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Degenerative disc disease

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https://www.readbyqxmd.com/read/29783010/translaminar-approach-for-treatment-of-hidden-zone-foraminal-lumbar-disc-herniations-considerations-on-the-surgical-technique-and-pre-operative-selection-of-patients-with-a-long-term-follow-up
#1
Christian Cossandi, Andrea Fanti, Andrea Gerosa, Andrea Bianco, Riccardo Fornaro, Emanuela Crobeddu, Sara Forgnone, Gabriele Panzarasa, Andrea Di Cristofori
BACKGROUND: Lumbar disc herniation (LDH) is a common degenerative disease of the lumbar spine with a prevalence of 1-3% in population studies according to some authors. In 10% of patients there is a fragment migrated cranially in the Macnab's "hidden zone". In selected cases, this fragment can be removed with a translaminar approach that has been described in 1998. Aim of our work is to provide a detailed description of the technical advantages and pitfalls of such approach reviewing a consecutive series of patients...
May 18, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29777863/comparison-of-histological-and-morphometrical-changes-underlying-subchondral-bone-abnormalities-in-inflammatory-and-degenerative-musculoskeletal-disorders-a-systematic-review
#2
REVIEW
M Loef, S van Beest, F P B Kroon, J L Bloem, O M Dekkers, M Reijnierse, J W Schoones, M Kloppenburg
OBJECTIVE: Subchondral bone abnormalities (SBAs) on magnetic resonance imaging (MRI) are observed frequently and associated with disease course in various musculoskeletal disorders. This review aims to map the existing knowledge of their underlying histological features, and to identify needs for future research. DESIGN: We conducted a systematic review following PRISMA guidelines until September 2017, including all studies correlating histological features to on MRI defined SBAs in patients with osteoarthritis (OA), rheumatoid arthritis (RA), spondyloarthritis (SpA) and degenerative disc disease (DDD)...
May 16, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29777250/prevalence-of-temporomandibular-disorders-in-patients-with-hashimoto-thyroiditis
#3
Alina Grozdinska, Elisabeth Hofmann, Matthias Schmid, Ursula Hirschfelder
OBJECTIVES: Autoimmune thyroid disease (AITD), also known as Hashimoto thyroiditis (HT), is a degenerative inflammatory disease with high prevalence among women and has been associated with fibromyalgia and widespread chronic pain. The goal was to determine the frequency of temporomandibular disorders (TMD) in patients with HT. METHODS: In all, 119 women (age 19-60 years) were divided into a study (52 women diagnosed with HT) and a control (67 healthy individuals, of which 15 were excluded) group...
May 17, 2018: Journal of Orofacial Orthopedics, Fortschritte der Kieferorthopädie
https://www.readbyqxmd.com/read/29772868/-significance-of-cell-autophagy-in-resorption-of-lumbar-disc-herniation
#4
REVIEW
Zhi-Jun Diao, Hong Jiang, Jin-Tao Liu
As a self-protective mechanism of cells, autophagy of cells can maintain cell stability by degrading self-aging substances, and it can be highly induced. The ability of autophagy to degraded cells will decrease with age. The resorption phenomenon after lumbar disc herniation is one of the effective mechanisms in conservative treatment of lumbar disc herniation. The degenerative lesion of intervertebral disc is one of the main reasons of lumbar disc herniation. Cell autophagy is extensive participation in the degeneration of lumbar intervertebral disc, delaying the occurrence of degenerative disease...
April 25, 2018: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29770280/effect-of-body-mass-index-on-perioperative-outcomes-in-minimally-invasive-oblique-lateral-lumbar-interbody-fusion-versus-open-fusions-a-multivariant-analysis
#5
Hamid Abbasi, Alex Grant
Background Obesity is an increasing public health concern associated with increased perioperative complications and expense in lumbar spine fusions. While open and mini-open fusions such as transforaminal lumbar interbody fusion (TLIF) and minimally invasive TLIF (MIS-TLIF) are more challenging in obese patients, new MIS procedures like oblique lateral lumbar interbody fusion (OLLIF) may improve perioperative outcomes in obese patients relative to TLIF and MIS-TLIF. Purpose The purpose of this study is to determine the effects of obesity on perioperative outcomes in OLLIF, MIS-TLIF, and TLIF...
