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https://www.readbyqxmd.com/read/28231620/sustaining-guideline-implementation-a-multi-site-perspective-on-activities-challenges-and-supports
#1
Kathryn Smith Higuchi, Barbara Davies, Jenny Ploeg
AIMS AND OBJECTIVES: To examine activities conducted, challenges encountered, and supports used when sustaining nursing practice guideline implementation in multiple health care organizations over three years. BACKGROUND: Numerous models and frameworks exist to guide the implementation of guidelines, yet very few focus on sustaining improved practice changes. It is not known if one intervention or multiple interventions are required, nor the long-term activities, challenges, and supports for sustaining improved practices...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231311/handwashing-and-ebola-virus-disease-outbreaks-a-randomized-comparison-of-soap-hand-sanitizer-and-0-05-chlorine-solutions-on-the-inactivation-and-removal-of-model-organisms-phi6-and-e-coli-from-hands-and-persistence-in-rinse-water
#2
Marlene K Wolfe, Karin Gallandat, Kyle Daniels, Anne Marie Desmarais, Pamela Scheinman, Daniele Lantagne
To prevent Ebola transmission, frequent handwashing is recommended in Ebola Treatment Units and communities. However, little is known about which handwashing protocol is most efficacious. We evaluated six handwashing protocols (soap and water, alcohol-based hand sanitizer (ABHS), and 0.05% sodium dichloroisocyanurate, high-test hypochlorite, and stabilized and non-stabilized sodium hypochlorite solutions) for 1) efficacy of handwashing on the removal and inactivation of non-pathogenic model organisms and, 2) persistence of organisms in rinse water...
2017: PloS One
https://www.readbyqxmd.com/read/28230161/robust-high-dimensional-bioinformatics-data-streams-mining-by-odr-iovfdt
#3
Dantong Wang, Simon Fong, Raymond K Wong, Sabah Mohammed, Jinan Fiaidhi, Kelvin K L Wong
Outlier detection in bioinformatics data streaming mining has received significant attention by research communities in recent years. The problems of how to distinguish noise from an exception and deciding whether to discard it or to devise an extra decision path for accommodating it are causing dilemma. In this paper, we propose a novel algorithm called ODR with incrementally Optimized Very Fast Decision Tree (ODR-ioVFDT) for taking care of outliers in the progress of continuous data learning. By using an adaptive interquartile-range based identification method, a tolerance threshold is set...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28229205/-spectrum-of-pathogens-in-postoperative-complications-of-visceral-surgery-the-problem-of-multidrug-resistance
#4
A Kramer, J Pochhammer, P Walger, U Seifert, M Ruhnke, J C Harnoss
In general surgery the etiology of surgical site infections has not significantly changed over the last 30 years. Gram-positive bacteria, e.g. coagulase negative staphylococci (CNS), Staphylococcus aureus and Enterococcus spp. as well as Gram-negative bacteria, e.g. Escherichia coli, Enterobacter spp., Klebsiella spp. and Pseudomonas aeruginosa, are the most common findings. Although in general surgery 10% of the S. aureus causing postoperative wound infections were methicillin resistant (MRSA), no cases of multidrug-resistant Gram-negative (MRGN) bacteria were reported...
February 22, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/28229194/screening-level-assessment-of-metal-concentrations-in-streambed-sediments-and-floodplain-soils-within-the-grand-lake-watershed-in-northeastern-oklahoma-usa
#5
Ean M Garvin, Cas F Bridge, Meredith S Garvin
Metal releases have been received by the Grand Lake watershed from the Tri-State Mining District (TSMD) since the mid 1800s. To address data gaps in metal distributions in the Oklahoma portion of the watershed, streambed sediment and floodplain soil was sampled on various streams. The <63-µm fraction was analyzed for Cd, Pb, and Zn concentrations by portable X-ray fluorescence spectroscopy and inductively coupled plasma-mass spectrometry. Mean metal concentration results at reference transects indicated that background sediment/soil concentrations for Cd, Pb, and Zn within the watershed were 0...
February 22, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28228969/prevention-and-treatment-of-neonatal-nosocomial-infections
#6
REVIEW
Jayashree Ramasethu
Nosocomial or hospital acquired infections threaten the survival and neurodevelopmental outcomes of infants admitted to the neonatal intensive care unit, and increase cost of care. Premature infants are particularly vulnerable since they often undergo invasive procedures and are dependent on central catheters to deliver nutrition and on ventilators for respiratory support. Prevention of nosocomial infection is a critical patient safety imperative, and invariably requires a multidisciplinary approach. There are no short cuts...
2017: Maternal Health, Neonatology and Perinatology
https://www.readbyqxmd.com/read/28228070/nanoscale-delivery-systems-actual-and-potential-applications-in-the-natural-products-industry
#7
Antal Diana Simona, Ardelean Florina, Chis Aimée Rodica, Ollivier Evelyne, Serban Maria-Corina
BACKGROUND: Compounds and extracts derived from natural sources continue to stand in the spotlight of drug design owing to their versatile interaction with enzymes, receptors and metabolic pathways. Nanomedicine offers an operative tool for the efficient delivery of natural products, in terms of increased bioavailability, targeting, and controlled release while protecting active constituents against physico-chemical alterations. The interest of the scientific community in the field of nanosized delivery of natural compounds is demonstrated by the exponential growth of the publications in this field...
