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https://www.readbyqxmd.com/read/29778014/expression-of-grape-acs1-in-tomato-decreases-ethylene-and-alters-the-balance-between-auxin-and-ethylene-during-shoot-and-root-formation
#1
Xia Ye, Mengmeng Fu, Yu Liu, Dongliang An, Xianbo Zheng, Bin Tan, Jidong Li, Jun Cheng, Wei Wang, Jiancan Feng
Ethylene plays an important role in the grape rachis, where its production can be 10 times higher than in the berry. VvACS1 is the only rachis-specific ACC synthase (ACS) gene, and its expression is coincident with ethylene production in the rachis of Vitis vinifera 'Thompson seedless'. VvACS1 was cloned and ectopically expressed in tomato (Solanum lycopersicum 'Moneymaker'). Lateral buds were increased in two- or four-week-old 35s∷VvACS1 transgenic tomato plants after transplanting. Compared with wild-type (WT) plants, the transgenic tomato plants showed higher expression of the VvACS1 gene in the flowers, leaves, rachis, and fruits...
May 4, 2018: Journal of Plant Physiology
https://www.readbyqxmd.com/read/29776706/gaps-in-pain-agitation-and-delirium-management-in-intensive-care-outputs-from-a-nurse-workshop
#2
REVIEW
Carsten Hermes, Maria Acevedo-Nuevo, Andrea Berry, Thomas Kjellgren, Alessandra Negro, Paola Massarotto
Significant improvements in our understanding of pain, agitation, and delirium management within the Intensive Care Unit have been made in recent years. International guidelines and implementation bundles have become more evidence-based, patient-centred, and provide clear recommendations on the best-practice management of critically ill patients. However, the intensive care community has highlighted the need for higher-order evidence in several areas of pain, agitation and delirium research and studies suggest that a significant number of intensive care patients still receive outdated treatment as a consequence of inadequate guideline implementation...
May 15, 2018: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/29775790/clinical-course-of-nodular-regenerative-hyperplasia-in-thiopurine-treated-inflammatory-bowel-disease-patients
#3
Melek Simsek, Berrie Meijer, Dewkoemar Ramsoekh, Gerd Bouma, Egbert-Jan van der Wouden, Bert den Hartog, Annemarie C de Vries, Frank Hoentjen, Gerard Dijkstra, Sybrand Y de Boer, Jeroen M Jansen, Andrea E van der Meulen, Ruud Beukers, Menno A Brink, Toos Steinhauser, Bas Oldenburg, Lennard P Gilissen, Ton H Naber, Marc A Verhagen, Nanne K H de Boer, Chris J J Mulder
No abstract text is available yet for this article.
May 15, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29775677/managing-type-2-diabetes-as-a-couple-the-influence-of-partners-beliefs-on-diabetes-distress-over-time
#4
Berry Emma, Davies Mark, Dempster Martin
AIMS: Partners and spouses have an important role in supporting healthy self-care in adults with Type 2 diabetes. While evidence has shown that the beliefs held by people with diabetes influence emotional wellbeing, little is known about the long-term impact of partners' illness beliefs on diabetes distress. METHODS: Persons with Type 2 diabetes (pwt2d) and their partners completed a questionnaire at baseline (N=75 couples) and 12 months later (N=45 couples). Measures included demographic/ clinical parameters, the Revised Illness Perception questionnaire, and the Diabetes Distress Scale...
May 15, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29775359/model-prediction-of-self-rotating-excitons-in-two-dimensional-transition-metal-dichalcogenides
#5
Maxim Trushin, Mark Oliver Goerbig, Wolfgang Belzig
Using the quasiclassical concept of Berry curvature we demonstrate that a Dirac exciton-a pair of Dirac quasiparticles bound by Coulomb interactions-inevitably possesses an intrinsic angular momentum making the exciton effectively self-rotating. The model is applied to excitons in two-dimensional transition metal dichalcogenides, in which the charge carriers are known to be described by a Dirac-like Hamiltonian. We show that the topological self-rotation strongly modifies the exciton spectrum and, as a consequence, resolves the puzzle of the overestimated two-dimensional polarizability employed to fit earlier spectroscopic measurements...
