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https://www.readbyqxmd.com/read/29326535/very-rare-presentation-of-cerebrovascular-accident-in-20-year-old-man-with-familial-mediterranean-fever-case-report
#1
Miramir Aghdashi, Seyed-Mostafa Seidmardani, Sara Vossoughian, Seyed Arman Seyed Mokhtari
Familial Mediterranean fever (FMF) is characterized by recurrent episodes of fever accompanied by serosal, synovial, or cutaneous inflammation. The central nervous system (CNS) is rarely involved in FMF. The CNS involvement includes demyelinating lesions, posterior reversible encephalopathy syndrome, pseudotumor cerebri, optic neuritis, and cerebral vasculitis. Here, we present a 20-year-old man, a known case of FMF with abrupt left-sided hemiparesis. Brain magnetic resonance imaging revealed right periventricular infarction...
2018: Clinical Medicine Insights. Case Reports
https://www.readbyqxmd.com/read/29326189/period-prevalence-risk-factors-and-consequent-injuries-of-falling-among-the-saudi-elderly-living-in-riyadh-saudi-arabia-a-cross-sectional-study
#2
Faisal Yousef Almegbel, Ibrahim Muthyib Alotaibi, Faisal Ahmed Alhusain, Emad M Masuadi, Salma Lafyan Al Sulami, Amairah Fahad Aloushan, Bashayer Ibrahim Almuqbil
OBJECTIVES: Approximately 28% to 35% of people aged 65 and over fall each year. The consequent injuries of falls are considered a major public health problem. Falls account for more than half of injury-related hospitalisations among old people. The aim of this study was to measure a 1-year period prevalence of falling among old people in Riyadh, Saudi Arabia. In addition, this study described the most common risk factors and consequent injuries of falls. SETTING AND PARTICIPANTS: A cross-sectional survey was carried out in Riyadh, using a convenient sampling...
January 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29324514/anticoagulant-bridge-comparison-in-mechanical-circulatory-support-patients
#3
Richard H Cosgrove, Robyn L Basken, Richard G Smith, Chiu-Hsieh Hsu, Toshinobu Kazui, Brandon K Martinez, Richard W Burt, Eric S Crawford, Scott D Lick, Zain Khalpey
Maintaining mechanical circulatory support (MCS) device patients in a specified therapeutic range for anticoagulation remains challenging. Subtherapeutic international normalized ratios (INRs) occur frequently while on warfarin therapy. An effective anticoagulant bridge strategy may improve the care of these patients. This retrospective review of MCS patients with subtherapeutic INRs compared an intravenous unfractionated heparin (UFH) strategy with a subcutaneous enoxaparin or fondaparinux strategy. Native thromboelastography (n-TEG) was used to evaluate anticoagulant effect with coagulation index (CI) as the primary outcome measure...
January 10, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29316169/elevated-blood-pressure-during-emergency-departments-visit-is-associated-with-increased-rate-of-hospitalization-for-heart-failure-a-retrospective-cohort-study
#4
Irit Ayalon-Dangur, Yaron Rudman, Tzippy Shochat, Shachaf Shiber, Alon Grossman
There is a limited literature discussing the long-term outcome of patients admitted to the emergency department with elevated blood pressure. The aim of the present study was to evaluate outcomes of patients with hypertension who attended an emergency department. All patients with hypertension who attended an emergency department without target organ damage were evaluated. A composite end point at 18 months, which included all-cause mortality, acute coronary syndrome, cerebrovascular accident, or hospitalization for heart failure, were compared between patients with hypertension and those with normotension...
January 5, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29305336/circulating-osteogentic-precursor-cells-in-non-hereditary-heterotopic-ossification
#5
REVIEW
Kevin P Egan, Gustavo Duque, Mary Ann Keenan, Robert J Pignolo
Non-hereditary heterotopic ossification (NHHO) may occur after musculoskeletal trauma, central nervous system (CNS) injury, or surgery. We previously described circulating osteogenic precursor (COP) cells as a bone marrow-derived type 1 collagen+CD45+subpopulation of mononuclear adherent cells that are able of producing extraskeletal ossification in a murine in vivo implantation assay. In the current study, we performed a tissue analysis of COP cells in NHHO secondary to defined conditions, including traumatic brain injury, spinal cord injury, cerebrovascular accident, trauma without neurologic injury, and joint arthroplasty...