February 20, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28227254/a-data-science-approach-for-quantifying-spatio-temporal-effects-to-graft-failures-in-organ-transplantation
#8
Diego Pinheiro, Farag Hamad, Martin Cadeiras, Ronaldo Menezes, Nezamoddin Nezamoddini-Kachouie, Diego Pinheiro, Farag Hamad, Martin Cadeiras, Ronaldo Menezes, Nezamoddin Nezamoddini-Kachouie, Farag Hamad, Martin Cadeiras, Diego Pinheiro, Ronaldo Menezes, Nezamoddin Nezamoddini-Kachouie
The transplantation of solid organs is one of the most important accomplishments of modern medicine. Yet, organ shortage is a major public health issue; 8,000 people died while waiting for an organ in 2014. Meanwhile, the allocation system currently implemented can lead to organs being discarded and the medical community still investigates factors that affects early graft failure such as distance and ischemic time. In this paper, we investigate early graft failure under a spatio-temporal perspective using a data science unified approach for all six organs that is based on complementary cumulative analysis of both distance and ischemic time...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226321/inhalant-allergens-in-portugal
#9
Irene Gomes Câmara Camacho
This review aims to present in a simple manner the work performed in Portugal regarding the identification of the most prevalent aeroallergens in the country and the sensitization levels in Portuguese patients. Much of the data was summarized in tables and illustrated on maps, enabling the community of clinicians, researchers, and patient organizations to access the knowledge about the research performed. This study provides an overview about the distribution of aeroallergens in Portugal, signaling regions and critical periods of exposure of the sensitized population...
February 23, 2017: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/28226283/social-ecological-correlates-of-polyvictimization-among-a-national-sample-of-transgender-genderqueer-and-cisgender-sexual-minority-adolescents
#10
Paul R Sterzing, G Allen Ratliff, Rachel E Gartner, Briana L McGeough, Kelly C Johnson
Polyvictimization is a common experience for youth in the United States, with 20% nationally experiencing five or more different forms of victimization in the last year. Utilizing a large, national convenience sample of sexual and gender minority adolescents (N = 1177, 14-19 years old), the current study aimed to (a) generate the first estimates of last year polyvictimization (including nine victimization subtypes) for transgender, genderqueer, and cisgender (i.e., assigned birth sex aligns with gender identity) sexual minority adolescents and (b) identify social ecological correlates of last year polyvictimization...
February 18, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28225542/historical-overview-of-leprosy-control-in-cuba
#11
Enrique Beldarraín-Chaple
INTRODUCTION Leprosy, an infectious disease caused by Mycobacterium leprae, affects the nervous system, skin, internal organs, extremities and mucous membranes. Biological, social and environmental factors influence its occurrence and transmission. The first effective treatments appeared in 1930 with the development of dapsone, a sulfone. The main components of a control and elimination strategy are early case detection and timely administration of multidrug therapy. OBJECTIVES Review the history of leprosy control in Cuba, emphasizing particularly results of the National Leprosy Control Program, its modifications and influence on leprosy control...
January 2017: MEDICC Review
https://www.readbyqxmd.com/read/28225262/temperature-decouples-ammonium-and-nitrite-oxidation-in-coastal-waters
#12
Sylvia C Schaefer, James T Hollibaugh
Nitrification is a two-step process linking the reduced and oxidized sides of the nitrogen cycle. These steps are typically tightly coupled with the primary intermediate, nitrite, rarely accumulating in coastal environments. Nitrite concentrations can exceed 10 µM during summer in estuarine waters adjacent to Sapelo Island, Georgia, USA. Similar peaks at other locations have been attributed to decoupling of the two steps of nitrification by hypoxia; however, the waters around Sapelo Island are aerobic and well-mixed...
February 22, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28224627/nitrogen-deposition-cancels-out-exotic-earthworm-effects-on-plant-feeding-nematode-communities
#13
Yuanhu Shao, Weixin Zhang, Nico Eisenhauer, Tao Liu, Yanmei Xiong, Chenfei Liang, Shenglei Fu
1.The activity and spread of exotic earthworms often are spatially correlated with N deposition because both arise from human activities. Exotic earthworms, in turn, can also greatly affect soil abiotic and biotic properties, as well as related ecological processes. Previous studies showed, for example, that earthworms can counteract the detrimental effects of plant-feeding nematodes on plant growth. However, potential interactive effects of N deposition and exotic earthworms on ecosystems are poorly understood...
February 21, 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/28224221/-reaching-elderly-migrants-where-they-live-experiences-from-the-swiss-vicino-project
#14
S Johner-Kobi, M Gehrig
BACKGROUND: Community involvement through formal and informal networks is an important resource of support for elderly people with or without a migrant background, particularly as they get older. In the research and development project "Vicino - reaching elderly migrants where they live" the factors for success and failure in the cooperation between public institutions (organizations which do not focus on a specific group of migrants but are accessible for everybody) and migrant organizations were identified by means of three participatory interventions...
