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Liberation medicine

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https://www.readbyqxmd.com/read/29729659/improving-health-care-for-critically-ill-patients-using-an-evidence-based-collaborative-approach-to-abcdef-bundle-dissemination-and-implementation
#1
Mary Ann Barnes-Daly, Brenda T Pun, Lori A Harmon, Diane G Byrum, Vishakha K Kumar, John W Devlin, Joanna L Stollings, Kathleen A Puntillo, Heidi J Engel, Patricia J Posa, Juliana Barr, William D Schweickert, Cheryl L Esbrook, Ken D Hargett, Shannon S Carson, J Matthew Aldrich, E Wesley Ely, Michele C Balas
BACKGROUND: Patients admitted to intensive care units (ICUs) often experience pain, oversedation, prolonged mechanical ventilation, delirium, and weakness. These conditions are important in that they often lead to protracted physical, neurocognitive, and mental health sequelae now termed postintensive care syndrome. Changing current ICU practice will not only require the adoption of evidence-based interventions but the development of effective and reliable teams to support these new practices...
May 5, 2018: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/29724984/a-study-on-the-korean-medicine-education-and-the-changes-in-the-traditional-korean-medicine-during-the-japanese-colonial-era-focused-on-the-korean-medicine-training-schools
#2
Yongyuan Huang
The modern education institutes play an important role in fostering professional talents, reproducing knowledge and studies, and forming the identities of certain academic fields and vocational communities. It is a matter of common knowledge that the absence of an official Korean medicine medical school during the Japanese colonial era was a severely disadvantageous factor in the aspects of academic progress, fostering follow-up personnel, and establishment of social capability. Therefore, the then Korean medicine circle put emphasis on inadequate official education institutes as the main factor behind oppression...
April 2018: Ŭi Sahak
https://www.readbyqxmd.com/read/29608648/conscientious-objection-in-medicine-accommodation-versus-professionalism-and-the-public-good
#3
Udo Schuklenk
Introduction: In recent years questions have arisen about the moral justification for the accommodation of health care professionals who refuse, on conscience grounds as opposed to professional grounds, to provide particular professional services to eligible patients who request that kind of service. Source of data: Literature review. Areas of disagreement: Central to concerns about the accommodation claims of conscientious objectors is that health care professionals volunteer to join their professions that typically they are the monopoly providers of such services and that a health care professional's refusal to provide professional services on grounds that are not professional judgements amounts to unprofessional conduct...
March 28, 2018: British Medical Bulletin
https://www.readbyqxmd.com/read/29605272/impact-of-ambiguous-and-restrictive-regulations-on-opioid-prescribing-practice-in-georgia
#4
Pati Dzotsenidze, Tamar Lekashvili, Nino Chikhladze, Maka Jorbenadze, Ioseb Abesadze, Dimitri Kordzaia
CONTEXT: Chronic pain management with opioids in incurable patients remains a challenge of modern medicine regardless of the evidence-based effectiveness of opioids and recommendations of authorities such as the World Health Organization and International Narcotics Control Board. Many countries, including Georgia, maintain overly restrictive regulations that contribute to inadequate pain management. OBJECTIVE: To identify barriers to pain management in Georgia caused by legislation, administrative issues, and physicians' lack of knowledge and understanding of legislative aspects governing opioid use, and their impact on opioid-prescribing practice...
March 29, 2018: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29574425/blood-transfusion-practice-in-the-uk-and-ireland-a-survey-of-palliative-care-physicians
#5
Karen Neoh, Simon Stanworth, Michael I Bennett
OBJECTIVES: Red cell (blood) transfusions are used in palliative care to manage patients with symptomatic anaemia or when patients have lost blood. We aimed to understand current blood transfusion practice among palliative medicine doctors and compare this with National Institute for Health and Care Excellence (NICE) guidance. NICE guidance advocates more restrictive transfusion practice but is based on clinical trials in non-palliative care contexts; the extent to which these findings should be applied to palliative care remains unclear...