January 2, 2018: Bone
https://www.readbyqxmd.com/read/29300429/dysphagia-in-hospitalized-older-patients-associated-factors-and-nutritional-interventions
#6
D Eglseer, R J G Halfens, J M G A Schols, C Lohrmann
OBJECTIVES: To (1) assess the association between dysphagia and malnutrition as well as other related factors and (2) investigate the nutritional interventions that are initiated in dysphagic older patients. DESIGN: Cross-sectional, multi-center point prevalence measurement. SETTING: 53 Austrian hospitals. PARTICIPANTS: 3174 hospitalized patients, 65 years or older. MEASUREMENTS: A standardized and tested questionnaire was used for the data collection, which was based on both inspections of the patients and information documented in the patient chart...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29296916/thromboembolic-event-rate-in-patients-exposed-to-anti-inhibitor-coagulant-complex-a-meta-analysis-of-40-year-published-data
#7
Matteo Rota, Paolo A Cortesi, Roberto Crea, Alessandro Gringeri, Lorenzo G Mantovani
Anti-inhibitor coagulant complex (AICC), an activated prothrombin complex concentrate, has been available for the treatment of patients with inhibitors since 1977, and thromboembolic events (TEEs) have been reported after infusion of AICC in patients with congenital or acquired hemophilia. With the aim of estimating the TEE incidence rate (IR) related to AICC exposure in these patients, a systematic review of the literature was carried out in Medline, according to PRISMA guidelines, from inception date to March 2017...
December 12, 2017: Blood Advances
https://www.readbyqxmd.com/read/29286954/selective-%C3%A3-1-blockers-are-not-associated-with-new-onset-diabetes-mellitus-in-hypertensive-patients
#8
Yoonjee Park, Byoung Geol Choi, Seung-Woon Rha, Man Jong Baek, Yang Gi Ryu, Se Yeon Choi, Jae Kyeong Byun, Min Suk Shim, Ahmed Mashaly, Hu Li, Won Young Jang, Woohyeun Kim, Jun Hyuk Kang, Jah Yeon Choi, Eun Jin Park, Sung Hun Park, Sunki Lee, Jin Oh Na, Cheol Ung Choi, Hong Euy Lim, Eung Ju Kim, Chang Gyu Park, Hong Seog Seo, Dong Joo Oh
BACKGROUND: Although ß-blockers are known to increase new-onset diabetes mellitus (DM), previous evidence have been controversial. It has been suggested that newer vasodilatory ß-blockers yield better glycemic control than older nonselective agents. The aim of this study was to evaluate the diabetogenicity of currently used newer ß-blockers based on ß1 receptor selectivity in a series of Asian population. METHODS: We investigated a total of 65,686 hypertensive patients without DM from 2004 to 2014...
January 2018: Journal of Cardiovascular Pharmacology
https://www.readbyqxmd.com/read/29286493/twenty-five-years-of-the-national-academy-of-medical-sciences-of-ukraine-progress-and-priorities-for-future-of-radiation-medicine-and-biology
#9
D Bazyka
After the creation of the Academy of Medical Sciences of Ukraine in 1993 the Research Center for Radiation Medicine was among the first institutions to join the Academy (fig. 1). Estab lishing the Academy was among the first steps of the independent Ukrainian government and aimed to provide a high level health care for population. It was extremely needed for the minimization of Chornobyl medical consequences. This choice was related to a growing recognition of the scientific research in fulfilling the Сenter's mission - study of the effects of low dose radiation on human body and radiation protection of the exposed population...
December 2017: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://www.readbyqxmd.com/read/29279045/ticagrelor-for-neuroendovascular-procedures-a-case-series
#10
Kyle Davis, Christopher Morrison
BACKGROUND: The development of thromboembolism is one of the most common complications of neuroendovascular procedures. Although several small studies have deemed clopidogrel safe and effective in the prevention of intracranial stent thrombosis, ticagrelor has yet to be assessed in this setting. OBJECTIVE: The objective of this study was to retrospectively evaluate the safety and efficacy of ticagrelor in patients undergoing neuroendovascular procedures. METHODS: A retrospective review of patients receiving ticagrelor following neuroendovascular aneurysm repair...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/29277532/levels-of-il-1%C3%AE-il-18-and-tnf-%C3%AE-in-cerebrospinal-fluid-of-aneurysmal-subarachnoid-hemorrhage-patients-may-be-predictors-of-early-brain-injury-and-clinical-prognosis
#11
Sheng-Yin Lv, Qi Wu, Jing-Peng Liu, Jiang Shao, Li-Li Wen, Jin Xue, Xiang-Sheng Zhang, Qing-Rong Zhang, Xin Zhang
BACKGROUND: Aneurysmal subarachnoid hemorrhage (aSAH) is a severe cerebrovascular accident with high morbidity and mortality. The aim of this study is to investigate the relationship between level of inflammatory cytokines in cerebrospinal fluid of aSAH patients, the severity of aSAH and the outcome of aSAH patients. METHODS: aSAH patients were prospectively included and followed-up 6 months. CSF samples were collected at 1-3 days, 4-6 days and 7-9 days after aSAH onset, respectively...
