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https://www.readbyqxmd.com/read/29786940/glycoinformatics-bridging-isolated-islands-in-the-sea-of-data
#1
Ksenia S Egorova, Philip V Toukach
Glycoinformatics is a young scientific branch, which assists the scientific community in carbohydrate research. In spite of fundamental roles of glycans in living organisms, the informatization of the field is significantly hindered by the lack of standards, data indices, protocols and tools widely recognized by researchers and publishers. The connection of the existing glycoinformatics projects with each other and with global life-science projects is far from complete. Moreover, in contrast to genes and proteins, there is no obligatory unique identifier for each natural carbohydrate structure...
May 22, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29785971/community-noise-exposure-and-annoyance-activity-interference-and-academic-achievement-among-university-students
#2
Rattapon Onchang, Darryl W Hawker
Background: Noise annoyance and effects on academic performance have been investigated for primary and secondary school students but comparatively little work has been conducted with university students who generally spend more time in dormitories or accommodation for their self-study. Objective: To determine, using a socio-acoustic approach involving face-to-face interviews and actual noise measurements, the effect of various community noise sources on student activities in accommodation both inside and outside a university precinct and also relationships with cumulative grade point average (GPA)...
May 2018: Noise & Health
https://www.readbyqxmd.com/read/29785358/bacterial-community-changes-in-an-industrial-algae-production-system
#3
Scott P Fulbright, Adam Robbins-Pianka, Donna Berg-Lyons, Rob Knight, Kenneth F Reardon, Stephen T Chisholm
While microalgae are a promising feedstock for production of fuels and other chemicals, a challenge for the algal bioproducts industry is obtaining consistent, robust algae growth. Algal cultures include complex bacterial communities and can be difficult to manage because specific bacteria can promote or reduce algae growth. To overcome bacterial contamination, algae growers may use closed photobioreactors designed to reduce the number of contaminant organisms. Even with closed systems, bacteria are known to enter and cohabitate, but little is known about these communities...
April 2018: Algal Research
https://www.readbyqxmd.com/read/29785219/assessing-methanogenic-archaeal-community-in-full-scale-anaerobic-sludge-digester-systems-in-dubai-united-arab-emirates
#4
Munawwar A Khan, Poojabahen G Patel, Arpitha G Ganesh, Naushad Rais, Sultan M Faheem, Shams T Khan
Introduction: Anaerobic digestion for methane production comprises of an exceptionally diverse microbial consortium, a profound understanding about which is still constrained. In this study, the methanogenic archaeal communities in three full-scale anaerobic digesters of a Municipal Wastewater Treatment Plant were analyzed by Fluorescence in situ hybridization and quantitative real-time Polymerase Chain Reaction (qPCR) technique. Methods & Materials: Fluorescence in situ hybridization (FISH) was performed to detect and quantify the methanogenic Archaea in the sludge samples whereas qPCR was carried out to support the FISH analysis...
2018: Open Microbiology Journal
https://www.readbyqxmd.com/read/29785214/etiological-trends-and-patterns-of-antimicrobial-resistance-in-respiratory-infections
#5
Salma M Al-Zain Ahmed, Sara S Abdelrahman, Doua M Saad, Isra S Osman, Modasir G Osman, Eltahir A G Khalil
Background: Respiratory infections are one of the commonest causes of morbidity and mortality related to infectious diseases worldwide. The emergence of antimicrobial resistance is a major global health problem which is well established in developing countries. Good clinical suspicion and correct laboratory identification of respiratory infection causing organisms followed by the appropriate management are needed to compact both community-acquired and nosocomial infection respiratory infections...
2018: Open Microbiology Journal
https://www.readbyqxmd.com/read/29784519/east-african-perceptions-of-barriers-facilitators-for-pediatric-clinical-research-participation-and-development-of-the-inclusive-research-model
#6
M Rebecca O'Connor, Ali Adem, Helene Starks
PURPOSE: This study sought to gain a greater understanding of perceptions related to barriers/facilitators for pediatric (ages 0-17) clinical research participation among East African immigrant community members. DESIGN AND METHODS: Community leader interviews (n = 6) and focus groups with lay members (n = 16) from the three largest East African communities in the Seattle area (Eritrean, Ethiopian and Somali) were conducted. Discussions were semi-structured based on existing barrier/facilitator research and analyzed using directed content analysis to identify major themes...