March 8, 2018: Curēus
https://www.readbyqxmd.com/read/29764039/-long-term-efficacy-of-cervical-artificial-disc-replacement-for-cervical-degenerative-diseases
#6
Q P Song, W Tian, D He, X Han, N Zhang, J C Wang, Z C Li
Objective: To evaluate the long-term efficacy of cervical artificial disc replacement for patients with cervical disc herniation and degenerative cervical canal stenosis. Methods: Total of sixty-eight patients underwent single-level Bryan artificial disc replacement in Beijing Jishuitan Hospital from December 2003 to December 2007 with a minimum 10-year follow-up were retrospectively analyzed. There were 43 males and 25 females with a mean age of (46±8) years. According to preoperative CT and MRI, the patients were divided into two groups: 27 patients in cervical disc herniation group and 41 patients in degenerative cervical canal stenosis group...
May 8, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29762112/lumbar-discography-is-associated-with-poor-return-to-work-status-following-lumbar-fusion-surgery-in-a-workers-compensation-setting
#7
Joshua T Anderson, Jeffrey A O'Donnell, Arnold R Haas, Rick Percy, Stephen T Woods, Uri M Ahn, Nicholas U Ahn
Lumbar discography (LD) is used to guide surgical decision making in patients with degenerative disc disease (DDD). Its safety and diagnostic accuracy are under contention. This study evaluates LD's efficacy within the workers' compensation (WC) population. Multivariate logistic regression analysis was used to determine the impact that undergoing LD before lumbar fusion for DDD had on return to work (RTW) rates among 1407 WC subjects. Discography was negatively associated with RTW status (p = .042; OR 0.76); 22...
2018: Journal of Surgical Orthopaedic Advances
https://www.readbyqxmd.com/read/29753275/cervical-spine-fracture-through-a-cervical-disc-replacement
#8
M Flanagan, D T Cawley, N Cassidy
INTRODUCTION: We report a rare case of cervical spine trauma through a cervical disc replacement and adjacent multilevel disc fusions. Cervical disc replacement (CDR) is a viable option for the surgical treatment of degenerative disc disease however long term follow up data regarding this operative technique is poor specifically relating to traumatic complications. We know of no previous reports of bilateral cervical pedicle fractures occurring adjacent to CDR and anterior cervical spine instrumentation...
March 29, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29751126/radiological-follow-up-after-implanting-cervical-disc-prosthesis-in-anterior-discectomy-a-systematic-review
#9
REVIEW
Xiaoyu Yang, Tessa Janssen, Mark P Arts, Wilco C Peul, Carmen L A Vleggeert-Lankamp
Objective The objective of this study was to review current literature on comparison of radiological outcome of cervical arthroplasty with fusion after anterior discectomy for radiculopathy. Methods A literature search was performed in PubMed, Embase, Web of Science, COCHRANE, CENTRAL and CINAHL using a sensitive search string combination. Studies were selected by predefined selection criteria (a.o. patients exclusively suffering from cervical radiculopathy) and risk of bias was assessed using a validated Cochrane Checklist adjusted for this purpose...
May 8, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29744650/a-novel-in-vivo-porcine-model-of-intervertebral-disc-degeneration-induced-by-cryoinjury
#10
Charles-Henri Flouzat-Lachaniette, Nicolas Jullien, Charlie Bouthors, Eric Beohou, Béatrice Laurent, Philippe Bierling, Arnaud Dubory, Hélène Rouard
PURPOSE: Degenerative disc disease involves sequential events that lead to the loss of cells, a decrease in disc matrix production, disc dehydration, and alteration of its biomechanical properties. The aim of this study was to determine whether cryoinjury of the nucleus pulposus performed through endplate perforation contributes to disc degeneration and to compare this technique with standard methods. METHOD: Under general anesthesia, the lumbar discs of six pigs were exposed and randomly submitted to needle puncture of the annulus fibrosus (NeP), isolated endplate injury (EP), or cryoinjury using a 2...