May 4, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29775294/management-zone-delineation-for-winegrape-selective-harvesting-based-on-fluorescence-sensor-mapping-of-grape-skin-anthocyanins
#6
Giovanni Agati, Kamel Soudani, Lorenza Tuccio, Elisa Fierini, Naima Ben Ghozlen, El Mostafa Fadaili, Annalisa Romani, Zoran G Cerovic
We analyzed the potential of non-destructive optical sensing of grape skin anthocyanins for selective harvesting in precision viticulture. We measured anthocyanins by a hand-held fluorescence optical sensor on a 7-ha Sangiovese vineyard plot in central Italy. Optical indices obtained by the sensor were calibrated for the transformation in units of anthocyanins per berry mass, i.e. mg g-1 berry fresh weight. A full protocol for optimal data filtration, interpolation and homogenous zones delineation based on a very large number of optical measurements was proposed...
May 18, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29774911/pressure-induced-strong-ferroelectric-polarization-in-tetra-phase-perovskite-cspbbr-3
#7
Yu-Qing Zhao, Qi-Rui Ma, Biao Liu, Zhuo-Liang Yu, Meng-Qiu Cai
Ab initio simulations combined with the Berry phase method are employed to investigate ferroelectric polarization of tetragonal CsPbBr3 crystals by applying hydrostatic pressure varying from 0 to 19 GPa; we find that the object research belongs to the P4mm space group. The calculated results show that the materials undergo a paraelectric-ferroelectric phase transition when the pressure increases to a critical value 15 GPa. The polarization is strongly enhanced and attains a high value of about 23 μC cm-2, owing to the increase in the ionic and electric contributions to the polarization under compressive strain...
May 18, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29774337/fermentation-alters-the-bioaccessible-phenolic-compounds-and-increases-the-alpha-glucosidase-inhibitory-effects-of-aronia-juice-in-a-dairy-matrix-following-in-vitro-digestion
#8
Xue Du, Angela D Myracle
The prevalence of diabetes reached 415 million worldwide in 2015. Polyphenol-rich food intake can benefit the glycemic control for individuals with diabetes. Fermentation may increase the bioavailability of polyphenols, which is generally low. Aronia (Aronia melanocarpa) is a polyphenol-rich berry that is native to North America. Proanthocyanins and anthocyanins are the major phenolic compounds in aronia. In this study, aronia kefir was made by fermenting cow's milk with added aronia juice. The changes in bioaccessible polyphenols of aronia kefir during digestion were assessed using an in vitro model...
May 18, 2018: Food & Function
https://www.readbyqxmd.com/read/29772956/lumbar-muscle-structure-predicts-operational-postures-in-active-duty-marines
#9
David B Berry, Bahar Shahidi, Ana E Rodríguez-Soto, Jan M Hughes-Austin, Karen R Kelly, Samuel R Ward
Study Design Cross-sectional. Background The relationship between lumbar spine posture and muscle structure is not well understood. Objectives Investigate the predictive capacity of muscle structure on lumbar spine posture in active duty Marines. Methods Fouty-three Marines were scanned using an upright magnetic resonance imaging (MRI) scanner while standing unloaded and standing, sitting, and prone on elbows with body armor. Cobb, horizontal, and sacral angles were measured. Marines were then scanned unloaded in supine using a supine MRI scanner...
May 17, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29770777/shubnikov-de-haas-oscillations-in-i-p-i-and-i-n-i-type-topological-insulator-bi-sub-x-sub-sb-sub-1-x-sub-sub-2-sub-te-sub-3-sub
#10
Ryota Akiyama, Kazuki Sumida, Satoru Ichinokura, Ryosuke Nakanishi, Akio Kimura, Konstantin A Kokh, Oleg Tereshchenko, Shuji Hasegawa
We show Shubnikov-de Haas (SdH) oscillations in topological insulator (Bi<sub>x</sub>Sb<sub>1-x</sub>)<sub>2</sub>Te<sub>3</sub> flakes whose carrier types are <i>p</i>-type (<i>x</i> = 0.29, 0.34) and <i>n</i>-type (<i>x</i> = 0.42). The physical properties such as the Berry phase, carrier mobility, and scattering time significantly changed by tuning the Fermi-level position with the concentration <i>x</i>...