May 18, 2018: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29783945/samsa2-a-standalone-metatranscriptome-analysis-pipeline
#7
Samuel T Westreich, Michelle L Treiber, David A Mills, Ian Korf, Danielle G Lemay
BACKGROUND: Complex microbial communities are an area of growing interest in biology. Metatranscriptomics allows researchers to quantify microbial gene expression in an environmental sample via high-throughput sequencing. Metatranscriptomic experiments are computationally intensive because the experiments generate a large volume of sequence data and each sequence must be compared with reference sequences from thousands of organisms. RESULTS: SAMSA2 is an upgrade to the original Simple Annotation of Metatranscriptomes by Sequence Analysis (SAMSA) pipeline that has been redesigned for standalone use on a supercomputing cluster...
May 21, 2018: BMC Bioinformatics
https://www.readbyqxmd.com/read/29783785/effects-of-pb-smelting-on-the-soil-bacterial-community-near-a-secondary-lead-plant
#8
Zhanbin Luo, Jing Ma, Fu Chen, Xiaoxiao Li, Shaoliang Zhang
Secondary lead smelting is a widespread industrial activity which has exacerbated Pb or Cd contamination of soil and water across the world. Soil physicochemical properties, soil enzyme activities, heavy metal concentrations, and bacterial diversity near a secondary lead plant in Xuzhou, China were examined in this study. The results showed that secondary lead smelting activities influenced nearby soils. Soil acidification decreased one order of magnitude, with a mean value of 7.3. Soil organic matter also showed a downward trend, while potassium and nitrogen appeared to accumulate...
May 20, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29783091/mind-at-home-streamlined-study-protocol-for-a-randomized-trial-of-home-based-care-coordination-for-persons-with-dementia-and-their-caregivers
#9
Quincy M Samus, Betty Smith Black, Melissa Reuland, Jeannie-Marie S Leoutsakos, Laura Pizzi, Kevin D Frick, David L Roth, Laura N Gitlin, Constantine G Lyketsos, Deirdre Johnston
BACKGROUND: Dementia is associated with high health care costs, premature long-term care (LTC) placement, medical complications, reduced quality of life, and caregiver burden. Most health care providers and systems are not yet organized or equipped to provide comprehensive long-term care management for dementia, although a range of effective symptoms and supportive care approaches exist. The Maximizing Independence at Home-Streamlined (MIND-S) is a promising model of home-based dementia care coordination designed to efficiently improve person-centered outcomes, while reducing care costs...
May 18, 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29782820/onchocerciasis-prevalence-human-migration-and-risks-for-onchocerciasis-elimination-in-the-upper-mouhoun-nakamb%C3%A3-and-nazinon-river-basins-in-burkina-faso
#10
Achille S Nikièma, Lassane Koala, Rory J Post, Alain B Paré, Claude Montant Kafando, François Drabo, Adrien M G Belem, Roch K Dabiré, Soungalo Traoré
Historically, the whole of Burkina Faso was considered to be endemic for onchocerciasis (except a small area in the far north of the country) with prevalence rates 60-80%, but all endemic areas were included in the World Health Organisation Onchocerciasis Control Programme, which operated a system of vector control by larviciding beginning in 1974. In Burkina Faso larviciding had been phased out by 1989 when it was considered that onchocerciasis had been reduced to levels below the transmission breakpoint (and any residual infections would disappear without further intervention)...
May 18, 2018: Acta Tropica
https://www.readbyqxmd.com/read/29782390/suspecting-hyperferritinemic-sepsis-in-iron-deficient-population-do-we-need-a-lower-plasma-ferritin-threshold
#11
Swarup Ghosh, Arun K Baranwal, Prateek Bhatia, Karthi Nallasamy
OBJECTIVES: Hyperferritinemia is being suggested to identify patients with sepsis-induced macrophage activation syndrome for early intervention. However, data among iron-deficient children are scarce. This study was planned to explore the biological behavior of plasma ferritin in children from communities with a high frequency of iron deficiency with septic shock and its association with the outcome. DESIGN: Prospective observational study. SETTING: Tertiary care teaching hospital in a low-middle income economy of South Asia...