May 10, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29734947/association-between-fas-fasl-gene-polymorphism-and-musculoskeletal-degenerative-diseases-a-meta-analysis
#11
Donghua Huang, Jinrong Xiao, Xiangyu Deng, Kaige Ma, Hang Liang, Deyao Shi, Fashuai Wu, Zengwu Shao
BACKGROUND: It was reported that Fas (rs1800682, rs2234767) and FasL (rs5030772, rs763110) gene polymorphism might be related to the risk of musculoskeletal degenerative diseases (MSDD), such as osteoarthritis (OA), intervertebral disc degeneration (IVDD) and rheumatoid arthritis (RA). However, data from different studies was inconsistent. Here we aim to elaborately summarize and explore the association between the Fas (rs1800682, rs2234767) and FasL (rs5030772, rs763110) and MSDD. METHODS: Literatures were selected from PubMed, Web of Science, Embase, Scopus and Medline in English and VIP, SinoMed, Wanfang and the China National Knowledge Infrastructure (CNKI) in Chinese up to August 21, 2017...
May 7, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29734112/a-comparison-of-a-self-locking-stand-alone-cage-and-anterior-cervical-plate-for-acdf-minimum-3-year-assessment-of-radiographic-and-clinical-outcomes
#12
Jian Zhou, Juan Li, Hong Lin, Xilei Li, Xiaogang Zhou, Jian Dong
OBJECTIVES: The self-locking stand-alone cage has been clinically applied in treating cervical degenerative disc disease (CDDD). However, no long-term clinical and radiographic studies have been performed so far. This retrospective study was designed to analyze and compare the efficacy and outcomes of anterior cervical discectomy and fusion (ACDF) using self-locking stand-alone cages and cages with the anterior cervical plating system. PATIENTS AND METHODS: A total of 98 consecutive patients were recruited in this study...
April 30, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29732431/platelet-rich-plasma-injections-an-emerging-therapy-for-chronic-discogenic-low-back-pain
#13
REVIEW
Suja Mohammed, James Yu
Autologous platelet-rich plasma (PRP) injections have been investigated in recent years as an emerging therapy for various musculoskeletal conditions, including lumbar degenerative disc disease. Although PRP has received increasing attention from medical science experts, comprehensive clinical reports of its efficacy are limited to those treating knee osteoarthritis and epicondylitis. Use of PRP is gaining popularity in the area of degenerative disc disease, but there is a clear need for reliable clinical evidence of its applications and effectiveness...
March 2018: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29732419/complications-following-single-level-interbody-fusion-procedures-an-acs-nsqip-study
#14
Jamal N Shillingford, Joseph L Laratta, Joseph M Lombardi, John D Mueller, Meghan Cerpa, Hemant P Reddy, Comron Saifi, Charla R Fischer, Ronald A Lehman
Background: Controversy exists over the ability of various lumbar interbody fusion techniques to realign global and regional balance and their effect on patient outcomes. This is a retrospective cohort study to compare thirty-day postoperative outcomes between anterior and posterior interbody fusion techniques within a large national database. Methods: A retrospective cohort study utilizing the National Surgical Quality Improvement Program (NSQIP) database included 2,372 (29...
March 2018: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29730459/are-patient-reported-outcome-measures-biased-by-method-of-follow-up-evaluating-paper-based-and-digital-follow-up-after-lumbar-fusion-surgery
#15
Marc L Schröder, Marlies P de Wispelaere, Victor E Staartjes
BACKGROUND CONTEXT: Long-term follow-up of patient-reported outcome measures (PROM) is essential in both modern spinal care as well as in research. Lack of time and staff are commonly reported barriers to implementing long-term follow-up of PROM. Automated and digital follow-up systems for PROM collection are seeing widespread use, yet their validity and comparative effectiveness have never been evaluated. PURPOSE: To assess the validity of digital follow-up systems in comparison with the conventional paper-based follow-up...