December 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29275371/stent-and-dual-antiplatelet-therapy-duration-comparisons-in-the-setting-of-a-multicenter-randomized-controlled-trial-can-the-operator-experience-affect-the-study-results
#12
Giuseppe Gargiulo, Dik Heg, Fabrizio Ferrari, Gianfranco Percoco, Gianluca Campo, Carlo Tumscitz, Federico Colombo, Andrea Zuffi, Fausto Castriota, Alberto Cremonesi, Stephan Windecker, Marco Valgimigli
BACKGROUND: Operator experience influences outcomes after percutaneous coronary intervention, but this association in the controlled setting of a randomized, clinical trial is unclear. METHODS AND RESULTS: We investigated operator-related outcomes (30-day and 2-year efficacy and safety end points) among patients undergoing percutaneous coronary intervention and randomized to different dual antiplatelet therapy durations and stent types. A total of 2003 patients were analyzed, and 7 operator groups were compared...
December 23, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29249687/male-incontinence-the-etiology-or-basis-of-treatment
#13
REVIEW
Austin G Hester, Alexander Kretschmer, Gopal Badlani
CONTEXT: Elderly men are an increasing proportion of the aging population in the 21st century. Urinary incontinence reduces the quality of life and increases the burden of care for the aging population. OBJECTIVE: The primary objective of this review is to explore the etiopathology of common causes of incontinence in aging male patients. The focus is on the algorithm of the initial evaluation of these patients from both a primary care and a urologic standpoint. EVIDENCE ACQUISITION: A nonsystematic review of the literature was performed in September 2017...
December 14, 2017: European Urology Focus
https://www.readbyqxmd.com/read/29249501/predictors-of-survival-in-octogenarians-after-mitral-valve-surgery-for-degenerative-disease-the-mitral-surgery-in-octogenarians-study
#14
Pierpaolo Chivasso, Vito D Bruno, Shakil Farid, Pietro Giorgio Malvindi, Amit Modi, Umberto Benedetto, Franco Ciulli, Yasir Abu-Omar, Massimo Caputo, Gianni D Angelini, Steve Livesey, Hunaid A Vohra
OBJECTIVES: An increasing number of octogenarians are referred to undergo mitral valve surgery for degenerative disease, and percutaneous approaches are being increasingly used in this subgroup of patients. We sought to determine the survival and its predictors after Mitral valve Surgery in Octogenarians (MiSO) in a multicenter UK study of high-volume specialized centers. METHODS: Pooled data from 3 centers were collected retrospectively. To identify the predictors of short-term composite outcome of 30 days mortality, acute kidney injury, and cerebrovascular accident, a multivariable logistic regression model was developed...
November 20, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29242494/incidental-anatomic-finding-of-celiacomesenteric-trunk-associated-with-nutcracker-phenomenon-or-compression-of-the-left-renal-vein
#15
Joshua Peterson, Anthony N Hage, Stephan Diljak, Benjamin D Long, Daniel P Marcusa, John M Stribley, David W Brzezinski, Jonathan Eliason
BACKGROUND Celiacomesenteric trunk (CMT) is a very rare anatomic finding in which the celiac artery and the superior mesenteric artery (SMA) originate from the abdominal aorta through a common trunk. Clinical associations with CMT include arterial aneurysm, thrombosis, and celiac artery compression. However, an association between CMT and abdominal venous congestion caused by left renal vein compression, or 'nutcracker phenomenon,' has not been previously reported. CASE REPORT A 91-year-old woman, who died from a cerebrovascular accident (CVA), underwent a cadaveric examination at our medical school...