May 17, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/29770760/adherence-to-the-new-nordic-diet-during-pregnancy-and-subsequent-maternal-weight-development-a-study-conducted-in-the-norwegian-mother-and-child-cohort-study-moba
#11
Marianne Skreden, Elisabet R Hillesund, Andrew K Wills, Anne Lise Brantsæter, Elling Bere, Nina C Øverby
The rising prevalence of overweight and obesity is a worldwide public health challenge. Pregnancy and beyond is a potentially important window for future weight gain in women. We investigated associations between maternal adherence to the New Nordic diet (NND) during pregnancy and maternal BMI trajectories from delivery to 8 years post delivery. Data are from the Norwegian Mother and Child Cohort. Pregnant women from all of Norway were recruited between 1999 and 2008, and 55 056 are included in the present analysis...
June 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29770756/the-influence-of-juicing-on-the-appearance-of-blueberry-metabolites-2-h-after-consumption-a-metabolite-profiling-approach
#12
Swen Langer, Aileen Kennel, John K Lodge
The consumption of berries has been linked to decreased risk of degenerative disease. Berries are regularly processed into juices. It is largely unknown how the juicing process affects the bioavailability of metabolites. As metabolomics has shown to be a valuable nutritional tool to study global metabolite differences, the aim of this study was to investigate the effect of juicing on the relative appearance of blueberry metabolites in humans using metabolomics. Nine healthy subjects consumed 250 g of fresh blueberries either as the whole fruit or after juicing, and provided blood and urine samples before and 2 h after intake in a cross-over design...
June 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29770126/crosstalk-between-the-unfolded-protein-response-micrornas-and-insulin-signaling-pathways-in-search-of-biomarkers-for-the-diagnosis-and-treatment-of-type-2-diabetes
#13
REVIEW
Chinar Berry, Megha Lal, B K Binukumar
Type 2 diabetes mellitus (T2DM) is a metabolic disorder that is characterized by functional defects in glucose metabolism and insulin secretion. Its complex etiology and multifaceted nature have made it difficult to design effective therapies for early diagnosis and treatment. Several lines of evidence indicate that aberrant activation of the unfolded protein response (UPR) in response to endoplasmic reticulum (ER) stress impairs the β cell's ability to respond to glucose and promotes apoptosis. Elucidating the molecular mechanisms that govern β cell dysfunction and cell death can help investigators design therapies to halt or prevent the development of T2DM...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29767673/modeling-the-impact-of-folic-acid-fortification-and-supplementation-on-red-blood-cell-folate-concentrations-and-predicted-neural-tube-defect-risk-in-the-united-states-have-we-reached-optimal-prevention
#14
Krista S Crider, Yan Ping Qi, Owen Devine, Sarah C Tinker, Robert J Berry
Background: The US CDC and the Institute of Medicine recommend that women capable of becoming pregnant consume ≥400 µg synthetic folic acid/d to prevent neural tube defects (NTDs). The United States has 3 sources of folic acid: fortified enriched cereal grain products (ECGPs), fortified ready-to-eat (RTE) cereals, and dietary supplements. Objective: Our objectives were as follows: 1) to estimate the usual daily folic acid intake and distributions of red blood cell (RBC) folate concentrations among women consuming folic acid from different sources; 2) to assess the usual daily total folic acid intake associated with optimal RBC folate concentrations for NTD prevention; 3) to predict NTD prevalence; and 4) to estimate the number of preventable folate-sensitive NTDs...
May 14, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29765547/signature-program-a-platform-of-basket-trials
#15
Eric D Slosberg, Barinder P Kang, Julio Peguero, Matthew Taylor, Todd M Bauer, Donald A Berry, Fadi Braiteh, Alexander Spira, Funda Meric-Bernstam, Steven Stein, Sarina A Piha-Paul, August Salvado
Investigating targeted therapies can be challenging due to diverse tumor mutations and slow patient accrual for clinical studies. The Signature Program is a series of 8 phase 2, agent-specific basket protocols using a rapid study start-up approach involving no predetermined study sites. Each protocol evaluated 1 agent (buparlisib, dovitinib, binimetinib, encorafenib, sonidegib, BGJ398, ceritinib, or ribociclib) in patients with solid or hematologic malignancies and an actionable mutation. The primary endpoint of each study was the clinical benefit rate (ie, complete or partial response, or stable disease) at 16 weeks...