May 18, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29781923/going-beyond-clinical-care-to-reduce-health-care-spending-findings-from-the-j-chip-community-based-population-health-management-program-evaluation
#12
Shannon M E Murphy, Douglas E Hough, Martha L Sylvia, Melissa Sherry, Linda J Dunbar, Raymond Zollinger, Regina Richardson, Scott A Berkowitz, Kevin D Frick
BACKGROUND: Addressing both clinical and nonclinical determinants of health is essential for improving population health outcomes. In 2012, the Johns Hopkins Community Health Partnership (J-CHiP) implemented innovative population health management programs across acute and community environments. The community-based program involved multidisciplinary teams [ie, physicians, care managers (CM), health behavior specialists (HBS), community health workers, neighborhood navigators] and collaboration with community-based organizations to address social determinants...
May 17, 2018: Medical Care
https://www.readbyqxmd.com/read/29781685/detection-referral-and-control-of-diabetes-and-hypertension-in-the-rural-eastern-cape-province-of-south-africa-by-community-health-outreach-workers-in-the-rural-primary-healthcare-project-health-in-every-hut
#13
Angela A Morris-Paxton, Paul Rheeder, Rose-Marie G Ewing, Dillon Woods
BACKGROUND:  Non-communicable diseases, mainly cardiovascular diseases, diabetes, cancer and chronic respiratory diseases, are responsible for approximately 63% of all deaths occurring worldwide in any given year. The majority of these deaths have occurred in low- and middle-income countries (LMICs). The latest World Health Organization (WHO) report shows that the increase in diabetes is also most pronounced in the LMICs. The South African Labour and Development Research Unit estimated a 9% prevalence within the adult population in 2016...
April 11, 2018: African Journal of Primary Health Care & Family Medicine
https://www.readbyqxmd.com/read/29781421/molecular-phylogeny-based-on-six-nuclear-genes-suggests-that-echinococcus-granulosus-sensu-lato-genotypes-g6-g7-and-g8-g10-can-be-regarded-as-two-distinct-species
#14
Teivi Laurimäe, Liina Kinkar, Epp Moks, Thomas Romig, Rihab A Omer, Adriano Casulli, Gérald Umhang, Guna Bagrade, Malik Irshadullah, Mitra Sharbatkhori, Hossein Mirhendi, Francisco Ponce-Gordo, Silvia V Soriano, Antonio Varcasia, Mohammad Rostami-Nejad, Vanessa Andresiuk, Urmas Saarma
Tapeworms of the species complex of Echinococcus granulosus sensu lato (s. l.) are the cause of a severe zoonotic disease - cystic echinococcosis, which is listed among the most severe parasitic diseases in humans and is prioritized by the World Health Organization. A stable taxonomy of E. granulosus s. l. is essential to the medical and veterinary communities for accurate and effective communication of the role of different species in this complex on human and animal health. E. granulosus s. l. displays high genetic diversity and has been divided into different species and genotypes...
May 21, 2018: Parasitology
https://www.readbyqxmd.com/read/29781372/chinese-perspectives-on-primary-care-for-common-mental-disorders-barriers-and-policy-implications
#15
Kai Sing Sun, Tai Pong Lam, Dan Wu
BACKGROUND: The World Health Organization (WHO) has called for integration of mental health into primary care for a decade. In Western countries, around 15% to 25% of patients with common mental disorders including mood and anxiety disorders seek help from primary care physicians (PCPs). The rate is only about 5% in China. AIMS: This article reviews the Chinese findings on the barriers to primary care for common mental disorders and how they compared with Western findings...