March 23, 2018: BMJ Supportive & Palliative Care
https://www.readbyqxmd.com/read/29527054/historical-aspects-of-the-institute-of-psychiatry-and-human-behavior-goa
#6
Ashish Srivastava, Bramhanand Cuncoliencar, Yvonne Da Silva Pereira
Organized delivery of mental health services in Goa had its origin during the Portuguese regime. From the inception of a mental asylum in the 1500s, mental health services have come a long way. In post liberation period, after 1961, under the guidance of a WHO Consultant, Dr. Govindaswamy, a new mental hospital was built at Panaji, Goa and it was named as the Abbe de Faria Institute. The Department of Psychiatry in Goa Medical College was established in 1968, and unlike in most parts of the country, where Psychiatry was a part of Medicine; here in Goa, it enjoyed an independent departmental status...
February 2018: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/29522190/society-and-personal-genome-data
#7
Anna Middleton
Genomic data offer a goldmine of information for understanding the contribution of genetic variation makes to health and disease. The potential of genomic medicine, to predict, diagnose, manage and treat genetic disease, is underpinned by accurate variant interpretation. This in itself hinges on the ability to access large and varied genomic databases. There is now recognition that international collaboration between research and healthcare systems are paramount to delivering the scale of genomic data required...
May 1, 2018: Human Molecular Genetics
https://www.readbyqxmd.com/read/29513750/hemoglobin-transfusion-trigger-in-an-internal-medicine-department-a-real-world-six-year-experience
#8
Naomi Rahimi-Levene, Tomer Ziv-Baran, Victoria Peer, Ahuva Golik, Abraham Kornberg, Ronit Zeidenstein, Maya Koren-Michowitz
BACKGROUND: Transfusion guidelines advocate restrictive rather than liberal use of red blood cells (RBC) and are based mostly on randomized trials in intensive care and surgical departments. We aimed to study RBC transfusion practice in the medical patients' population. METHODS: The data in this study were collected from patients over the age of 18 years admitted to an Internal Medicine department between 2009 and 2014 who received at least one unit of packed red blood cells (RBC)...
2018: PloS One
https://www.readbyqxmd.com/read/29502527/expert-consensus-on-the-evaluation-and-diagnosis-of-combat-injuries-of-the-chinese-people-s-liberation-army
#9
Zhao-Wen Zong, Lian-Yang Zhang, Hao Qin, Si-Xu Chen, Lin Zhang, Lei Yang, Xiao-Xue Li, Quan-Wei Bao, Dao-Cheng Liu, Si-Hao He, Yue Shen, Rong Zhang, Yu-Feng Zhao, Xiao-Zheng Zhong
The accurate assessment and diagnosis of combat injuries are the basis for triage and treatment of combat casualties. A consensus on the assessment and diagnosis of combat injuries was made and discussed at the second annual meeting of the Professional Committee on Disaster Medicine of the Chinese People's Liberation Army (PLA). In this consensus agreement, the massive hemorrhage, airway, respiration, circulation and hypothermia (MARCH) algorithm, which is a simple triage and rapid treatment and field triage score, was recommended to assess combat casualties during the first-aid stage, whereas the abbreviated scoring method for combat casualty and the MARCH algorithm were recommended to assess combat casualties in level II facilities...
February 13, 2018: Military Medical Research
https://www.readbyqxmd.com/read/29420761/chinese-military-evaluation-of-a-portable-near-infrared-detector-of-traumatic-intracranial-hematomas
#10
Chun-Yang Liang, Yang Yang, Chun-Sen Shen, Hai-Jiang Wang, Nai-Ming Liu, Zhi-Wen Wang, Feng-Lei Zhu, Ru-Xiang Xu
Introduction: Secondary brain injury is the main cause of mortality from traumatic brain injury (TBI). One hallmark of TBI is intracranial hemorrhage, which occurs in 40-50% of severe TBI cases. Early identification of intracranial hematomas in TBI patients allows early surgical evacuation and can reduce the case fatality rate of TBI. As pre-hospital care is the weakest part of Chinese emergency care, there is an urgent need for a capability to detect brain hematomas early. In China, in addition to preventing injuries and diseases in military staff and in enhancing the military armed forces during war, military medicine participates in actions such as emergency public health crises, natural disasters, emerging conflicts, and anti-terrorist campaigns during peacetime...
