J J Bernstein
The feasibility for growth, maturation, and differentiation of fetal nervous system implanted into adult mammalian peripheral nervous system was studied. Thirty-five adult rats had the epineurium of the sciatic nerve crushed, perineurium minced, and fetal rat cortex or spinal cord implanted. Rats were utilized 7, 14, and 21 days, and 1, 2, 3, and 4 months later. A 1-mm cube of cortex or a 1-mm segment of spinal cord of 11-, 12-, or 15-day gestation fetuses was placed into the epineurium. Age-matched controls (7 DPI (days postimplantation) control for E15 implant was a 1-day pup, 21 days' gestation) were utilized for comparison (two per time group)...
1983: Journal of Neuroscience Research