May 1, 2018: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/29780856/the-role-of-meaning-in-life-for-the-quality-of-life-of-community-dwelling-chinese-elders-with-low-socioeconomic-status
#16
Raymond Chi-Fai Chui
Objectives: There is limited research on the meaning in life among Chinese elders. This study aims to examine the association among functional disabilities, meaning in life, social network, and quality of life in community-dwelling Chinese elders with low socioeconomic status. Methods: A cross-sectional survey was used to collect data from 339 poor community-dwelling Chinese elders aged 60 and above. Results: The results showed that meaning in life and social network were significantly related to quality of life...
January 2018: Gerontology & Geriatric Medicine
https://www.readbyqxmd.com/read/29780833/the-growing-genetic-and-functional-diversity-of-extended-spectrum-beta-lactamases
#17
REVIEW
Sadeeq Ur Rahman, Tariq Ali, Ijaz Ali, Nazir Ahmad Khan, Bo Han, Jian Gao
The β -lactams-a large class of diverse compounds-due to their excellent safety profile and broad antimicrobial spectrum are considered to be the most widely used therapeutic class of antibacterials prescribed in human and veterinary clinical practices. This, unfortunately, has also given rise to a continuous increased resistance globally in health care settings as well as in the community due to their permanent selective force driving diversification of the resistance mechanism. Resistance against β -lactams is increasing rapidly as novel β -lactamases, enzymes that degrade β -lactams, are being discovered each day such as recent emergence of extended spectrum β -lactamases (ESBL) that have the ability to inactivate most of the cephalosporins...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29780584/opening-the-black-box-of-spring-water-microbiology-from-alpine-karst-aquifers-to-support-proactive-drinking-water-resource-management
#18
REVIEW
Domenico Savio, Philipp Stadler, Georg H Reischer, Alexander K T Kirschner, Katalin Demeter, Rita Linke, Alfred P Blaschke, Regina Sommer, Ulrich Szewzyk, Inés C Wilhartitz, Robert L Mach, Hermann Stadler, Andreas H Farnleitner
Over the past 15 years, pioneering interdisciplinary research has been performed on the microbiology of hydrogeologically well-defined alpine karst springs located in the Northern Calcareous Alps (NCA) of Austria. This article gives an overview on these activities and links them to other relevant research. Results from the NCA springs and comparable sites revealed that spring water harbors abundant natural microbial communities even in aquifers with high water residence times and the absence of immediate surface influence...
May 2018: WIREs. Water
https://www.readbyqxmd.com/read/29780374/insight-into-the-variation-of-bacterial-structure-in-atrazine-contaminated-soil-regulating-by-potential-phytoremediator-pennisetum-americanum-l-k-schum
#19
Bo Cao, Ying Zhang, Ziyi Wang, Mengyuan Li, Feng Yang, Duo Jiang, Zhao Jiang
Although plants of the genus Pennisetum can accelerate the removal of atrazine from its rhizosphere, the roles played by this plant in adjusting the soil environment and soil microorganism properties that might contribute to pollutant removal are incompletely understood. We selected Pennisetum americanum (L.) K. Schum ( P. americanum ) as the test plant and investigated the interaction between P. americanum and atrazine-contaminated soil, focusing on the adjustment of the soil biochemical properties as well as bacterial functional and community diversity in the rhizosphere using Biolog EcoPlates and high-throughput sequencing of the 16S rRNA gene...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29780265/does-focused-and-dedicated-teaching-improve-the-confidence-of-gp-trainees-to-diagnose-and-manage-common-acute-ent-pathologies-in-primary-care
#20
Vikas Acharya, Matthew Haywood, Naomi Kokkinos, Anisha Raithatha, Sinthuja Francis, Rishi Sharma
Background: General practitioners (GPs) are key members of the health care profession who are required to have a considerable breadth of knowledge to manage and treat patients effectively in the community. Their skills and experience varies depending on the medical school they attended and their foundation training and specialist GP training schemes. Exposure to ear, nose, and throat (ENT)-specific pathology is often insufficient due to the lack of formal otolaryngology rotations, minimal relevant teaching opportunities, and inconsistencies in curricula, despite ENT-related pathology presentations being one of the commonest consultations in primary care...
2018: Advances in Medical Education and Practice
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