December 15, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/29237015/perceval-less-invasive-aortic-replacement-register-multicentric-spanish-experience-with-the-perceval-s-bioprosthesis-in-moderate-high-risk-aortic-surgery
#16
Elisabet Berastegui García, Maria Luisa Camara Rosell, Francisco Estevez Cid, Eladio Sanchez Dominguez, Remedios Rios Barrera, Fabrizio Sbraga, Julio Garcia Puente, Elena Rosello Diez, Gregorio Pablo Cuerpo Caballero, Juan Bustamante Munguira, Guillermo Reyes Copa, Marian Tena Pajuelo, Santiago Serrano Fiz, Jose Alfonso Buendía Miñano, Ivan García Martin, Jose Cuenca Castillo, Sergio Cánovas Lopez, Angel Gonzalez Pinto, Xavier Ruyra Baliarda
OBJECTIVES: The development of new percutaneous and surgical techniques has reduced the risk associated with aortic valve replacement procedures. We present the results of a Spanish register after initiating a programme for sutureless prostheses in moderate-high-risk patients. METHODS: This prospective multicentre study was carried out from November 2013 to November 2016. Data were obtained from 448 patients in whom a Perceval S prosthesis was implanted. RESULTS: The mean age was 79...
December 8, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29235984/deaths-leading-causes-for-2015
#17
Melonie Heron
Objectives-This report presents final 2015 data on the 10 leading causes of death in the United States by age, sex, race, and Hispanic origin. Leading causes of infant, neonatal, and postneonatal death are also presented. This report supplements "Deaths: Final Data for 2015," the National Center for Health Statistics' annual report of final mortality statistics. Methods-Data in this report are based on information from all death certificates filed in the 50 states and the District of Columbia in 2015. Causes of death classified by the International Classification of Diseases, Tenth Revision (ICD-10) are ranked according to the number of deaths assigned to rankable causes...
November 2017: National Vital Statistics Reports
https://www.readbyqxmd.com/read/29226957/pilot-multi-centre-randomised-trial-of-the-impact-of-pre-operative-focused-cardiac-ultrasound-on-mortality-and-morbidity-in-patients-having-surgery-for-femoral-neck-fractures-echonof-2-pilot
#18
D J Canty, J Heiberg, Y Yang, A G Royse, S Margale, N Nanjappa, D Scott, A Maier, D I Sessler, A Chuan, A Palmer, A Bucknill, C French, C F Royse
Hip fracture surgery is common, usually occurs in elderly patients who have multiple comorbidities, and is associated with high morbidity and mortality. Pre-operative focused cardiac ultrasound can alter diagnosis and management, but its impact on outcome remains uncertain. This pilot study assessed feasibility and group separation for a proposed large randomised clinical trial of the impact of pre-operative focused cardiac ultrasound on patient outcome after hip fracture surgery. Adult patients requiring hip fracture surgery in four teaching hospitals in Australia were randomly allocated to receive focused cardiac ultrasound before surgery or not...
December 11, 2017: Anaesthesia
https://www.readbyqxmd.com/read/29225159/histopathology-of-periarticular-non-hereditary-heterotopic-ossification
#19
REVIEW
Kristin L Foley, Nader Hebela, Mary Ann Keenan, Robert J Pignolo
In the mature adult skeleton, new bone formation is normally restricted to regeneration of osseous tissue at sites of fracture. However, heterotopic ossification, or the formation of bone outside the normal skeleton, can occur within muscle, adipose, or fibrous connective tissue. Periarticular non-hereditary heterotopic ossification (NHHO) may occur after musculoskeletal trauma, following CNS injury, with certain arthropathies, or following injury or surgery that is often sustained in the context of age-related pathology...
December 7, 2017: Bone
https://www.readbyqxmd.com/read/29225000/-validity-of-the-abdominal-ecography-in-primary-care-for-detection-of-aorta-abdominal-aneurism-in-male-between-65-and-75-years
#20
Laura Bravo-Merino, Noelia González-Lozano, Ruth Maroto-Salmón, Gloria Meijide-Santos, Patricio Suárez-Gil, Ana Fañanás-Mastral
OBJECTIVE: To determine the usefulness of ultrasound examination in Primary Care (PC) for the detection of abdominal aortic aneurysm (AAA) in male patients from 65-75 years old, as well as the consistency between observers on the diagnosis between general practitioners and the reference specialty in this area, Vascular Surgery. To estimate the prevalence of AAA in that population and its association with risk factors. DESIGN: Cross-sectional descriptive study. LOCATION: Healthcare Centres of Coto and Calzada II (Gijón, Spain)...
December 7, 2017: Atencion Primaria
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