February 6, 2018: Military Medicine
https://www.readbyqxmd.com/read/29341029/in-vitro-and-in-situ-absorption-and-metabolism-of-sesquiterpenes-from-petasites-hybridus-extracts
#11
Lucia Disch, Kristina Forsch, Beate Siewert, Jürgen Drewe, Gert Fricker
Petasites hybridus extract is used in the treatment of seasonal allergic rhinitis. The aim of this study was to evaluate the active constituent petasin and its isomers isopetasin and neopetasin (petasins) in the P. hybridus extract Ze 339 for liberation, dissolution, absorption, and metabolism. The determination of pH-dependent thermodynamic solubility was performed via the shake-flask method. Petasins exhibited a low solubility that was pH independent. In vivo, the concentration of solute drugs is decreased continuously by intestinal absorption...
January 16, 2018: Planta Medica
https://www.readbyqxmd.com/read/29311532/the-formation-of-the-military-medical-system-of-the-korean-people-s-army-and-the-military-medical-officer
#12
Seonho Kim
The military medical system of the Korean People's Army (KPA) first appeared in August 1946 when a central military hospita was established at the headquarters. Inside the KPA, the military medical and veteran services were first established in February 1948. The military medical officers of the KPA were those who were initially engaged in North Korea's health care sector. Most of the early military medical officers were those who had been trained in the Japanese medical system before liberation and were surgeons...
December 2017: Ŭi Sahak
https://www.readbyqxmd.com/read/29309173/-holy-trinity-monument-in-the-city-of-osijek
#13
Bruno Atalić
Plague was one of the most deadly epidemic diseases of the Baroque period. Responses to it were not only medical, but religious as well. A good example of the latter is the Most Holy Trinity monument in the city of Osijek, which was in the 18th century the biggest town of the Kingdom of Slavonia and today is the regional centre in the Republic of Croatia. The monument was erected between 1729 and 1730 on the main square of the Osijek military fortress Tvrđa by the widow of the General Maksimilijan Petraš who died during the 1728 plague epidemic...
December 2017: Acta Medico-historica Adriatica: AMHA
https://www.readbyqxmd.com/read/29298708/case-study-of-a-user-driven-prosthetic-arm-design-bionic-hand-versus-customized-body-powered-technology-in-a-highly-demanding-work-environment
#14
Wolf Schweitzer, Michael J Thali, David Egger
BACKGROUND: Prosthetic arm research predominantly focuses on "bionic" but not body-powered arms. However, any research orientation along user needs requires sufficiently precise workplace specifications and sufficiently hard testing. Forensic medicine is a demanding environment, also physically, also for non-disabled people, on several dimensions (e.g., distances, weights, size, temperature, time). METHODS: As unilateral below elbow amputee user, the first author is in a unique position to provide direct comparison of a "bionic" myoelectric iLimb Revolution (Touch Bionics) and a customized body-powered arm which contains a number of new developments initiated or developed by the user: (1) quick lock steel wrist unit; (2) cable mount modification; (3) cast shape modeled shoulder anchor; (4) suspension with a soft double layer liner (Ohio Willowwood) and tube gauze (Molnlycke) combination...
January 3, 2018: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/29278638/attitudes-of-students-of-medicine-university-of-mostar-according-to-induced-abortion
#15
Zoran Trninić, Marija Bender, Nikica Šutalo, Davorin Kozomara, Valentina Lasić, Danijel Bevanda, Gordan Galić
BACKGROUND: Aim of this study was to establish attitudes of medical students on induced abortion and connection of those attitudes with religiousness, length of their studies, sex and various circumstances of pregnancy. SUBJECTS AND METHODS: In total, 148 students of the first, second, fifth and sixth year of medical faculty participated in the research. The study was conducted at the Medical Faculty of the University in Mostar. While collecting the data, we used a survey taken over from literature...