May 3, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29723636/mechanical-loading-of-intervertebral-disc-modulates-microglia-proliferation-activation-and-chemotaxis
#16
Stefania Elena Navone, Marianna Peroglio, Laura Guarnaccia, Matteo Beretta, Sibylle Grad, Moira Paroni, Chiara Cordiglieri, Marco Locatelli, Mauro Pluderi, Paolo Rampini, Rolando Campanella, Mauro Alini, Giovanni Marfia
OBJECTIVE: The aim of the study is to assess the effects of the neuroinflammatory microenvironment of a mechanically-induced degenerating IVD on neuroinflammatory like cells such as microglia, in order to comprehend the role of microglial cells in degenerative disc disease. METHODS: Bovine caudal IVDs were kept in culture in an ex vivo bioreactor under high frequency loading and limited nutrition or in free swelling conditions as control samples. Conditioned media (CM) were collected, analysed for cytokine and neurotrophin content and applied to microglial cells for neuroinflammatory activation assessment...
April 30, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29718882/severe-hip-joint-motion-restriction-in-a-patient-with-diffuse-idiopathic-skeletal-hyperostosis-a-case-report
#17
Wonho Lee, Wook Ro Kim, Min Cheol Chang
RATIONALE: Severe limitation of motion (LOM) in the spine occasionally occurs in patients with diffuse idiopathic skeletal hyperostosis (DISH). However, in extraspinal areas, significant LOM has rarely been reported. In this study, we report a patient with DISH who had severe motion restriction within both hip joints. PATIENT CONCERNS: A 57-year-old man presented with a 10-year history of LOM of bilateral hip joints. He had gait difficulty due to shortened stride length induced by LOM...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29713407/the-incidence-of-adjacent-segment-degeneration-after-the-use-of-a-versatile-dynamic-hybrid-stabilization-device-in-lumbar-stenosis-results-of-a-5-8-year-follow-up
#18
Mauro Dobran, Davide Nasi, Domenico Paolo Esposito, Maurizio Gladi, Massimo Scerrati, Maurizio Iacoangeli
Study Design: Retrospective study with long-term follow-up. Purpose: To evaluate the long-term incidence of adjacent segment degeneration (ASD) and clinical outcomes in a consecutive series of patients who underwent spinal decompression associated with dynamic or hybrid stabilization with a Flex+TM stabilization system (SpineVision, Antony, France) for lumbar spinal stenosis. Overview of Literature: The incidence of ASD and clinical outcomes following dynamic or hybrid stabilization with the Flex+TM system used for lumbar spinal stenosis have not been well investigated...
April 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/29709550/is-the-behavior-of-disc-replacement-adjacent-to-fusion-affected-by-the-location-of-the-fused-level-in-hybrid-surgery
#19
Ting-Kui Wu, Yang Meng, Bei-Yu Wang, Ying Hong, Xin Rong, Chen Ding, Hua Chen, Hao Liu
BACKGROUND: Context: Hybrid surgery (HS), consisting of cervical disc arthroplasty (CDA) at the mobile level, along with anterior cervical discectomy and fusion (ACDF) at the spondylotic level, could be a promising treatment for patients with multilevel cervical degenerative disc disease (DDD). An advantage of this technique is that it utilizes an optimal procedure according to the status of each level. However, information is lacking regarding the influence of the relative location of the replacement and the fusion segment in vivo...
April 27, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29707555/lumbar-disc-reherniation-after-transforaminal-lumbar-endoscopic-discectomy
#20
Thomas A Kosztowski, David Choi, Jared Fridley, Michael Galgano, Ziya Gokaslan, Adetokunbo Oyelese, Albert Edward Telfeian
Background: Transforaminal lumbar endoscopic discectomy is a minimally invasive surgical procedure that can be performed in awake patients through an incision less than 1 cm. The procedure requires very little bony removal to access the herniated disc material because the approach is through the foramen, and only a small amount of the superior articulating process is removed to access Kambin's triangle. This study describes our experience with transforaminal endoscopic lumbar decompression (TELD) for the treatment of lumbar disc herniation...
March 2018: Annals of Translational Medicine
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