February 21, 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28223966/geological-and-geochemical-controls-on-subsurface-microbial-life-in-the-samail-ophiolite-oman
#15
Kaitlin R Rempfert, Hannah M Miller, Nicolas Bompard, Daniel Nothaft, Juerg M Matter, Peter Kelemen, Noah Fierer, Alexis S Templeton
Microbial abundance and diversity in deep subsurface environments is dependent upon the availability of energy and carbon. However, supplies of oxidants and reductants capable of sustaining life within mafic and ultramafic continental aquifers undergoing low-temperature water-rock reaction are relatively unknown. We conducted an extensive analysis of the geochemistry and microbial communities recovered from fluids sampled from boreholes hosted in peridotite and gabbro in the Tayin block of the Samail Ophiolite in the Sultanate of Oman...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28223457/the-source-and-evolutionary-history-of-a-microbial-contaminant-identified-through-soil-metagenomic-analysis
#16
Matthew R Olm, Cristina N Butterfield, Alex Copeland, T Christian Boles, Brian C Thomas, Jillian F Banfield
In this study, strain-resolved metagenomics was used to solve a mystery. A 6.4-Mbp complete closed genome was recovered from a soil metagenome and found to be astonishingly similar to that of Delftia acidovorans SPH-1, which was isolated in Germany a decade ago. It was suspected that this organism was not native to the soil sample because it lacked the diversity that is characteristic of other soil organisms; this suspicion was confirmed when PCR testing failed to detect the bacterium in the original soil samples...
February 21, 2017: MBio
https://www.readbyqxmd.com/read/28223377/exopolysaccharide-repressing-small-molecules-with-antibiofilm-and-antivirulence-activity-against-pseudomonas-aeruginosa
#17
Erik van Tilburg Bernardes, Laetitia Charron-Mazenod, David J Reading, Shauna L Reckseidler-Zenteno, Shawn Lewenza
Biofilm formation is a universal virulence strategy in which bacteria grow in dense microbial communities enmeshed within a polymeric extracellular matrix that protects them from antibiotic exposure and the immune system. Pseudomonas aeruginosa is an archetypal biofilm-forming organism that utilizes a biofilm growth strategy to cause chronic lung infections in Cystic Fibrosis (CF) patients. The extracellular matrix of P. aeruginosa biofilms is comprised mainly of exopolysaccharides (EPS) and DNA. Both mucoid and non-mucoid isolates of P...
February 21, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28222375/on-site-nutrient-recovery-and-removal-from-source-separated-urine-by-phosphorus-precipitation-and-short-cut-nitrification-denitrification
#18
Song Yao, Liping Chen, Detian Guan, Zhongguo Zhang, Xiujun Tian, Aimin Wang, Guotian Wang, Qian Yao, Dangcong Peng, Jiuyi Li
Source separation and treatment of human urine have been recognized as a resource-efficient alternative to conventional urban drainage, not only reducing nutrient loads on municipal wastewater treatment plants, but recovering valuable resources from waste streams. In this work, on-site phosphorus (P) recovery from real urine was carried out by using the brine from a reverse osmosis process as the flush water for urine-diverting toilets and a P precipitant, while nitrogen (N) was removed via short-cut nitrification-denitrification (SCND) in a membrane bioreactor (MBR)...
February 16, 2017: Chemosphere
https://www.readbyqxmd.com/read/28222236/differential-sharing-and-distinct-co-occurrence-networks-among-spatially-close-bacterial-microbiota-of-bark-mosses-and-lichens%C3%A2-%C3%A2
#19
Ines Aline Aschenbrenner, Tomislav Cernava, Armin Erlacher, Gabriele Berg, Martin Grube
Knowledge of bacterial community host-specificity has increased greatly in recent years. However, the inter-microbiome relationships of unrelated but spatially close organisms remain little understood. Trunks of trees covered by epiphytes represent complex habitats with a mosaic of ecological niches. In this context, we investigated the structure, diversity and interactions of microbiota associated with lichens, mosses and the bare tree bark. Comparative analysis revealed significant differences in the habitat-associated community structures...
February 21, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28222117/two-dynamic-regimes-in-the-human-gut-microbiome
#20
Sean M Gibbons, Sean M Kearney, Chris S Smillie, Eric J Alm
The gut microbiome is a dynamic system that changes with host development, health, behavior, diet, and microbe-microbe interactions. Prior work on gut microbial time series has largely focused on autoregressive models (e.g. Lotka-Volterra). However, we show that most of the variance in microbial time series is non-autoregressive. In addition, we show how community state-clustering is flawed when it comes to characterizing within-host dynamics and that more continuous methods are required. Most organisms exhibited stable, mean-reverting behavior suggestive of fixed carrying capacities and abundant taxa were largely shared across individuals...
February 21, 2017: PLoS Computational Biology
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