April 20, 2018: Oncotarget
https://www.readbyqxmd.com/read/29765379/-vitis-vinifera-l-fruit-diversity-to-breed-varieties-anticipating-climate-changes
#16
Antoine Bigard, Dargie T Berhe, Eleonora Maoddi, Yannick Sire, Jean-Michel Boursiquot, Hernan Ojeda, Jean-Pierre Péros, Agnès Doligez, Charles Romieu, Laurent Torregrosa
The wine industry is facing critical issues due to climate changes since production is established on very tight Genotype × Environment interaction bases. While, some cultivation practices may reduce adverse effects of abiotic stresses on the vines, e.g., the use of irrigation to mitigate drought, the deleterious impacts of warming on fruit development are difficult to manage. Elevated temperature alters grapevine fruit growth and composition, with a critical increase of the sugars/organic acids ratio. Select grapes with improved metabolite balances to offset high temperature effects is a valuable option to sustain viticulture...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29762653/recphyloxml-a-format-for-reconciled-gene-trees
#17
Wandrille Duchemin, Guillaume Gence, Anne-Muriel Arigon Chifolleau, Lars Arvestad, Mukul S Bansal, Vincent Berry, Bastien Boussau, François Chevenet, Nicolas Comte, Adrián A Davín, Christophe Dessimoz, David Dylus, Damir Hasic, Diego Mallo, Rémi Planel, David Posada, Celine Scornavacca, Gergely Szöllosi, Louxin Zhang, Éric Tannier, Vincent Daubin
Motivation: A reconciliation is an annotation of the nodes of a gene tree with evolutionary events-for example, speciation, gene duplication, transfer, loss, etc-along with a mapping onto a species tree. Many algorithms and software produce or use reconciliations but often using different reconciliation formats, regarding the type of events considered or whether the species tree is dated or not. This complicates the comparison and communication between different programs. Results: Here, we gather a consortium of software developers in gene tree species tree reconciliation to propose and endorse a format that aims to promote an integrative-albeit flexible-specification of phylogenetic reconciliations...
May 14, 2018: Bioinformatics
https://www.readbyqxmd.com/read/29761523/a-novel-cognitive-disease-progression-model-for-clinical-trials-in-autosomal-dominant-alzheimer-s-disease
#18
Guoqiao Wang, Scott Berry, Chengjie Xiong, Jason Hassenstab, Melanie Quintana, Eric M McDade, Paul Delmar, Matteo Vestrucci, Gopalan Sethuraman, Randall J Bateman
Clinical trial outcomes for Alzheimer's disease are typically analyzed by using the mixed model for repeated measures (MMRM) or similar models that compare an efficacy scale change from baseline between treatment arms with or without participants' disease stage as a covariate. The MMRM focuses on a single-point fixed follow-up duration regardless of the exposure for each participant. In contrast to these typical models, we have developed a novel semiparametric cognitive disease progression model (DPM) for autosomal dominant Alzheimer's disease based on the Dominantly Inherited Alzheimer Network (DIAN) observational study...
May 14, 2018: Statistics in Medicine
https://www.readbyqxmd.com/read/29761412/persistence-of-hepatitis-a-virus-in-fresh-produce-and-production-environments-and-the-effect-of-disinfection-procedures-a-review
#19
REVIEW
N Cook, I Bertrand, C Gantzer, R M Pinto, A Bosch
Although information is limited, it is evident that prolonged persistence of infectious Hepatitis A virus (HAV) is a factor in the transmission of the virus via fresh produce. Consequently, data on persistence of the virus on produce, and in environments relevant to production, such as soils, water and surfaces, are required to fully understand the dynamics of transmission of HAV via foods. Furthermore, information on effective disinfection procedures is necessary to implement effective post-harvest control measures...
May 14, 2018: Food and Environmental Virology
https://www.readbyqxmd.com/read/29757910/ishlt-primary-graft-dysfunction-incidence-risk-factors-and-outcome-a-uk-national-study
#20
Sanjeet Singh Avtaar Singh, Nicholas R Banner, Sally Rushton, Andre R Simon, Colin Berry, Nawwar Al-Attar
BACKGROUND: Heart transplantation (HTx) remains the most effective long-term treatment for advanced heart failure. Primary graft dysfunction (PGD) continues to be a potentially life-threatening early complication. In 2014, a consensus statement released by ISHLT established diagnostic criteria for PGD. We studied the incidence of PGD across the UK. METHODS: We analysed the medical records of all adult patients who underwent heart transplantation between October 2012-October 2015 in the 6 UK heart transplant centers Preoperative donor and recipient characteristics, intraoperative details and posttransplant complications were compared between the PGD and non PGD groups using the ISHLT definition...
May 1, 2018: Transplantation
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