-impairing stresses. We explore here the potential use of the E. coli HSR mechanism in synthetic biology approaches. Several components of the regulatory mechanism (such as heat shock promoters, proteins, and RNA thermosensors) can be extremely valuable in the creation of a toolbox of well-characterized biological parts to construct biosensors or microbial cell factories with applications in the environment, industry, or healthcare...
November 7, 2017: Trends in Biotechnology
https://www.readbyqxmd.com/read/29124876/trehalose-a-temperature-and-salt-induced-solute-with-implications-in-pathobiology-of-acinetobacter-baumannii
#17
Sabine Zeidler, Josephine Hubloher, Kim Schabacker, Pedro Lamosa, Helena Santos, Volker Müller
Acinetobacter baumannii is an opportunistic human pathogen that has become a global threat to healthcare institutions worldwide. A major factor contributing to success of this bacterium is its outstanding ability to survive on dry surfaces. The molecular basis for desiccation resistance is not completely understood. This study focused on growth under osmotic stress and aimed to identify the pool of compatible solutes synthesized in response to these low water activity conditions. A. baumannii produced mannitol as compatible solute, but in contrast to Acinetobacter baylyi, also trehalose was accumulated in response to increasing NaCl concentrations...
November 10, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/29120013/primary-polydipsia-in-the-medical-and-psychiatric-patient-characteristics-complications-and-therapy
#18
Clara Sailer, Bettina Winzeler, Mirjam Christ-Crain
Primary polydipsia (PP) has been defined as excessive intake of fluids. However, the pathogenesis of PP remains unexplored. Different theories include a dysfunction in the thirst mechanism, involvement of the hippocampus, stress-reducing behaviour and lesion occurrences in specific areas of the brain. Most studies have been performed in the psychiatric setting, indicating that PP coincides with schizophrenia, anxiety disorder and depression. However, an increasing number of case reports emphasise the incidence of PP in non-psychiatric patients...
November 9, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29119779/strategic-formulation-of-graphene-oxide-sheets-for-flexible-monoliths-and-robust-polymeric-coatings-that-embedded-with-durable-bio-inspired-wettability
#19
Avijit Das, Jumi Deka, Adil Majeed Rather, Bibhas K Bhunia, Partha Pratim Saikia, Biman B Mandal, Kalyan Raidongia, Uttam Manna
Artificial bio-inspired superhydrophobicity-that are generally developed through appropriate optimization of chemistry and hierarchical topography, is being recognized for its immense prospective applications related to environment and healthcare. Nevertheless, the week interfacial interaction that are associated in the fabrication of such special interfaces-makes the material often delicate, and embedded antifouling property collapses on exposures to harsh and complex aqueous phases, and also after regular physical deformations including bending, creasing etc...
November 9, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29113436/silver-calcium-and-copper-molybdate-compounds-preparation-antibacterial-activity-and-mechanisms
#20
Dajana Tanasic, Adriana Rathner, Jan Philipp Kollender, Petr Rathner, Norbert Müller, Karl Christian Zelenka, Achim Walter Hassel, Cezarina Cela Mardare
Developing novel compounds with antimicrobial properties can be an effective approach to decreasing the number of healthcare-associated infections, particularly in the context of medical devices and touch surfaces. A variety of molybdate powders (Ag2MoO4, CaMoO4, CuMoO4 and Cu3Mo2O9) were synthesized and characterized, and Escherichia coli was used as a model gram-negative bacterium to demonstrate their antimicrobial properties. Optical density measurements, bacterial colony growth, and stained gel images for protein expression clearly showed that silver- and copper molybdates inhibit bacterial growth, whereas CaMoO4 exhibited no bactericidal effect...
November 7, 2017: Biointerphases
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