December 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/29178797/unprotected-indazoles-are-resilient-to-ring-opening-isomerization-a-case-study-on-catalytic-c-s-couplings-in-the-presence-of-strong-base
#16
Jacob M Ganley, Charles S Yeung
Indazoles represent a privileged scaffold in medicinal chemistry. In the presence of strong base, however, N-protected indazoles are prone to an undesirable ring-opening reaction to liberate o-aminobenzonitriles. By employing unprotected indazoles with a free N-H bond, isomerization is averted because the heterocycle is deprotonated in situ. We herein report functional group-tolerant and robust C-S couplings of bromoindazoles with thiols of varying electronic nature in the presence of lithium bis(trimethylsilyl)amide at elevated temperatures...
December 15, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29171151/live-cell-microrna-imaging-through-mno-2-nanosheet-mediated-dd-a-hybridization-chain-reaction
#17
Min Ou, Jin Huang, Xiaohai Yang, Xiaoxiao He, Ke Quan, Yanjing Yang, Nuli Xie, Jing Li, Kemin Wang
Innovative techniques to visualize native microRNAs (miRNAs) in live cells can dramatically impact current research on the roles of miRNA in biology and medicine. Here, we report a novel approach for live-cell miRNA imaging using a biodegradable MnO2 nanosheet-mediated DD-A FRET hybridization chain reaction (HCR). The MnO2 nanosheets can adsorb DNA hairpin probes and deliver them into live cells. After entering cells, the MnO2 nanosheets are degraded by cellular GSH. Then, the target miR-21 triggers cascaded assembly of the liberated hairpin probes into long dsDNA polymers, which brings each two FAMs (donor) and one TAMRA (acceptor) into close proximity to generate significantly enhanced DD-A FRET signals, which was discovered and proven by our previous report...
January 18, 2018: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/29092791/editorial-for-the-special-issue-on-behavior-change-health-and-health-disparities-2017
#18
EDITORIAL
Stephen T Higgins
This Special Issue of Preventive Medicine (PM) is the 4th in a series on behavior change, health, and health disparities, a topic of critical importance to improving U.S. population health. The U.S. ranks near the bottom on measures of population health relative to other industrialized countries despite spending orders of magnitude more on health care than any other nation. Population health experts agree that the area of personal behavior, or lifestyle, such as substance abuse, physical inactivity/obesity, and non-adherence with medical regimens is the single largest contributor to this situation...
November 2017: Preventive Medicine
https://www.readbyqxmd.com/read/29032677/ultrasensitive-ratiometric-homogeneous-electrochemical-microrna-biosensing-via-target-triggered-ru-iii-release-and-redox-recycling
#19
Panpan Gai, Chengcheng Gu, Haiyin Li, Xinzhi Sun, Feng Li
A new label-free and enzyme-free ratiometric homogeneous electrochemical microRNA biosensing platform was constructed via target-triggered Ru(III) release and redox recycling. To design the effective ratiometric dual-signal strategy, [Ru(NH3)6](3+) (Ru(III)), as one of the electroactive probes, was ingeniously entrapped in the pores of the positively charged mesoporous silica nanoparticle (PMSN), and another electroactive probe, [Fe(CN)6](3-) (Fe(III)), was selected to facilitate Ru(III) redox recycling due to its distinctly separated reduction potential and different redox properties...
October 31, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29019798/the-return-to-literature-making-doctors-matter-in-the-new-era-of-medicine
#20
Daniel Marchalik
The rapid explosion of medical knowledge of the 19th and 20th centuries required a transformation in medical education, which, to that point, had been marked by low educational standards. To combat the lack of regulation, the 1910 Flexner Report recommended sweeping reforms. By 1930, students hoping to enroll in a medical school would need to complete courses in chemistry, physics, and biology, leaving little room for the liberal arts.Medicine is once again changing. The impact of artificial intelligence is being felt across all medical fields, and the nature of physicians' jobs in the new landscape of intelligent machines will inevitably also have to change...
December 2017: Academic Medicine: Journal of the Association of American Medical Colleges
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